ATE551316T1 - Verfahren zur herstellung von 6-ä3-(1-adamantyl)- 4-methoxyphenylü-2-naphtoesäure - Google Patents
Verfahren zur herstellung von 6-ä3-(1-adamantyl)- 4-methoxyphenylü-2-naphtoesäureInfo
- Publication number
- ATE551316T1 ATE551316T1 AT07870214T AT07870214T ATE551316T1 AT E551316 T1 ATE551316 T1 AT E551316T1 AT 07870214 T AT07870214 T AT 07870214T AT 07870214 T AT07870214 T AT 07870214T AT E551316 T1 ATE551316 T1 AT E551316T1
- Authority
- AT
- Austria
- Prior art keywords
- adamantyl
- methoxyphenylü
- producing
- naphtoic acid
- synthesis
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 3
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 238000003786 synthesis reaction Methods 0.000 abstract 2
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 abstract 1
- QQAMHHZQONQBFZ-UHFFFAOYSA-N 1-(5-bromo-2-methoxyphenyl)adamantane Chemical compound COC1=CC=C(Br)C=C1C1(C2)CC(C3)CC2CC3C1 QQAMHHZQONQBFZ-UHFFFAOYSA-N 0.000 abstract 1
- 238000006161 Suzuki-Miyaura coupling reaction Methods 0.000 abstract 1
- LZCDAPDGXCYOEH-UHFFFAOYSA-N adapalene Chemical compound C1=C(C(O)=O)C=CC2=CC(C3=CC=C(C(=C3)C34CC5CC(CC(C5)C3)C4)OC)=CC=C21 LZCDAPDGXCYOEH-UHFFFAOYSA-N 0.000 abstract 1
- 150000001642 boronic acid derivatives Chemical class 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- DNIAPMSPPWPWGF-UHFFFAOYSA-N monopropylene glycol Natural products CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 1
- 238000005580 one pot reaction Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 235000013772 propylene glycol Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LVP-06-149A LV13736B (en) | 2006-12-28 | 2006-12-28 | Method for manufacturing 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphtoic acid |
| PCT/EP2007/064643 WO2008086942A2 (en) | 2006-12-28 | 2007-12-28 | A method for preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphtoic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE551316T1 true ATE551316T1 (de) | 2012-04-15 |
Family
ID=39636414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07870214T ATE551316T1 (de) | 2006-12-28 | 2007-12-28 | Verfahren zur herstellung von 6-ä3-(1-adamantyl)- 4-methoxyphenylü-2-naphtoesäure |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8119835B2 (de) |
| EP (1) | EP2139839B1 (de) |
| AT (1) | ATE551316T1 (de) |
| EA (1) | EA200900897A1 (de) |
| LV (1) | LV13736B (de) |
| UA (1) | UA97509C2 (de) |
| WO (1) | WO2008086942A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2729434A1 (de) * | 2011-07-07 | 2014-05-14 | Université Catholique de Louvain | Verfahren zur durchführung von cc-kupplungsreaktionen mit oxidgeträgerten pd-katalysatoren |
| WO2015026990A2 (en) | 2013-08-20 | 2015-02-26 | University Of Washington Through Its Center For Commercialization | Novel and specific inhibitors of cytochrome p450 26 retinoic acid hydrolase |
| US11278025B2 (en) | 2017-05-17 | 2022-03-22 | The General Hospital Corporation | Antibiotic compounds |
| CN111333496B (zh) * | 2020-05-02 | 2023-10-13 | 武汉诺安药业有限公司 | 一种阿达帕林的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU744173B2 (en) * | 1997-08-28 | 2002-02-14 | Advanced Life Sciences Inc. | Robustaflavone, intermediates and analogues and method for preparation thereof |
| JP2979139B2 (ja) * | 1998-03-11 | 1999-11-15 | 東北大学長 | Ｌ−パラボロノフェニルアラニンの製造方法 |
