ATE553693T1 - Erweitertes fokalregion-messgerät und -verfahren - Google Patents

Erweitertes fokalregion-messgerät und -verfahren

Info

Publication number
ATE553693T1
ATE553693T1 AT04798653T AT04798653T ATE553693T1 AT E553693 T1 ATE553693 T1 AT E553693T1 AT 04798653 T AT04798653 T AT 04798653T AT 04798653 T AT04798653 T AT 04798653T AT E553693 T1 ATE553693 T1 AT E553693T1
Authority
AT
Austria
Prior art keywords
section
focal region
derived
refractive index
light
Prior art date
Application number
AT04798653T
Other languages
English (en)
Inventor
Daniel Daly
Graeme Clark
Original Assignee
Lein Applied Diagnostics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lein Applied Diagnostics Ltd filed Critical Lein Applied Diagnostics Ltd
Application granted granted Critical
Publication of ATE553693T1 publication Critical patent/ATE553693T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/1005—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring distances inside the eye, e.g. thickness of the cornea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6814—Head
    • A61B5/6821—Eye
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B11/00—Measuring arrangements characterised by the use of optical techniques
    • G01B11/02—Measuring arrangements characterised by the use of optical techniques for measuring length, width or thickness

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Emergency Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Eye Examination Apparatus (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
AT04798653T 2003-12-12 2004-11-24 Erweitertes fokalregion-messgerät und -verfahren ATE553693T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0328866A GB2409033C (en) 2003-12-12 2003-12-12 Extended focal region measuring apparatus and method
PCT/GB2004/004946 WO2005058152A1 (en) 2003-12-12 2004-11-24 Extended focal region measuring apparatus and method

Publications (1)

Publication Number Publication Date
ATE553693T1 true ATE553693T1 (de) 2012-05-15

Family

ID=30130136

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04798653T ATE553693T1 (de) 2003-12-12 2004-11-24 Erweitertes fokalregion-messgerät und -verfahren

Country Status (5)

