ATE63306T1 - Indolderivate. - Google Patents

Indolderivate.

Info

Publication number: ATE63306T1
Authority: AT; Austria
Prior art keywords: alkyl; alkenyl; indole derivatives; alkylene; co2r
Prior art date: 1986-01-28

Application number

AT87300741T

Other languages

English (en)

Inventor

David Edmund Bays

Alexander William Oxford

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-28

Filing date

1987-01-28

Publication date

1991-05-15

1987-01-28 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1991-05-15 Application granted granted Critical

1991-05-15 Publication of ATE63306T1 publication Critical patent/ATE63306T1/de

Links

125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 4
125000003342 alkenyl group Chemical group 0.000 abstract 3
229940054051 antipsychotic indole derivative Drugs 0.000 abstract 3
150000002475 indoles Chemical class 0.000 abstract 3
125000002947 alkylene group Chemical group 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
125000006656 (C2-C4) alkenyl group Chemical group 0.000 abstract 1
125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
125000006705 (C5-C7) cycloalkyl group Chemical group 0.000 abstract 1
125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
208000019695 Migraine disease Diseases 0.000 abstract 1
-1 ar(C1-4)-alkylene Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
239000000969 carrier Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
150000004677 hydrates Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
206010027599 migraine Diseases 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1
239000005526 vasoconstrictor agent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT87300741T 1986-01-28 1987-01-28 Indolderivate. ATE63306T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB868601959A GB8601959D0 (en)	1986-01-28	1986-01-28	Indole derivatives
EP87300741A EP0242939B1 (de)	1986-01-28	1987-01-28	Indolderivate

Publications (1)

Publication Number	Publication Date
ATE63306T1 true ATE63306T1 (de)	1991-05-15

Family

ID=10592018

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT87300741T ATE63306T1 (de)	1986-01-28	1987-01-28	Indolderivate.

Country Status (6)

Country	Link
EP (1)	EP0242939B1 (de)
JP (1)	JPS62281857A (de)
AT (1)	ATE63306T1 (de)
DE (1)	DE3769833D1 (de)
ES (1)	ES2054660T3 (de)
GB (1)	GB8601959D0 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5225431A (en) *	1987-10-23	1993-07-06	Burroughs Wellcome Co.	Therapeutic substituted indole compounds and compositions thereof
GB8903036D0 (en) *	1989-02-10	1989-03-30	Glaxo Group Ltd	Chemical compounds
CA2043709C (en) *	1990-06-29	2002-01-22	David W. Smith	Antimigraine alkoxypyrimidine derivatives
GB9103770D0 (en) *	1991-02-22	1991-04-10	Glaxo Group Ltd	Chemical compounds
GB9211277D0 (en)	1992-05-28	1992-07-15	Glaxo Group Inc	Pharmaceutical compositions
GB9515305D0 (en) *	1995-07-26	1995-09-20	Wellcome Found	Therapeutic heterocyclic compounds
US7189753B1 (en)	1997-11-06	2007-03-13	Cady Roger K	Preemptive prophylaxis of migraine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GR79215B (de) *	1982-06-07	1984-10-22	Glaxo Group Ltd
GB8332437D0 (en) *	1983-12-06	1984-01-11	Glaxo Group Ltd	Chemical compounds
GB8332435D0 (en) *	1983-12-06	1984-01-11	Glaxo Group Ltd	Chemical compounds
GB8332434D0 (en) *	1983-12-06	1984-01-11	Glaxo Group Ltd	Production of chemical compounds
GB2162522B (en) *	1984-08-01	1988-02-24	Glaxo Group Ltd	An indole derivative

1986
- 1986-01-28 GB GB868601959A patent/GB8601959D0/en active Pending
1987
- 1987-01-28 EP EP87300741A patent/EP0242939B1/de not_active Expired - Lifetime
- 1987-01-28 JP JP62018145A patent/JPS62281857A/ja active Pending
- 1987-01-28 DE DE8787300741T patent/DE3769833D1/de not_active Expired - Fee Related
- 1987-01-28 AT AT87300741T patent/ATE63306T1/de not_active IP Right Cessation
- 1987-01-28 ES ES87300741T patent/ES2054660T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE3769833D1 (de)	1991-06-13
GB8601959D0 (en)	1986-03-05
EP0242939B1 (de)	1991-05-08
EP0242939A1 (de)	1987-10-28
JPS62281857A (ja)	1987-12-07
ES2054660T3 (es)	1994-08-16

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Legal Events

Date	Code	Title	Description
1991-12-15	UEP	Publication of translation of european patent specification
1994-10-15	REN	Ceased due to non-payment of the annual fee