ATE58475T1 - Waessrige loesung fuer die augen zur behandlung der trockenheit u/o der reizung von menschlichen oder tierischen augen. - Google Patents

Waessrige loesung fuer die augen zur behandlung der trockenheit u/o der reizung von menschlichen oder tierischen augen.

Info

Publication number: ATE58475T1
Authority: AT; Austria
Prior art keywords: human; preparation; treatment; chelating; propylmethylcellulose
Prior art date: 1986-09-04

Application number

AT87112701T

Other languages

English (en)

Inventor

Shambhu Dayal Varma

Original Assignee

Vision Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-09-04

Filing date

1987-09-01

Publication date

1990-12-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25417752&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE58475(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1987-09-01 Application filed by Vision Pharma Inc filed Critical Vision Pharma Inc

1990-12-15 Application granted granted Critical

1990-12-15 Publication of ATE58475T1 publication Critical patent/ATE58475T1/de

Links

230000007794 irritation Effects 0.000 title 1
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 3
FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 abstract 1
FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical group OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical group OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 abstract 1
229940123457 Free radical scavenger Drugs 0.000 abstract 1
229930195725 Mannitol Natural products 0.000 abstract 1
230000003139 buffering effect Effects 0.000 abstract 1
150000001768 cations Chemical class 0.000 abstract 1
239000002738 chelating agent Substances 0.000 abstract 1
150000001860 citric acid derivatives Chemical class 0.000 abstract 1
239000000470 constituent Substances 0.000 abstract 1
230000007760 free radical scavenging Effects 0.000 abstract 1
235000010355 mannitol Nutrition 0.000 abstract 1
239000000594 mannitol Substances 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1
150000001455 metallic ions Chemical class 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000002736 nonionic surfactant Substances 0.000 abstract 1
229940054534 ophthalmic solution Drugs 0.000 abstract 1
239000002997 ophthalmic solution Substances 0.000 abstract 1
239000002516 radical scavenger Substances 0.000 abstract 1
229960003471 retinol Drugs 0.000 abstract 1
235000020944 retinol Nutrition 0.000 abstract 1
239000011607 retinol Substances 0.000 abstract 1
239000000243 solution Substances 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
239000011782 vitamin Substances 0.000 abstract 1
229940088594 vitamin Drugs 0.000 abstract 1
229930003231 vitamin Natural products 0.000 abstract 1
235000013343 vitamin Nutrition 0.000 abstract 1
150000003722 vitamin derivatives Chemical class 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cosmetics (AREA)

AT87112701T 1986-09-04 1987-09-01 Waessrige loesung fuer die augen zur behandlung der trockenheit u/o der reizung von menschlichen oder tierischen augen. ATE58475T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/903,597 US5032392A (en)	1986-09-04	1986-09-04	Aqueous ophthalmic solutions for the treatment of dryness and/or irritation of human or animal eyes
EP87112701A EP0258865B2 (de)	1986-09-04	1987-09-01	Wässrige Lösung für die Augen zur Behandlung der Trockenheit u/o der Reizung von menschlichen oder tierischen Augen

Publications (1)

Publication Number	Publication Date
ATE58475T1 true ATE58475T1 (de)	1990-12-15

Family

ID=25417752

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT87112701T ATE58475T1 (de)	1986-09-04	1987-09-01	Waessrige loesung fuer die augen zur behandlung der trockenheit u/o der reizung von menschlichen oder tierischen augen.

Country Status (9)

Country	Link
US (1)	US5032392A (de)
EP (1)	EP0258865B2 (de)
JP (1)	JPH0751500B2 (de)
AT (1)	ATE58475T1 (de)
AU (1)	AU599695B2 (de)
CA (1)	CA1341393C (de)
DE (1)	DE3766322D1 (de)
GR (2)	GR3001098T3 (de)
IN (1)	IN165608B (de)

