ATE555803T1 - Verwendung von osteopontin zur behandlung und/oder vorbeugung von neurologischen erkrankungen - Google Patents

Verwendung von osteopontin zur behandlung und/oder vorbeugung von neurologischen erkrankungen

Info

Publication number
ATE555803T1
ATE555803T1 AT02738042T AT02738042T ATE555803T1 AT E555803 T1 ATE555803 T1 AT E555803T1 AT 02738042 T AT02738042 T AT 02738042T AT 02738042 T AT02738042 T AT 02738042T AT E555803 T1 ATE555803 T1 AT E555803T1
Authority
AT
Austria
Prior art keywords
osteopontin
treat
neurological diseases
prevent neurological
prevent
Prior art date
Application number
AT02738042T
Other languages
English (en)
Inventor
Ursula Boschert
Georg Feger
Raghuram Selvaraju
Ruben Papoian
Lilia Bernasconi
Original Assignee
Merck Serono Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Serono Sa filed Critical Merck Serono Sa
Application granted granted Critical
Publication of ATE555803T1 publication Critical patent/ATE555803T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Psychology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
AT02738042T 2001-05-17 2002-05-08 Verwendung von osteopontin zur behandlung und/oder vorbeugung von neurologischen erkrankungen ATE555803T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01111296 2001-05-17
PCT/EP2002/005081 WO2002092122A2 (en) 2001-05-17 2002-05-08 Use of osteopontin for the treatment and/or prevention of neurologic diseases

Publications (1)

Publication Number Publication Date
ATE555803T1 true ATE555803T1 (de) 2012-05-15

Family

ID=8177366

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02738042T ATE555803T1 (de) 2001-05-17 2002-05-08 Verwendung von osteopontin zur behandlung und/oder vorbeugung von neurologischen erkrankungen

Country Status (26)

Country Link
US (4) US7217687B2 (de)
EP (1) EP1389130B1 (de)
JP (2) JP4417632B2 (de)
KR (1) KR100947424B1 (de)
CN (2) CN1939538A (de)
AT (1) ATE555803T1 (de)
AU (1) AU2002312886B2 (de)
BG (1) BG108337A (de)
BR (1) BR0209812A (de)
CA (1) CA2443964A1 (de)
CZ (1) CZ20033109A3 (de)
EA (1) EA006655B1 (de)
EE (1) EE200300559A (de)
ES (1) ES2387082T3 (de)
HR (1) HRP20030840A2 (de)
HU (1) HUP0400005A3 (de)
IL (2) IL158867A0 (de)
MX (1) MXPA03010327A (de)
NO (1) NO20035025L (de)
NZ (1) NZ528852A (de)
PL (1) PL211763B1 (de)
SK (1) SK14232003A3 (de)
UA (1) UA85368C2 (de)
WO (1) WO2002092122A2 (de)
YU (1) YU89503A (de)
ZA (1) ZA200307956B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7202044B2 (en) 2001-05-09 2007-04-10 Biovision Ag Method for detecting a progressive, chronic dementia disease, and corresponding peptides and detection agents
AU2002357748A1 (en) * 2001-11-21 2003-06-10 The Board Of Trustees Of The Leland Stanford Junior University Osteopontin-related compositions and methods
AU2003278205B2 (en) * 2002-06-25 2008-01-24 Aventis Pharmaceuticals Inc. Osteopontin, oligodendrocytes and myelination
WO2004013311A2 (en) * 2002-08-06 2004-02-12 Diadexus, Inc. Compositions and methods relating to ovarian specific genes and proteins
EP1610810A2 (de) * 2003-03-28 2006-01-04 Applied Research Systems ARS Holding N.V. Verwendung von clusterin zur behandlung und/oder vorbeugung von peripherischen neurologischen erkrankungen
EP1667537B1 (de) * 2003-09-18 2013-11-06 Arla Foods Amba Fertignahrung für kleinkinder
CA2546077C (en) * 2003-11-12 2016-07-05 Yeda Research And Development Co. Ltd. Vaccine and method for treatment of neurodegenerative diseases
EP1848453B1 (de) * 2005-02-18 2010-10-27 Proximagen Ltd. Behandlung von neurodegeneration
US20060264371A1 (en) * 2005-02-18 2006-11-23 Proximagen Ltd. Treatment
AU2006304274B2 (en) 2005-10-13 2012-08-16 Celularity Inc. Production of oligodendrocytes from placenta-derived stem cells
EP1870107A1 (de) * 2006-06-23 2007-12-26 INSERM (Institut National de la Santé et de la Recherche Médicale) Verwendung eines PML Auslöser zur Behandlung von neurodegenerativen Krankheiten mit Polyglutamine Vermehrung
WO2008086449A2 (en) * 2007-01-09 2008-07-17 Oregon Health & Science University Synthetic osteopontin peptides and methods of use
US20100069254A1 (en) * 2008-09-16 2010-03-18 Laree Hiser Cell Culture Model for Demyelination/Remyelination
KR101449100B1 (ko) 2011-04-21 2014-10-13 가톨릭대학교 산학협력단 신경세포 데브리스 제거용 오스테오폰틴
GB2493540A (en) * 2011-08-10 2013-02-13 Follicum Ab Agents for stimulating hair growth in mammals
WO2014051398A1 (ko) * 2012-09-28 2014-04-03 한국생명공학연구원 아세카이니드 또는 이의 유도체를 포함하는 근력약화 관련 질환의 예방 또는 치료용 약학적 조성물
CA2957958C (en) * 2014-08-27 2023-10-17 Harvey Cantor Intracellular osteopontin regulates the lineage commitment of lymphoid subsets
US11058720B2 (en) 2016-05-20 2021-07-13 Cedars-Sinai Medical Center Methods of treating or preventing alzheimer's disease and associated conditions
CN109996810B (zh) * 2016-11-27 2023-08-22 特里同阿盖亚创新公司 从微藻中纯化重组骨桥蛋白的方法
AU2018262805B2 (en) 2017-05-04 2022-02-17 Follicum Ab Peptides for treatment of diabetes
CN111315394A (zh) * 2017-08-15 2020-06-19 儿童医疗中心有限公司 作为用于神经元病变的治疗剂的骨桥蛋白
KR20210050493A (ko) * 2018-05-25 2021-05-07 더 칠드런스 메디칼 센터 코포레이션 척수 손상의 치료 방법
TR201903865A2 (tr) * 2019-03-14 2020-09-21 Bogazici Ueniversitesi Amyotrofi̇k lateral skleroz tedavi̇si̇ i̇çi̇n i̇nterferon kullanimi
WO2021024265A1 (en) * 2019-08-08 2021-02-11 Ramot At Tel-Aviv University Ltd. Methods of treating non-infectious inflammatory disorders
CN111388654A (zh) * 2020-05-22 2020-07-10 南通大学 治疗脊髓损伤的药物、药物试剂盒及方法
WO2021246744A1 (ko) * 2020-06-02 2021-12-09 가톨릭대학교 산학협력단 오스테오폰틴 억제제를 유효성분으로 포함하는 퇴행성 신경계질환의 예방, 개선 또는 치료용 조성물
CN117720620B (zh) * 2023-12-13 2024-07-23 无锡市儿童医院 小分子多肽和其药物组合物、其制药用途

