ATE555666T1 - Einfang, konzentration und quantifizierung eines abnormalen prionproteins aus biologischen flüssigkeiten mittels tiefenfiltration - Google Patents

Einfang, konzentration und quantifizierung eines abnormalen prionproteins aus biologischen flüssigkeiten mittels tiefenfiltration

Info

Publication number
ATE555666T1
ATE555666T1 AT03731344T AT03731344T ATE555666T1 AT E555666 T1 ATE555666 T1 AT E555666T1 AT 03731344 T AT03731344 T AT 03731344T AT 03731344 T AT03731344 T AT 03731344T AT E555666 T1 ATE555666 T1 AT E555666T1
Authority
AT
Austria
Prior art keywords
prion protein
capture
quantification
concentration
biological fluid
Prior art date
Application number
AT03731344T
Other languages
English (en)
Inventor
Holten Robert Van
Stephen Autenrieth
Original Assignee
Ortho Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29586988&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE555666(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ortho Clinical Diagnostics Inc filed Critical Ortho Clinical Diagnostics Inc
Application granted granted Critical
Publication of ATE555666T1 publication Critical patent/ATE555666T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00Working-up of proteins for foodstuffs
    • A23J3/04Animal proteins
    • A23J3/12Animal proteins from blood
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L5/00Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/20Removal of unwanted matter, e.g. deodorisation or detoxification
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L5/00Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/20Removal of unwanted matter, e.g. deodorisation or detoxification
    • A23L5/23Removal of unwanted matter, e.g. deodorisation or detoxification by extraction with solvents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/022Filtration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05Living organisms or biological materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Water Supply & Treatment (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • External Artificial Organs (AREA)
AT03731344T 2002-05-23 2003-05-23 Einfang, konzentration und quantifizierung eines abnormalen prionproteins aus biologischen flüssigkeiten mittels tiefenfiltration ATE555666T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38318002P 2002-05-23 2002-05-23
US10/444,606 US7201901B2 (en) 2002-05-23 2003-05-23 Capture, concentration and quantitation of abnormal prion protein from biological fluids using depth filtration
PCT/US2003/016347 WO2003100080A2 (en) 2002-05-23 2003-05-23 Capture, concentration and quantitation of abnormal prion protein from biological fluids using depth filtration

Publications (1)

Publication Number Publication Date
ATE555666T1 true ATE555666T1 (de) 2012-05-15

Family

ID=29586988

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03731344T ATE555666T1 (de) 2002-05-23 2003-05-23 Einfang, konzentration und quantifizierung eines abnormalen prionproteins aus biologischen flüssigkeiten mittels tiefenfiltration

Country Status (8)

Country Link
US (2) US7201901B2 (de)
EP (1) EP1511391B1 (de)
KR (1) KR101239818B1 (de)
CN (1) CN100507567C (de)
AT (1) ATE555666T1 (de)
AU (1) AU2003241596B2 (de)
CA (1) CA2487072A1 (de)
WO (1) WO2003100080A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA06008435A (es) * 2004-01-30 2007-05-23 Suomen Punainen Risti Veripalvelu Proceso de manufactura de una inmunoglobulina libre de virus.
ITMI20040891A1 (it) * 2004-05-04 2004-08-04 Ibsa Inst Biochimique Sa Nuovo metodo per la partizione ed inattivazione di contaminanti virali e prionici
AU2005229674B2 (en) * 2004-11-18 2010-11-04 Kedrion Melville Inc. Low concentration solvent/detergent process of immuneglobulin with pre-treatment
US7531632B2 (en) * 2006-02-16 2009-05-12 Gtc Biotherapeutics, Inc. Clarification of transgenic milk using depth filtration
CN102460167B (zh) 2009-04-15 2015-07-22 阿布拉科斯生物科学有限公司 不含朊病毒的纳米颗粒组合物和方法
CA2815342A1 (en) * 2010-10-20 2012-04-26 Medimmune, Llc Methods for processing inclusion bodies
CN102675414A (zh) * 2011-03-08 2012-09-19 上海天伟生物制药有限公司 糖蛋白中去除/灭活朊病毒的方法
US9534037B2 (en) 2011-08-02 2017-01-03 Baxalta GmbH Systems and methods to increase protein yield from recombinant manufacturing processes
ES2556004T3 (es) 2011-12-20 2016-01-12 Novozymes A/S Método para la eliminación de virus en una solución de proteína
GB201318840D0 (en) * 2013-10-24 2013-12-11 Univ Leeds Method and device for protein preparation
IT201600079328A1 (it) * 2016-07-28 2018-01-28 Altergon Sa Metodo migliorato per la decontaminazione di materiale biologico mediante partizione e inattivazione
DE102016123458B3 (de) * 2016-12-05 2018-03-15 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Verfahren zur Herstellung transparenter biologischer Präparate für eine lichtmikroskopische Untersuchung
US11110227B2 (en) 2018-11-09 2021-09-07 Cheryl Muise Method and apparatus for injecting fluids
CN114981286B (zh) * 2019-05-03 2026-02-13 豪夫迈·罗氏有限公司 降低从纯化平台获得的组合物中酶水解活性速率的方法
EP4090666A1 (de) 2020-01-15 2022-11-23 F. Hoffmann-La Roche AG Verfahren zur verringerung von verunreinigungen aus herstellungsverfahren für rekombinante proteine

