ATE63306T1 - Indolderivate. - Google Patents
Indolderivate.Info
- Publication number
- ATE63306T1 ATE63306T1 AT87300741T AT87300741T ATE63306T1 AT E63306 T1 ATE63306 T1 AT E63306T1 AT 87300741 T AT87300741 T AT 87300741T AT 87300741 T AT87300741 T AT 87300741T AT E63306 T1 ATE63306 T1 AT E63306T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- alkenyl
- indole derivatives
- alkylene
- co2r
- Prior art date
Links
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 4
- 125000003342 alkenyl group Chemical group 0.000 abstract 3
- 229940054051 antipsychotic indole derivative Drugs 0.000 abstract 3
- 150000002475 indoles Chemical class 0.000 abstract 3
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 abstract 1
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
- 125000006705 (C5-C7) cycloalkyl group Chemical group 0.000 abstract 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- -1 ar(C1-4)-alkylene Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 239000005526 vasoconstrictor agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868601959A GB8601959D0 (en) | 1986-01-28 | 1986-01-28 | Indole derivatives |
| EP87300741A EP0242939B1 (de) | 1986-01-28 | 1987-01-28 | Indolderivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE63306T1 true ATE63306T1 (de) | 1991-05-15 |
Family
ID=10592018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87300741T ATE63306T1 (de) | 1986-01-28 | 1987-01-28 | Indolderivate. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0242939B1 (de) |
| JP (1) | JPS62281857A (de) |
| AT (1) | ATE63306T1 (de) |
| DE (1) | DE3769833D1 (de) |
| ES (1) | ES2054660T3 (de) |
| GB (1) | GB8601959D0 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225431A (en) * | 1987-10-23 | 1993-07-06 | Burroughs Wellcome Co. | Therapeutic substituted indole compounds and compositions thereof |
| GB8903036D0 (en) * | 1989-02-10 | 1989-03-30 | Glaxo Group Ltd | Chemical compounds |
| CA2043709C (en) * | 1990-06-29 | 2002-01-22 | David W. Smith | Antimigraine alkoxypyrimidine derivatives |
| GB9103770D0 (en) * | 1991-02-22 | 1991-04-10 | Glaxo Group Ltd | Chemical compounds |
| GB9211277D0 (en) | 1992-05-28 | 1992-07-15 | Glaxo Group Inc | Pharmaceutical compositions |
| GB9515305D0 (en) * | 1995-07-26 | 1995-09-20 | Wellcome Found | Therapeutic heterocyclic compounds |
| US7189753B1 (en) | 1997-11-06 | 2007-03-13 | Cady Roger K | Preemptive prophylaxis of migraine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR79215B (de) * | 1982-06-07 | 1984-10-22 | Glaxo Group Ltd | |
| GB8332435D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Chemical compounds |
| GB8332437D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Chemical compounds |
| GB8332434D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Production of chemical compounds |
| GB2162522B (en) * | 1984-08-01 | 1988-02-24 | Glaxo Group Ltd | An indole derivative |
-
1986
- 1986-01-28 GB GB868601959A patent/GB8601959D0/en active Pending
-
1987
- 1987-01-28 DE DE8787300741T patent/DE3769833D1/de not_active Expired - Fee Related
- 1987-01-28 JP JP62018145A patent/JPS62281857A/ja active Pending
- 1987-01-28 AT AT87300741T patent/ATE63306T1/de not_active IP Right Cessation
- 1987-01-28 EP EP87300741A patent/EP0242939B1/de not_active Expired - Lifetime
- 1987-01-28 ES ES87300741T patent/ES2054660T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GB8601959D0 (en) | 1986-03-05 |
| EP0242939B1 (de) | 1991-05-08 |
| DE3769833D1 (de) | 1991-06-13 |
| ES2054660T3 (es) | 1994-08-16 |
| EP0242939A1 (de) | 1987-10-28 |
| JPS62281857A (ja) | 1987-12-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |