ATE544070T1 - Verfahren zum nachweis von tumorspezifischen fusionsproteinen - Google Patents

Verfahren zum nachweis von tumorspezifischen fusionsproteinen

Info

Publication number
ATE544070T1
ATE544070T1 AT09731266T AT09731266T ATE544070T1 AT E544070 T1 ATE544070 T1 AT E544070T1 AT 09731266 T AT09731266 T AT 09731266T AT 09731266 T AT09731266 T AT 09731266T AT E544070 T1 ATE544070 T1 AT E544070T1
Authority
AT
Austria
Prior art keywords
fusion proteins
specific fusion
detecting tumor
detection
relates
Prior art date
Application number
AT09731266T
Other languages
English (en)
Inventor
Dongen Jacobus Johannes Maria Van
Original Assignee
Univ Erasmus Medical Ct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Erasmus Medical Ct filed Critical Univ Erasmus Medical Ct
Application granted granted Critical
Publication of ATE544070T1 publication Critical patent/ATE544070T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57505—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the blood, e.g. leukaemia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/82—Translation products from oncogenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT09731266T 2008-04-07 2009-04-06 Verfahren zum nachweis von tumorspezifischen fusionsproteinen ATE544070T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12336908P 2008-04-07 2008-04-07
EP08154164A EP2108956A1 (de) 2008-04-07 2008-04-07 Verbesserte Verfahren und Kits zum Erkennen von tumorspezifischen Fusionsproteinen
PCT/EP2009/054072 WO2009124901A1 (en) 2008-04-07 2009-04-06 Methods and kits for detecting tumor-specific fusion proteins

Publications (1)

Publication Number Publication Date
ATE544070T1 true ATE544070T1 (de) 2012-02-15

Family

ID=39764992

Family Applications (1)

Application Number Title Priority Date Filing Date
AT09731266T ATE544070T1 (de) 2008-04-07 2009-04-06 Verfahren zum nachweis von tumorspezifischen fusionsproteinen

Country Status (5)

Country Link
US (1) US20110027808A1 (de)
EP (2) EP2108956A1 (de)
JP (1) JP2011519022A (de)
AT (1) ATE544070T1 (de)
WO (1) WO2009124901A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX337666B (es) * 2009-10-20 2016-03-14 Nestec Sa Ensayos regulados mediante proximidad para detectar proteinas de fusion oncogenicas.
CN101955991B (zh) * 2010-03-31 2014-05-28 江苏迈迪基因生物科技有限公司 白血病相关的融合基因的联合检测方法及诊断试剂盒
DE102010031923A1 (de) 2010-07-22 2012-01-26 Giesecke & Devrient Gmbh Sicherheitsfaden für Datenträger sowie Datenträger und deren Herstellung
US20140080154A1 (en) * 2011-04-15 2014-03-20 Vivabiocell S.P.A. Immunodiagnostic method for diagnosing auto-immune systemic sclerosis (ssc) and systemic lupus erythematosus (sle)
KR101439856B1 (ko) * 2011-06-02 2014-09-17 한국생명공학연구원 항-ａｔｉｃ 자가면역항체를 포함하는 간암 진단 마커 및 이의 항원을 포함하는 간암 진단용 조성물
WO2014130975A1 (en) * 2013-02-22 2014-08-28 Bastian Boris C Fusion polynucleotides and fusion polypeptides associated with cancer and particularly melanoma and their uses as therapeutic and diagnostic targets
AU2017376450B2 (en) 2016-12-13 2024-05-23 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods of treating cells containing fusion genes by genomic targeting
JP7042045B2 (ja) * 2017-08-10 2022-03-25 シスメックス株式会社 試料分析装置
WO2025096203A1 (en) * 2023-10-30 2025-05-08 University Of Virginia Patent Foundation Targeting a chimeric rna for treating cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78703A (en) 1985-05-10 1993-02-21 Benzon Alfred Method of producing extracellular enzymes, the enzymes produced thereby and compositions containing them; a hybrid plasmid and a dna fragment comprising dna encoding the enzymes; a microorganism harbouring the plasmid; and a method for removing nucleic acids from biological materials
US5173418A (en) 1985-05-10 1992-12-22 Benzon Pharma, A/S Production in Escherichia coli of extracellular Serratia spp. hydrolases
US6686165B2 (en) * 1997-05-20 2004-02-03 Erasmus Universiteit Rotterdam Recognition of tumor-specific gene products in cancer
WO2000050903A1 (en) 1999-02-24 2000-08-31 Luminex Corporation Particulate solid phase immobilized protein quantitation
US7262283B2 (en) 2002-09-02 2007-08-28 Merck Patent Gmbh Method for extracting proteins
JP2007523621A (ja) * 2003-06-18 2007-08-23 オニックス ファーマシューティカルズ，インコーポレイティド ウイルスを精製するための方法
EP1507147A1 (de) 2003-08-12 2005-02-16 Erasmus University Medical Center Rotterdam Verfahren zum Nachweiss von niedrigem Gehalt an Fusionsprotein
US20070015134A1 (en) * 2005-07-15 2007-01-18 Beckman Coulter, Inc. Quantitative stabilized cell reference control products and methods
US8124351B2 (en) * 2005-11-18 2012-02-28 Board Of Regents, The University Of Texas System Quantification of fusion proteins and their activity from chromosomal translocation

Also Published As

Publication number Publication date
WO2009124901A8 (en) 2011-04-14
EP2260304B1 (de) 2012-02-01
JP2011519022A (ja) 2011-06-30
WO2009124901A1 (en) 2009-10-15
US20110027808A1 (en) 2011-02-03
EP2260304A1 (de) 2010-12-15
EP2108956A1 (de) 2009-10-14

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