ATE544759T1 - 5-pyridinon-substituierte indazole und pharmazeutische zusammensetzungen davon - Google Patents
5-pyridinon-substituierte indazole und pharmazeutische zusammensetzungen davonInfo
- Publication number
- ATE544759T1 ATE544759T1 AT08796320T AT08796320T ATE544759T1 AT E544759 T1 ATE544759 T1 AT E544759T1 AT 08796320 T AT08796320 T AT 08796320T AT 08796320 T AT08796320 T AT 08796320T AT E544759 T1 ATE544759 T1 AT E544759T1
- Authority
- AT
- Austria
- Prior art keywords
- pyridinone
- pharmaceutical compositions
- substituted indazoles
- indazoles
- substituted
- Prior art date
Links
- 150000002473 indoazoles Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Chemical class 0.000 title 1
- ADEKJVNFIQUGRR-UHFFFAOYSA-N 4h-pyridin-3-one Chemical group O=C1CC=CN=C1 ADEKJVNFIQUGRR-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95120107P | 2007-07-21 | 2007-07-21 | |
| PCT/US2008/070535 WO2009015037A2 (en) | 2007-07-21 | 2008-07-18 | 5-pyridinone substituted indazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE544759T1 true ATE544759T1 (de) | 2012-02-15 |
Family
ID=40282093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08796320T ATE544759T1 (de) | 2007-07-21 | 2008-07-18 | 5-pyridinon-substituierte indazole und pharmazeutische zusammensetzungen davon |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8273770B2 (de) |
| EP (1) | EP2176251B1 (de) |
| JP (1) | JP2010534248A (de) |
| KR (1) | KR20100044225A (de) |
| CN (1) | CN101861311A (de) |
| AT (1) | ATE544759T1 (de) |
| AU (1) | AU2008279321B2 (de) |
| BR (1) | BRPI0814772A2 (de) |
| CA (1) | CA2693377A1 (de) |
| ES (1) | ES2382982T3 (de) |
| NZ (1) | NZ582586A (de) |
| WO (1) | WO2009015037A2 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008086404A1 (en) | 2007-01-10 | 2008-07-17 | Albany Molecular Research, Inc. | 5-pyridinone substituted indazoles |
| CN101861311A (zh) | 2007-07-21 | 2010-10-13 | 阿尔巴尼分子研究公司 | 5-吡啶酮取代的吲唑 |
| CA2727055C (en) | 2008-01-11 | 2016-12-20 | Albany Molecular Research, Inc. | (1-azinone) -substituted pyridoindoles as mch antagonists |
| WO2011003012A1 (en) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof |
| US8629158B2 (en) | 2009-07-01 | 2014-01-14 | Albany Molecular Research, Inc. | Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof |
| WO2011003005A1 (en) * | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine mch-1 antagonists, methods of making, and use thereof |
| WO2011003021A1 (en) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof |
| WO2012088124A2 (en) | 2010-12-21 | 2012-06-28 | Albany Molecular Research, Inc. | Tetrahydro-azacarboline mch-1 antagonists, methods of making, and uses thereof |
| US8697700B2 (en) | 2010-12-21 | 2014-04-15 | Albany Molecular Research, Inc. | Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof |
| US9730925B2 (en) | 2011-09-30 | 2017-08-15 | Glaxomithkline Llc | Methods of treating cancer |
| CN107011283A (zh) * | 2017-05-31 | 2017-08-04 | 湖南华腾制药有限公司 | 一种甲硫基取代苯并[d]恶唑衍生物的制备方法 |
| US11242334B2 (en) | 2017-08-22 | 2022-02-08 | Js Innopharm (Shanghai) Ltd. | Heterocyclic compounds as kinase inhibitors, compositions comprising the heterocyclic compound, and methods of use thereof |
| WO2020169058A1 (zh) * | 2019-02-21 | 2020-08-27 | 杭州阿诺生物医药科技有限公司 | Pd-l1拮抗剂化合物 |
Family Cites Families (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1A (en) | 1836-07-13 | John Ruggles | Locomotive steam-engine for rail and other roads | |