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US5360611A (en) *	1988-10-03	1994-11-01	Alcon Laboratories, Inc.	Pharmaceutical compositions and methods of treatment of the cornea following ultraviolet laser irradiation
EP0464727B1 (de) *	1990-06-29	1996-01-03	Santen Pharmaceutical Co., Ltd.	Verwendung einer Zusammensetzung zur Herstellung eines Medicamentes zur Entfernung der Reste von Linsenmaterialien
JP3256997B2 (ja) *	1990-08-30	2002-02-18	千寿製薬株式会社	安定な水性製剤
US5505953A (en)	1992-05-06	1996-04-09	Alcon Laboratories, Inc.	Use of borate-polyol complexes in ophthalmic compositions
ATE300936T1 (de) *	1992-05-06	2005-08-15	Alcon Lab Inc	Anwendung von boral-polyol-komplexen für ophthalmische arzneizusammensetzungen
US5366739A (en) *	1992-08-06	1994-11-22	Deo Corporation	Method of ophthalmic drug delivery
US5830508A (en)	1992-08-06	1998-11-03	Deo Corporation	Composition for treating dry eye
US5382599A (en) *	1993-10-13	1995-01-17	Allergan, Inc.	Method of inhibiting protozoan growth in eye care products using a polyvalent cation chelating agent
US5494817A (en) *	1993-12-06	1996-02-27	Allergan, Inc.	Sugar-based protease composition for use with constant-PH borate buffers
EP1163906A3 (de) *	1994-03-15	2003-05-21	Senju Pharmaceutical Co., Ltd.	Verfahren zur Stabilisierung von Pranoprofen und stabile flüssige Zubereitung von Pranoprofen
CN1160346A (zh) *	1994-09-14	1997-09-24	大正制药株式会社	用于修复角膜损伤的滴眼液
US6113894A (en) *	1995-01-23	2000-09-05	Smith; S. Gregory	Ophthalmic compositions and process of using
US5861148A (en) *	1995-01-23	1999-01-19	Smith; Stewart Gregory	Ophthalmic compositions and process of using
DE19511322C2 (de) *	1995-03-28	1999-09-02	Mann Gerhard Chem Pharm Fab	Sterile Augengele mit einem Gehalt an mittelkettigen Triglyceriden und Verfahren zu deren Herstellung
US5783407A (en) *	1996-04-05	1998-07-21	Beckman Instruments, Inc.	Method of measuring bilirubin
DE19614823A1 (de) *	1996-04-15	1997-10-16	Mann Gerhard Chem Pharm Fab	Ophthalmische Zusammensetzung mit verlängerter Verweilzeit am Auge
EP0938896A1 (de)	1998-01-15	1999-09-01	Novartis AG	In Autoklaven behandelbare pharmazeutische Zusammensetzungen mit Komplexbildner
US6726922B1 (en)	1999-06-28	2004-04-27	Minu, L.L.C.	Process and composition for temporarily suppressing pain
JP2001158734A (ja) *	1999-12-02	2001-06-12	Lion Corp	眼科用組成物及びソフトコンタクトレンズに対する吸着抑制方法
JP4713706B2 (ja) *	2000-03-14	2011-06-29	テルモ株式会社	脂溶性ビタミン可溶化液入り容器
PT1304991E (pt) *	2000-07-12	2014-12-09	Rogue Valley Natural Springs Inc	Método e kit para a hidratação da superfície do olho
US7524511B1 (en) *	2000-07-12	2009-04-28	Rogue Valley Natural Springs, Inc.	Method and kit for moisturizing the surface of the eye
EP1207208A3 (de) *	2000-11-15	2003-12-10	Becton Dickinson and Company	Methode zur Erhaltung von Zellen und Nukleinsäurezielmolekülen
US6506412B2 (en) *	2000-11-29	2003-01-14	Sciencebased Health	Treatment of dry eye syndrome
