ATE555187T1 - Ophthalmische zusammensetzung mit hyaluronsäure - Google Patents
Ophthalmische zusammensetzung mit hyaluronsäureInfo
- Publication number
- ATE555187T1 ATE555187T1 AT08770623T AT08770623T ATE555187T1 AT E555187 T1 ATE555187 T1 AT E555187T1 AT 08770623 T AT08770623 T AT 08770623T AT 08770623 T AT08770623 T AT 08770623T AT E555187 T1 ATE555187 T1 AT E555187T1
- Authority
- AT
- Austria
- Prior art keywords
- hyaluronic acid
- composition
- ophthalmic composition
- ppm
- poly
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title abstract 3
- 229920002674 hyaluronan Polymers 0.000 title abstract 3
- 229960003160 hyaluronic acid Drugs 0.000 title abstract 3
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000004140 cleaning Methods 0.000 abstract 1
- 230000000249 desinfective effect Effects 0.000 abstract 1
- 238000004806 packaging method and process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/88—Ampholytes; Electroneutral compounds
- C11D1/90—Betaines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
- A61L12/141—Biguanides, e.g. chlorhexidine
- A61L12/142—Polymeric biguanides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/88—Ampholytes; Electroneutral compounds
- C11D1/92—Sulfobetaines ; Sulfitobetaines
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/0005—Other compounding ingredients characterised by their effect
- C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/22—Carbohydrates or derivatives thereof
- C11D3/222—Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/22—Carbohydrates or derivatives thereof
- C11D3/222—Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin
- C11D3/227—Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin with nitrogen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/37—Polymers
- C11D3/3703—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- C11D3/3723—Polyamines or polyalkyleneimines
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Preparation (AREA)
- Eyeglasses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94362007P | 2007-06-13 | 2007-06-13 | |
| US12/131,549 US20080311070A1 (en) | 2007-06-13 | 2008-06-02 | Ophthalmic composition with hyaluronic acid |
| PCT/US2008/066464 WO2008157140A1 (en) | 2007-06-13 | 2008-06-11 | Ophthalmic composition with hyaluronic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE555187T1 true ATE555187T1 (de) | 2012-05-15 |
Family
ID=40132537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08770623T ATE555187T1 (de) | 2007-06-13 | 2008-06-11 | Ophthalmische zusammensetzung mit hyaluronsäure |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US8759321B2 (de) |
| EP (1) | EP2171025B1 (de) |
| AT (1) | ATE555187T1 (de) |
| WO (1) | WO2008157140A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8759321B2 (en) | 2007-06-13 | 2014-06-24 | Bausch & Lomb Incorporated | Ophthalmic composition with hyaluronic acid and polymeric biguanide |
| US9096819B2 (en) | 2008-01-31 | 2015-08-04 | Bausch & Lomb Incorporated | Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer |
| US8119112B2 (en) * | 2008-01-31 | 2012-02-21 | Bausch & Lomb Incorporated | Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid |
| TWI454289B (zh) * | 2008-04-03 | 2014-10-01 | Alcon Res Ltd | 使用順式二醇的聚合物於抑制陽離子殺生物劑被吸收進入水凝膠生物材質中之用途 |
| US20100086512A1 (en) * | 2008-10-02 | 2010-04-08 | Rolf Schaefer | Mucomimetic compositions and uses therefore |
| US8501200B2 (en) * | 2010-04-26 | 2013-08-06 | Bausch & Lomb Incorporated | Ophthalmic compositions with biguanide and PEG-glycerol esters |
| CN102675651B (zh) * | 2012-04-20 | 2014-06-04 | 常州华联保健敷料有限公司 | 抗菌敷料用壳聚糖水凝胶的制备方法 |
| US9248928B2 (en) * | 2012-12-21 | 2016-02-02 | Coopervision International Holding Company, Lp | Methods of manufacturing contact lenses for delivery of beneficial agents |
| US10245324B2 (en) | 2014-10-31 | 2019-04-02 | Johnson & Johnson Consumer Inc. | Ophthalmic composition |
| CN110121548A (zh) | 2017-01-03 | 2019-08-13 | 陈煌兴 | 支化聚合双胍化合物及其用途 |
| TW201915519A (zh) * | 2017-09-26 | 2019-04-16 | 鴻海精密工業股份有限公司 | 透氣性眼用鏡片材料及透氣性眼用鏡片 |
