ATE62254T1 - Multispezifische immunogene proteine. - Google Patents

Multispezifische immunogene proteine.

Info

Publication number: ATE62254T1
Authority: AT; Austria
Prior art keywords: protein; hapten; molecular weight; aggregating; self
Prior art date: 1984-08-22

Application number

AT85305989T

Other languages

English (en)

Inventor

Eric A James

Robert T Garvin

Joel R Haynes

Original Assignee

Connaught Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-08-22

Filing date

1985-08-22

Publication date

1991-04-15

1985-08-22 Application filed by Connaught Lab filed Critical Connaught Lab

1991-04-15 Application granted granted Critical

1991-04-15 Publication of ATE62254T1 publication Critical patent/ATE62254T1/de

Links

108090000623 proteins and genes Proteins 0.000 title abstract 5
102000004169 proteins and genes Human genes 0.000 title abstract 5
230000002163 immunogen Effects 0.000 title abstract 2
108010067390 Viral Proteins Proteins 0.000 abstract 2
230000001717 pathogenic effect Effects 0.000 abstract 2
102000014914 Carrier Proteins Human genes 0.000 abstract 1
108010078791 Carrier Proteins Proteins 0.000 abstract 1
108020004511 Recombinant DNA Proteins 0.000 abstract 1
238000004220 aggregation Methods 0.000 abstract 1
230000002776 aggregation Effects 0.000 abstract 1
239000000427 antigen Substances 0.000 abstract 1
102000036639 antigens Human genes 0.000 abstract 1
108091007433 antigens Proteins 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
210000000987 immune system Anatomy 0.000 abstract 1
230000036039 immunity Effects 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000002245 particle Substances 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
229960005486 vaccine Drugs 0.000 abstract 1
230000003612 virological effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/00022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Immunology (AREA)
General Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Physics & Mathematics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Plant Pathology (AREA)
Microbiology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Virology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

AT85305989T 1984-08-22 1985-08-22 Multispezifische immunogene proteine. ATE62254T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB848421282A GB8421282D0 (en)	1984-08-22	1984-08-22	Multispecific antigenic proteins
EP85305989A EP0174759B1 (de)	1984-08-22	1985-08-22	Multispezifische immunogene Proteine

Publications (1)

Publication Number	Publication Date
ATE62254T1 true ATE62254T1 (de)	1991-04-15

Family

ID=10565652

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT85305989T ATE62254T1 (de)	1984-08-22	1985-08-22	Multispezifische immunogene proteine.

Country Status (7)

Country	Link
US (1)	US5972659A (de)
EP (1)	EP0174759B1 (de)
JP (1)	JP2528815B2 (de)
AT (1)	ATE62254T1 (de)
CA (1)	CA1340776C (de)
DE (1)	DE3582380D1 (de)
GB (1)	GB8421282D0 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4722840A (en) *	1984-09-12	1988-02-02	Chiron Corporation	Hybrid particle immunogens
EP0175261B1 (de) *	1984-09-12	1991-12-11	Chiron Corporation	Hybridpartikel-Immunogene
EP0264150B1 (de) *	1986-10-13	1993-01-07	Solvay	Mikroorganismen, die fremdproteinenthaltende Pili tragen, isolierte Pili, Verfahren zur Ausscheidung von Proteinen in Verwendung dieser Pili und deren Nutzen
AP56A (en) *	1987-01-30	1989-09-26	Smithkline Biologicals S A	Hepatitis B virus surface antigens and hybrid antigehs containing them.
CA1341074C (en) *	1987-06-22	2000-08-08	Hans A. Thoma	Hbv surface antigen particles, prepared by recombinant dna processes, composed of different epitopes, selected from the pre-s and s-peptides as a new vaccine
US7033835B1 (en)	1988-02-26	2006-04-25	Large Scale Biology Corporation	Production of peptides in plants as viral coat protein fusions
US6846968B1 (en)	1988-02-26	2005-01-25	Large Scale Biology Corporation	Production of lysosomal enzymes in plants by transient expression
US6660500B2 (en)	1988-02-26	2003-12-09	Large Scale Biology Corporation	Production of peptides in plants as viral coat protein fusions
US5977438A (en) *	1988-02-26	1999-11-02	Biosource Technologies, Inc.	Production of peptides in plants as viral coat protein fusions
GB8903313D0 (en) *	1989-02-14	1989-04-05	Wellcome Found	Conjugates
EP0491077A1 (de) *	1990-12-19	1992-06-24	Medeva Holdings B.V.	Zusammensetzung verwendbar als therapeutisches Mittel gegen chronische virale Leberkrankheiten
GB9108386D0 (en) *	1991-04-19	1991-06-05	Agricultural Genetics Co	Modified plant viruses as vectors
WO1994016084A1 (en) *	1993-01-16	1994-07-21	British Bio-Technology Limited	Hybrid particle-forming protein comprising a particle-inducing segment and a plurality of antigens
JP2688879B2 (ja) *	1994-02-08	1997-12-10	騏一小林	切断器
GB9414118D0 (en) *	1994-07-13	1994-08-31	Axis Genetics Ltd	Modified plant viruses as vectors of heterologous peptides
CA2202761A1 (en)	1994-10-18	1996-04-25	Sean Nicholas Chapman	Method of producing a chimeric protein
US6042832A (en) *	1996-08-28	2000-03-28	Thomas Jefferson University	Polypeptides fused with alfalfa mosaic virus or ilarvirus capsid proteins
US20060165606A1 (en)	1997-09-29	2006-07-27	Nektar Therapeutics	Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6759243B2 (en)	1998-01-20	2004-07-06	Board Of Trustees Of The University Of Illinois	High affinity TCR proteins and methods
US8404217B2 (en)	2000-05-10	2013-03-26	Novartis Ag	Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
WO2001085136A2 (en)	2000-05-10	2001-11-15	Alliance Pharmaceutical Corporation	Phospholipid-based powders for drug delivery
US7871598B1 (en)	2000-05-10	2011-01-18	Novartis Ag	Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
CU23002A1 (es)	2000-12-01	2004-11-18	Ct Ingenieria Genetica Biotech	Método de obtención de agregados antigénicos y su uso en formulaciones
US8206950B2 (en) *	2003-06-09	2012-06-26	Animal Technology Institute Taiwan	Fusion antigen used as vaccine and method of making them
WO2021226026A2 (en) *	2020-05-04	2021-11-11	Hexamer Therapeutics, Inc.	Vaccines against viral pathogens

