ATE544869T1 - Verfahren und substanzen zur isolierung und erkennung kleiner polynukleotide - Google Patents
Verfahren und substanzen zur isolierung und erkennung kleiner polynukleotideInfo
- Publication number
- ATE544869T1 ATE544869T1 AT07841673T AT07841673T ATE544869T1 AT E544869 T1 ATE544869 T1 AT E544869T1 AT 07841673 T AT07841673 T AT 07841673T AT 07841673 T AT07841673 T AT 07841673T AT E544869 T1 ATE544869 T1 AT E544869T1
- Authority
- AT
- Austria
- Prior art keywords
- small
- isolation
- substances
- detection
- small polynucleotide
- Prior art date
Links
- 102000040430 polynucleotide Human genes 0.000 title abstract 6
- 108091033319 polynucleotide Proteins 0.000 title abstract 6
- 239000002157 polynucleotide Substances 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 4
- 238000002955 isolation Methods 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
- 239000000523 sample Substances 0.000 abstract 4
- 230000003321 amplification Effects 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 230000009977 dual effect Effects 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82406806P | 2006-08-30 | 2006-08-30 | |
| US82588806P | 2006-09-15 | 2006-09-15 | |
| US86388606P | 2006-11-01 | 2006-11-01 | |
| US86621006P | 2006-11-16 | 2006-11-16 | |
| US87109406P | 2006-12-20 | 2006-12-20 | |
| PCT/US2007/077311 WO2008028086A2 (en) | 2006-08-30 | 2007-08-30 | Methods and substances for isolation and detection of small polynucleotides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE544869T1 true ATE544869T1 (de) | 2012-02-15 |
Family
ID=39136920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07841673T ATE544869T1 (de) | 2006-08-30 | 2007-08-30 | Verfahren und substanzen zur isolierung und erkennung kleiner polynukleotide |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8329394B2 (de) |
| EP (1) | EP2057181B1 (de) |
| CN (1) | CN101528763B (de) |
| AT (1) | ATE544869T1 (de) |
| CA (1) | CA2662837C (de) |
| WO (1) | WO2008028086A2 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2445204C (en) | 2002-10-16 | 2014-08-12 | Streck Laboratories, Inc. | Method and device for collecting and preserving cells for analysis |
| WO2007024653A2 (en) * | 2005-08-19 | 2007-03-01 | Bioventures, Inc. | Method and substances for isolating micro rnas |
| US20110172105A1 (en) * | 2008-06-04 | 2011-07-14 | Salk Institute For Biological Studies | GREPSEQ: An Almost Inexhaustible, Cost-Effective, High-Throughput Protocol for the Generation of Selector Sequences |
| US11634747B2 (en) | 2009-01-21 | 2023-04-25 | Streck Llc | Preservation of fetal nucleic acids in maternal plasma |
| NO2398912T3 (de) | 2009-02-18 | 2018-02-10 | ||
| US20130296189A1 (en) * | 2009-05-08 | 2013-11-07 | Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences | Probes utilizing universal tags, a kit comprising the same and detection methods |
| US20110111410A1 (en) * | 2009-11-09 | 2011-05-12 | Streck, Inc. | Stabilization of rna in intact cells within a blood sample |
| US9956281B2 (en) | 2011-05-04 | 2018-05-01 | Streck, Inc. | Inactivated virus compositions and methods of preparing such compositions |
| CA2841941C (en) * | 2011-07-15 | 2019-08-20 | Orasure Technologies, Inc. | Sample collection kit |
| GB2493141A (en) * | 2011-07-19 | 2013-01-30 | Gene Onyx Ltd | Method of selecting a product using a DNA sample |
| US10091984B2 (en) | 2013-07-24 | 2018-10-09 | Streck, Inc. | Compositions and methods for stabilizing circulating tumor cells |
| CN103484544B (zh) * | 2013-09-17 | 2015-11-25 | 遵义医学院 | 一种微小rna启动子活性检测的方法 |
| CN105274194A (zh) * | 2014-12-10 | 2016-01-27 | 临沂大学 | 一种基于多重放大技术的肿瘤标志物let7a检测方法 |
| US11168351B2 (en) | 2015-03-05 | 2021-11-09 | Streck, Inc. | Stabilization of nucleic acids in urine |
| US20170145475A1 (en) | 2015-11-20 | 2017-05-25 | Streck, Inc. | Single spin process for blood plasma separation and plasma composition including preservative |
| WO2017096322A1 (en) * | 2015-12-03 | 2017-06-08 | Accuragen Holdings Limited | Methods and compositions for forming ligation products |
| ES2898088T3 (es) | 2016-06-01 | 2022-03-03 | Hoffmann La Roche | Inmuno-PETE |
