ATE552251T1 - Thiophen- und furanverbindungen - Google Patents
Thiophen- und furanverbindungenInfo
- Publication number
- ATE552251T1 ATE552251T1 AT05704861T AT05704861T ATE552251T1 AT E552251 T1 ATE552251 T1 AT E552251T1 AT 05704861 T AT05704861 T AT 05704861T AT 05704861 T AT05704861 T AT 05704861T AT E552251 T1 ATE552251 T1 AT E552251T1
- Authority
- AT
- Austria
- Prior art keywords
- thiophene
- furan compounds
- alzheimer
- schizophrenia
- relates
- Prior art date
Links
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title abstract 4
- 229930192474 thiophene Natural products 0.000 title abstract 2
- YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical class C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 title 1
- 201000000980 schizophrenia Diseases 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 206010012289 Dementia Diseases 0.000 abstract 1
- 230000007278 cognition impairment Effects 0.000 abstract 1
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 150000002240 furans Chemical class 0.000 abstract 1
- 208000027061 mild cognitive impairment Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04380005 | 2004-01-09 | ||
| US55208004P | 2004-03-10 | 2004-03-10 | |
| PCT/US2005/000004 WO2005070916A1 (en) | 2004-01-09 | 2005-01-05 | Thiophene and furan compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE552251T1 true ATE552251T1 (de) | 2012-04-15 |
Family
ID=45935348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05704861T ATE552251T1 (de) | 2004-01-09 | 2005-01-05 | Thiophen- und furanverbindungen |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7642361B2 (de) |
| EP (1) | EP1706395B1 (de) |
| AT (1) | ATE552251T1 (de) |
| ES (1) | ES2383115T3 (de) |
| WO (1) | WO2005070916A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602006003661D1 (de) | 2005-06-06 | 2008-12-24 | Lilly Co Eli | Ampa-rezeptoren-verstärker |
| TW200817385A (en) * | 2006-07-04 | 2008-04-16 | Organon Nv | Heterocyclic derivatives |
| JP2010143826A (ja) * | 2007-04-12 | 2010-07-01 | Mitsui Chemicals Inc | ３−アミノチオフェン誘導体の製造方法 |
| TW200934497A (en) * | 2007-11-13 | 2009-08-16 | Organon Nv | Heterocyclic derivatives |
| US8877816B2 (en) * | 2007-11-21 | 2014-11-04 | Decode Genetics Ehf | 4-(or 5-) substituted catechol derivatives |
| TW201012803A (en) | 2008-06-06 | 2010-04-01 | Organon Nv | Heterocyclic derivatives |
| US20100016609A1 (en) * | 2008-07-15 | 2010-01-21 | Wyeth | Methods for the preparation of azole compounds |
| US8680139B2 (en) | 2009-04-01 | 2014-03-25 | Progenra | Anti-neoplastic compounds, compositions and methods |
| US8633237B2 (en) | 2009-04-09 | 2014-01-21 | Merck Sharp & Dohme B.V. | Indane derivatives |
| JP2014500303A (ja) * | 2010-12-22 | 2014-01-09 | パーデュー、ファーマ、リミテッド、パートナーシップ | ナトリウムチャネル遮断剤としての置換ピリジン |
| ES2865412T3 (es) * | 2012-09-21 | 2021-10-15 | Rhode Island Hospital | Inhibidores de beta-hidrolasa para tratamiento del cáncer |
| WO2014078568A1 (en) | 2012-11-14 | 2014-05-22 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| EP3263559A1 (de) * | 2013-01-22 | 2018-01-03 | Technische Universität Graz | Lipaseinhibitoren |
| RU2015143517A (ru) | 2013-03-13 | 2017-04-19 | Дженентек, Инк. | Пиразолсодержащие соединения и их применения |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0273602A1 (de) * | 1986-12-05 | 1988-07-06 | Eli Lilly And Company | 3-Cyano-4-arylthiophene |
