ATE554092T1 - Azabicyclische heterocyclen als cannabinoid- rezeptormodulatoren - Google Patents
Azabicyclische heterocyclen als cannabinoid- rezeptormodulatorenInfo
- Publication number
- ATE554092T1 ATE554092T1 AT07869220T AT07869220T ATE554092T1 AT E554092 T1 ATE554092 T1 AT E554092T1 AT 07869220 T AT07869220 T AT 07869220T AT 07869220 T AT07869220 T AT 07869220T AT E554092 T1 ATE554092 T1 AT E554092T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- receptor modulators
- cannabinoid receptor
- therapeutic agents
- additional therapeutic
- Prior art date
Links
- 239000003520 cannabinoid receptor affecting agent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 2
- 229940124597 therapeutic agent Drugs 0.000 abstract 2
- 239000000556 agonist Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/02—Nasal agents, e.g. decongestants
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- A—HUMAN NECESSITIES
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Child & Adolescent Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86993306P | 2006-12-14 | 2006-12-14 | |
| PCT/US2007/087404 WO2008076810A2 (en) | 2006-12-14 | 2007-12-13 | Azabicyclic heterocycles as cannabinoid receptor modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE554092T1 true ATE554092T1 (de) | 2012-05-15 |
Family
ID=39343511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07869220T ATE554092T1 (de) | 2006-12-14 | 2007-12-13 | Azabicyclische heterocyclen als cannabinoid- rezeptormodulatoren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8030306B2 (de) |
| EP (1) | EP2094705B1 (de) |
| JP (1) | JP2010513307A (de) |
| CN (1) | CN101631789A (de) |
| AT (1) | ATE554092T1 (de) |
| ES (1) | ES2384808T3 (de) |
| NO (1) | NO20092230L (de) |
| WO (1) | WO2008076810A2 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA111640C2 (uk) | 2011-11-08 | 2016-05-25 | Ф. Хоффманн-Ля Рош Аг | ПОХІДНІ [1,2,3]ТРИАЗОЛО[4,5-d]ПІРИМІДИНУ ЯК АГОНІСТИ КАНАБІНОЇДНОГО РЕЦЕПТОРА 2 |
| AU2015341811A1 (en) | 2014-11-07 | 2017-03-30 | F. Hoffmann-La Roche Ag | Triazolo[4,5-d]pyrimidines as agonists of the cannabinoid receptor 2 |
| US20210393621A1 (en) | 2018-10-26 | 2021-12-23 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1697371T3 (da) * | 2003-12-19 | 2007-09-17 | Bristol Myers Squibb Co | Azabicykliske heterocykliske forbindelser som cannabinoidreceptormodulatorer |
| CN101084211A (zh) * | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 杂环衍生物及其作为治疗剂的用途 |
| US7629342B2 (en) * | 2005-06-17 | 2009-12-08 | Bristol-Myers Squibb Company | Azabicyclic heterocycles as cannabinoid receptor modulators |
| WO2009048544A1 (en) * | 2007-10-10 | 2009-04-16 | Merck & Co., Inc. | Liquid pharmaceutical compositions for parenteral administration of a substituted amide |
-
2007
- 2007-12-13 WO PCT/US2007/087404 patent/WO2008076810A2/en not_active Ceased
- 2007-12-13 JP JP2009541587A patent/JP2010513307A/ja not_active Withdrawn
- 2007-12-13 AT AT07869220T patent/ATE554092T1/de active
- 2007-12-13 ES ES07869220T patent/ES2384808T3/es active Active
- 2007-12-13 US US12/518,707 patent/US8030306B2/en active Active
- 2007-12-13 CN CN200780051308A patent/CN101631789A/zh active Pending
- 2007-12-13 EP EP07869220A patent/EP2094705B1/de active Active
-
2009
- 2009-06-10 NO NO20092230A patent/NO20092230L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2094705A2 (de) | 2009-09-02 |
| NO20092230L (no) | 2009-07-13 |
| US20100029656A1 (en) | 2010-02-04 |
| JP2010513307A (ja) | 2010-04-30 |
| WO2008076810A9 (en) | 2009-07-30 |
| ES2384808T3 (es) | 2012-07-12 |
| WO2008076810A3 (en) | 2008-08-14 |
| US8030306B2 (en) | 2011-10-04 |
| EP2094705B1 (de) | 2012-04-18 |
| WO2008076810A2 (en) | 2008-06-26 |
| CN101631789A (zh) | 2010-01-20 |
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