ATE551076T1 - Hämostyptikum zur topischen und inneren anwendung - Google Patents

Hämostyptikum zur topischen und inneren anwendung

Info

Publication number
ATE551076T1
ATE551076T1 AT05713806T AT05713806T ATE551076T1 AT E551076 T1 ATE551076 T1 AT E551076T1 AT 05713806 T AT05713806 T AT 05713806T AT 05713806 T AT05713806 T AT 05713806T AT E551076 T1 ATE551076 T1 AT E551076T1
Authority
AT
Austria
Prior art keywords
hemotyptic
topical
internal use
hemostatic materials
controlling
Prior art date
Application number
AT05713806T
Other languages
English (en)
Inventor
Yong Zhu
Chang Yang
Wolff Kirsch
Original Assignee
Univ Loma Linda Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Loma Linda Med filed Critical Univ Loma Linda Med
Application granted granted Critical
Publication of ATE551076T1 publication Critical patent/ATE551076T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166—Sutures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00526—Methods of manufacturing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00623—Introducing or retrieving devices therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/00884—Material properties enhancing wound closure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/00898—Material properties expandable upon contact with fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT05713806T 2004-02-23 2005-02-18 Hämostyptikum zur topischen und inneren anwendung ATE551076T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US54725704P 2004-02-23 2004-02-23
US54716604P 2004-02-23 2004-02-23
US63886504P 2004-12-22 2004-12-22
PCT/US2005/005239 WO2005081866A2 (en) 2004-02-23 2005-02-18 Hemostatic agent for topical and internal use

Publications (1)

Publication Number Publication Date
ATE551076T1 true ATE551076T1 (de) 2012-04-15

Family

ID=34916331

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05713806T ATE551076T1 (de) 2004-02-23 2005-02-18 Hämostyptikum zur topischen und inneren anwendung

Country Status (9)