Country Link
US (1) US8078245B2 (de)
EP (1) EP1694199B1 (de)
AT (1) ATE553693T1 (de)
GB (1) GB2409033C (de)
WO (1) WO2005058152A1 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005059923A1 (de) * 2005-12-13 2007-06-14 Oculus Optikgeräte GmbH Verfahren und Vorrichtung zur Bestimmung des Abstandes zu einem Messpunkt auf einer Gewebefläche des Auges
US20090128824A1 (en) * 2006-01-24 2009-05-21 Rainer Leitgeb Optical imaging system with extended depth of focus
US20070191682A1 (en) * 2006-02-15 2007-08-16 Jannick Rolland Optical probes for imaging narrow vessels or lumens
CA2647147C (en) 2006-04-11 2016-10-04 Neuroptix Corporation Ocular imaging
ES2314793T3 (es) 2006-07-24 2009-03-16 Eyesense Ag Dispositivo para medir un analito en un fluido ocular.
US7621638B2 (en) * 2006-11-29 2009-11-24 Clarity Medical Systems, Inc. Delivering a short Arc lamp light for eye imaging
GB2451441B (en) 2007-07-30 2012-07-11 Lein Applied Diagnostics Ltd Optical alignment apparatus and method thereof
GB2451442B (en) * 2007-07-30 2013-03-06 Lein Applied Diagnostics Ltd Optical measurement apparatus and method therefor
GB2451443B (en) * 2007-07-30 2012-12-26 Lein Applied Diagnostics Ltd Optical measurement apparatus and method therefor
GB2457302B (en) 2008-02-11 2013-04-10 Lein Applied Diagnostics Ltd Measurement apparatus and method therefor
US8364218B2 (en) 2008-02-11 2013-01-29 Glucovista, Inc. Apparatus and method for non-invasive measurement of the concentration of a substance in subjects blood
US8219169B2 (en) * 2008-02-11 2012-07-10 Glucovista Inc. Apparatus and method using light retro-reflected from a retina to non-invasively measure the blood concentration of a substance
US10646116B2 (en) * 2013-07-25 2020-05-12 Amo Development, Llc In situ determination of refractive index of materials
SG188900A1 (en) 2008-03-27 2013-04-30 Neuroptix Corp Ocular imaging
GB2467340B (en) 2009-01-30 2013-11-13 Lein Applied Diagnostics Ltd Signal sample trigger apparatus, data acquisition system and method of sampling an analogue signal
DE102010010569A1 (de) * 2010-03-05 2011-09-08 Andreas Schnalke Diagnosevorrichtung zur Detektion einer Schichtgrenze in einem Auge sowie Ringelement für die Diagnosevorrichtung
CA2807683C (en) 2010-08-16 2020-02-18 Cognoptix, Inc. System and method for detecting amyloid proteins
DE102010048294B4 (de) * 2010-10-14 2021-02-18 Deutsch-Französisches Forschungsinstitut Saint-Louis Laseranordnung mit einer Phasenfrontregelung
KR101350976B1 (ko) * 2010-12-22 2014-01-14 한국기초과학지원연구원 온도분포 측정장치
US8928874B2 (en) 2012-02-24 2015-01-06 Mitutoyo Corporation Method for identifying abnormal spectral profiles measured by a chromatic confocal range sensor
US8860931B2 (en) * 2012-02-24 2014-10-14 Mitutoyo Corporation Chromatic range sensor including measurement reliability characterization
US20150157199A1 (en) * 2012-12-06 2015-06-11 Noam Sapiens Method and apparatus for scatterometric measurement of human tissue
CN103300816A (zh) * 2013-05-30 2013-09-18 中国科学院长春光学精密机械与物理研究所 一种眼底相机的环形照明装置
US9464883B2 (en) 2013-06-23 2016-10-11 Eric Swanson Integrated optical coherence tomography systems and methods
US9683928B2 (en) 2013-06-23 2017-06-20 Eric Swanson Integrated optical system and components utilizing tunable optical sources and coherent detection and phased array for imaging, ranging, sensing, communications and other applications
US10441463B2 (en) 2014-03-26 2019-10-15 Optimedica Corporation Confocal laser eye surgery system and improved confocal bypass assembly
US10441465B2 (en) 2014-03-26 2019-10-15 Optimedica Corporation Registration of LOI fiducials with camera
WO2015147925A1 (en) 2014-03-26 2015-10-01 Optimedica Corporation Confocal laser eye surgery system
WO2015154105A1 (en) * 2014-04-11 2015-10-15 Margaryan Hakob Device for non-invasive determination of glucose concentration in human organism
CA2991731A1 (en) * 2014-07-17 2016-01-21 I Sonic Medical Corporation, S.A.S. Measurement of ocular parameters using vibrations induced in the eye
WO2016054079A1 (en) 2014-09-29 2016-04-07 Zyomed Corp. Systems and methods for blood glucose and other analyte detection and measurement using collision computing
GB2533958A (en) * 2015-01-09 2016-07-13 Nokia Technologies Oy Method, apparatus and computer program for determining focusing information
US20160357007A1 (en) 2015-05-05 2016-12-08 Eric Swanson Fixed distal optics endoscope employing multicore fiber
US20170255012A1 (en) * 2016-03-04 2017-09-07 Sharp Kabushiki Kaisha Head mounted display using spatial light modulator to move the viewing zone
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
US10969571B2 (en) 2016-05-30 2021-04-06 Eric Swanson Few-mode fiber endoscope
WO2018000036A1 (en) * 2016-07-01 2018-01-04 Cylite Pty Ltd Apparatus and method for confocal microscopy using dispersed structured illumination
IT201600117339A1 (it) * 2016-11-21 2018-05-21 Crestoptics S P A Apparato a super-risoluzione spaziale per l’analisi in fluorescenza del fondo dell’occhio
DE102017108193A1 (de) * 2017-04-18 2018-10-18 Rowiak Gmbh OCT-Bilderfassungvorrichtung
SI3492905T1 (sl) 2017-11-30 2020-07-31 Volumen d.o.o. Fototermični interferometer
WO2019108227A1 (en) * 2017-12-01 2019-06-06 Xinova, LLC Polarization filtering for improved eye imaging
BE1026154B1 (fr) * 2018-03-27 2019-10-29 Laser Engineering Applications Système optique
CN113366343A (zh) * 2019-01-07 2021-09-07 兰斯芙丽有限公司 用于在成像中使用的系统和方法
US11681093B2 (en) 2020-05-04 2023-06-20 Eric Swanson Multicore fiber with distal motor
US11802759B2 (en) 2020-05-13 2023-10-31 Eric Swanson Integrated photonic chip with coherent receiver and variable optical delay for imaging, sensing, and ranging applications
US20220117524A1 (en) * 2021-12-25 2022-04-21 Pai-Chang Yeh Apparatus, method and device for non-contact and non-invasive blood sugar monitoring to help monitor diabetic patients and hypercoagulation
CN114468976B (zh) * 2021-12-31 2026-03-10 成都益英光电科技有限公司 一种基于睫状体的人眼实物焦距通用探测方法、装置
US12085387B1 (en) 2023-09-23 2024-09-10 Hamamatsu Photonics K.K. Optical coherence tomography system for subsurface inspection
KR102875104B1 (ko) * 2023-11-14 2025-10-21 주식회사 휴비츠 개선된 신호 대 잡음비를 가지는 자동 굴절검사기