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0006553A1 (de) *	1978-07-03	1980-01-09	International Business Machines Corporation	Verfahren und Vorrichtung zum Betrieb einer Heizquelle in einem Kopiergerät
IL61904A (en) *	1981-01-13	1985-07-31	Yeda Res & Dev	Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same
CA1192510A (en) *	1981-05-27	1985-08-27	Lawrence E. Pelcher	Rna plant virus vector or portion thereof, a method of construction thereof, and a method of producing a gene derived product therefrom
US4496538A (en) *	1982-07-06	1985-01-29	Connaught Laboratories, Inc.	Haemophilus influenzae b polysaccharide-diphtheria toxoid conjugate vaccine
US4694072A (en) *	1982-11-30	1987-09-15	Institut Pasteur	Peptides comprising an immunogenic site of poliovirus and DNAS containing nucleotide sequences coding for these peptides
US4722840A (en) *	1984-09-12	1988-02-02	Chiron Corporation	Hybrid particle immunogens
US5316931A (en) *	1988-02-26	1994-05-31	Biosource Genetics Corp.	Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes

1984
- 1984-08-22 GB GB848421282A patent/GB8421282D0/en active Pending
1985
- 1985-08-20 CA CA000489080A patent/CA1340776C/en not_active Expired - Fee Related
- 1985-08-22 EP EP85305989A patent/EP0174759B1/de not_active Expired - Lifetime
- 1985-08-22 JP JP60183149A patent/JP2528815B2/ja not_active Expired - Lifetime
- 1985-08-22 AT AT85305989T patent/ATE62254T1/de not_active IP Right Cessation
- 1985-08-22 DE DE8585305989T patent/DE3582380D1/de not_active Expired - Lifetime
1995
- 1995-06-07 US US08/472,178 patent/US5972659A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0174759A1 (de)	1986-03-19
US5972659A (en)	1999-10-26
DE3582380D1 (de)	1991-05-08
EP0174759B1 (de)	1991-04-03
JP2528815B2 (ja)	1996-08-28
CA1340776C (en)	1999-10-05
GB8421282D0 (en)	1984-09-26
JPS61143327A (ja)	1986-07-01

Legal Events

Date	Code	Title	Description
1992-01-15	UEP	Publication of translation of european patent specification
2005-11-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
ATE62254T1 (de)	1991-04-15	Multispezifische immunogene proteine.
EP0154902A3 (en)	1987-12-16	Pre-s gene coded peptide hepatitis b immunogens, vaccines, diagnostics, and synthetic lipid vesicle carriers
CA2143823A1 (en)	1994-03-17	Retro-, inverso - and retro-inverso synthetic peptide analogues
EP0243913A3 (de)	1988-08-10	Pre-S Gen codierte peptidische Hepatitis B Immunogene, Impfstoffe, Diagnosemittel und synthetische Lipid Transportvesikel
DE10299017I1 (de)	2002-08-29	Hepatitis-B-Oberflaechenantigen enthaltendes Peptid
NO872988D0 (no)	1987-07-17	Pattedyr-interleukin-4.
ATE90384T1 (de)	1993-06-15	Rekombinante virusproteine begleitet von lymphadenopathischem syndrom und/oder ''acquired immune deficiency syndrome'' (aids).
Jemmerson et al.	1986	Mapping antigenic sites on proteins: Implications for the design of synthetic vaccines.
ES2109217T3 (es)	1998-01-16	Determinante peptidico asociado con la inmunidad.
DE3585578D1 (de)	1992-04-16	Hepatitisoberflaechenantigenpartikelvakzin.
EP0193585A4 (de)	1988-04-18	Kreuzreaktive und schützende epitope von circumsporozoit-proteinen.
EP0293827A3 (de)	1991-03-20	Probe für Leishmaniosis
DE68917138D1 (de)	1994-09-01	Toleranzinduktion gegenüber einem fremdantigen.
AU532186B2 (en)	1983-09-22	Herpes virus vaccine
AU7145087A (en)	1988-10-13	Tumor-associated antigens (mol wt 160,000-170,000; 44,000-46,000; 29,000-35,000)
IL108419A (en)	1997-07-13	Proteinaceous extract derived from eimeria maxima gametocytes and vaccines against eimeria maxima containing the same