| GB201813229D0 (en) | 2018-08-14 | 2018-09-26 | Ocutec Ltd | Formulation |
| CN113366025A (zh) * | 2019-01-30 | 2021-09-07 | 鲍希与洛姆伯股份有限公司 | 交联的聚合物网络及其用途 |
| CN110078913B (zh) * | 2019-05-29 | 2021-08-24 | 湖南雪天精细化工股份有限公司 | 一种聚六亚甲基双胍盐酸盐的制备方法 |
| CN111773241A (zh) * | 2020-07-21 | 2020-10-16 | 贵州威克斯医疗科技有限公司 | 一种含有phmb用于预防及缓解尿布湿疹的组合物 |
| WO2022189548A1 (en) | 2021-03-10 | 2022-09-15 | Bausch + Lomb Ireland Limited | Contact lens treating solution |
| US12357594B1 (en) | 2021-06-30 | 2025-07-15 | Sage Products, Llc | Antimicrobial solution for pre-operative preparation |
| CN113908171B (zh) * | 2021-09-09 | 2024-01-30 | 南京睿远医疗技术有限公司 | 一种眼用润滑液组合物及其应用 |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US555910A (en) | 1896-03-03 | George ii | ||
| GB1152243A (en) * | 1965-11-26 | 1969-05-14 | Ici Ltd | Process for the Manufacture of Polymeric Diguanides |
| US4141973A (en) | 1975-10-17 | 1979-02-27 | Biotrics, Inc. | Ultrapure hyaluronic acid and the use thereof |
| US5166331A (en) | 1983-10-10 | 1992-11-24 | Fidia, S.P.A. | Hyaluronics acid fractions, methods for the preparation thereof, and pharmaceutical compositions containing same |
| IT1212892B (it) | 1983-10-11 | 1989-11-30 | Della Valle Francesco | Acido ialuronico ottenuto per mezzodi filtrazione molecolare sprovvisto di attivita' infiammatoria e sua utilizzazione terapeutica |
| US5316926A (en) | 1983-11-25 | 1994-05-31 | Miles Inc. | Method for the microbiological production of non-antigenic hyaluronic acid |
| US4758595A (en) | 1984-12-11 | 1988-07-19 | Bausch & Lomb Incorporated | Disinfecting and preserving systems and methods of use |
| US5409904A (en) * | 1984-11-13 | 1995-04-25 | Alcon Laboratories, Inc. | Hyaluronic acid compositions and methods |
| US4784990A (en) * | 1985-01-18 | 1988-11-15 | Bio-Technology General Corporation | High molecular weight sodium hyaluronate |
| US5099013A (en) | 1985-03-12 | 1992-03-24 | Biomatrix, Inc, | Hylan preparation and method of recovery thereof from animal tissues |
| US4746504A (en) * | 1986-03-14 | 1988-05-24 | Bio-Technology General Corp. | Heavy metal salts of hyaluronic acid and their use as antimicrobial agents |
| US5461081A (en) * | 1989-09-28 | 1995-10-24 | Alcon Laboratories, Inc. | Topical ophthalmic pharmaceutical vehicles |
| GB9024223D0 (en) | 1990-11-07 | 1990-12-19 | Fermentech Ltd | Production of hyaluronic acid |
| IT1247175B (it) * | 1991-04-19 | 1994-12-12 | Fidia Spa | Procedimento per la purificazione di acido ialuronico e frazione di acido ialuronico puro per uso oftalmico. |
| US5358706A (en) | 1992-09-30 | 1994-10-25 | Union Carbide Chemicals & Plastics Technology Corporation | Muco-adhesive polymers |
| IT1263394B (it) * | 1993-07-30 | 1996-08-05 | Fidia Advanced Biopolymers Srl | Composizioni farmaceutiche per uso topico a base di acido ialuronico e suoi derivati |
| IT1273011B (it) | 1994-07-25 | 1997-07-01 | Trhecnopharma S A | Preparato oftalmico per l'uso come lacrima artificiale |
| US5476614A (en) * | 1995-01-17 | 1995-12-19 | Colgate Palmolive Co. | High foaming nonionic surfactant based liquid detergent |
| US5683993A (en) | 1995-06-22 | 1997-11-04 | Ciba Vision Corporation | Compositions and methods for stabilizing polymers |
| KR0154371B1 (ko) | 1995-08-01 | 1998-11-16 | 이병언 | 콘텍트렌즈 세정액조성물 |
| ES2219751T3 (es) | 1996-01-30 | 2004-12-01 | BAUSCH & LOMB INCORPORATED | Tratamiento de lentes de contacto con una solucion acuosa que incluye compuestos de sulfobetaina. |
| EP0938903A4 (de) * | 1996-02-07 | 2000-11-15 | Rohto Pharma | Ophthalmische zusammensetzung mit regulierter viskosität |
| US5858346A (en) | 1997-05-09 | 1999-01-12 | Allergan | Compositions and methods for enhancing contact lens wearability |
| US6277365B1 (en) | 1997-09-18 | 2001-08-21 | Bausch & Lomb Incorporated | Ophthalmic composition including a cationic glycoside and an anionic therapeutic agent |
| US5965088A (en) * | 1997-10-23 | 1999-10-12 | Lever; Andrea M. | Method for providing rapid disinfection of contact lenses |
| AU737541B2 (en) * | 1997-11-12 | 2001-08-23 | Bausch & Lomb Incorporated | Disinfecting contact lenses with polyquaterniums and polymeric biguanides |