Country Link
US (2) US8703176B2 (de)
EP (1) EP1718147B1 (de)
CN (2) CN1938036B (de)
AT (1) ATE551076T1 (de)
AU (1) AU2005216094B2 (de)
CA (1) CA2557042C (de)
ES (1) ES2384519T3 (de)
TW (1) TWI387467B (de)
WO (1) WO2005081866A2 (de)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7780699B2 (en) 2000-08-02 2010-08-24 Loma Linda University Medical Center Vascular wound closure device and method
US8741335B2 (en) 2002-06-14 2014-06-03 Hemcon Medical Technologies, Inc. Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as Chitosan
US20060004314A1 (en) * 2001-06-14 2006-01-05 Hemcon, Inc. Antimicrobial barriers, systems, and methods formed from hydrophilic polymer structures such as chistosan
WO2002102276A2 (en) 2001-06-14 2002-12-27 Providence Health System-Oregon Wound dressing and method for controlling severe, life-threatening bleeding
US7371403B2 (en) * 2002-06-14 2008-05-13 Providence Health System-Oregon Wound dressing and method for controlling severe, life-threatening bleeding
US8269058B2 (en) * 2002-06-14 2012-09-18 Hemcon Medical Technologies, Inc. Absorbable tissue dressing assemblies, systems, and methods formed from hydrophilic polymer sponge structures such as chitosan
US20050137512A1 (en) * 2003-12-23 2005-06-23 Campbell Todd D. Wound dressing and method for controlling severe, life-threatening bleeding
US8012167B2 (en) * 2003-08-14 2011-09-06 Loma Linda University Medical Center Vascular wound closure device and method
US8187627B2 (en) * 2003-09-05 2012-05-29 Loma Linda University Medical Center Dressing delivery system for internal wounds
US9204957B2 (en) * 2005-03-17 2015-12-08 Hemcon Medical Technologies, Inc. Systems and methods for hemorrhage control and or tissue repair
US20060229670A1 (en) * 2005-04-01 2006-10-12 Bates Brian L Method and a medical closure system for sealing a puncture
US8088145B2 (en) 2005-10-05 2012-01-03 Loma Linda University Medical Center Vascular wound closure device and method
US20070087061A1 (en) * 2005-10-14 2007-04-19 Medafor, Incorporated Method and composition for creating and/or activating a platelet-rich gel by contact with a porous particulate material, for use in wound care, tissue adhesion, or as a matrix for delivery of therapeutic components
WO2007110783A2 (en) * 2006-03-28 2007-10-04 Gustavo Larsen Method of manufacturing fibrous hemostatic bandages
DE102006020498A1 (de) 2006-04-20 2007-10-25 Aesculap Ag & Co. Kg Schichtförmige Wundauflage
JP2009538192A (ja) 2006-05-23 2009-11-05 プロビデンス ヘルス システム−オレゴン ディー／ビー／エー プロビデンス セント ビンセント メディカル センター 体の内腔または体の中空器官内に包帯構造を導入および適用するシステムおよび方法
EP3061791B1 (de) 2006-07-20 2019-01-16 OrbusNeich Medical, Inc. Bioresorbierbare polymerzusammensetzung für eine medizinische vorrichtung
EP2073754A4 (de) 2006-10-20 2012-09-26 Orbusneich Medical Inc Bioresorbierbare polymerzusammensetzung und hintergrund für eine medizinische vorrichtung
US7959942B2 (en) 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating
WO2008051445A2 (en) * 2006-10-23 2008-05-02 Valvexchange Inc. Biodegradable fastener and method of using same for rapid vascular closure
US8932560B2 (en) 2007-09-04 2015-01-13 University of Maryland, College Parke Advanced functional biocompatible polymeric matrix used as a hemostatic agent and system for damaged tissues and cells
CN102076364B (zh) 2008-05-02 2014-07-02 普罗维登斯医疗卫生系统-俄勒冈州D/B/A普罗维登斯圣文森特医疗中心 创伤敷裹装置和方法
WO2010042540A1 (en) 2008-10-06 2010-04-15 Providence Health System - Oregon Foam medical devices and methods
JP5394895B2 (ja) * 2009-11-11 2014-01-22 株式会社マキタ 電動工具
EP2498820B1 (de) 2009-11-13 2019-01-09 University of Maryland, College Park Erweiterter funktioneller biokompatibler schaumstoff als hämostasemittel für komprimierbare und nicht komprimierbare akute wunden
WO2011066471A1 (en) * 2009-11-25 2011-06-03 Loma Linda University Medical Center Chitosan-based hemostatic textile
WO2012088631A1 (zh) * 2010-12-29 2012-07-05 山东华兴纺织集团有限公司 一种壳聚糖纤维医用敷料及其制备方法
WO2012178133A1 (en) * 2011-06-24 2012-12-27 Accessclosure, Inc. Transapical closure devices and methods for use
