ATE55390T1 - Senfgas-derivate der c-6-aminogalaktose und ihre verwendung. - Google Patents

Senfgas-derivate der c-6-aminogalaktose und ihre verwendung.

Info

Publication number: ATE55390T1
Authority: AT; Austria
Prior art keywords: sub; group; aminogalcose; proviso; sulfonate
Prior art date: 1984-10-31

Application number

AT85307874T

Other languages

English (en)

Inventor

Eugene Mcpherson

Philip S Schein

Original Assignee

Univ Georgetown

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-31

Filing date

1985-10-30

Publication date

1990-08-15

1985-10-30 Application filed by Univ Georgetown filed Critical Univ Georgetown

1990-08-15 Application granted granted Critical

1990-08-15 Publication of ATE55390T1 publication Critical patent/ATE55390T1/de

Links

QKSKPIVNLNLAAV-UHFFFAOYSA-N bis(2-chloroethyl) sulfide Chemical class ClCCSCCCl QKSKPIVNLNLAAV-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 2
WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical group OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 2
150000001720 carbohydrates Chemical group 0.000 abstract 2
BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000032823 cell division Effects 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000000654 isopropylidene group Chemical group C(C)(C)=* 0.000 abstract 1
125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000002194 synthesizing effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Crystallography & Structural Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Seasonings (AREA)
Cosmetics (AREA)

AT85307874T 1984-10-31 1985-10-30 Senfgas-derivate der c-6-aminogalaktose und ihre verwendung. ATE55390T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/666,904 US4656159A (en)	1984-10-31	1984-10-31	Galactose-C-6 nitrogen mustard compounds and their uses
EP85307874A EP0181154B1 (de)	1984-10-31	1985-10-30	Senfgas-Derivate der C-6-Aminogalaktose und ihre Verwendung

Publications (1)

Publication Number	Publication Date
ATE55390T1 true ATE55390T1 (de)	1990-08-15

Family

ID=24675999

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT85307874T ATE55390T1 (de)	1984-10-31	1985-10-30	Senfgas-derivate der c-6-aminogalaktose und ihre verwendung.

Country Status (5)

Country	Link
US (1)	US4656159A (de)
EP (1)	EP0181154B1 (de)
JP (1)	JPS61118394A (de)
AT (1)	ATE55390T1 (de)
DE (1)	DE3579110D1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE94395T1 (de) *	1986-05-09	1993-10-15	Pulverer Gerhard	Verwendung von spezifischen monosacchariden zur herstellung eines arzneimittels zur verhinderung von metastasen maligner tumore.
US5126438A (en) *	1990-12-07	1992-06-30	Hawaiian Sugar Planters' Association	6,6'-dihalo-6,6'-dideoxy-1',2,3,3',4,4'-hexa-o-methylsucrose compounds
US6075134A (en) *	1997-05-15	2000-06-13	The Regents Of The University Of California	Glycoconjugates and methods
CN1264616C (zh) *	2001-09-07	2006-07-19	株式会社神户制钢所	废弃化学武器中固体残渣的中和处理方法
US20050220862A1 (en) *	2004-03-31	2005-10-06	Bernstein Joel E	Compositions with reduced hepatotoxicity
JP5702600B2 (ja) *	2007-07-03	2015-04-15	チルドレンズホスピタルアンドリサーチセンターアットオークランド	オリゴシアル酸誘導体、製造方法および免疫学的使用
US8999954B2 (en) *	2007-07-03	2015-04-07	Childern's Hospital & Research Center at Oakland	Inhibitors of polysialic acid de-N-acetylase and methods for using the same
JP5523313B2 (ja)	2007-07-03	2014-06-18	チルドレンズホスピタルアンドリサーチセンターアットオークランド	ポリシアル酸誘導体、製造方法、ならびにがん抗原産生の増強およびターゲティングにおける使用
US8193182B2 (en)	2008-01-04	2012-06-05	Intellikine, Inc.	Substituted isoquinolin-1(2H)-ones, and methods of use thereof
AU2009204483B2 (en)	2008-01-04	2014-03-13	Intellikine, Llc	Certain chemical entities, compositions and methods
WO2010036380A1 (en)	2008-09-26	2010-04-01	Intellikine, Inc.	Heterocyclic kinase inhibitors
WO2010129816A2 (en)	2009-05-07	2010-11-11	Intellikine, Inc.	Heterocyclic compounds and uses thereof
JP5951600B2 (ja)	2010-05-21	2016-07-13	インフィニティーファーマシューティカルズ，インコーポレイテッド	キナーゼ調節のための、化合物、組成物および方法
US8901133B2 (en)	2010-11-10	2014-12-02	Infinity Pharmaceuticals, Inc.	Heterocyclic compounds and uses thereof
KR20180080358A (ko)	2011-01-10	2018-07-11	인피니티 파마슈티칼스, 인코포레이티드	이소퀴놀린온 및 이의 고체 형태의 제조 방법
EP2734530A1 (de)	2011-07-19	2014-05-28	Infinity Pharmaceuticals, Inc.	Heterocyclische verbindungen und ihre verwendung
CN103930422A (zh)	2011-07-19	2014-07-16	无限药品股份有限公司	杂环化合物及其用途
CN103998442B (zh)	2011-08-29	2016-09-14	无限药品股份有限公司	杂环化合物及其用途
US8940742B2 (en)	2012-04-10	2015-01-27	Infinity Pharmaceuticals, Inc.	Heterocyclic compounds and uses thereof
US8828998B2 (en)	2012-06-25	2014-09-09	Infinity Pharmaceuticals, Inc.	Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
IL291945B2 (en)	2012-11-01	2025-11-01	Infinity Pharmaceuticals Inc	Treatment of cancers using pi3 kinase isoform modulators
US9481667B2 (en)	2013-03-15	2016-11-01	Infinity Pharmaceuticals, Inc.	Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
MX389256B (es)	2013-10-04	2025-03-20	Infinity Pharmaceuticals Inc	Compuestos heterociclicos y usos de los mismos.
WO2015051241A1 (en)	2013-10-04	2015-04-09	Infinity Pharmaceuticals, Inc.	Heterocyclic compounds and uses thereof
EP4066834A1 (de)	2014-03-19	2022-10-05	Infinity Pharmaceuticals, Inc.	Heterocyclische verbindungen zur verwendung in der behandlung von pi3k-gamma-vermittelten erkrankungen
US20150320755A1 (en)	2014-04-16	2015-11-12	Infinity Pharmaceuticals, Inc.	Combination therapies
WO2016054491A1 (en)	2014-10-03	2016-04-07	Infinity Pharmaceuticals, Inc.	Heterocyclic compounds and uses thereof
CN108349985A (zh)	2015-09-14	2018-07-31	无限药品股份有限公司	异喹啉酮的固体形式、其制备方法、包含其的组合物及其使用方法
US10759806B2 (en)	2016-03-17	2020-09-01	Infinity Pharmaceuticals, Inc.	Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as PI3K kinase inhibitors
WO2017214269A1 (en)	2016-06-08	2017-12-14	Infinity Pharmaceuticals, Inc.	Heterocyclic compounds and uses thereof
CA3028718A1 (en)	2016-06-24	2017-12-28	Infinity Pharmaceuticals, Inc.	Combination therapies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA747912A (en) *		1966-12-06	W. Hanske Willi	Process for the production of deoxyribonuclease blocking agents and products obtained thereby
US2715123A (en) *	1951-11-15	1955-08-09	John E Hodge	Method for conducting the amadori rearrangement of n-glycosides
NL237073A (de) *	1958-03-14
JPS42400Y1 (de) *	1964-04-18	1967-01-11