| US5225565A (en) | 1988-09-15 | 1993-07-06 | The Upjohn Company | Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones |
| US5182403A (en) | 1988-09-15 | 1993-01-26 | The Upjohn Company | Substituted 3(5'indazolyl) oxazolidin-2-ones |
| EP0460064A4 (en) | 1989-02-23 | 1992-04-01 | Rorer International (Holdings) Inc. | Therapeutic aerosol formulations |
| US5393735A (en) | 1990-08-09 | 1995-02-28 | Rohm And Haas Company | Herbicidal glutarimides |
| GB8921222D0 (en) | 1989-09-20 | 1989-11-08 | Riker Laboratories Inc | Medicinal aerosol formulations |
| JPH03253852A (ja) | 1990-03-05 | 1991-11-12 | Fuji Photo Film Co Ltd | ハロゲン化銀写真感光材料の処理方法及び最終処理組成物 |
| DE4017211A1 (de) | 1990-05-29 | 1991-12-05 | Merck Patent Gmbh | Oxazolidinone |
| DE4018830A1 (de) | 1990-06-12 | 1991-12-19 | Langhals Heinz | Synthese und verwendung von nicht-symmetrisch substituierten perylen-fluoreszenzfarbstoffen |
| US5230884A (en) | 1990-09-11 | 1993-07-27 | University Of Wales College Of Cardiff | Aerosol formulations including proteins and peptides solubilized in reverse micelles and process for making the aerosol formulations |
| US5292499A (en) | 1990-09-11 | 1994-03-08 | University Of Wales College Of Cardiff | Method of preparing medical aerosol formulations including drug dissolved in reverse micelles |
| US6632456B1 (en) | 1993-06-24 | 2003-10-14 | Astrazeneca Ab | Compositions for inhalation |
| TW279860B (de) | 1993-11-12 | 1996-07-01 | Ciba Geigy Ag | |
| DE4338784A1 (de) | 1993-11-12 | 1995-05-18 | Langhals Heinz | Perylen-3,4-dicarbonsäureimide - neue hoch lichtechte Fluoreszenzfarbstoffe |
| US6524557B1 (en) | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
| CH689139A5 (de) | 1995-04-03 | 1998-10-30 | Cerbios Pharma Sa | Verfahren zur Herstellung einer liposomalen, in Wasser dispergierbaren, oral zu verabreichenden, festen, trockenen therapeutischen Formulierung. |
| US6309671B1 (en) | 1995-04-14 | 2001-10-30 | Inhale Therapeutic Systems | Stable glassy state powder formulations |
| US5635161A (en) | 1995-06-07 | 1997-06-03 | Abbott Laboratories | Aerosol drug formulations containing vegetable oils |
| ZA966885B (en) | 1995-08-22 | 1998-02-16 | Du Pont Merck Pharma | Substituted cyclic ureas and derivatives thereof useful as retroviral protease inhibitors. |
| WO1997008150A1 (en) | 1995-08-22 | 1997-03-06 | The Du Pont Merck Pharmaceutical Company | Substituted cyclic ureas and derivatives thereof useful as retroviral protease inhibitors |
| US6120794A (en) | 1995-09-26 | 2000-09-19 | University Of Pittsburgh | Emulsion and micellar formulations for the delivery of biologically active substances to cells |
| WO1997012884A1 (en) | 1995-10-04 | 1997-04-10 | Fmc Corporation | Herbicidal 6-heterocyclic indazole derivatives |
| ATE243998T1 (de) | 1995-10-12 | 2003-07-15 | Supergen Inc | Liposomformulierung von 5-beta steroiden |
| US6107300A (en) | 1996-03-27 | 2000-08-22 | Dupont Pharmaceuticals | Arylamino fused pyrimidines |
| DE19651712A1 (de) | 1996-12-12 | 1998-06-18 | Langhals Heinz | Pyrrolo- und Thiophenoperylenimide - stark fluoreszierende Heterocylen |
| JP2002535242A (ja) | 1998-05-20 | 2002-10-22 | ザ リポソーム カンパニー、インコーポレーテッド | 新規な粒子状剤型 |
| US6451349B1 (en) | 1998-08-19 | 2002-09-17 | Quadrant Healthcare (Uk) Limited | Spray-drying process for the preparation of microparticles |
| GB9814172D0 (en) | 1998-06-30 | 1998-08-26 | Andaris Ltd | Formulation for inhalation |
