ATE554770T1 - Therapeutisches mittel gegen entzündliche darmerkrankungen - Google Patents
Therapeutisches mittel gegen entzündliche darmerkrankungenInfo
- Publication number
- ATE554770T1 ATE554770T1 AT07737060T AT07737060T ATE554770T1 AT E554770 T1 ATE554770 T1 AT E554770T1 AT 07737060 T AT07737060 T AT 07737060T AT 07737060 T AT07737060 T AT 07737060T AT E554770 T1 ATE554770 T1 AT E554770T1
- Authority
- AT
- Austria
- Prior art keywords
- inflammatory bowel
- bowel disease
- therapeutic agent
- agent against
- against inflammatory
- Prior art date
Links
- 208000022559 Inflammatory bowel disease Diseases 0.000 title abstract 4
- 239000003814 drug Substances 0.000 title abstract 3
- 229940124597 therapeutic agent Drugs 0.000 title abstract 3
- WUBBRNOQWQTFEX-UHFFFAOYSA-N 4-aminosalicylic acid Chemical compound NC1=CC=C(C(O)=O)C(O)=C1 WUBBRNOQWQTFEX-UHFFFAOYSA-N 0.000 abstract 1
- 206010009900 Colitis ulcerative Diseases 0.000 abstract 1
- 208000011231 Crohn disease Diseases 0.000 abstract 1
- 201000006704 Ulcerative Colitis Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 229960004909 aminosalicylic acid Drugs 0.000 abstract 1
- 230000001142 anti-diarrhea Effects 0.000 abstract 1
- 208000037976 chronic inflammation Diseases 0.000 abstract 1
- 230000006020 chronic inflammation Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- QQHMKNYGKVVGCZ-UHFFFAOYSA-N tipiracil Chemical compound N1C(=O)NC(=O)C(Cl)=C1CN1C(=N)CCC1 QQHMKNYGKVVGCZ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006110869 | 2006-04-13 | ||
| PCT/JP2007/000403 WO2007122812A1 (ja) | 2006-04-13 | 2007-04-12 | 炎症性腸疾患治療薬 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE554770T1 true ATE554770T1 (de) | 2012-05-15 |
Family
ID=38624731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07737060T ATE554770T1 (de) | 2006-04-13 | 2007-04-12 | Therapeutisches mittel gegen entzündliche darmerkrankungen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7820686B2 (de) |
| EP (1) | EP2005962B1 (de) |
| JP (1) | JP5058156B2 (de) |
| KR (1) | KR101390144B1 (de) |
| CN (1) | CN101420957B (de) |
| AT (1) | ATE554770T1 (de) |
| AU (1) | AU2007242332B2 (de) |
| CA (1) | CA2649256C (de) |
| ES (1) | ES2382673T3 (de) |
| TW (1) | TWI406858B (de) |
| WO (1) | WO2007122812A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI435725B (zh) * | 2007-10-11 | 2014-05-01 | Taiho Pharmaceutical Co Ltd | The use of a uracil compound for a prophylactic or therapeutic composition for the preparation of cystitis and hepatitis |
| TWI429439B (zh) * | 2007-10-11 | 2014-03-11 | Taiho Pharmaceutical Co Ltd | And a therapeutic agent for inflammatory bowel disease using a uracil derivative as an active ingredient |
| TWI503122B (zh) * | 2012-02-15 | 2015-10-11 | Taiho Pharmaceutical Co Ltd | Oral administration of pharmaceutical compositions |
| CN102920789A (zh) * | 2012-11-29 | 2013-02-13 | 中央民族大学 | 治疗溃疡性结肠炎的药物制剂蒙药嘎日迪及其制备方法 |
| DK3012255T3 (da) | 2013-06-17 | 2021-12-06 | Taiho Pharmaceutical Co Ltd | Stabil krystalform af tipiracilhydrochlorid og krystalliseringsfremgangsmåde dertil |
| US11896564B2 (en) * | 2018-08-15 | 2024-02-13 | Pharmacyl Ab | Medical treatment for pathologic inflammation |
| WO2020072645A1 (en) * | 2018-10-03 | 2020-04-09 | Akebia Therapeutics, Inc. | Benzimidazole derivative for use in the treatment of inflammatory disorders |
| CN110638803A (zh) * | 2019-10-24 | 2020-01-03 | 上海长海医院 | Dencichine在制备治疗炎性肠病药物中的用途 |
| AU2020386913A1 (en) * | 2019-11-20 | 2022-06-02 | Angion Biomedica Corp. | Methods for treating inflammatory bowel disease |
| CN111686106B (zh) * | 2020-04-05 | 2022-07-15 | 温州医科大学附属第一医院 | 提高Dicer表达的化合物在制备药物中的应用 |
| WO2022047730A1 (en) * | 2020-09-04 | 2022-03-10 | Shanghai Pharmaceuticals Holding Co., Ltd. | Methods to treat inflammatory bowel disease |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69629156T2 (de) * | 1995-03-29 | 2004-05-06 | Taiho Pharmaceutical Co. Ltd. | Uracilderivate und diese enthaltende antitumoreffekt-verstärker sowie antitumormittel |
| JP3746522B2 (ja) * | 1996-04-05 | 2006-02-15 | 麒麟麦酒株式会社 | イネ科植物の発芽種子由来のタンパク質および不溶性食物センイを含有する物質並びにその用途 |
| US6255314B1 (en) * | 1996-09-24 | 2001-07-03 | Taiho Charmaceutical Co., Ltd. | Cancerous metastasis inhibitors containing uracil derivatives |
| JP4049477B2 (ja) * | 1999-03-23 | 2008-02-20 | 大鵬薬品工業株式会社 | 副作用軽減剤 |
-
2007
- 2007-04-12 CA CA2649256A patent/CA2649256C/en not_active Expired - Fee Related
- 2007-04-12 KR KR1020087023029A patent/KR101390144B1/ko not_active Expired - Fee Related
- 2007-04-12 TW TW096112890A patent/TWI406858B/zh not_active IP Right Cessation
- 2007-04-12 JP JP2008511965A patent/JP5058156B2/ja not_active Expired - Fee Related
- 2007-04-12 US US12/296,671 patent/US7820686B2/en not_active Expired - Fee Related
- 2007-04-12 EP EP07737060A patent/EP2005962B1/de active Active
- 2007-04-12 WO PCT/JP2007/000403 patent/WO2007122812A1/ja not_active Ceased
- 2007-04-12 ES ES07737060T patent/ES2382673T3/es active Active
- 2007-04-12 AT AT07737060T patent/ATE554770T1/de active
- 2007-04-12 CN CN2007800133586A patent/CN101420957B/zh not_active Expired - Fee Related
- 2007-04-12 AU AU2007242332A patent/AU2007242332B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US20090209565A1 (en) | 2009-08-20 |
| KR20080108999A (ko) | 2008-12-16 |
| EP2005962A9 (de) | 2009-07-15 |
| HK1127964A1 (en) | 2009-10-09 |
| CA2649256A1 (en) | 2007-11-01 |
| TW200813025A (en) | 2008-03-16 |
| CN101420957B (zh) | 2011-04-13 |
| AU2007242332B2 (en) | 2012-02-02 |
| EP2005962B1 (de) | 2012-04-25 |
| CA2649256C (en) | 2013-09-10 |
| ES2382673T3 (es) | 2012-06-12 |
| JP5058156B2 (ja) | 2012-10-24 |
| TWI406858B (zh) | 2013-09-01 |
| JPWO2007122812A1 (ja) | 2009-09-03 |
| KR101390144B1 (ko) | 2014-04-28 |
| AU2007242332A1 (en) | 2007-11-01 |
| WO2007122812A1 (ja) | 2007-11-01 |
| US7820686B2 (en) | 2010-10-26 |
| CN101420957A (zh) | 2009-04-29 |
| EP2005962A4 (de) | 2009-09-23 |
| EP2005962A2 (de) | 2008-12-24 |
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