ATE61485T1 - Verfahren und hilfsmittel zur vorbehandlung von seren zum bestimmen von dizoxin und dabei erhaltenes dizoxinkonzentrat. - Google Patents

Verfahren und hilfsmittel zur vorbehandlung von seren zum bestimmen von dizoxin und dabei erhaltenes dizoxinkonzentrat.

Info

Publication number: ATE61485T1
Authority: AT; Austria
Prior art keywords: dizoxin; digoxin; sera; determination; treatment
Prior art date: 1984-06-15

Application number

AT85304259T

Other languages

English (en)

Inventor

Pyare Khanna

Anne Jennifer Stone

Roberta Dorothea Ernst

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-06-15

Filing date

1985-06-14

Publication date

1991-03-15

1985-06-14 Application filed by Syntex Inc filed Critical Syntex Inc

1991-03-15 Application granted granted Critical

1991-03-15 Publication of ATE61485T1 publication Critical patent/ATE61485T1/de

Links

239000012141 concentrate Substances 0.000 title abstract 3
238000000034 method Methods 0.000 title 1
238000002203 pretreatment Methods 0.000 title 1
LTMHDMANZUZIPE-AMTYYWEZSA-N Digoxin Natural products O([C@H]1[C@H](C)O[C@H](O[C@@H]2C[C@@H]3[C@@](C)([C@@H]4[C@H]([C@]5(O)[C@](C)([C@H](O)C4)[C@H](C4=CC(=O)OC4)CC5)CC3)CC2)C[C@@H]1O)[C@H]1O[C@H](C)[C@@H](O[C@H]2O[C@@H](C)[C@H](O)[C@@H](O)C2)[C@@H](O)C1 LTMHDMANZUZIPE-AMTYYWEZSA-N 0.000 abstract 4
LTMHDMANZUZIPE-PUGKRICDSA-N digoxin Chemical compound C1[C@H](O)[C@H](O)[C@@H](C)O[C@H]1O[C@@H]1[C@@H](C)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@@H]3C[C@@H]4[C@]([C@@H]5[C@H]([C@]6(CC[C@@H]([C@@]6(C)[C@H](O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)C[C@@H]2O)C)C[C@@H]1O LTMHDMANZUZIPE-PUGKRICDSA-N 0.000 abstract 4
229960005156 digoxin Drugs 0.000 abstract 4
LTMHDMANZUZIPE-UHFFFAOYSA-N digoxine Natural products C1C(O)C(O)C(C)OC1OC1C(C)OC(OC2C(OC(OC3CC4C(C5C(C6(CCC(C6(C)C(O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)CC2O)C)CC1O LTMHDMANZUZIPE-UHFFFAOYSA-N 0.000 abstract 4
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
210000002966 serum Anatomy 0.000 abstract 2
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
238000003556 assay Methods 0.000 abstract 1
238000013375 chromatographic separation Methods 0.000 abstract 1
239000000741 silica gel Substances 0.000 abstract 1
229910002027 silica gel Inorganic materials 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9453—Cardioregulators, e.g. antihypotensives, antiarrhythmics
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
- Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Hematology (AREA)
Chemical & Material Sciences (AREA)
Urology & Nephrology (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Food Science & Technology (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Cell Biology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Investigating Or Analysing Biological Materials (AREA)

AT85304259T 1984-06-15 1985-06-14 Verfahren und hilfsmittel zur vorbehandlung von seren zum bestimmen von dizoxin und dabei erhaltenes dizoxinkonzentrat. ATE61485T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/621,301 US4654311A (en)	1984-06-15	1984-06-15	Serum pretreatment for digoxin assay
EP85304259A EP0168968B1 (de)	1984-06-15	1985-06-14	Verfahren und Hilfsmittel zur Vorbehandlung von Seren zum Bestimmen von Dizoxin und dabei erhaltenes Dizoxinkonzentrat

Publications (1)

Publication Number	Publication Date
ATE61485T1 true ATE61485T1 (de)	1991-03-15

Family

ID=24489604

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT85304259T ATE61485T1 (de)	1984-06-15	1985-06-14	Verfahren und hilfsmittel zur vorbehandlung von seren zum bestimmen von dizoxin und dabei erhaltenes dizoxinkonzentrat.