| US6290987B1 (en) | 1998-09-27 | 2001-09-18 | Generex Pharmaceuticals, Inc. | Mixed liposome pharmaceutical formulation with amphiphiles and phospholipids |
| US6436367B1 (en) | 1998-12-21 | 2002-08-20 | Generex Pharmaceuticals Inc. | Aerosol formulations for buccal and pulmonary application |
| EP1338272A1 (de) | 1998-12-21 | 2003-08-27 | Generex Pharmaceuticals Inc. | Aerosol Formulierungen für buccale und pulmonale Anwendung enthaltend Chenodeoxycholate oder Deoxycholate |
| US6294153B1 (en) | 1998-12-21 | 2001-09-25 | Generex Pharmaceuticals, Inc. | Aerosol pharmaceutical formulation for pulmonary and nasal delivery |
| AU780397B2 (en) | 1999-02-03 | 2005-03-17 | Powderject Research Limited | Hydrogel particle formulations |
| CA2382821A1 (en) | 1999-08-25 | 2001-03-01 | Advanced Inhalation Research, Inc. | Modulation of release from dry powder formulations |
| US20010036481A1 (en) | 1999-08-25 | 2001-11-01 | Advanced Inhalation Research, Inc. | Modulation of release from dry powder formulations |
| BR0107764A (pt) | 2000-01-20 | 2002-11-12 | Basilea Pharmaceutica Ag | Composições de peptìdeo cìclico nasalmente administráveis |
| EP1129705A1 (de) | 2000-02-17 | 2001-09-05 | Rijksuniversiteit te Groningen | Pulverformulierung zur Inhalation |
| GB0009468D0 (en) | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formulations for use in inhaler devices |
| PE20011227A1 (es) | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros |
| JP2004500424A (ja) | 2000-04-17 | 2004-01-08 | ヴェクトゥラ リミテッド | 吸入器で使用するための製剤 |
| DE10104279A1 (de) | 2001-01-31 | 2002-08-01 | Heinz Langhals | Kompetitive Prionen-Reagenzien und ihre Anwendung in Diagnostik und Therapie |
| GB0107106D0 (en) | 2001-03-21 | 2001-05-09 | Boehringer Ingelheim Pharma | Powder inhaler formulations |
| WO2002092090A1 (en) | 2001-05-14 | 2002-11-21 | Bristol-Myers Squibb Pharma Company | Substituted pyrazinones, pyridines and pyrimidines as corticotropin releasing factor ligands |
| US20030114448A1 (en) | 2001-05-31 | 2003-06-19 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
| US20030019437A1 (en) | 2001-07-26 | 2003-01-30 | John Fore | Ungulate game animal feed system and method |
| US20030064033A1 (en) | 2001-08-16 | 2003-04-03 | Brown Larry R. | Propellant-based microparticle formulations |
| AU2002326948A1 (en) | 2001-09-18 | 2003-04-01 | Bristol-Myers Squibb Company | Piperizinones as modulators of chemokine receptor activity |
| GB0124627D0 (en) | 2001-10-15 | 2001-12-05 | Smithkline Beecham Plc | Novel compounds |
| TW200302225A (en) | 2001-12-04 | 2003-08-01 | Bristol Myers Squibb Co | Substituted amino methyl factor Xa inhibitors |
| WO2003072080A1 (en) | 2002-02-22 | 2003-09-04 | Advanced Inhalation Research, Inc. | Inhalable formulations for sustained release |
| CA2478974C (en) | 2002-03-20 | 2014-12-16 | Advanced Inhalation Research, Inc. | Inhalable sustained therapeutic formulations |
| DE60307082D1 (de) | 2002-05-07 | 2006-09-07 | Ferring Bv | In der mundhöhle dispergierbare phamarzeutische zusammensetzung mit desmopressin |
| PL376156A1 (en) | 2002-10-04 | 2005-12-27 | Millennium Pharmaceuticals, Inc. | Pgd2 receptor antagonists for the treatment of inflammatory diseases |
| US20060194871A1 (en) | 2003-04-11 | 2006-08-31 | Barvian Kevin K | Heterocyclic mchr1 antagoists |
| US7560467B2 (en) | 2003-06-19 | 2009-07-14 | Smithkline Beecham Corporation | Indazolo-tetrahydropyrimidine-carboxamide derivative kinase inhibitors |