Family Cites Families (4)

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Publication number Priority date Publication date Assignee Title
EP1579871A1 (de) 1998-12-22 2005-09-28 Genentech, Inc. Antagonisten von vaskular-endothelialen Zellwachstumsfaktoren und ihre Anwendung
CA2370129A1 (en) * 1999-04-15 2000-10-26 Children's Medical Center Corporation Methods and compositions for modulating an immune response
AU3667100A (en) * 1999-04-23 2000-11-10 Sulzer Orthopedics Ltd Composition for enhancing functional recovery of a mammal from central and/or peripheral nervous system injury of traumatic or pathological origin
EP1221975B1 (de) 1999-10-04 2006-12-06 Nektar Therapeutics Al, Corporation Polymer-stabilisierte neuropeptide

Also Published As

Publication number Publication date
CN1533283A (zh) 2004-09-29
NZ528852A (en) 2005-12-23
CA2443964A1 (en) 2002-11-21
PL211763B1 (pl) 2012-06-29
CN1286524C (zh) 2006-11-29
EP1389130A2 (de) 2004-02-18
SK14232003A3 (sk) 2004-05-04
US20040235720A1 (en) 2004-11-25
JP5036761B2 (ja) 2012-09-26
EE200300559A (et) 2004-02-16
US20070225214A1 (en) 2007-09-27
UA85368C2 (ru) 2009-01-26
EA200301253A1 (ru) 2004-06-24
HK1067051A1 (en) 2005-04-01
US7217687B2 (en) 2007-05-15
BG108337A (bg) 2004-12-30
EA006655B1 (ru) 2006-02-24
US20080213234A1 (en) 2008-09-04
WO2002092122A2 (en) 2002-11-21
IL158867A0 (en) 2004-05-12
IL158867A (en) 2010-05-17
US20050176639A1 (en) 2005-08-11
HUP0400005A2 (hu) 2004-04-28
KR100947424B1 (ko) 2010-03-12
HRP20030840A2 (en) 2005-08-31
JP2009191082A (ja) 2009-08-27
WO2002092122A3 (en) 2003-03-06
AU2002312886B2 (en) 2007-10-25
NO20035025D0 (no) 2003-11-12
PL367065A1 (en) 2005-02-21
JP4417632B2 (ja) 2010-02-17
MXPA03010327A (es) 2004-02-17
JP2004536058A (ja) 2004-12-02
KR20040008176A (ko) 2004-01-28
US7297099B2 (en) 2007-11-20
EP1389130B1 (de) 2012-05-02
HUP0400005A3 (en) 2012-09-28
YU89503A (sh) 2006-05-25
BR0209812A (pt) 2004-06-01
CZ20033109A3 (en) 2004-06-16
CN1939538A (zh) 2007-04-04
ES2387082T3 (es) 2012-09-13
NO20035025L (no) 2003-11-12
ZA200307956B (en) 2004-10-13

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