Country Status (6)

Country	Link
US (1)	US4654311A (de)
EP (1)	EP0168968B1 (de)
JP (1)	JPH0723892B2 (de)
AT (1)	ATE61485T1 (de)
CA (1)	CA1254511A (de)
DE (1)	DE3581970D1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4652529A (en) *	1984-10-02	1987-03-24	Syntex (U.S.A.) Inc.	Serum pretreatment for tricyclic antidepressant drug assays
US4734378A (en) *	1985-06-26	1988-03-29	Abbott Laboratories	Precipitation of interfering proteins in fluorescence polarization immunoassay for digoxin
DE3738467A1 (de) *	1986-11-12	1988-06-01	Hitachi Ltd	Verfahren und vorrichtung zur fluessigkeitschromatographie
DE3643760A1 (de) *	1986-12-20	1988-06-23	Boehringer Mannheim Gmbh	Verfahren zur anreicherung und/oder isolierung von herzglykosiden unter verwendung unpolarer adsorberharze
US4798804A (en) *	1987-02-05	1989-01-17	Syntex (U.S.A.) Inc.	Serum pretreatment in digoxin immunoassay
FI890341A7 (fi) *	1988-01-26	1989-07-27	Hoechst Ag	Menetelmä polyhalogenoitujen, tasomaisten, polysyklisten, aromaattisten hiilivetyjen immunodiagnostiseksi määrittämiseksi
US5395521A (en) *	1991-05-31	1995-03-07	Board Of Regents, The University Of Texas System	Automated column equilibration, column loading, column washing and column elution
EP0995803A3 (de) *	1998-10-20	2001-11-07	Matsushita Electric Industrial Co., Ltd.	Kit zum Probebehandeln und Verfahren zum Probebehandeln für Analyse mit einem Biosensor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2137397B1 (de) *	1971-05-12	1973-05-25	Degussa
US3817837A (en) *	1971-05-14	1974-06-18	Syva Corp	Enzyme amplification assay
DE2410033C2 (de) *	1974-03-02	1975-09-11	Merck Patent Gmbh, 6100 Darmstadt	Isolierung von in lipophilen Lösungsmitteln löslichen Inhaltstoffen wäßriger Lösungen
US3981982A (en) *	1974-09-11	1976-09-21	Abbott Laboratories	Radioimmunoassay for determining the digoxin content of a sample
JPS5344466A (en) *	1976-10-05	1978-04-21	Toyota Motor Co Ltd	Hemming method and device
US4469797A (en) *	1982-09-23	1984-09-04	Miles Laboratories, Inc.	Digoxigenin immunogens, antibodies, labeled conjugates, and related derivatives

1984
- 1984-06-15 US US06/621,301 patent/US4654311A/en not_active Expired - Lifetime
1985
- 1985-06-14 AT AT85304259T patent/ATE61485T1/de active
- 1985-06-14 JP JP60130669A patent/JPH0723892B2/ja not_active Expired - Lifetime
- 1985-06-14 DE DE8585304259T patent/DE3581970D1/de not_active Expired - Lifetime
- 1985-06-14 CA CA000483985A patent/CA1254511A/en not_active Expired
- 1985-06-14 EP EP85304259A patent/EP0168968B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US4654311A (en)	1987-03-31
DE3581970D1 (de)	1991-04-11
EP0168968B1 (de)	1991-03-06
EP0168968A1 (de)	1986-01-22
JPH0723892B2 (ja)	1995-03-15
CA1254511A (en)	1989-05-23
JPS6111662A (ja)	1986-01-20

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