ATE554084T1 - N-hydroxyacrylamidverbindungen - Google Patents

N-hydroxyacrylamidverbindungen

Info

Publication number: ATE554084T1
Authority: AT; Austria
Prior art keywords: hydroxyacrylamide; hydroxyacrylamide compounds; compounds; novel; pharmaceutically acceptable
Prior art date: 2006-02-07

Application number

AT07708338T

Other languages

English (en)

Inventor

Fumiyuki Shirai

Hideo Tsutsumi

Hiromichi Itani

Yoshihiro Kozuki

Yoshiteru Eikyu

Taro Masunaga

Original Assignee

Astellas Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-02-07

Filing date

2007-02-06

Publication date

2012-05-15

2006-02-07 Priority claimed from AU2006900588A external-priority patent/AU2006900588A0/en

2007-02-06 Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc

2012-05-15 Application granted granted Critical

2012-05-15 Publication of ATE554084T1 publication Critical patent/ATE554084T1/de

Links

HQVFKSDWNYVAQD-UHFFFAOYSA-N n-hydroxyprop-2-enamide Chemical class ONC(=O)C=C HQVFKSDWNYVAQD-UHFFFAOYSA-N 0.000 title abstract 3
150000003839 salts Chemical class 0.000 abstract 2
102000003964 Histone deacetylase Human genes 0.000 abstract 1
108090000353 Histone deacetylase Proteins 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
229940121372 histone deacetylase inhibitor Drugs 0.000 abstract 1
239000003276 histone deacetylase inhibitor Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
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- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Physical Education & Sports Medicine (AREA)
Immunology (AREA)
Hematology (AREA)
Dermatology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pulmonology (AREA)
Oncology (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Cardiology (AREA)
Ophthalmology & Optometry (AREA)
Heart & Thoracic Surgery (AREA)
Obesity (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Pain & Pain Management (AREA)
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AT07708338T 2006-02-07 2007-02-06 N-hydroxyacrylamidverbindungen ATE554084T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
AU2006900588A AU2006900588A0 (en)		2006-02-07	HDAC inhibitor
PCT/JP2007/052447 WO2007091703A1 (en)	2006-02-07	2007-02-06	N-hydroxyacrylamide compounds

Publications (1)

Publication Number	Publication Date
ATE554084T1 true ATE554084T1 (de)	2012-05-15

Family

ID=38038616

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT07708338T ATE554084T1 (de)	2006-02-07	2007-02-06	N-hydroxyacrylamidverbindungen

Country Status (19)

Country	Link
US (1)	US7750155B2 (de)
EP (1)	EP1981877B1 (de)
JP (1)	JP5218057B2 (de)
KR (1)	KR20080091297A (de)
CN (1)	CN101379059A (de)
AT (1)	ATE554084T1 (de)
AU (1)	AU2007213018A1 (de)
BR (1)	BRPI0707693A2 (de)
CA (1)	CA2641579A1 (de)
ES (1)	ES2384121T3 (de)
IL (1)	IL193252A0 (de)
MX (1)	MX2008010035A (de)
NO (1)	NO20083836L (de)
PL (1)	PL1981877T3 (de)
PT (1)	PT1981877E (de)
RU (1)	RU2008135979A (de)
TW (1)	TW200806652A (de)
WO (1)	WO2007091703A1 (de)
ZA (1)	ZA200806778B (de)

Families Citing this family (15)

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EA019033B1 (ru) *	2008-03-26	2013-12-30	Новартис Аг	Ингибиторы дезацетилазы в, основанные на гидроксамате
WO2009118370A1 (en)	2008-03-27	2009-10-01	Janssen Pharmaceutica Nv	Aza-bicyclohexyl substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase
WO2011017448A1 (en) *	2009-08-05	2011-02-10	The Trustees Of The University Of Pennsylvania	Use of histone deacetylase inhibitors for treatment of autoimmune diseases
NZ610225A (en) *	2010-11-16	2015-08-28	Acetylon Pharmaceuticals Inc	Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof
WO2015054099A1 (en)	2013-10-08	2015-04-16	Acetylon Pharmaceuticals, Inc.	Combinations of histone deacetylase inhibitors and either her2 inhibitors or pi3k inhibitors
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2007
- 2007-02-06 CN CNA2007800047171A patent/CN101379059A/zh active Pending
- 2007-02-06 WO PCT/JP2007/052447 patent/WO2007091703A1/en not_active Ceased
- 2007-02-06 PT PT07708338T patent/PT1981877E/pt unknown
- 2007-02-06 JP JP2008533306A patent/JP5218057B2/ja not_active Expired - Fee Related
- 2007-02-06 BR BRPI0707693-2A patent/BRPI0707693A2/pt not_active IP Right Cessation
- 2007-02-06 RU RU2008135979/04A patent/RU2008135979A/ru not_active Application Discontinuation
- 2007-02-06 PL PL07708338T patent/PL1981877T3/pl unknown
- 2007-02-06 US US12/278,580 patent/US7750155B2/en not_active Expired - Fee Related
- 2007-02-06 ZA ZA200806778A patent/ZA200806778B/xx unknown
- 2007-02-06 AU AU2007213018A patent/AU2007213018A1/en not_active Abandoned
- 2007-02-06 MX MX2008010035A patent/MX2008010035A/es not_active Application Discontinuation
- 2007-02-06 AT AT07708338T patent/ATE554084T1/de active
- 2007-02-06 EP EP07708338A patent/EP1981877B1/de not_active Not-in-force
- 2007-02-06 KR KR1020087021783A patent/KR20080091297A/ko not_active Withdrawn
- 2007-02-06 CA CA002641579A patent/CA2641579A1/en not_active Abandoned
- 2007-02-06 ES ES07708338T patent/ES2384121T3/es active Active
- 2007-02-07 TW TW096104449A patent/TW200806652A/zh unknown
2008
- 2008-08-05 IL IL193252A patent/IL193252A0/en unknown
- 2008-09-05 NO NO20083836A patent/NO20083836L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
PL1981877T3 (pl)	2012-12-31
IL193252A0 (en)	2009-02-11
EP1981877B1 (de)	2012-04-18
US20090054465A1 (en)	2009-02-26
MX2008010035A (es)	2008-10-17
CA2641579A1 (en)	2007-08-16
EP1981877A1 (de)	2008-10-22
NO20083836L (no)	2008-11-05
ZA200806778B (en)	2009-11-25
US7750155B2 (en)	2010-07-06
RU2008135979A (ru)	2010-03-20
CN101379059A (zh)	2009-03-04
ES2384121T3 (es)	2012-06-29
AU2007213018A1 (en)	2007-08-16
BRPI0707693A2 (pt)	2011-05-10
KR20080091297A (ko)	2008-10-09
WO2007091703A1 (en)	2007-08-16
JP5218057B2 (ja)	2013-06-26
TW200806652A (en)	2008-02-01
PT1981877E (pt)	2012-05-24
JP2009525945A (ja)	2009-07-16

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