ATE550035T1 - Allergoide aus allergenen - Google Patents

Allergoide aus allergenen

Info

Publication number: ATE550035T1
Authority: AT; Austria
Prior art keywords: allergenic material; primary amine; amine groups; functionalized; thiocarbamoyl
Prior art date: 2008-09-01

Application number

AT09748476T

Other languages

English (en)

Inventor

Giovanni Mistrello

Daniela Roncarolo

Dario Zanoni

Stefania Zanotta

Paolo Falagiani

Original Assignee

Lofarma Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-09-01

Filing date

2009-10-02

Publication date

2012-04-15

2009-10-02 Application filed by Lofarma Spa filed Critical Lofarma Spa

2012-04-15 Application granted granted Critical

2012-04-15 Publication of ATE550035T1 publication Critical patent/ATE550035T1/de

Links

239000013566 allergen Substances 0.000 title abstract 2
230000002009 allergenic effect Effects 0.000 abstract 4
239000000463 material Substances 0.000 abstract 4
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
125000000637 arginyl group Chemical group N[C@@H](CCCNC(N)=N)C(=O)* 0.000 abstract 2
230000005847 immunogenicity Effects 0.000 abstract 2
108010053156 lipid transfer protein Proteins 0.000 abstract 2
-1 thiocarbamoyl moieties Chemical group 0.000 abstract 2
241000238876 Acari Species 0.000 abstract 1
ZNZYKNKBJPZETN-WELNAUFTSA-N Dialdehyde 11678 Chemical compound N1C2=CC=CC=C2C2=C1[C@H](C[C@H](/C(=C/O)C(=O)OC)[C@@H](C=C)C=O)NCC2 ZNZYKNKBJPZETN-WELNAUFTSA-N 0.000 abstract 1
239000004472 Lysine Substances 0.000 abstract 1
KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
108010058846 Ovalbumin Proteins 0.000 abstract 1
230000005875 antibody response Effects 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
229940092253 ovalbumin Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
- A61K39/36—Allergens from pollen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Mycology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Toxicology (AREA)
Botany (AREA)
Zoology (AREA)
Analytical Chemistry (AREA)
Pulmonology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)

AT09748476T 2008-09-01 2009-10-02 Allergoide aus allergenen ATE550035T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ITMI2008A001565A IT1391559B1 (it)	2008-09-01	2008-09-01	Allergoidi derivati da allergeni
PCT/IB2009/054325 WO2010032228A1 (en)	2008-09-01	2009-10-02	Allergoids derived from allergenes

Publications (1)

Publication Number	Publication Date
ATE550035T1 true ATE550035T1 (de)	2012-04-15

Family

ID=40732204

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT09748476T ATE550035T1 (de)	2008-09-01	2009-10-02	Allergoide aus allergenen

Country Status (8)

Country	Link
US (2)	US20120114699A1 (de)
EP (1)	EP2320946B1 (de)
JP (1)	JP2013506620A (de)
AT (1)	ATE550035T1 (de)
ES (1)	ES2384680T3 (de)
IT (1)	IT1391559B1 (de)
RU (1)	RU2522490C2 (de)
WO (1)	WO2010032228A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB201011968D0 (en) *	2010-07-16	2010-09-01	Secr Defence	Toxoiding method
EP2813243B1 (de)	2013-06-11	2017-08-09	Paris-Lodron-Universität Salzburg	PRU p 3-Mimiken
WO2018187515A1 (en) *	2017-04-04	2018-10-11	Avidea Technologies, Inc.	Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response
CN112566672A (zh) *	2018-05-22	2021-03-26	阿维迪科技公司	制造基于肽的疫苗的改进方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE754523A (fr) *	1969-08-06	1971-02-08	Beecham Group Ltd	Vaccins
GB1282163A (en) *	1969-08-06	1972-07-19	Beecham Group Ltd	Modified allergens and a process for their preparation
US3893993A (en) *	1969-08-06	1975-07-08	Beecham Group Ltd	Allergenic extracts cross linked under acid conditions with inorganic cyanates
US3903067A (en) *	1969-08-06	1975-09-02	Beecham Group Ltd	Allergenic extracts reacted with epihalohydrins
US3761585A (en) *	1971-04-05	1973-09-25	Beecham Group Ltd	Vaccines containing modified allergenic material
IT1237475B (it) *	1989-10-06	1993-06-07		Allergeni modificati chimicamente e procedimento per la loro preparazione
CA2154379A1 (en) *	1994-07-22	1996-01-23	Shyam S. Mohapatra	Parietaria allergens
US5994511A (en) *	1997-07-02	1999-11-30	Genentech, Inc.	Anti-IgE antibodies and methods of improving polypeptides
AU2004224825A1 (en) *	2003-03-26	2004-10-07	Crc For Asthma Limited	Therapeutic and prophylactic compositions and uses therefor

2008
- 2008-09-01 IT ITMI2008A001565A patent/IT1391559B1/it active
2009
- 2009-10-02 ES ES09748476T patent/ES2384680T3/es active Active
- 2009-10-02 AT AT09748476T patent/ATE550035T1/de active
- 2009-10-02 JP JP2011524512A patent/JP2013506620A/ja active Pending
- 2009-10-02 EP EP09748476A patent/EP2320946B1/de active Active
- 2009-10-02 RU RU2011112405/10A patent/RU2522490C2/ru active
- 2009-10-02 WO PCT/IB2009/054325 patent/WO2010032228A1/en not_active Ceased
- 2009-10-02 US US13/059,597 patent/US20120114699A1/en not_active Abandoned
2015
- 2015-04-20 US US14/691,003 patent/US10526365B2/en active Active

Also Published As

Publication number	Publication date
US20150259378A1 (en)	2015-09-17
EP2320946B1 (de)	2012-03-21
ITMI20081565A1 (it)	2010-03-02
ES2384680T3 (es)	2012-07-10
JP2013506620A (ja)	2013-02-28
US20120114699A1 (en)	2012-05-10
WO2010032228A1 (en)	2010-03-25
IT1391559B1 (it)	2012-01-11
RU2522490C2 (ru)	2014-07-20
EP2320946A1 (de)	2011-05-18
RU2011112405A (ru)	2012-10-10
US10526365B2 (en)	2020-01-07

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