TWI458507B (zh) * 2011-11-10 2014-11-01 Taiwan Textile Res Inst 止血纖維、止血敷材及其製造方法
SG10201610469QA (en) * 2011-11-13 2017-02-27 Cresilon Inc In-situ cross-linkable polymeric compositions and methods thereof
EP4413954A3 (de) 2011-12-06 2024-11-20 Aortic Innovations LLC Vorrichtung zur endovaskulären aortenreparatur und verfahren zur verwendung davon
US20130224712A1 (en) * 2012-02-24 2013-08-29 Bradford L. Day Medical training kits and methods to simulate treatment of uncontrolled hemorrhage
CA2914610C (en) 2013-03-13 2022-08-02 University Of Maryland Advanced functional biocompatible polymer putty used as a hemostatic agent for treating damaged tissue and cells
WO2014152796A2 (en) 2013-03-14 2014-09-25 Hemcon Medical Technologies, Inc. Biocompatible and bioabsorbable derivatized chitosan compositions
CN103191460B (zh) * 2013-04-15 2014-10-29 潘银根 壳聚糖硅酮敷料及其制备方法和用途
GB2514597A (en) * 2013-05-30 2014-12-03 Medtrade Products Ltd Degradable haemostat composition
GB2514592A (en) * 2013-05-30 2014-12-03 Medtrade Products Ltd Degradable haemostat composition
CN103480029B (zh) * 2013-07-25 2015-03-11 明基材料有限公司 止血敷料及其制造方法
US10047466B2 (en) * 2013-11-20 2018-08-14 Coreleader Biotech Co, Ltd. Bandage and method of producing the same
US9259357B2 (en) 2014-04-16 2016-02-16 Loma Linda University Composition, preparation, and use of chitosan shards for biomedical applications
AU2015301282A1 (en) * 2014-08-04 2017-03-23 James F. Drake A coherent blood coagulation structure of water-insoluble chitosan and water-dispersible starch coating
US10137219B2 (en) * 2014-08-04 2018-11-27 James F. Drake Coherent blood coagulation structure of water-insoluble chitosan and water-dispersible starch coating
US9598504B2 (en) 2014-12-16 2017-03-21 Chitogen Inc. Process for the removal of endotoxins to produce medical quality chitosan and other polysaccharides
GB201501333D0 (en) 2015-01-27 2015-03-11 Medtrade Products Ltd Composition for a wound dressing
JP2018522101A (ja) 2015-06-22 2018-08-09 クレシロン， インコーポレイテッド 高度に有用な止血用接着性ポリマー足場
JP7665280B2 (ja) 2015-12-22 2025-04-21 アクセス・バスキュラー・インコーポレイテッド 高強度生体材
DE102016103843A1 (de) 2016-03-03 2017-09-07 Biotronik Ag Reduktion von paravalvulärer Leckage durch kontrollierten Thrombusaufbau
RU2618896C1 (ru) * 2016-06-30 2017-05-11 Федеральное государственное бюджетное учреждение Гематологический научный центр Министерства здравоохранения Российской Федерации (ФГБУ ГНЦ Минздрава России) Губка гемостатическая и способ ее получения
CN106226304A (zh) * 2016-08-30 2016-12-14 广东药科大学 一种利用酸碱指示剂法测定壳寡糖脱乙酰度的方法
CN106421875B (zh) * 2016-11-15 2019-08-27 广州迈普再生医学科技股份有限公司 可降解吸收的止血纤维材料及其制备方法和止血纤维制品
US11577008B2 (en) 2017-06-21 2023-02-14 Access Vascular, Inc. High strength porous materials incorporating water soluble polymers
US11679177B2 (en) 2017-08-08 2023-06-20 Baxter International Inc. Polymeric compositions, delivery devices, and methods
EP4218844A1 (de) 2018-01-12 2023-08-02 Boston Scientific Scimed, Inc. Pulver für hämostase
RU2681184C1 (ru) * 2018-02-26 2019-03-04 Общество с ограниченной ответственностью "Специальная и медицинская техника" (ООО "Спецмедтехника") Гемостатическая губка
US10517988B1 (en) 2018-11-19 2019-12-31 Endomedix, Inc. Methods and compositions for achieving hemostasis and stable blood clot formation
US12091471B2 (en) 2018-11-19 2024-09-17 Endomedix, Inc. Methods and compositions for achieving hemostasis and stable blood clot formation
EP3897765A2 (de) 2018-12-19 2021-10-27 Access Vascular, Inc. Hochfeste poröse materialien für kontrollierte freisetzung
US12070522B2 (en) 2020-02-18 2024-08-27 Ethicon, Inc. Melt blown dressing with gradient density
WO2021178785A1 (en) 2020-03-06 2021-09-10 Access Vascular, Inc. Packaging for hydrated articles and related methods
US12102722B2 (en) 2020-06-08 2024-10-01 Ethicon, Inc. Napped coated wound dressing
US11992627B2 (en) 2020-06-30 2024-05-28 Access Vascular, Inc. Articles comprising markings and related methods