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3963019A (en) 1974-11-25 1976-06-15 Quandt Robert S Ocular testing method and apparatus
US3958560A (en) 1974-11-25 1976-05-25 Wayne Front March Non-invasive automatic glucose sensor system
US4014321A (en) 1974-11-25 1977-03-29 March Wayne F Non-invasive glucose sensor system
US4154114A (en) * 1977-12-02 1979-05-15 Sonometrics Systems, Inc. Biometric measuring device
DE3037983C2 (de) 1980-10-08 1983-03-31 Fa. Carl Zeiss, 7920 Heidenheim Verfahren und Vorrichtung zur lichtinduzierten rastermikroskopischen Darstellung von Probenparametern in ihrer räumlichen Verteilung
IT1198660B (it) 1983-08-02 1988-12-21 Ottica Ist Naz Profilometro ottico multifocale per dispersione
US4750830A (en) 1985-11-29 1988-06-14 Lee Arnold St J Method and apparatus for monitoring blood-glucose concentration by measuring focal properties of the eye
US4806004A (en) 1987-07-10 1989-02-21 California Institute Of Technology Scanning microscopy
US6066847A (en) 1989-01-19 2000-05-23 Futrex Inc. Procedure for verifying the accuracy of non-invasive blood glucose measurement instruments
US5152759A (en) * 1989-06-07 1992-10-06 University Of Miami, School Of Medicine, Dept. Of Ophthalmology Noncontact laser microsurgical apparatus
WO1992001417A1 (en) * 1990-07-19 1992-02-06 Horwitz Larry S Vision measurement and correction
US5209231A (en) 1990-11-02 1993-05-11 University Of Connecticut Optical glucose sensor apparatus and method
US5203328A (en) * 1991-07-17 1993-04-20 Georgia Tech Research Corporation Apparatus and methods for quantitatively measuring molecular changes in the ocular lens
JPH07508426A (ja) 1991-10-17 1995-09-21 サイエンティフィック　ジェネリクス　リミテッド 血液検体測定装置及びその方法
US5433197A (en) 1992-09-04 1995-07-18 Stark; Edward W. Non-invasive glucose measurement method and apparatus
US5553617A (en) 1995-01-20 1996-09-10 Hughes Aircraft Company Noninvasive method and apparatus for determining body chemistry
US5785651A (en) 1995-06-07 1998-07-28 Keravision, Inc. Distance measuring confocal microscope
DE19538372A1 (de) 1995-10-14 1997-04-17 Laser & Med Tech Gmbh Nicht invasive Glukosemessung
IL117241A (en) * 1996-02-23 2000-09-28 Talia Technology Ltd Three dimensional imaging apparatus and a method for use thereof
JP3599878B2 (ja) 1996-03-01 2004-12-08 テルモ株式会社 血糖計
JP3604231B2 (ja) 1996-05-16 2004-12-22 富士写真フイルム株式会社 グルコース濃度測定方法および装置
US5880465A (en) 1996-05-31 1999-03-09 Kovex Corporation Scanning confocal microscope with oscillating objective lens
US5854078A (en) 1996-11-06 1998-12-29 University Of Pittsburgh Polymerized crystalline colloidal array sensor methods
JP3543923B2 (ja) * 1997-12-25 2004-07-21 富士写真フイルム株式会社 グルコース濃度測定装置
AU2989699A (en) 1998-03-05 1999-09-20 Universal Health-Watch, Inc. Apparatus to non-invasively measure glucose or other constituents in aqueous humor using infra-red spectroscopy
US6188477B1 (en) 1998-05-04 2001-02-13 Cornell Research Foundation, Inc. Optical polarization sensing apparatus and method
US6574501B2 (en) 1998-07-13 2003-06-03 Childrens Hospital Los Angeles Assessing blood brain barrier dynamics or identifying or measuring selected substances or toxins in a subject by analyzing Raman spectrum signals of selected regions in the eye
CA2337097C (en) 1998-07-13 2008-12-23 James L. Lambert Non-invasive glucose monitor
JP3848492B2 (ja) 1998-09-04 2006-11-22 株式会社ニデック 角膜手術装置
US6853854B1 (en) 1998-09-18 2005-02-08 Q Step Technologies, Llc Noninvasive measurement system
US6438396B1 (en) * 1998-11-05 2002-08-20 Cytometrics, Inc. Method and apparatus for providing high contrast imaging
AU4063100A (en) 1999-04-01 2000-10-23 University Of Connecticut, The Optical glucose sensor apparatus and method
US6442410B1 (en) 1999-06-10 2002-08-27 Georgia Tech Research Corp. Non-invasive blood glucose measurement system and method using optical refractometry
US6382794B1 (en) * 1999-09-27 2002-05-07 Carl Zeiss, Inc. Method and apparatus for mapping a corneal contour and thickness profile
US6961599B2 (en) 2001-01-09 2005-11-01 Childrens Hospital Los Angeles Identifying or measuring selected substances or toxins in a subject using resonant raman signals
WO2002080760A1 (de) * 2001-04-09 2002-10-17 Sis Ag Surgical Instrument Systems Verfahren und vorrichtungsanordnung zur bestimmung der hornhautdicke eines auges
JP4152193B2 (ja) 2001-04-27 2008-09-17 アイセンス・アクチエンゲゼルシャフト 血中グルコース濃度計測装置
US6704588B2 (en) 2001-06-16 2004-03-09 Rafat R. Ansari Method and apparatus for the non-invasive measurement of blood glucose levels in humans
CN1319486C (zh) 2001-08-02 2007-06-06 乔纳森·格利茨 非侵入式葡萄糖计
US6836337B2 (en) 2001-09-20 2004-12-28 Visual Pathways, Inc. Non-invasive blood glucose monitoring by interferometry
US6934035B2 (en) 2001-12-18 2005-08-23 Massachusetts Institute Of Technology System and method for measuring optical distance
AU2003233468A1 (en) 2002-04-05 2003-10-27 Eyelab Group, Llc Monitoring blood substances using self-sampled tears
US6885882B2 (en) 2002-05-28 2005-04-26 Cote Gerard L. Method and apparatus for non-invasive glucose sensing through the eye
US6895264B2 (en) 2002-08-26 2005-05-17 Fovioptics Inc. Non-invasive psychophysical measurement of glucose using photodynamics
US6988995B2 (en) * 2002-09-30 2006-01-24 Carl Zeiss Meditec, Inc. Method and system for detecting the effects of Alzheimer's disease in the human retina
WO2004034894A1 (en) * 2002-10-16 2004-04-29 Campbell Science Group, Inc. Cornea characteristics measuring device
CA2454894A1 (en) 2003-01-07 2004-07-07 Intelligent Photonics Control Corp. Non-invasive blood monitor
DE10302849A1 (de) 2003-01-23 2004-07-29 Carl Zeiss Meditec Ag Verfahren und Anordnung zur Messung der Dispersion in transparenten Medien
US20080249381A1 (en) 2004-06-14 2008-10-09 Eyesense Ag Combined Apparatus For Measuring the Blood Glucose Level From an Ocular Fluid