| WO2018022991A1 (en) | 2016-07-29 | 2018-02-01 | Streck, Inc. | Suspension composition for hematology analysis control |
| GB201701262D0 (en) * | 2017-01-25 | 2017-03-08 | Sense Biodetection Ltd | Nucleic acid detection method |
| CN115119829B (zh) | 2017-10-19 | 2024-07-12 | 斯特雷克股份有限公司 | 用于胞外囊泡的溶血和凝血调节以及稳定化的组合物 |
| WO2019121842A1 (en) * | 2017-12-21 | 2019-06-27 | F. Hoffmann-La Roche Ag | Target enrichment by unidirectional dual probe primer extension |
| US11993806B2 (en) * | 2018-09-11 | 2024-05-28 | Sekisui Medical Co., Ltd. | Method of detecting or method of quantifying oligonucleotides |
| CN110358810B (zh) * | 2019-07-29 | 2023-06-23 | 江苏省原子医学研究所 | 一种检测miRNA的生物探针及检测方法和用途 |
| CN113088560B (zh) * | 2021-04-16 | 2022-02-25 | 杭州德同生物技术有限公司 | 基于杂交捕获及酶保护的microRNA高通量检测方法及试剂盒 |
| WO2023129887A1 (en) * | 2021-12-29 | 2023-07-06 | Co-Diagnostics, Inc. | Methods and systems for analyzing nucleic acids using increased ifret with multiple acceptor fluorophores |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5629153A (en) * | 1990-01-10 | 1997-05-13 | Chiron Corporation | Use of DNA-dependent RNA polymerase transcripts as reporter molecules for signal amplification in nucleic acid hybridization assays |
| AU6088094A (en) * | 1993-01-15 | 1994-08-15 | General Hospital Corporation, The | Rna assays using rna binary probes and ribozyme ligase |
| US6045802A (en) * | 1994-10-03 | 2000-04-04 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Enhanced immune response to an antigen by a composition of a recombinant virus expressing the antigen with a recombinant virus expressing an immunostimulatory molecule |
| US5750341A (en) * | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
| US6251433B1 (en) * | 1996-08-13 | 2001-06-26 | Chiron Corporation | Polycationic polymers |
| US7101672B2 (en) * | 1998-05-05 | 2006-09-05 | Third Wave Technologies, Inc. | Target-dependent reactions using structure-bridging oligonucleotides |
| US6365731B1 (en) | 1997-08-06 | 2002-04-02 | Ambion, Inc. | Stripping nucleic acids with iodine and sodium thiosulfate |
| EP1019429A4 (de) * | 1997-08-20 | 2001-08-08 | Somagenics Inc | Antisense- und antigen-therapeutika mit verbesserten bindungseigenschaften und methoden zu ihrer anwendung |
| AU1603199A (en) * | 1997-12-03 | 1999-06-16 | Curagen Corporation | Methods and devices for measuring differential gene expression |
| US6391551B1 (en) * | 1998-03-13 | 2002-05-21 | Promega Corporation | Detection of nucleic acid hybrids |
| DK2070939T3 (da) * | 2001-05-25 | 2014-06-23 | Univ Duke | Modulatorer af farmakologiske midler |
| US8192937B2 (en) * | 2004-04-07 | 2012-06-05 | Exiqon A/S | Methods for quantification of microRNAs and small interfering RNAs |
| WO2006033020A2 (en) | 2004-04-26 | 2006-03-30 | Rosetta Genomics Ltd. | Methods and apparatus for the detection and validation of micrornas |
| WO2007024653A2 (en) * | 2005-08-19 | 2007-03-01 | Bioventures, Inc. | Method and substances for isolating micro rnas |
| WO2007035684A2 (en) * | 2005-09-16 | 2007-03-29 | Primera Biosystems, Inc. | Method for quantitative detection of short rna molecules |
-
2007
- 2007-08-30 WO PCT/US2007/077311 patent/WO2008028086A2/en not_active Ceased
- 2007-08-30 AT AT07841673T patent/ATE544869T1/de active
- 2007-08-30 EP EP07841673A patent/EP2057181B1/de active Active
- 2007-08-30 CA CA2662837A patent/CA2662837C/en active Active
- 2007-08-30 CN CN2007800319763A patent/CN101528763B/zh not_active Expired - Fee Related
- 2007-12-17 US US11/958,180 patent/US8329394B2/en active Active
-
2012
- 2012-11-15 US US13/678,368 patent/US20130116154A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2662837A1 (en) | 2008-03-06 |
| WO2008028086A3 (en) | 2008-11-13 |
| CN101528763B (zh) | 2012-06-27 |
| EP2057181A2 (de) | 2009-05-13 |
| US20080102470A1 (en) | 2008-05-01 |
| EP2057181A4 (de) | 2009-12-02 |
| WO2008028086A9 (en) | 2009-04-02 |
| EP2057181B1 (de) | 2012-02-08 |
| WO2008028086A2 (en) | 2008-03-06 |
| CN101528763A (zh) | 2009-09-09 |
| US20130116154A1 (en) | 2013-05-09 |
| CA2662837C (en) | 2012-07-31 |
| US8329394B2 (en) | 2012-12-11 |
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