ATE557040T1 - Rekombinante antikörper sowie zusammensetzungen und verfahren zu deren herstellung und verwendung - Google Patents

Rekombinante antikörper sowie zusammensetzungen und verfahren zu deren herstellung und verwendung

Info

Publication number
ATE557040T1
ATE557040T1 AT02794932T AT02794932T ATE557040T1 AT E557040 T1 ATE557040 T1 AT E557040T1 AT 02794932 T AT02794932 T AT 02794932T AT 02794932 T AT02794932 T AT 02794932T AT E557040 T1 ATE557040 T1 AT E557040T1
Authority
AT
Austria
Prior art keywords
recombinant antibodies
compositions
production
methods
antibodies
Prior art date
Application number
AT02794932T
Other languages
English (en)
Inventor
Douglas Hooper
Bernhard Dietzschold
Original Assignee
Univ Jefferson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Jefferson filed Critical Univ Jefferson
Application granted granted Critical
Publication of ATE557040T1 publication Critical patent/ATE557040T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT02794932T 2001-08-21 2002-08-21 Rekombinante antikörper sowie zusammensetzungen und verfahren zu deren herstellung und verwendung ATE557040T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31402301P 2001-08-21 2001-08-21
PCT/US2002/026584 WO2003016501A2 (en) 2001-08-21 2002-08-21 Recombinant antibodies, and compositions and methods for making and using the same

Publications (1)

Publication Number Publication Date
ATE557040T1 true ATE557040T1 (de) 2012-05-15

Family

ID=23218208

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02794932T ATE557040T1 (de) 2001-08-21 2002-08-21 Rekombinante antikörper sowie zusammensetzungen und verfahren zu deren herstellung und verwendung

Country Status (9)

Country Link
EP (1) EP1530579B1 (de)
CN (1) CN1636019B (de)
AT (1) ATE557040T1 (de)
AU (1) AU2002332600B2 (de)
CA (1) CA2457362C (de)
MX (1) MXPA04001609A (de)
NZ (1) NZ531291A (de)
RU (1) RU2292353C2 (de)
WO (1) WO2003016501A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040013672A1 (en) * 2000-05-16 2004-01-22 Thomas Jefferson University Recombinant antibodies, and compositions and methods for making and using the same
USRE47770E1 (en) 2002-07-18 2019-12-17 Merus N.V. Recombinant production of mixtures of antibodies
PT2314629E (pt) 2002-07-18 2014-01-22 Merus B V Produção recombinante de misturas de anticorpos
EP2395016A3 (de) 2003-05-30 2012-12-19 Merus B.V. Entwurf und Verwendung von gepaarten unterschiedlichen Regionen von spezifisch bindenden Molekülen
US20100069614A1 (en) 2008-06-27 2010-03-18 Merus B.V. Antibody producing non-human mammals
US20060134099A1 (en) * 2003-06-02 2006-06-22 Biotechnology Foundation, Inc. Production of rabies antibodies in plants
JP5912211B2 (ja) 2004-01-20 2016-04-27 メルス ビー．ヴィー． 結合タンパク質の混合物
NZ580607A (en) * 2004-05-27 2011-05-27 Crucell Holland Bv Binding molecules capable of neutralizing rabies virus and uses thereof
WO2007045465A1 (en) 2005-10-21 2007-04-26 F. Hoffmann-La Roche Ag Method for the recombinant expression of a polypeptide
CN101100663B (zh) * 2006-07-05 2011-08-24 华北制药集团新药研究开发有限责任公司 重组人抗狂犬病毒单克隆抗体的制备方法
AU2007328960B2 (en) 2006-12-05 2013-01-17 Crucell Holland B.V. Liquid anti-rabies antibody formulations
CN101337990B (zh) * 2008-06-25 2011-04-06 中国人民解放军军事医学科学院微生物流行病研究所 人源抗狂犬病毒中和性抗体及其制备方法与用途
CN101696242B (zh) * 2009-10-26 2011-12-28 中国人民解放军南京军区军事医学研究所 人源抗狂犬病毒中和抗体Fab及其制备方法和应用
DK2838917T3 (da) 2012-04-20 2019-08-26 Merus Nv Fremgangsmåder og midler til frembringelse af heterodimere ig-lignende molekyler
RU2682677C2 (ru) * 2017-09-07 2019-03-20 Федеральное бюджетное учреждение науки "Екатеринбургский научно-исследовательский институт вирусных инфекций" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН "ЕНИИВИ" Роспотребнадзора) Способ постэкспозиционной профилактики клещевого энцефалита

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2130187C1 (ru) * 1997-10-01 1999-05-10 Всероссийский научно-исследовательский институт ветеринарной вирусологии и микробиологии Способ определения антирабических вируснейтрализующих антител
IL152825A (en) * 2000-05-16 2009-07-20 Univ Jefferson Rabies virus-specific neutralizing human monoclonal antibodies and nucleic acids and related methods

Also Published As

Publication number Publication date
CN1636019A (zh) 2005-07-06
WO2003016501A2 (en) 2003-02-27
EP1530579A4 (de) 2006-02-08
NZ531291A (en) 2006-02-24
AU2002332600B2 (en) 2007-03-22
RU2292353C2 (ru) 2007-01-27
CA2457362A1 (en) 2003-02-27
WO2003016501A3 (en) 2005-03-24
CA2457362C (en) 2012-01-17
RU2004108115A (ru) 2005-09-27
MXPA04001609A (es) 2005-03-07
EP1530579B1 (de) 2012-05-09
HK1071898A1 (en) 2005-08-05
EP1530579A2 (de) 2005-05-18
CN1636019B (zh) 2010-06-16

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