ATE547518T1 - Verfahren zur sammlung von kristallinen partikeln aus fermentationsbrühe - Google Patents
Verfahren zur sammlung von kristallinen partikeln aus fermentationsbrüheInfo
- Publication number
- ATE547518T1 ATE547518T1 AT02781173T AT02781173T ATE547518T1 AT E547518 T1 ATE547518 T1 AT E547518T1 AT 02781173 T AT02781173 T AT 02781173T AT 02781173 T AT02781173 T AT 02781173T AT E547518 T1 ATE547518 T1 AT E547518T1
- Authority
- AT
- Austria
- Prior art keywords
- fermentation broth
- crystalline particles
- collecting crystalline
- collecting
- crystalline
- Prior art date
Links
- 238000000855 fermentation Methods 0.000 title abstract 5
- 230000004151 fermentation Effects 0.000 title abstract 5
- 238000000034 method Methods 0.000 title 1
- 239000002245 particle Substances 0.000 title 1
- 239000002207 metabolite Substances 0.000 abstract 2
- 239000000725 suspension Substances 0.000 abstract 2
- 239000002028 Biomass Substances 0.000 abstract 1
- 239000000701 coagulant Substances 0.000 abstract 1
- 239000008394 flocculating agent Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2414—Alpha-amylase (3.2.1.1.)
- C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
- C07K1/306—Extraction; Separation; Purification by precipitation by crystallization
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Mushroom Cultivation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200101847 | 2001-12-11 | ||
| PCT/DK2002/000821 WO2003050274A2 (en) | 2001-12-11 | 2002-12-04 | Process for harvesting crystalline particles from fermentation broth |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE547518T1 true ATE547518T1 (de) | 2012-03-15 |
Family
ID=8160891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02781173T ATE547518T1 (de) | 2001-12-11 | 2002-12-04 | Verfahren zur sammlung von kristallinen partikeln aus fermentationsbrühe |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1456361B1 (de) |
| CN (1) | CN100487114C (de) |
| AT (1) | ATE547518T1 (de) |
| AU (1) | AU2002349300A1 (de) |
| DK (1) | DK1456361T3 (de) |
| WO (1) | WO2003050274A2 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050176090A1 (en) * | 2003-10-31 | 2005-08-11 | Novozymes A/S | Method for flocculation of a fermentation broth comprising a fungus |
| JP2007535911A (ja) * | 2003-12-30 | 2007-12-13 | バハラ バイオテック インターナショナル リミテッド | 組換えタンパク質の製造及び精製方法 |
| CN101679482A (zh) * | 2006-12-22 | 2010-03-24 | 塔利克里斯生物治疗公司 | 用于沉淀肽的装置和方法 |
| DE102008029401A1 (de) * | 2008-06-23 | 2009-12-24 | Bayer Technology Services Gmbh | Verfahren zur Kristallisation von Peptiden und Proteinen |
| EP2196539B1 (de) * | 2008-12-15 | 2022-02-09 | Delft Advanced Biofuels B.V. | Verfahren zur kontinuierlichen biologischen Herstellung von Lipiden, Kohlenwasserstoffen oder Zusammensetzungen davon |
| DK2552934T3 (en) * | 2010-03-30 | 2015-09-28 | Novozymes As | Krystalmetabolit-extraction |
| CN102838552B (zh) * | 2012-09-21 | 2015-08-05 | 江南大学 | 采用复合絮凝法生产高纯度吩嗪-1-羧酸的方法 |
| EP2914611B1 (de) | 2012-11-01 | 2018-08-29 | Novozymes A/S | Verfahren zum entfernen von dna |
| CN106146610B (zh) * | 2016-09-22 | 2018-01-23 | 济南大学 | 一种采用絮凝法制备谷胱甘肽亚铜盐的方法 |
| EP3606936B1 (de) * | 2017-04-03 | 2021-10-20 | Novozymes A/S | Verfahren zur rückgewinnung |
| WO2019160862A1 (en) * | 2018-02-13 | 2019-08-22 | Lygos, Inc. | Method for preparation of diester derivatives of malonic acid |
| US20210380667A1 (en) | 2018-10-10 | 2021-12-09 | Novozymes A/S | Chymotrypsin Inhibitor Variants And The Use Thereof |
| AU2020340444A1 (en) | 2019-08-30 | 2022-04-14 | Lygos, Inc. | Recombinant host cells for the production of malonate |
| CA3205833A1 (en) | 2021-02-08 | 2022-08-11 | Arla Foods Amba | Crystallisation of beta-lactoglobulin using multiple protein feeds |
| EP4568983A1 (de) * | 2022-08-10 | 2025-06-18 | Arla Foods amba | Kristallisierung eines proteins, das unter einsalzungsbedingungen kristallisieren kann, unter verwendung mehrerer protein-feeds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4659667A (en) * | 1985-02-26 | 1987-04-21 | Miles Laboratories, Inc. | Process to recover crystalline enzymes and crystalline enzymes produced thereby |
| JP2958789B2 (ja) * | 1990-01-22 | 1999-10-06 | 味の素株式会社 | アミノ酸・核酸およびその誘導体の精製方法 |
| EP0574050A1 (de) * | 1992-05-19 | 1993-12-15 | Gist-Brocades N.V. | Trennung und Reinigung von Fermentationsprodukt in grossen Massstab |
| DK83093D0 (da) * | 1993-07-09 | 1993-07-09 | Novo Nordisk As | Fremgangsmaade |
| EP0828753B1 (de) * | 1995-06-02 | 2003-03-26 | Novozymes A/S | BEHANDLUNG EINER PROTEINLÖSUNG MIT A1/Fe UND ANSCHLIESENDE MEMBRANKONZENTRATION |
-
2002
- 2002-12-04 AT AT02781173T patent/ATE547518T1/de active
- 2002-12-04 AU AU2002349300A patent/AU2002349300A1/en not_active Abandoned
- 2002-12-04 WO PCT/DK2002/000821 patent/WO2003050274A2/en not_active Ceased
- 2002-12-04 DK DK02781173.6T patent/DK1456361T3/da active
- 2002-12-04 EP EP02781173A patent/EP1456361B1/de not_active Expired - Lifetime
- 2002-12-04 CN CNB028243110A patent/CN100487114C/zh not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003050274A3 (en) | 2003-12-11 |
| WO2003050274A2 (en) | 2003-06-19 |
| AU2002349300A1 (en) | 2003-06-23 |
| EP1456361A2 (de) | 2004-09-15 |
| DK1456361T3 (da) | 2012-06-11 |
| CN1599795A (zh) | 2005-03-23 |
| CN100487114C (zh) | 2009-05-13 |
| EP1456361B1 (de) | 2012-02-29 |
| AU2002349300A8 (en) | 2003-06-23 |
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