ATE544461T1 - Rekonstituierte tenside mit verbesserten eigenschaften - Google Patents

Rekonstituierte tenside mit verbesserten eigenschaften

Info

Publication number
ATE544461T1
ATE544461T1 AT08758696T AT08758696T ATE544461T1 AT E544461 T1 ATE544461 T1 AT E544461T1 AT 08758696 T AT08758696 T AT 08758696T AT 08758696 T AT08758696 T AT 08758696T AT E544461 T1 ATE544461 T1 AT E544461T1
Authority
AT
Austria
Prior art keywords
improved properties
directed
amino acid
reconstituted surfactants
polypeptide
Prior art date
Application number
AT08758696T
Other languages
English (en)
Inventor
Jan Johansson
Tore Curstedt
Bengt Robertson
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Application granted granted Critical
Publication of ATE544461T1 publication Critical patent/ATE544461T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Fire-Extinguishing Compositions (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
AT08758696T 2007-06-01 2008-05-22 Rekonstituierte tenside mit verbesserten eigenschaften ATE544461T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07010857A EP1997502A1 (de) 2007-06-01 2007-06-01 Rekonstituierte Tenside mit verbesserten Eigenschaften
PCT/EP2008/004097 WO2008145298A1 (en) 2007-06-01 2008-05-22 Reconstituted surfactants having improved properties

Publications (1)

Publication Number Publication Date
ATE544461T1 true ATE544461T1 (de) 2012-02-15

Family

ID=38421186

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08758696T ATE544461T1 (de) 2007-06-01 2008-05-22 Rekonstituierte tenside mit verbesserten eigenschaften

Country Status (13)

Country Link
US (1) US7897577B2 (de)
EP (2) EP1997502A1 (de)
JP (1) JP5575639B2 (de)
KR (1) KR101516443B1 (de)
CN (1) CN101687006B (de)
AT (1) ATE544461T1 (de)
AU (1) AU2008256449B2 (de)
BR (1) BRPI0811320A2 (de)
CA (1) CA2689066C (de)
EA (1) EA017697B1 (de)
MX (1) MX2009012675A (de)
WO (1) WO2008145298A1 (de)
ZA (1) ZA200908445B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20021058A1 (it) 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
RS53172B (sr) * 2006-10-13 2014-06-30 Chiesi Farmaceutici S.P.A. Rekonstituisani surfaktanti sa poboljšanim svojstvima
EP2022798A1 (de) 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetische Lungensurfactant-Peptide
WO2009049159A1 (en) 2007-10-10 2009-04-16 Parion Sciences, Inc. Delivering osmolytes by nasal cannula
US8399406B2 (en) * 2009-06-05 2013-03-19 Chiesi Farmaceutici S.P.A. Reconstituted surfactant composition containing analogs of surfactant protein B (SP-B) and surfactant protein C (SP-C)
CA2838529C (en) 2011-06-07 2020-03-24 Parion Sciences, Inc. Methods of treatment
US8945605B2 (en) 2011-06-07 2015-02-03 Parion Sciences, Inc. Aerosol delivery systems, compositions and methods
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
CA2867649C (en) 2012-03-28 2021-02-16 Discovery Laboratories, Inc. Lyophilization of synthetic liposomal pulmonary surfactant
EA201990616A3 (ru) 2012-05-29 2019-12-30 Парион Сайэнс, Инк. Дендримероподобные аминоамиды, обладающие активностью блокаторов натриевых каналов, для лечения сухости глаз и других заболеваний слизистых оболочек
CN105073717B (zh) 2012-12-17 2018-05-22 帕里昂科学公司 可用于治疗由黏膜水化不足造成的疾病的氯-吡嗪甲酰胺衍生物
ES2674665T3 (es) 2012-12-17 2018-07-03 Parion Sciences, Inc. Compuestos de 3,5-diamino-6-cloro-N-(N-(4-fenilbutilo)carbamimidoilo)-pirazina-2-carboxamida
CN108658876A (zh) 2012-12-17 2018-10-16 帕里昂科学公司 3,5-二氨基-6-氯-n-(n-(4-苯基丁基)甲脒基)吡嗪-2-甲酰胺化合物
PL3201341T3 (pl) 2014-10-01 2025-09-01 Plant Health Care, Inc. Peptydy wywołujące reakcję nadwrażliwości i ich zastosowanie
CA2962945A1 (en) 2014-10-01 2016-04-07 Plant Health Care, Inc. Elicitor peptides having disrupted hypersensitive response box and use thereof
BR112018070141A2 (pt) 2016-04-06 2019-02-12 Plant Health Care, Inc. resposta hipersensitiva de peptídeos derivados de eliciador e uso dos mesmos
BR112018069945A2 (pt) 2016-04-06 2019-02-05 Plant Health Care, Inc. micróbios benéficos para distribuição de peptídeos ou proteínas efetoras e uso dos mesmos
JP7777392B2 (ja) 2016-12-22 2025-11-28 キエージ・フアルマチエウテイチ・エツセ・ピ・ア 進行性のｂｐｄの処置のための肺サーファクタント及びステロイドを含む処置的組み合わせ物
MA52353A (fr) 2018-04-23 2021-04-28 Chiesi Farm Spa Combinaison thérapeutique comprenant un tensioactif pulmonaire et un stéroïde pour la prophylaxie de la dbp
US12440471B2 (en) * 2021-07-30 2025-10-14 Ayuvis Research, Inc. Compositions and methods for the treatment of bronchopulmonary dysplasia (BPD) and BPD-associated pulmonary hypertension
WO2025245275A1 (en) * 2024-05-21 2025-11-27 Molecular Express, Inc. Surfactant preparations for pulmonary delivery, and methods for the preparation and use thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260273A (en) 1988-01-06 1993-11-09 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
IT1308180B1 (it) 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
EP1189625A1 (de) * 1999-06-11 2002-03-27 Byk Gulden Lomberg Chemische Fabrik GmbH Pharmazeutische zubereitung enthaltend modifikationen von surfactant protein b (sp-b) und surfactant protein c (sp-c)
KR20110017465A (ko) * 2002-04-25 2011-02-21 더 스크립스 리서치 인스티튜트 폐질환 증상의 치료 및 예방
ITMI20021058A1 (it) * 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
EP1481665A1 (de) * 2003-05-30 2004-12-01 CHIESI FARMACEUTICI S.p.A. Neue Lipidmischungen für synthetische Tenside
US7582312B2 (en) * 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
RS53172B (sr) * 2006-10-13 2014-06-30 Chiesi Farmaceutici S.P.A. Rekonstituisani surfaktanti sa poboljšanim svojstvima
EP2022798A1 (de) 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetische Lungensurfactant-Peptide