| AR037714A1 (es) * | 2001-12-06 | 2004-12-01 | Maxia Pharmaceuticals Inc | Derivados de tiazolidinona y oxazolidinona 2-sustituidos para la inhibicion de fosfatasas y el tratamiento de cancer |
| WO2005108338A1 (en) * | 2004-05-03 | 2005-11-17 | Auspex Pharmaceuticals | Novel therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders |
| ITMI20050550A1 (it) * | 2005-04-01 | 2006-10-02 | Dipharma Spa | Procedimento per la preparazione di adapalene |
-
2006
- 2006-12-28 LV LVP-06-149A patent/LV13736B/lv unknown
-
2007
- 2007-12-28 EP EP07870214A patent/EP2139839B1/de active Active
- 2007-12-28 US US12/448,672 patent/US8119835B2/en not_active Expired - Fee Related
- 2007-12-28 AT AT07870214T patent/ATE551316T1/de active
- 2007-12-28 EA EA200900897A patent/EA200900897A1/ru unknown
- 2007-12-28 UA UAA200907981A patent/UA97509C2/ru unknown
- 2007-12-28 WO PCT/EP2007/064643 patent/WO2008086942A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008086942A2 (en) | 2008-07-24 |
| UA97509C2 (ru) | 2012-02-27 |
| US8119835B2 (en) | 2012-02-21 |
| EA200900897A1 (ru) | 2010-02-26 |
| EP2139839B1 (de) | 2012-03-28 |
| EP2139839A2 (de) | 2010-01-06 |
| LV13736B (en) | 2008-09-20 |
| WO2008086942A3 (en) | 2008-11-06 |
| US20100076219A1 (en) | 2010-03-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ606001A (en) | Derivatives of 1-amino-2-cyclobutylethylboronic acid | |
| TW200700361A (en) | Continuous process for preparing chlorohydrins | |
| DK2057126T3 (da) | Fremgangsmåde til fremstilling af 3-dihalomethyl-pyrazol-4-carboxylsyrederivater | |
| ATE551316T1 (de) | Verfahren zur herstellung von 6-ä3-(1-adamantyl)- 4-methoxyphenylü-2-naphtoesäure | |
| DE502007004351D1 (de) | Verbessertes verfahren zur herstellung von ungesättigten carbonsäureanhydriden | |
| MY148953A (en) | Substituted biphenyl carboxylic acids and derivatives thereof | |
| ATE486857T1 (de) | Verfahren zur herstellung von telmisartan | |
| ATE539150T1 (de) | Verfahren zur herstellung eines caseinhydrolysats | |
| ATE506352T1 (de) | Verfahren zur herstellung von optional 2- substituierten 1,6-dihydro-6-oxo-4- pyrimidincarboxylsäuren | |
| DE602004028054D1 (de) | Verfahren zur herstellung von bernsteinsäure aus rohhydrolysaten | |
| MY156345A (en) | Method for the production of ketoacids and their derivatives | |
| WO2008025291A8 (fr) | Système et procédé de présentation d'articles | |
| ATE512994T1 (de) | Hocheffizientes verfahren zur herstellung von polyalkylenoxidcarbonsäuren | |
| ATE537159T1 (de) | Verfahren zur herstellung von glycidylestern | |
| ATE489355T1 (de) | Mandelsäurederivate und deren herstellung | |
| DE50109832D1 (de) | Verfahren zur herstellung von essigsäure | |
| ATE396964T1 (de) | Verfahren zur herstellung von phthalsauredichlorid | |
| IL173524A0 (en) | Production process of optically pure 2-(4-hydroxyphenoxy)- propanoic acid compounds | |
| DE602006002738D1 (de) | Verbessertes Verfahren zur Herstellung von Moxonidine | |
| DK1765770T3 (da) | Fremgangsmåde til fremstilling af gabapentin | |
| DE602006012622D1 (de) | Verfahren zur herstellung von 1,1,1-tris(4-hydroxyphenyl)alkanen | |
| PL1868980T3 (pl) | Nowy sposób wytwarzania kwasu 6-[3-(1-adamantylo)-4-metoksyfenylo]-2-naftoesowego | |
| DE602006005515D1 (de) | Verfahren zur herstellung von citronellal | |
| ATE416156T1 (de) | Verfahren zur herstellung von acetessigsäurearylamiden | |
| DE602008005414D1 (de) | Verfahren zur gewinnung von propionsäure |