ATE547523T1 - Vegfr-varianten und deren verwendung bei der diagnose und behandlung von mit schwangerschaft assoziierten medizinischen leiden - Google Patents

Vegfr-varianten und deren verwendung bei der diagnose und behandlung von mit schwangerschaft assoziierten medizinischen leiden

Info

Publication number
ATE547523T1
ATE547523T1 AT07849615T AT07849615T ATE547523T1 AT E547523 T1 ATE547523 T1 AT E547523T1 AT 07849615 T AT07849615 T AT 07849615T AT 07849615 T AT07849615 T AT 07849615T AT E547523 T1 ATE547523 T1 AT E547523T1
Authority
AT
Austria
Prior art keywords
pregnancy
diagnosis
treatment
conditions associated
medical conditions
Prior art date
Application number
AT07849615T
Other languages
English (en)
Inventor
Eli Keshet
Shay Sela
Ahuva Itin
Simcha Yagel
Original Assignee
Yissum Res Dev Co
Hadasit Med Res Service
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co, Hadasit Med Res Service filed Critical Yissum Res Dev Co
Application granted granted Critical
Publication of ATE547523T1 publication Critical patent/ATE547523T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pregnancy & Childbirth (AREA)
AT07849615T 2006-12-20 2007-12-20 Vegfr-varianten und deren verwendung bei der diagnose und behandlung von mit schwangerschaft assoziierten medizinischen leiden ATE547523T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87582206P 2006-12-20 2006-12-20
PCT/IL2007/001589 WO2008075363A1 (en) 2006-12-20 2007-12-20 Variants of vegfr and their use in the diagnosis and treatment of pregnancy associated medical conditions

Publications (1)

Publication Number Publication Date
ATE547523T1 true ATE547523T1 (de) 2012-03-15

Family

ID=39271517

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07849615T ATE547523T1 (de) 2006-12-20 2007-12-20 Vegfr-varianten und deren verwendung bei der diagnose und behandlung von mit schwangerschaft assoziierten medizinischen leiden

Country Status (6)

Country Link
US (3) US20100136012A1 (de)
EP (1) EP2099913B1 (de)
JP (1) JP2010512781A (de)
AT (1) ATE547523T1 (de)
CA (1) CA2673222A1 (de)
WO (1) WO2008075363A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100136012A1 (en) 2006-12-20 2010-06-03 Hadasit Medical Research Services And Development Ltd. Variants of vegfr and their use in the diagnosis and treatment of pregnancy associated medical conditions
WO2010106997A1 (ja) * 2009-03-19 2010-09-23 株式会社カネカ 核酸の検出方法及びキット、デバイス
WO2011013131A1 (en) 2009-07-29 2011-02-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Polynucleotides and constructs encoding sflt1-14 and method for efficient propagation and expression thereof
US20160024181A1 (en) 2013-03-13 2016-01-28 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules
RU2670747C1 (ru) * 2017-10-19 2018-10-25 Федеральное государственное бюджетное образовательное учреждение высшего образования "Российский национальный исследовательский медицинский университет им. Н.И. Пирогова" Министерства здравоохранения Российской Федерации (ФГБОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России) Способ определения показаний для срочного родоразрешения при преэклампсии
FR3081707A1 (fr) * 2018-05-30 2019-12-06 Universite De Rouen Normandie Traitement des troubles neurologiques causes par l'alcoolisation foetale
US20220135651A1 (en) * 2019-02-18 2022-05-05 Agency For Science, Technology And Research A membrane-bound fit-1 decoy and uses thereof
EP4070113A4 (de) 2019-12-04 2023-12-20 Biora Therapeutics, Inc. Beurteilung von präeklampsie unter verwendung von tests für freien und dissoziierten plazentalen wachstumsfaktor