WO2002049613A2 (en) *	2000-12-19	2002-06-27	Bausch & Lomb Incorporated	Method for enhancing integrity of epithelium using retinoic acid
SE520715C2 (sv) *	2001-12-03	2003-08-12	Akzo Nobel Nv	Förfarande för framställning av metylcellulosaetrar
US20060172972A1 (en) *	2002-12-20	2006-08-03	Chakshu Research Inc	Formulation and method for administration of ophthalmologically active agents
US20060166879A1 (en) *	2002-12-20	2006-07-27	Chakshu Research Inc	Treatment of conditions associated with the presence of macromolecular aggregates, particularly ophthalmic disorders
US20050065091A1 (en) *	2003-09-18	2005-03-24	Gholam Peyman	Stabilized ocular solutions
JP2008519054A (ja)	2004-11-04	2008-06-05	シリオンセラピューティクス，インコーポレイテッド	レチノール−レチノール結合タンパク質（ｒｂｐ）−トランスチレチン（ｔｔｒ）複合体の形成のモジュレーター
WO2007098040A1 (en) *	2006-02-17	2007-08-30	Novartis Ag	Method for sterilization of hydrogel contact lenses
WO2008137496A1 (en) *	2007-05-04	2008-11-13	Bausch & Lomb Incorporated	Compositions for reducing, ameliorating, treating, or preventing condition of dry eye and methods of making and using same
WO2011072141A1 (en)	2009-12-11	2011-06-16	Neuron Systems, Inc.	Compositions and methods for the treatment of macular degeneration
US8865685B2 (en)	2011-06-30	2014-10-21	Johnson & Johnson Vision Care, Inc.	Esters for treatment of ocular inflammatory conditions
JP6179204B2 (ja) *	2012-06-08	2017-08-16	ライオン株式会社	粘膜用組成物及びその製造方法
CN117045653A (zh)	2013-01-23	2023-11-14	奥尔德拉医疗公司	与毒性醛相关的疾病和治疗
WO2014121027A1 (en)	2013-02-01	2014-08-07	Oculars Pharma, Llc	Aqueous ophthalmic solutions of phentolamine and medical uses thereof
EP2950800B1 (de)	2013-02-01	2020-09-09	Ocuphire Pharma, Inc.	Verfahren und zusammensetzungen für die tägliche ophthalmische verabreichung von phentolamin zur verbesserung der sehfähigkeit
US10550085B2 (en)	2015-08-21	2020-02-04	Aldeyra Therapeutics, Inc.	Deuterated compounds and uses thereof
ES2669446B1 (es) *	2016-11-24	2019-03-13	Saiz Manuel Munoz	Producto oftálmico
JP2021504349A (ja) *	2017-11-24	2021-02-15	ジー−トゥリー・ビーエヌティ・カンパニー・リミテッドＧ−ＴｒｅｅｂｎｔＣｏ．，Ｌｔｄ．	チモシンβ４またはその誘導体を有効成分として含む杯細胞増殖またはムチン分泌を促進するための組成物
AU2019319740A1 (en)	2018-08-06	2021-03-25	Aldeyra Therapeutics, Inc.	Polymorphic compounds and uses thereof
EP3866790A4 (de)	2018-10-15	2022-08-03	Ocuphire Pharma, Inc.	Verfahren und zusammensetzungen zur behandlung von glaukom und verwandten leiden
JP7670945B2 (ja)	2018-10-26	2025-05-01	オーパス・ジェネティクス・インコーポレイテッド	老眼、散瞳、および他の眼障害の治療のための方法および組成物
US11786518B2 (en)	2019-03-26	2023-10-17	Aldeyra Therapeutics, Inc.	Ophthalmic formulations and uses thereof
WO2020223717A1 (en)	2019-05-02	2020-11-05	Aldeyra Therapeutics, Inc.	Process for preparation of aldehyde scavenger and intermediates
JP2022530967A (ja)	2019-05-02	2022-07-05	アルデイラセラピューティクス，インコーポレイテッド	多形化合物およびその使用
WO2021231792A1 (en)	2020-05-13	2021-11-18	Aldeyra Therapeutics, Inc.	Pharmaceutical formulations and uses thereof
CN115368310B (zh)	2021-05-18	2025-06-27	奥库菲尔医药公司	合成甲磺酸酚妥拉明的方法

