ATE549017T1 - Verwendung von tranilast und seinen derivaten zur behandlung von neurologischen zuständen - Google Patents
Verwendung von tranilast und seinen derivaten zur behandlung von neurologischen zuständenInfo
- Publication number
- ATE549017T1 ATE549017T1 AT08787273T AT08787273T ATE549017T1 AT E549017 T1 ATE549017 T1 AT E549017T1 AT 08787273 T AT08787273 T AT 08787273T AT 08787273 T AT08787273 T AT 08787273T AT E549017 T1 ATE549017 T1 AT E549017T1
- Authority
- AT
- Austria
- Prior art keywords
- tranilast
- derivatives
- neurological conditions
- treatment
- neuronal
- Prior art date
Links
- NZHGWWWHIYHZNX-CSKARUKUSA-N tranilast Chemical compound C1=C(OC)C(OC)=CC=C1\C=C\C(=O)NC1=CC=CC=C1C(O)=O NZHGWWWHIYHZNX-CSKARUKUSA-N 0.000 title abstract 3
- 229960005342 tranilast Drugs 0.000 title abstract 3
- 230000000926 neurological effect Effects 0.000 title abstract 2
- 230000001537 neural effect Effects 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000004069 differentiation Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 230000004112 neuroprotection Effects 0.000 abstract 1
- 230000035771 neuroregeneration Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
- 238000009168 stem cell therapy Methods 0.000 abstract 1
- 238000009580 stem-cell therapy Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07016189A EP2030617A1 (de) | 2007-08-17 | 2007-08-17 | Verwendungen von Tranilast und Derivaten daraus zur Behandlung neurologischer Leiden |
| PCT/EP2008/060745 WO2009024543A1 (en) | 2007-08-17 | 2008-08-15 | Use of tranilast and derivatives thereof for the therapy of neurological conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE549017T1 true ATE549017T1 (de) | 2012-03-15 |
Family
ID=38645596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08787273T ATE549017T1 (de) | 2007-08-17 | 2008-08-15 | Verwendung von tranilast und seinen derivaten zur behandlung von neurologischen zuständen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20110112187A1 (de) |
| EP (2) | EP2030617A1 (de) |
| AT (1) | ATE549017T1 (de) |
| AU (1) | AU2008290583A1 (de) |
| CA (1) | CA2696582A1 (de) |
| WO (1) | WO2009024543A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX352516B (es) * | 2006-07-05 | 2017-04-06 | Fibrotech Therapeutics Pty Ltd | Compuestos terapeuticos. |
| CA2709937C (en) * | 2007-12-21 | 2016-03-22 | Fibrotech Therapeutics Pty Ltd | Halogenated analogues of anti-fibrotic agents |
| CN102574843B (zh) | 2009-10-22 | 2015-06-17 | 法博太科制药有限公司 | 抗纤维化剂的稠环类似物 |
| IN2014DN09031A (de) | 2012-03-30 | 2015-05-22 | Nuformix Ltd | |
| EP4039255B1 (de) * | 2014-04-24 | 2025-10-15 | Omoidesouzou Co. Ltd. | Amyloidfaserbildungsbegrenzer oder -hemmer |
| KR101733085B1 (ko) | 2016-04-20 | 2017-05-08 | 전남대학교산학협력단 | 귀리 추출물 아베난쓰라마이드 c 또는 이의 유도체를 유효성분으로 포함하는 퇴행성 신경질환의 예방 또는 치료용 약제학적 조성물 및 건강기능식품 |
| JP7185631B2 (ja) | 2017-02-03 | 2022-12-07 | サータ セラピューティクス プロプライエタリー リミテッド | 抗線維化化合物 |
| WO2020050423A1 (ja) | 2018-09-07 | 2020-03-12 | 株式会社ファルネックス | 非ラメラ液晶形成脂質を含む外用剤 |
| CN117679520A (zh) * | 2022-09-09 | 2024-03-12 | 北京达尔文细胞生物科技有限公司 | 用于防治后遗症期面神经麻痹的药物组合物及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE222759T1 (de) * | 1996-02-07 | 2002-09-15 | Lead Chem Co Ltd | Tranilast enthaltendes externum und verfahren zu dessen herstellung |
| EP1601380A1 (de) * | 2003-02-13 | 2005-12-07 | Licentia OY | Verwendung eines mastzellen-aktivierenden oder degranulationshemmenden mittels bei der herstellung eines medikaments zur behandlung von zerebralischämie |
| US20100041756A1 (en) * | 2004-11-17 | 2010-02-18 | Michael Lionel Selley | method of modulating b cell functioning |
| JP2008526983A (ja) * | 2005-01-14 | 2008-07-24 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | T細胞の機能性を調節する方法 |
| BRPI0610349A2 (pt) * | 2005-05-16 | 2010-06-15 | Angiogen Pharmaceuticals Pty L | processos e composições para o tratamento de dor |
-
2007
- 2007-08-17 EP EP07016189A patent/EP2030617A1/de not_active Withdrawn
-
2008
- 2008-08-15 AU AU2008290583A patent/AU2008290583A1/en not_active Abandoned
- 2008-08-15 US US12/673,943 patent/US20110112187A1/en not_active Abandoned
- 2008-08-15 WO PCT/EP2008/060745 patent/WO2009024543A1/en not_active Ceased
- 2008-08-15 EP EP08787273A patent/EP2185150B1/de not_active Not-in-force
- 2008-08-15 AT AT08787273T patent/ATE549017T1/de active
- 2008-08-15 CA CA2696582A patent/CA2696582A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2185150B1 (de) | 2012-03-14 |
| WO2009024543A1 (en) | 2009-02-26 |
| EP2185150A1 (de) | 2010-05-19 |
| EP2030617A1 (de) | 2009-03-04 |
| CA2696582A1 (en) | 2009-02-26 |
| US20110112187A1 (en) | 2011-05-12 |
| AU2008290583A1 (en) | 2009-02-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE549017T1 (de) | Verwendung von tranilast und seinen derivaten zur behandlung von neurologischen zuständen | |
| ATE551063T1 (de) | Verwendung von bifidobacterium longum zur prophylaxe und behandlung von entzündungen | |
| EA201100440A1 (ru) | Соединения, композиции и способы их применения для коррекции уровня мочевой кислоты | |
| WO2009011871A3 (en) | Thiadiazole modulators of pkb | |
| MY155961A (en) | Chemical compounds 251 | |
| MY148985A (en) | 2-aminopyridine analogs as glucokinase activators | |
| WO2008046003A3 (en) | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases | |
| IL211592A0 (en) | Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries | |
| MY149143A (en) | Thiazole compounds as protien kinase b (pkb) inhibitors | |
| CR11383A (es) | Derivados piridin-2-il-amino-1,2,4 -tiadiazol como activadores glucoquinasa para el tratamiento de la diabetes mellitus | |
| WO2009011880A3 (en) | Heterocyclic modulators of pkb | |
| EA200802118A1 (ru) | Обладающие ингибирующей активностью в отношении mnk1/mnk2 тиенопиримидины, предназначенные для применения в фармацевтических композициях | |
| BRPI0810942A2 (pt) | método para tratar, previnir, retardar o início ou o desenvolvimento de uma condição, método para promover a diferenciação ou proliferação de uma célula, método para estimular o crescimento de neuritos ou para intensificar a neurogênese num indivíduo, método para auxiliar no tratamento de um indivíduo, método para diferenciar células-tronco multipotenciais, composição farmacêutica, e kit. | |
| ATE521608T1 (de) | Glucokinaseaktivatoren | |
| DE602006007093D1 (de) | Kombinationstherapie zur Behandlung von Diabetes und dadurch bedingten Leiden sowie zur Behandlung von mittels Erhöhung des GLP-1-Spiegels im Blut verbesserten Leiden | |
| BRPI0815715A8 (pt) | Compostos 5-(-4-(haloalcóxi)fenil)pirimidina-2-amina e composições como inibidores de quinases. | |
| ATE438404T1 (de) | Verwendung von k-252a und kinasehemmern zur vorbeugung und behandlung von hmgb1-assoziierten pathologien | |
| MX2009005725A (es) | Metodos y composiciones para tratamiento y monitoreo de tratamiento de trastornos asociados con il-13. | |
| WO2008156685A3 (en) | Tendon stem cells | |
| ATE501718T1 (de) | Verwendung von benzokondensierten heterocyclischen sulfamid-derivaten zur behandlung von manie und bipolaren störungen | |
| EA200800011A1 (ru) | Тиенопиримидиновые и тиенопиридиновые модуляторы киназы | |
| ATE460936T1 (de) | Pyrazoloä1,5-aüpyrimidine derivate zur verwendung in der behandlung von morbus alzheimer und verwandten leiden | |
| TW200716091A (en) | New therapeutic combinations for the treatment or prevention of psychotic disorders | |
| MX2013002208A (es) | Derivados de sulfonilpiperazina que interactuan con la proteina reguladora de glucocinasa para el tratamiento de diabetes. | |
| IL206738A0 (en) | Novel quinazoline-2,4-dione derivative, and medical compositions for the prophylaxis and treatment of cranial nerve disease containing the same |