| US6080714A (en) | 1997-11-20 | 2000-06-27 | Akzo Nobel Nv | Solid composition comprising an amphoteric surfactant, a process for its preparation, and the use thereof |
| ZA9811445B (en) * | 1997-12-19 | 1999-08-16 | Alcon Lab Inc | Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions. |
| JP3883739B2 (ja) * | 1998-05-22 | 2007-02-21 | 株式会社メニコン | コンタクトレンズ用殺菌液 |
| US20020057417A1 (en) * | 1999-02-19 | 2002-05-16 | Galin Miles A. | Polysaccharide coating of contact lenses |
| IT1306123B1 (it) | 1999-04-02 | 2001-05-30 | Technopharma Sa | Soluzione oftalmica viscosizzata con azione detergente sulle lenti acontatto. |
| DE19961621C2 (de) * | 1999-12-13 | 2002-11-14 | Schuelke & Mayr Gmbh | Bakterizide und fungizide flüssige Zubereitungen für technische Produkte |
| KR100354606B1 (ko) | 2000-02-01 | 2002-09-30 | 주식회사 중외제약 | 다목적 콘택트 렌즈 관리 용액 조성물 |
| US6569824B2 (en) * | 2000-02-16 | 2003-05-27 | Novartis Ag | Contact lens treating method and composition |
| US20020039975A1 (en) * | 2000-07-31 | 2002-04-04 | Stone Ralph P. | Simplified process for cleaning and disinfecting contact lenses with a single solution |
| TW586945B (en) | 2001-01-12 | 2004-05-11 | Novartis Ag | Lens care product containing dexpanthenol |
| GB0130603D0 (en) | 2001-12-20 | 2002-02-06 | Renaissance Healthcare Europ L | Improvements in or relating to ophthalmic solutions |
| CA2443472A1 (en) * | 2002-02-07 | 2003-08-14 | Ophtecs Corporation | Liquid formulation for contact lenses |
| WO2003088914A2 (en) * | 2002-04-18 | 2003-10-30 | The University Of Iowa Research Foundation | Methods of inhibiting and treating bacterial biofilms by metal chelators |
| US20040063591A1 (en) | 2002-09-30 | 2004-04-01 | Bausch & Lomb Incorporated | Compositions with enhanced antimicrobial efficacy against acanthamoebae |
| TWI322828B (en) | 2002-12-23 | 2010-04-01 | Alcon Inc | Use of multifunctional surface active agents to clean contact lenses |
| US20040137079A1 (en) | 2003-01-08 | 2004-07-15 | Cook James N. | Contact lens and eye drop rewetter compositions and methods |
| US20050196370A1 (en) | 2003-03-18 | 2005-09-08 | Zhi-Jian Yu | Stable ophthalmic oil-in-water emulsions with sodium hyaluronate for alleviating dry eye |
| CA2527712C (en) | 2003-06-13 | 2014-08-05 | Alcon, Inc. | Ophthalmic compositions containing a synergistic combination of two polymers |
| US6930077B2 (en) | 2003-09-10 | 2005-08-16 | Advanced Medical Optics, Inc. | Compositions and methods using sub-PPM combinations of polyquaternium-1 and high molecular weight PHMB |
| US7578996B2 (en) | 2004-04-07 | 2009-08-25 | Advanced Medical Optics, Inc. | Cetylpyridinium chloride as an antimicrobial agent in ophthalmic compositions |
| JP2008519846A (ja) | 2004-11-09 | 2008-06-12 | アドバンスト メディカル オプティクス, インコーポレーテッド | 眼科用溶液 |
| JP4247546B2 (ja) | 2005-07-07 | 2009-04-02 | ロート製薬株式会社 | 多糖含有コンタクトレンズ用液剤 |
| CA2621604A1 (en) | 2005-09-07 | 2007-03-15 | Amo Regional Holdings | Bi-modal hyaluronate solution |
| US7670997B2 (en) | 2006-06-08 | 2010-03-02 | Bausch & Lomb Incorporated | Ophthalmic compositions comprising a branched, glycerol monoalkyl compound and a fatty acid monoester |
| US8138156B2 (en) | 2006-10-18 | 2012-03-20 | Bausch & Lomb Incorporated | Ophthalmic compositions containing diglycine |
| US8759321B2 (en) | 2007-06-13 | 2014-06-24 | Bausch & Lomb Incorporated | Ophthalmic composition with hyaluronic acid and polymeric biguanide |
-
2008
- 2008-04-25 US US12/109,599 patent/US8759321B2/en active Active
- 2008-06-02 US US12/131,549 patent/US20080311070A1/en not_active Abandoned
- 2008-06-11 AT AT08770623T patent/ATE555187T1/de active
- 2008-06-11 EP EP08770623A patent/EP2171025B1/de active Active
- 2008-06-11 WO PCT/US2008/066464 patent/WO2008157140A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US20080312182A1 (en) | 2008-12-18 |
| WO2008157140A1 (en) | 2008-12-24 |
| US20080311070A1 (en) | 2008-12-18 |
| US8759321B2 (en) | 2014-06-24 |
| EP2171025A1 (de) | 2010-04-07 |
| EP2171025B1 (de) | 2012-04-25 |
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