1984
- 1984-10-31 US US06/666,904 patent/US4656159A/en not_active Expired - Fee Related
1985
- 1985-10-30 AT AT85307874T patent/ATE55390T1/de not_active IP Right Cessation
- 1985-10-30 EP EP85307874A patent/EP0181154B1/de not_active Expired - Lifetime
- 1985-10-30 DE DE8585307874T patent/DE3579110D1/de not_active Expired - Lifetime
- 1985-10-31 JP JP60245256A patent/JPS61118394A/ja active Granted

Also Published As

Publication number	Publication date
EP0181154A3 (en)	1988-01-27
JPS61118394A (ja)	1986-06-05
JPH0216757B2 (de)	1990-04-18
EP0181154A2 (de)	1986-05-14
DE3579110D1 (de)	1990-09-13
EP0181154B1 (de)	1990-08-08
US4656159A (en)	1987-04-07

Legal Events

Date	Code	Title	Description
1990-12-15	UEP	Publication of translation of european patent specification
1993-07-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE55390T1 (de)	1990-08-15	Senfgas-derivate der c-6-aminogalaktose und ihre verwendung.
CA2079413A1 (en)	1993-03-31	Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use
ES8800888A1 (es)	1987-12-01	Procedimiento para la preparacion de compuestos analogos in-denicos de la mevalonolactona y sus derivados
ES2135058T3 (es)	1999-10-16	Fosfito monodentado y composicion de catalizador a base de niquel para la hidrocianacion de monoolefinas.
UA6343A1 (uk)	1994-12-29	Спосіб одержання похідних 2-оксоінділ-1-карбоксаміда
IE801023L (en)	1980-11-18	Pyrimidinylamino diazacycloalkenes
FI971935A0 (fi)	1997-05-06	Polyanioniset bentsyyliglykosidit sileän lihaskudoksen solujen lisääntymisen estäjinä
ES8706163A1 (es)	1987-06-01	Procedimiento para la fabricacion de nuevos derivados nu- cleosidos
ES557061A0 (es)	1988-01-01	Un procedimiento para preparar un derivado de 1,5-benzotiazepina
GR852261B (de)	1986-01-17
ES8705425A1 (es)	1987-05-01	Un compuesto.
ES545575A0 (es)	1986-03-16	Un procedimiento para la preparacion de tiazolidinas
DK604485A (da)	1986-06-26	Carbapenemforbindelser, deres fremstilling og anvendelse
GR852813B (de)	1986-03-21
IE811037L (en)	1981-12-06	Taurine derivatives
ES8705421A1 (es)	1987-05-01	Un procedimiento para la preparacion de 4-amino-2-fenil-quinolinas
NZ217593A (en)	1988-10-28	7-aminoazolo(1,5-a pyrimidine derivatives and fungicidal compositions
IE862062L (en)	1987-02-02	Androst-5-en-17-ones
IE780008L (en)	1978-07-24	Arylenedioxy-bis-diketones
ES550059A0 (es)	1987-12-01	Un procedimiento para la preparacion de nuevos derivados de aminobenzamida.
EP0151094A3 (de)	1985-08-21	Pharmakologisch aktive Imidazopyridinverbindungen
ES8601931A1 (es)	1985-11-16	Procedimiento para preparar imidazoles y triazoles con es- tructura de enoleter
ATE75468T1 (de)	1992-05-15	Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung.
GB8500482D0 (en)	1985-02-13	Substituted phenyl ethers
ES8303400A1 (es)	1983-02-01	"procedimiento para preparar derivados de bencilazol."