| CL2004002050A1 (es) * | 2003-08-13 | 2005-06-03 | Pharmacia Corp Sa Organizada B | Compuestos derivados de piridinonas sustituidas; su uso en el tratamiento de afecciones causadas o exacerbadas por actividad p38 map kinasa y/o tnf no regulada, tales como inflamaciones, tumores, sida y otros. |
| US7390820B2 (en) | 2003-08-25 | 2008-06-24 | Amgen Inc. | Substituted quinolinone derivatives and methods of use |
| US7320992B2 (en) | 2003-08-25 | 2008-01-22 | Amgen Inc. | Substituted 2,3-dihydro-1h-isoindol-1-one derivatives and methods of use |
| JP2007509158A (ja) | 2003-10-23 | 2007-04-12 | グラクソ グループ リミテッド | 肥満、糖尿病、うつ病及び不安を治療するためのｍｃｈｒ１アンタゴニストとしての３−（４−アミノフェニル）チエノピリミド−４−オン誘導体 |
| US20050137243A1 (en) | 2003-12-23 | 2005-06-23 | Souers Andrew J. | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor |
| US7049307B2 (en) | 2003-12-23 | 2006-05-23 | Abbott Laboratories | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor |
| US7071182B2 (en) | 2003-12-23 | 2006-07-04 | Abbott Laboratories | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor |
| US7732456B2 (en) * | 2004-03-05 | 2010-06-08 | Banyu Pharmaceutical Co., Ltd. | Pyridone derivative |
| RU2386633C2 (ru) | 2004-05-07 | 2010-04-20 | Мемори Фармасьютиклз Корпорейшн | 1h-индазолы, бензотиазолы, 1, 2-бензоизоксазолы, 1, 2-бензоизотиазолы и хромоны и их получение и применения |
| WO2006017257A2 (en) | 2004-07-12 | 2006-02-16 | Phenomix Corporation | Azetidinone derivatives |
| WO2007029847A1 (ja) * | 2005-09-07 | 2007-03-15 | Banyu Pharmaceutical Co., Ltd. | 二環性芳香族置換ピリドン誘導体 |
| WO2008086404A1 (en) * | 2007-01-10 | 2008-07-17 | Albany Molecular Research, Inc. | 5-pyridinone substituted indazoles |
| MX2009007336A (es) * | 2007-01-10 | 2009-07-15 | Albany Molecular Res Inc | Indazoles substituidos con 5-furopiridinona. |
| CN101861311A (zh) | 2007-07-21 | 2010-10-13 | 阿尔巴尼分子研究公司 | 5-吡啶酮取代的吲唑 |
-
2008
- 2008-07-18 CN CN200880107571A patent/CN101861311A/zh active Pending
- 2008-07-18 NZ NZ582586A patent/NZ582586A/en not_active IP Right Cessation
- 2008-07-18 AU AU2008279321A patent/AU2008279321B2/en not_active Ceased
- 2008-07-18 KR KR1020107003768A patent/KR20100044225A/ko not_active Withdrawn
- 2008-07-18 JP JP2010518311A patent/JP2010534248A/ja active Pending
- 2008-07-18 ES ES08796320T patent/ES2382982T3/es active Active
- 2008-07-18 EP EP08796320A patent/EP2176251B1/de not_active Not-in-force
- 2008-07-18 WO PCT/US2008/070535 patent/WO2009015037A2/en not_active Ceased
- 2008-07-18 BR BRPI0814772-8A2A patent/BRPI0814772A2/pt not_active IP Right Cessation
- 2008-07-18 AT AT08796320T patent/ATE544759T1/de active
- 2008-07-18 US US12/176,144 patent/US8273770B2/en not_active Expired - Fee Related
- 2008-07-18 CA CA2693377A patent/CA2693377A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008279321B2 (en) | 2013-08-01 |
| BRPI0814772A2 (pt) | 2015-03-03 |
| WO2009015037A2 (en) | 2009-01-29 |
| AU2008279321A1 (en) | 2009-01-29 |
| KR20100044225A (ko) | 2010-04-29 |
| ES2382982T3 (es) | 2012-06-15 |
| US20090082359A1 (en) | 2009-03-26 |
| US8273770B2 (en) | 2012-09-25 |
| CN101861311A (zh) | 2010-10-13 |
| EP2176251B1 (de) | 2012-02-08 |
| HK1142608A1 (en) | 2010-12-10 |
| CA2693377A1 (en) | 2009-01-29 |
| WO2009015037A3 (en) | 2009-04-30 |
| JP2010534248A (ja) | 2010-11-04 |
| NZ582586A (en) | 2011-12-22 |
| EP2176251A2 (de) | 2010-04-21 |
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