US12161777B2 (en) 2020-07-02 2024-12-10 Davol Inc. Flowable hemostatic suspension
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent
CN111956859B (zh) * 2020-09-16 2022-11-11 山东百多安医疗器械股份有限公司 一种含中药成分的抗菌止血创可贴及其制备方法
CN112300418B (zh) * 2020-09-24 2022-04-26 山东百多安医疗器械股份有限公司 一种可粘附高效止血微球及其制备方法
JP7316345B2 (ja) 2020-11-30 2023-07-27 財團法人工業技術研究院 抗カーリングフィルム
CN116744984A (zh) 2020-12-28 2023-09-12 达沃有限公司 包含蛋白质和多官能化改性的基于聚乙二醇的交联剂的反应性干粉状止血材料
CN113350673B (zh) * 2021-05-18 2022-05-27 吉林大学 一种再生障碍性贫血患者用口鼻耳腔出血紧急处理装置
CN115300664B (zh) * 2022-07-06 2023-06-20 中国石油大学(华东) 基于壳聚糖与多聚磷酸钠的喷涂式止血膜
CN115364268B (zh) * 2022-09-28 2025-10-10 杨婷婷 一种颅脑外伤用敷料及其制备方法
CN117695429B (zh) * 2023-12-15 2024-10-11 北京银河巴马生物技术股份有限公司 一种可吸收胶原止血海绵及其制备方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3390681A (en) 1966-04-04 1968-07-02 Sutures Inc Polyester suture having improved knotting characteristics
US3533940A (en) * 1967-06-02 1970-10-13 Quintin P Peniston Method for treating an aqueous medium with chitosan and derivatives of chitin to remove an impurity
US4394373A (en) * 1981-04-06 1983-07-19 Malette William Graham Method of achieving hemostasis
US4532134A (en) * 1981-04-06 1985-07-30 Malette William Graham Method of achieving hemostasis, inhibiting fibroplasia, and promoting tissue regeneration in a tissue wound
US4452785A (en) * 1982-11-08 1984-06-05 Malette William Graham Method for the therapeutic occlusion
CN1129748A (zh) * 1995-12-08 1996-08-28 中国纺织大学 脱乙酰甲壳质纤维及其制造方法和应用
US5836970A (en) * 1996-08-02 1998-11-17 The Kendall Company Hemostatic wound dressing
GB9700624D0 (en) 1997-01-14 1997-03-05 Danbiosyst Uk Drug delivery composition
US5885609A (en) * 1997-05-23 1999-03-23 Northeastern University Biocompatible articles and method for making same
US6056970A (en) * 1998-05-07 2000-05-02 Genzyme Corporation Compositions comprising hemostatic compounds and bioabsorbable polymers
DE69938612T2 (de) * 1998-11-10 2009-07-09 Netech Inc., Kawasaki Funktionelle chitosanderivate
US6060461A (en) * 1999-02-08 2000-05-09 Drake; James Franklin Topically applied clotting material
WO2001010421A1 (en) * 1999-08-06 2001-02-15 Board Of Regents, The University Of Texas System Drug releasing biodegradable fiber implant
ATE440621T1 (de) * 1999-10-07 2009-09-15 Coloplast As Chitosan enthaltender artikel zur wundbehandlung
GB9929472D0 (en) * 1999-12-13 2000-02-09 Btg Int Ltd Polymeric film
US20030206958A1 (en) * 2000-12-22 2003-11-06 Cattaneo Maurizio V. Chitosan biopolymer for the topical delivery of active agents
KR100339496B1 (ko) 2000-04-17 2002-06-05 텍산메드테크(주) 키토산 섬유 부직포 및 그 제조방법
US7780699B2 (en) * 2000-08-02 2010-08-24 Loma Linda University Medical Center Vascular wound closure device and method
US6731844B2 (en) 2001-06-21 2004-05-04 Corning Cable Systems Llc Identification of optical ribbons
KR20010079260A (ko) 2001-06-28 2001-08-22 손태원 고배향 키토산 단섬유
CA2467049C (en) * 2001-11-15 2011-04-12 Abdellatif Chenite Composition and method to homogeneously modify or cross-link chitosan under neutral conditions
US7252837B2 (en) 2002-06-28 2007-08-07 Ethicon, Inc. Hemostatic wound dressing and method of making same
US20050118238A1 (en) * 2003-06-16 2005-06-02 Zhu Yong H. Deployable hemostatic agent
AU2004253463B2 (en) * 2003-06-16 2010-12-09 Loma Linda University Medical Center Deployable multifunctional hemostatic agent

Also Published As

Publication number Publication date
CA2557042A1 (en) 2005-09-09
CN1938036B (zh) 2011-05-11
CN101897989A (zh) 2010-12-01
EP1718147B1 (de) 2012-03-28
AU2005216094A1 (en) 2005-09-09
TW200528149A (en) 2005-09-01
CA2557042C (en) 2013-06-25
WO2005081866A2 (en) 2005-09-09
US8703176B2 (en) 2014-04-22
AU2005216094B2 (en) 2010-12-23
CN1938036A (zh) 2007-03-28
EP1718147A2 (de) 2006-11-08
CN101897989B (zh) 2013-11-13
US9364578B2 (en) 2016-06-14
HK1102546A1 (en) 2007-11-30
TWI387467B (zh) 2013-03-01
EP1718147A4 (de) 2008-05-28
US20140178446A1 (en) 2014-06-26
US20050240137A1 (en) 2005-10-27
ES2384519T3 (es) 2012-07-06
WO2005081866A3 (en) 2006-11-09

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