ATE547535T1 - Nukleosidpolyphosphate mit blockiertem terminalem phosphat - Google Patents
Nukleosidpolyphosphate mit blockiertem terminalem phosphatInfo
- Publication number
- ATE547535T1 ATE547535T1 AT03791982T AT03791982T ATE547535T1 AT E547535 T1 ATE547535 T1 AT E547535T1 AT 03791982 T AT03791982 T AT 03791982T AT 03791982 T AT03791982 T AT 03791982T AT E547535 T1 ATE547535 T1 AT E547535T1
- Authority
- AT
- Austria
- Prior art keywords
- terminal phosphate
- nucleoside polyphosphates
- nucleic acid
- blocked terminal
- blocked nucleoside
- Prior art date
Links
- 229910019142 PO4 Inorganic materials 0.000 title abstract 3
- 239000002777 nucleoside Substances 0.000 title abstract 3
- 150000003833 nucleoside derivatives Chemical class 0.000 title abstract 3
- 239000010452 phosphate Substances 0.000 title abstract 3
- 239000001205 polyphosphate Substances 0.000 title abstract 3
- 235000011176 polyphosphates Nutrition 0.000 title abstract 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical group [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 title 1
- 229920000388 Polyphosphate Polymers 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 abstract 2
- 230000003321 amplification Effects 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000010348 incorporation Methods 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 238000012163 sequencing technique Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40689202P | 2002-08-29 | 2002-08-29 | |
| PCT/US2003/027284 WO2004020602A2 (en) | 2002-08-29 | 2003-08-29 | Terminal phosphate blocked nucleoside polyphosphates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE547535T1 true ATE547535T1 (de) | 2012-03-15 |
Family
ID=31978377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03791982T ATE547535T1 (de) | 2002-08-29 | 2003-08-29 | Nukleosidpolyphosphate mit blockiertem terminalem phosphat |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1546399B1 (de) |
| JP (1) | JP4510628B2 (de) |
| AT (1) | ATE547535T1 (de) |
| AU (1) | AU2003263023B2 (de) |
| CA (1) | CA2496182C (de) |
| WO (1) | WO2004020602A2 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090162863A1 (en) * | 2007-12-13 | 2009-06-25 | Hitachi High-Technologies Corporation | Nucleic acid detection probe |
| US9523084B2 (en) | 2012-11-08 | 2016-12-20 | Centre National De La Recherche Scientifique (Cnrs) | Phosphodeoxyribosyl transferase mutant enzymes and uses thereof |
| JP6339787B2 (ja) * | 2013-10-09 | 2018-06-06 | 株式会社日立ハイテクノロジーズ | 核酸の分析方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4711955A (en) * | 1981-04-17 | 1987-12-08 | Yale University | Modified nucleotides and methods of preparing and using same |
| US4828979A (en) * | 1984-11-08 | 1989-05-09 | Life Technologies, Inc. | Nucleotide analogs for nucleic acid labeling and detection |
| JP4638043B2 (ja) * | 1998-12-14 | 2011-02-23 | パシフィック バイオサイエンシーズ オブ カリフォルニア， インコーポレイテッド | ポリメラーゼ合成による、単一分子の核酸の配列決定のためのシステムおよび方法 |
| US6323186B1 (en) * | 1999-09-17 | 2001-11-27 | Molecular Probes, Inc. | Phosphate-bound polyazaindacene derivatives of nucleotides |
| US6399335B1 (en) * | 1999-11-16 | 2002-06-04 | Advanced Research And Technology Institute, Inc. | γ-phosphoester nucleoside triphosphates |
| AU2001268291A1 (en) * | 2000-06-07 | 2001-12-17 | Li-Cor, Inc. | Charge-switch nucleotides |
| ATE377093T1 (de) * | 2000-07-07 | 2007-11-15 | Visigen Biotechnologies Inc | Sequenzbestimmung in echtzeit |
| US7211414B2 (en) * | 2000-12-01 | 2007-05-01 | Visigen Biotechnologies, Inc. | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity |
| US7041812B2 (en) * | 2001-08-29 | 2006-05-09 | Amersham Biosciences Corp | Labeled nucleoside polyphosphates |
| US7052839B2 (en) * | 2001-08-29 | 2006-05-30 | Amersham Biosciences Corp | Terminal-phosphate-labeled nucleotides and methods of use |
| US7033762B2 (en) * | 2001-08-29 | 2006-04-25 | Amersham Biosciences Corp | Single nucleotide amplification and detection by polymerase |
-
2003
- 2003-08-29 AT AT03791982T patent/ATE547535T1/de active
- 2003-08-29 AU AU2003263023A patent/AU2003263023B2/en not_active Expired
- 2003-08-29 JP JP2004532001A patent/JP4510628B2/ja not_active Expired - Lifetime
- 2003-08-29 WO PCT/US2003/027284 patent/WO2004020602A2/en not_active Ceased
- 2003-08-29 EP EP03791982A patent/EP1546399B1/de not_active Expired - Lifetime
- 2003-08-29 CA CA2496182A patent/CA2496182C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005536999A (ja) | 2005-12-08 |
| JP4510628B2 (ja) | 2010-07-28 |
| EP1546399A2 (de) | 2005-06-29 |
| AU2003263023A1 (en) | 2004-03-19 |
| WO2004020602A3 (en) | 2004-05-13 |
| EP1546399A4 (de) | 2007-07-25 |
| AU2003263023B2 (en) | 2008-09-11 |
| CA2496182C (en) | 2012-06-05 |
| WO2004020602A2 (en) | 2004-03-11 |
| EP1546399B1 (de) | 2012-02-29 |
| CA2496182A1 (en) | 2004-03-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Buschbeck et al. | Variants of core histones and their roles in cell fate decisions, development and cancer | |
| Sugden et al. | Direct oxidation of guanine and 7, 8-dihydro-8-oxoguanine in DNA by a high-valent chromium complex: a possible mechanism for chromate genotoxicity | |
| WO2003093469A3 (en) | Methods for delivering nucleic acid molecules into cells and assessment thereof | |
| WO2004063362A3 (en) | Cell cycle progression proteins | |
| AU2003241311A8 (en) | Simple catalytic dna biosensors for ions based on color changes | |
| DE69942459D1 (de) | Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung | |
| DK0973928T3 (da) | DNA-baseret transposonsystem til indføring af nukleinsyre i DNA i en celle | |
| CY1106432T1 (el) | Μεθοδος και συσκευη για ενισχυση αλληλουχιων νουκλεϊνικου οξεως με χρηση μεταφορας θepμοτητος δια ρευματων | |
| WO2005030121A3 (en) | Compounds, compositions and methods | |
| ATE356824T1 (de) | L-ribo-lna analoge | |
| DE60328383D1 (de) | Zusammensetzungen zur zuführung von nukleinsäuren an zellen | |
| ES2118593T3 (es) | Analogos de nucleotidos de pteridina como sondas fluorescentes de adn. | |
| ATE335086T1 (de) | Künstliche chromosomen, die die genetische information für die bildung von rekombinantem virus enthalten | |
| BR0315689A (pt) | Alvo para terapia de dano cognitivo | |
| WO2006031800A3 (en) | Reverse transfection of cell arrays | |
| DE69837754D1 (de) | Kombinierte tumor suppressor-gen-therapie und chemotherapie bei der neoplasmabehandlung | |
| TR199802503A3 (tr) | Endojen gen aktivasyonu için hücrelerin optimizasyonu. | |
| EP1520043A4 (de) | VERFAHREN ZUR IDENTIFIKATION DER IKKa-FUNKTION UND ANDERER GENE ZUR BEHANDLUNG VON ENTZÜNDLICHEN ERKRANKUNGEN | |
| TR199802648A3 (tr) | Gen tedavisi için nüklein asit yapilari. | |
| WO2001070777A3 (en) | Leafy cotyledon2 genes and their uses | |
| WO2003060066A8 (en) | Nucleic acid delivery and expression | |
| DE69942226D1 (de) | Unterschiedlich exprimierte gene in bauchspeicheldrüsen-krebs und -dysplasie | |
| WO2004020602A3 (en) | Terminal phosphate blocked nucleoside polyphosphates | |
| DE60016429D1 (de) | Zell- und/oder tumor-spezifische promotor-abhängige änderung der gezielten expression des herpes gamma 34.5 gens | |
| DE60130465D1 (de) | Mutierte muskelspezifische enhancer |