Also Published As

Publication number Publication date
US8078245B2 (en) 2011-12-13
GB2409033B (en) 2006-05-24
US20070123761A1 (en) 2007-05-31
WO2005058152A1 (en) 2005-06-30
GB2409033A (en) 2005-06-15
EP1694199B1 (de) 2012-04-18
GB0328866D0 (en) 2004-01-14
EP1694199A1 (de) 2006-08-30
GB2409033C (en) 2006-05-24

Similar Documents

Publication Publication Date Title
ATE553693T1 (de) Erweitertes fokalregion-messgerät und -verfahren
Tura et al. Non-invasive glucose monitoring: Assessment of technologies and devices according to quantitative criteria
DE602004030474D1 (de) Erfahren dafür
US9560971B2 (en) Physiological information measuring apparatus
Chang et al. Biphasic direct current shift, haemoglobin desaturation and neurovascular uncoupling in cortical spreading depression
US10499839B1 (en) Optimized biophotonic sensors
CN118986289A (zh) 用于组织测量的传感器
BR112015019505A2 (pt) análises de sangue não-invasivas
ATE539674T1 (de) Nichtinvasive blutanalyse durch optische sondierung der venen unter der zunge
CA2352201A1 (en) Non-invasive sensor capable of determining optical parameters in a sample having multiple layers
CN101264019A (zh) 一种基于光声技术的新型便携式无创、连续、实时血糖监测仪
CN111956234A (zh) 基于光声技术的血氧饱和度精确测量方法及设备
CN204636382U (zh) 可调焦距的动态光声无创伤血糖仪
JP2019201760A (ja) 血管検知装置及びその方法
JP2005319290A (ja) 微小循環を観測する非侵襲的方法
WO2006097933A3 (en) Method for monitoring changes in blood glucose level
Song et al. Speckle variance photoacoustic microscopy for microhemodynamic imaging
KR20200099545A (ko) 지질계측장치 및 그 방법
WO2025102900A1 (zh) 无创血糖检测系统
Ergin et al. Noninvasive detection of glucose in porcine eyes
EP2241245A1 (de) Verwendung von Erfassung der Muskelspannung zur Kontrolle der Position eines Körperteils
Pavithra et al. Non invasive technique to measure glucose and haemoglobin level in blood using NIR-occlusion spectroscopy
CN208447606U (zh) 多级散射聚焦调控血液参数监测装置
Li et al. A Novel Quantitative Hemodynamic Evaluation Method of Laser Therapy for Scars Based on Diffuse Correlation Spectroscopy
RU2373846C1 (ru) Устройство для неинвазивного определения параметров крови