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6710174B2 (en) * 2001-09-13 2004-03-23 Isis Pharmaceuticals, Inc. Antisense inhibition of vascular endothelial growth factor receptor-1 expression
WO2001064835A2 (en) * 2000-02-28 2001-09-07 Hyseq, Inc. Novel nucleic acids and polypeptides
US20040216828A1 (en) * 2001-08-17 2004-11-04 Ortega Albert E. Nonwoven fabrics with two or more filament cross sections
BRPI0312818B8 (pt) * 2002-07-19 2021-05-25 Beth Israel Deaconess Medical Ct Inc uso de uma medida do nível do polipeptídeo sflt-1 em uma amostra de uma paciente e uso de uma medida dos níveis de pelo menos dois dos peptídeos sflt1, vegf livre ou polipeptídio pigf livre em uma amostra de um paciente usando um métrico
WO2005072340A2 (en) * 2004-01-27 2005-08-11 Compugen Ltd. Novel polynucleotides encoding polypeptides and methods using same
WO2006033664A1 (en) 2004-03-08 2006-03-30 Avalon Pharmaceuticals Determining cancer-linked genes and therapeutic targets using molecular cytogenetic methods
ATE519109T1 (de) * 2004-12-21 2011-08-15 Univ Yale Präeklampsie-diagnose
IL172297A (en) * 2005-10-03 2016-03-31 Compugen Ltd Soluble vegfr-1 variants for diagnosis of preeclamsia
US20100136012A1 (en) 2006-12-20 2010-06-03 Hadasit Medical Research Services And Development Ltd. Variants of vegfr and their use in the diagnosis and treatment of pregnancy associated medical conditions

Also Published As

Publication number Publication date
EP2099913A1 (de) 2009-09-16
WO2008075363A1 (en) 2008-06-26
US20140295454A1 (en) 2014-10-02
JP2010512781A (ja) 2010-04-30
CA2673222A1 (en) 2008-06-26
US20100136012A1 (en) 2010-06-03
EP2099913B1 (de) 2012-02-29
US9797911B2 (en) 2017-10-24
US20130084583A1 (en) 2013-04-04

Similar Documents

Publication Publication Date Title
AR064642A1 (es) Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
DE69922261D1 (de) Monoklonale antikörper, antigene sowie diagnose und therapie von bösartigen krankheiten
DE60327786D1 (de) Kdr-peptide und diese enthaltende impfstoffe
CA2438080A1 (en) Gonococcal proteins and nucleic acids
RU2011108943A (ru) Профилактика, лечение и диагностика инфекции, вызванной бактериями p.gingivalis
MX2008009886A (es) Anticuerpos que enlazan par-2.
EP2730659A3 (de) Behandlung und Prophylaxe von Amyloidose
EP1498424A3 (de) Humane Nukleinsäuresequenzen aus Bronchialkarzinomen
EA201270517A1 (ru) Микобактериальные вакцины
EP2292646A3 (de) Kleine Streptococcus-pyogenes-Antigene und Verwendung dafür
MX345316B (es) Métodos y composiciones para diagnóstico y tratamiento del cáncer.
CY1108568T1 (el) Αναστολεας για διαγνωση και θεραπεια ασθενων με αιμορροφιλια α
MXPA05011085A (es) Composiciones y metodos relacionados a stop-1.
NO20081453L (no) Sammensetninger og fremgangsmater for diagnostisering og behandling av inflammasjon
EA200700951A1 (ru) БЕЛКИ, СОДЕРЖАЩИЕ ДОМЕНЫ vWFA И/ИЛИ ANT_IG
ATE533776T1 (de) Analoge verbindungen analgetischer peptide, abgeleitet vom crotalus durissus terrificus schlangengift, ihre verwendungen, zusammensetzungen und verfahren ihrer herstellung und reinigung
ATE334145T1 (de) Neues menschliches ulip/crmp protein und seine verwendung zur diagnose zur behandlung von krebs und von neurologischen paraneoplastischen syndromen
JP2011509080A5 (de)
DE602006004966D1 (de) Intrinsic-faktor vom schwein
DE60035857D1 (de) Nukleinsäure- und aminosäuresequenzen von durch hämoglobin induzierbaren genen aus candida albicans und die verwendung dieser sequenzen in reagenzien zur diagnose von disseminierten candida albicans infektionen
JP2020505060A (ja) 腫瘍壊死因子αの高親和性ペプチド及びその適用
DE602005018369D1 (de) Neue proteine, z.b. zur verwendung für die in-vitro-isolierung und prävention von legionella pneumophila-infektionen
ATE512983T1 (de) Rezeptor für das tgr3-like protein
WO2007049065A3 (en) Vwfa, collagen and kunitz domain containing protein
ATE557035T1 (de) Identifizierung und charakterisierung eines neuartigen aviären pathogenen e. coli (apec) fimbrien-adhäsins