ATE55921T1 - PROCESS FOR MAKING PARTICLES OF EQUAL DIMENSIONS FROM WATER-INSOLUBLE ORGANIC MATERIAL. - Google Patents

PROCESS FOR MAKING PARTICLES OF EQUAL DIMENSIONS FROM WATER-INSOLUBLE ORGANIC MATERIAL.

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Publication number
ATE55921T1
ATE55921T1 AT85201206T AT85201206T ATE55921T1 AT E55921 T1 ATE55921 T1 AT E55921T1 AT 85201206 T AT85201206 T AT 85201206T AT 85201206 T AT85201206 T AT 85201206T AT E55921 T1 ATE55921 T1 AT E55921T1
Authority
AT
Austria
Prior art keywords
particles
water
insoluble organic
organic material
solvent
Prior art date
Application number
AT85201206T
Other languages
German (de)
Inventor
Michael R Violante
Harry W Fischer
Original Assignee
Sterilization Techn Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterilization Techn Serv filed Critical Sterilization Techn Serv
Priority claimed from EP85201206A external-priority patent/EP0169618B2/en
Application granted granted Critical
Publication of ATE55921T1 publication Critical patent/ATE55921T1/en

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  • Physical Or Chemical Processes And Apparatus (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention relates to a method for preparing particles of uniform size from drugs or other water-insoluble organic compounds. Firstly, a suitable solid organic compound is dissolved in an organic solvent and the solution may be diluted with a non-solvent liquid. Next, an aqueous precipitant liquid is infused, precipitating non-aggregated particles with substantially uniform mean diameters. The particles are then separated out from the organic solvent. Depending on the organic compound and on the size of the particles which is desired, in accordance with the invention the parameters of temperature, ratio of non-solvent liquid to organic solvent, speed of infusion, speed of agitation and volume may vary.
AT85201206T 1984-05-21 1985-05-21 PROCESS FOR MAKING PARTICLES OF EQUAL DIMENSIONS FROM WATER-INSOLUBLE ORGANIC MATERIAL. ATE55921T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61272584A 1984-05-21 1984-05-21
EP85201206A EP0169618B2 (en) 1984-05-21 1985-05-21 Method for making uniformly sized particles from water-insoluble organic compounds

Publications (1)

Publication Number Publication Date
ATE55921T1 true ATE55921T1 (en) 1990-09-15

Family

ID=24454400

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85201206T ATE55921T1 (en) 1984-05-21 1985-05-21 PROCESS FOR MAKING PARTICLES OF EQUAL DIMENSIONS FROM WATER-INSOLUBLE ORGANIC MATERIAL.

Country Status (6)

Country Link
AT (1) ATE55921T1 (en)
DE (1) DE3579385D1 (en)
ES (1) ES8607007A1 (en)
IL (1) IL75250A (en)
NO (1) NO930571L (en)
NZ (1) NZ212151A (en)

Also Published As

Publication number Publication date
NO930571D0 (en) 1993-02-18
NO930571L (en) 1993-02-18
DE3579385D1 (en) 1990-10-04
IL75250A0 (en) 1985-09-29
IL75250A (en) 1988-08-31
ES543354A0 (en) 1986-06-01
NZ212151A (en) 1988-08-30
ES8607007A1 (en) 1986-06-01

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