Also Published As

Publication number Publication date
KR101516443B1 (ko) 2015-05-07
JP2010528997A (ja) 2010-08-26
AU2008256449A1 (en) 2008-12-04
US20090088379A1 (en) 2009-04-02
JP5575639B2 (ja) 2014-08-20
HK1140420A1 (en) 2010-10-15
ZA200908445B (en) 2011-02-23
KR20100015802A (ko) 2010-02-12
CN101687006A (zh) 2010-03-31
AU2008256449B2 (en) 2012-09-13
EA017697B1 (ru) 2013-02-28
MX2009012675A (es) 2009-12-14
US7897577B2 (en) 2011-03-01
BRPI0811320A2 (pt) 2014-10-21
EP2152288B1 (de) 2012-02-08
CN101687006B (zh) 2013-10-16
EP1997502A1 (de) 2008-12-03
EA200901459A1 (ru) 2010-06-30
EP2152288A1 (de) 2010-02-17
CA2689066C (en) 2016-03-29
CA2689066A1 (en) 2008-12-04
WO2008145298A1 (en) 2008-12-04

Similar Documents

Publication Publication Date Title
ATE544461T1 (de) Rekonstituierte tenside mit verbesserten eigenschaften
TN2009000099A1 (en) Reconstituted surfactants having improved properties
BRPI1010120A2 (pt) composição de surfactante reconstituído melhorada contendo análogos de proteína b do surfactante (sp-b) e proteína c do surfactante ( sp-c)
DK1877435T3 (da) Glucagon-lignende peptid 2 (GLP-2)-analoger
BRPI0813699A2 (pt) Formulações de proteína de fusão glp-1-fc
ATE489462T1 (de) Antimikrobielles polypeptid und nutzung davon
ATE503768T1 (de) Synthetische lungensurfactant peptide
ATE449790T1 (de) Rekombinante gelatinepartikel für die zelladhäsion
DE602007009797D1 (de) Antitumorheilmittel, Medikament, Zusammensetzung und Verwendung davon
UA93432C2 (ru) Модифицированный генно-инженерный рекомбинантный белок, который имитирует свойства поверхностного антигена cd34 человека