| PE20000942A1 (es) * | 1998-07-31 | 2000-09-28 | Lilly Co Eli | Derivados de amida, carbamato y urea |
| WO2001032604A1 (en) * | 1999-11-05 | 2001-05-10 | University College London | Activators of soluble guanylate cyclase |
| US6835745B2 (en) * | 2002-01-15 | 2004-12-28 | Wyeth | Phenyl substituted thiophenes as estrogenic agents |
| US20030181468A1 (en) * | 2002-03-21 | 2003-09-25 | Michaelides Michael R. | Thiopyrimidine and isothiazolopyrimidine kinase inhibitors |
-
2005
- 2005-01-05 AT AT05704861T patent/ATE552251T1/de active
- 2005-01-05 US US10/596,419 patent/US7642361B2/en not_active Expired - Fee Related
- 2005-01-05 EP EP05704861A patent/EP1706395B1/de not_active Expired - Lifetime
- 2005-01-05 WO PCT/US2005/000004 patent/WO2005070916A1/en not_active Ceased
- 2005-01-05 ES ES05704861T patent/ES2383115T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2383115T3 (es) | 2012-06-18 |
| WO2005070916A1 (en) | 2005-08-04 |
| EP1706395A1 (de) | 2006-10-04 |
| US7642361B2 (en) | 2010-01-05 |
| US20070105852A1 (en) | 2007-05-10 |
| EP1706395B1 (de) | 2012-04-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ595571A (en) | Pyrazole compounds and uses thereof | |
| GB0421639D0 (en) | Methods and compositions relating to alzheimer's disease | |
| NO20054640D0 (no) | Fremgangsmater for behandling av Parkinsons sykdom | |
| BRPI0413022A (pt) | derivados de 3-amino cromado e 2-amino tetralina | |
| ATE535236T1 (de) | Therapeutische strategien für die prävention und behandlung der alzheimer-krankheit | |
| DK1594833T3 (da) | 1-phenylalkancarboxylsyrederivater til behandling af neurodegenerative sygdomme | |
| BR0314059A (pt) | Compostos heterocìclicos | |
| ATE355278T1 (de) | Isochinolinon derivate als parp inhibitoren | |
| PL1765388T3 (pl) | Terapia skojarzona do zapobiegania chorobie Alzheimera lub leczenia tej choroby oraz zestaw do tego celu | |
| TW200736255A (en) | 5-(Substituted)-pyrazolopiperidines | |
| BRPI0515528A (pt) | n-metil hidroxietilamina úteis no tratamento de condições do sistema nervoso central | |
| ATE534391T1 (de) | 3,11b-cis-dihydrotetrabenazin zur behandlung von psychosen | |
| WO2009009393A3 (en) | Chromium complexes for improvement of memory and cognitive function | |
| ATE486597T1 (de) | 3,4-substituierte pyrrolidin-derivate zur behandlung von hypertonie | |
| IL177787A0 (en) | 1-aminovyclohexane derivatives for the treatment of agitation and other behavioral disorders, especially those associated with alzheimer's disease | |
| IL163026A (en) | Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders | |
| DE60304695D1 (de) | 7-ARYLSULFONAMID-2,3,4,5-TETRAHYDRO-1H-BENZOiDöAZEPINE MIT 5-HT6 REZEPTOR AFFINITÄT ZUR BEHANDLUNG VON ZENTRALNERVENSYSTEMERKRANKUNGEN | |
| EA200800880A1 (ru) | Комбинация росиглитазона и донепезила, предназначенная для улучшения когнитивной функции | |
| BRPI0510947A (pt) | tratamento de doença respiratória | |
| DK1463735T3 (da) | Imidazo-2,1-B -1,3,4-thiadiazol-sulfonamider | |
| CR11447A (es) | Moduladores de piperidinil y piperazinil de y secretasa | |
| EP1817311A4 (de) | 2,3,4,6-substituierte pyridylderivat-verbindungen als beta-sektretase-inhibitoren zur behandlung von morbus alzheimer | |
| TW200716152A (en) | Substituted 1,2-ethylendiamines, medicaments comprising said compound, their use and their method of manufacture | |
| EA200801302A1 (ru) | Композиции и способы лечения нарушений цнс | |
| DE602004019541D1 (de) | Cycloalkyläbü kondensierte indole |