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US3384545A (en) *	1965-03-09	1968-05-21	Hoffmann La Roche	Injectable aqueous emulsions of fat soluble vitamins
GB1431841A (en) *	1973-01-15	1976-04-14	Evans S C	Ophthalmic-nutritional preparations
US4409205A (en) *	1979-03-05	1983-10-11	Cooper Laboratories, Inc.	Ophthalmic solution
US4219545A (en) *	1979-03-23	1980-08-26	Collins Calvin E	Treatment of infectious keratoconjunctivitis in animals
IE54026B1 (en) *	1981-10-09	1989-05-24	Baylor College Medicine	Use of methotrexate and/or retinoic acid for the manufacture of compositions for use in preventing proliferation of remnant lens epithelial cells after extracapsular extraction
US4515794A (en) *	1981-10-09	1985-05-07	Baylor College Of Medicine	Mitotic inhibitors preventing posterior lens capsule opacification
US4421748A (en) *	1982-07-13	1983-12-20	Trager Seymour F	Artificial tear aid

1986
- 1986-09-04 US US06/903,597 patent/US5032392A/en not_active Expired - Lifetime
1987
- 1987-08-28 CA CA000545654A patent/CA1341393C/en not_active Expired - Fee Related
- 1987-09-01 AT AT87112701T patent/ATE58475T1/de active
- 1987-09-01 DE DE8787112701T patent/DE3766322D1/de not_active Expired - Fee Related
- 1987-09-01 EP EP87112701A patent/EP0258865B2/de not_active Expired - Lifetime
- 1987-09-04 IN IN644/MAS/87A patent/IN165608B/en unknown
- 1987-09-04 JP JP62221795A patent/JPH0751500B2/ja not_active Expired - Fee Related
- 1987-09-04 AU AU77978/87A patent/AU599695B2/en not_active Ceased
1990
- 1990-11-23 GR GR90400840T patent/GR3001098T3/el unknown
1995
- 1995-02-01 GR GR950400201T patent/GR3014937T3/el unknown

Also Published As

Publication number	Publication date
US5032392A (en)	1991-07-16
AU7797887A (en)	1988-03-10
EP0258865B2 (de)	1995-01-04
DE3766322D1 (de)	1991-01-03
EP0258865A3 (en)	1989-03-08
JPH0751500B2 (ja)	1995-06-05
IN165608B (de)	1989-11-25
AU599695B2 (en)	1990-07-26
EP0258865B1 (de)	1990-11-22
GR3001098T3 (en)	1992-04-17
GR3014937T3 (en)	1995-05-31
JPS63208516A (ja)	1988-08-30
EP0258865A2 (de)	1988-03-09
CA1341393C (en)	2002-10-15

Publication	Publication Date	Title
ATE58475T1 (de)	1990-12-15	Waessrige loesung fuer die augen zur behandlung der trockenheit u/o der reizung von menschlichen oder tierischen augen.
JP2988658B2 (ja)	1999-12-13	非水性皮膚軟化剤入りヨードフォア製剤
DK159789D0 (da)	1989-04-03	Medikeret hudplejepraeparat, dets fremstilling og anvendelse
ATE113834T1 (de)	1994-11-15	Zusammensetzung zur behandlung der schizophrenie.
KR870010862A (ko)	1987-12-18	비내투여용 수성 스테로이드 제제
NO975962L (no)	1998-02-18	Legemiddelpreparat som omfatter albumin som aktiv bestanddel
KR100260061B1 (en)	2000-07-01	Vitamin e drop
ATE179888T1 (de)	1999-05-15	Ophthalmische zubereitung zur behandlung oder prävention von trockenem auge und krankheiten, die dadurch verursacht werden, enthaltend 12- sulfodehydroabietsäure
ATE51343T1 (de)	1990-04-15	Abwaschbare topische zubereitung zur therapie der psoriasis.
EP0354554A2 (de)	1990-02-14	Reizvermeidende und desensibilisierende Zusammensetzungen und Verfahren zu deren Anwendung
US3694547A (en)	1972-09-26	Anti-dandruff hair preparation
DE3784628D1 (de)	1993-04-15	Dermale behandlung von wurmerkrankungen der katze mit praziquantel.
ATE33760T1 (de)	1988-05-15	Mittel zur oertlichen anwendung am koerper.
US4692262A (en)	1987-09-08	Skin cleanser capable of softening and removing smegma
ATE168004T1 (de)	1998-07-15	Juckreizstillendes mittel
DK0514009T3 (da)	1995-08-07	Hornhindebehandlingsmiddel
JPS6442424A (en)	1989-02-14	Ophthalmic solution
JPS568324A (en)	1981-01-28	Infectious disease remedy for external and ophthalmologic application
ATE187077T1 (de)	1999-12-15	Wässrige zubereitung mit verzögerter wirkstofffreigabe
Kawai et al.	1979	The Influence of surfactants upon the skin IV The influence of Sodium Lauryl Sulfate upon the skin
JPS5573607A (en)	1980-06-03	Novel method to remove fundamentally cause of extremely uncurable smell of armpit by only administering certain antibiotic or applying it affected part
GB1184200A (en)	1970-03-11	Improvements in or relating to the Treatment of Animal Tissue
JPS5636410A (en)	1981-04-09	Ointment for treating athlete's foot
CA2243824A1 (en)	1997-07-31	Therapeutic agent for keratoconjunctiva diseases
ES512751A0 (es)	1985-09-16	"procedimiento para la preparacion de un colirio antiseptico para afecciones oculares".