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2390074A (en) 1942-02-09 1945-12-04 Research Corp Protein product and process
US3449314A (en) 1966-06-03 1969-06-10 Ortho Pharma Corp Preparation of anti-rh globulin from human plasma
US3916026A (en) 1968-09-19 1975-10-28 Biotest Serum Institut Gmbh Method for the preparation of gamma-globulin suitable for intravenous use
US4021540A (en) 1975-07-28 1977-05-03 Ortho Diagnostics Inc. Preparation of a hepatitis B immune globulin and use thereof as a prophylactic material
US4859340A (en) 1976-03-15 1989-08-22 Cuno, Incorporated Filter sheet
US4115101A (en) * 1976-05-24 1978-09-19 Rohm And Haas Company 1-Aryl-4-pyridones
DE2624373C2 (de) 1976-05-31 1983-02-03 Arnold Dr. 8782 Karlstadt Seufert Verfahren zur Herstellung von steril filtriertem Kryopräzipilat mit einer Anreicherung des Faktors VIII
JPS6077768A (ja) * 1983-10-06 1985-05-02 テルモ株式会社 液体濾過装置
US4590002A (en) 1984-12-10 1986-05-20 Ortho Diagnostic Systems, Inc. Methods for preparation of highly purified, gamma globulins free of hepatitis-B-virus infectivity
DE3641115A1 (de) 1986-12-02 1988-06-16 Lentia Gmbh Verfahren zur herstellung eines intravenoes anwendbaren und in fluessiger form stabilen immunglobulins
US5115101A (en) 1988-06-08 1992-05-19 Miles Inc. Removal of protein A from antibody preparations
FR2639645B1 (fr) 1988-11-25 1992-05-29 Elf Aquitaine Solutions liquides concentrees de polysaccharides
AT408191B (de) * 1991-08-19 2001-09-25 Haemosan Erzeugung Pharmazeuti Verfahren zur inaktivierung von prionen
DE4137996A1 (de) 1991-11-19 1993-05-27 Behringwerke Ag Verfahren zur herstellung eines virussicheren thrombinkonzentrates
SE9500724D0 (sv) 1994-06-23 1995-02-24 Pharmacia Ab Filtrering
US6129934A (en) * 1995-06-07 2000-10-10 Ony, Inc. Modification of animal lung surfactant for treating respiratory disease due to lung surfactant deficiency or dysfunction
EP2095873A1 (de) 1996-08-30 2009-09-02 Upfront Chromatography A/S Isolierung von Immunglobulinen
US5858641A (en) 1996-09-17 1999-01-12 Shanbrom Technologies, Llc Disinfectant dye removal from blood and blood fractions using a porous poly(vinyl alcohol-acetal) copolymer
US6221614B1 (en) 1997-02-21 2001-04-24 The Regents Of The University Of California Removal of prions from blood, plasma and other liquids
AT407159B (de) * 1997-06-13 2001-01-25 Immuno Ag Verfahren zur abreicherung von viralen und molekularen pathogenen aus einem biologischen material
US6096872A (en) 1997-10-14 2000-08-01 Ortho Diagnostic Systems, Inc. Viral clearance process
JP4524045B2 (ja) 1999-01-19 2010-08-11 コモン サーヴィシス エージェンシー 蛋白質含有液体の処理
US6166187A (en) 1999-03-05 2000-12-26 The Regents Of The University Of California Method of concentrating prion proteins in blood samples
US6270672B1 (en) * 1999-08-06 2001-08-07 Baxter Aktiengesellschaft Devices and methods for removing pathogens from biological fluids
DK1206961T3 (da) * 1999-08-20 2007-04-02 Asahi Kasei Medical Co Ltd Filtermembraner til fysiologisk aktive stoffer
AU784808B2 (en) * 2001-04-02 2006-06-29 Kedrion Melville Inc. Prion and viral clearance process

Also Published As

Publication number Publication date
EP1511391B1 (de) 2012-05-02
KR101239818B1 (ko) 2013-03-07
WO2003100080A3 (en) 2004-11-11
CA2487072A1 (en) 2003-12-04
EP1511391A2 (de) 2005-03-09
US20070148685A1 (en) 2007-06-28
WO2003100080A2 (en) 2003-12-04
KR20050037509A (ko) 2005-04-22
AU2003241596A1 (en) 2003-12-12
US20040033224A1 (en) 2004-02-19
AU2003241596B2 (en) 2010-01-21
EP1511391A4 (de) 2007-05-02
CN1671293A (zh) 2005-09-21
US7201901B2 (en) 2007-04-10
CN100507567C (zh) 2009-07-01

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