ATE64304T1 - Verfahren zur verleihung von immuntoleranz gegen ein spezifisches antigen. - Google Patents
Verfahren zur verleihung von immuntoleranz gegen ein spezifisches antigen.Info
- Publication number
- ATE64304T1 ATE64304T1 AT86302781T AT86302781T ATE64304T1 AT E64304 T1 ATE64304 T1 AT E64304T1 AT 86302781 T AT86302781 T AT 86302781T AT 86302781 T AT86302781 T AT 86302781T AT E64304 T1 ATE64304 T1 AT E64304T1
- Authority
- AT
- Austria
- Prior art keywords
- specific antigen
- antigen
- immuntolerance
- confering
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Transplantation (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/724,063 US4681760A (en) | 1985-04-17 | 1985-04-17 | Method of conferring immunotolerance to a specific antigen |
| EP86302781A EP0200412B1 (de) | 1985-04-17 | 1986-04-15 | Verfahren zur Verleihung von Immuntoleranz gegen ein spezifisches Antigen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE64304T1 true ATE64304T1 (de) | 1991-06-15 |
Family
ID=24908815
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86302781T ATE64304T1 (de) | 1985-04-17 | 1986-04-15 | Verfahren zur verleihung von immuntoleranz gegen ein spezifisches antigen. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4681760A (de) |
| EP (1) | EP0200412B1 (de) |
| JP (1) | JP2530316B2 (de) |
| AT (1) | ATE64304T1 (de) |
| CA (1) | CA1266232A (de) |
| DE (1) | DE3679708D1 (de) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8608068D0 (en) * | 1986-04-02 | 1986-05-08 | Cobbold S P | Monoclonal antibodies |
| US4842862A (en) * | 1986-07-03 | 1989-06-27 | International Minerals & Chemical Corp. | Immunostimulating agents |
| US5034223A (en) * | 1986-10-09 | 1991-07-23 | Neorx Corporation | Methods for improved targeting of antibody, antibody fragments, hormones and other targeting agents, and conjugates thereof |
| USRE38008E1 (en) | 1986-10-09 | 2003-02-25 | Neorx Corporation | Methods for improved targeting of antibody, antibody fragments, hormones and other targeting agents, and conjugates thereof |
| US5723128A (en) * | 1987-01-30 | 1998-03-03 | The Board Of Trustees Of The Leland Stanford Junior University | Cytotoxic T-cell lymphocyte ("CTL") activity regulation by class I MHC peptides |
| US5888512A (en) * | 1987-01-30 | 1999-03-30 | Board Of Trustees Of The Leland Stanford Junior University | Lymphocyte activity regulation by HLA peptides |
| US7011834B1 (en) | 1987-01-30 | 2006-03-14 | The Board Of Trustees Of Leland Stanford Junior University | Immunomodulating dimers |
| US4898730A (en) * | 1987-03-13 | 1990-02-06 | The University Of British Columbia | Method to stimulate the immune response to specific antigens |
| US4861589A (en) * | 1987-03-23 | 1989-08-29 | Trustees Of Boston University | Method for therapeutically treating abnormal cells expressing a major histocompatibility complex class II antigen using cytolytic inducer T4 cells |
| CA1336818C (en) * | 1987-04-16 | 1995-08-29 | International Institute Of Cellular And Molecular Pathology | Treatment of allergy and composition thereof |
| US5571500A (en) * | 1987-06-24 | 1996-11-05 | Autoimmune, Inc. | Treatment of autoimmune diseases through administration by inhalation of autoantigens |
| US5571499A (en) * | 1987-06-24 | 1996-11-05 | Autoimmune, Inc. | Treatment of autoimmune diseases by aerosol administration of autoantigens |
| US5641474A (en) * | 1987-06-24 | 1997-06-24 | Autoimmune, Inc. | Prevention of autoimmune diseases by aerosol administration of autoantigens |
| US5645820A (en) * | 1987-06-24 | 1997-07-08 | Autoimmune, Inc. | Treatment of autoimmune diseases by aerosol administration of autoantigens |
| US5449760A (en) * | 1987-12-31 | 1995-09-12 | Tanox Biosystems, Inc. | Monoclonal antibodies that bind to soluble IGE but do not bind IGE on IGE expressing B lymphocytes or basophils |
| US5422258A (en) * | 1987-12-31 | 1995-06-06 | Tanox Biosystems, Inc. | Methods for producing high affinity anti-human IgE-monoclonal antibodies which binds to IgE on IgEabearing B cells but not basophils |
| WO1989006967A1 (en) * | 1988-02-03 | 1989-08-10 | Xoma Corporation | Immunosupression with anti-pan t-cell immunotoxin compositions |
| US5152980A (en) * | 1988-05-19 | 1992-10-06 | The Beth Israel Hospital Association | Induction of tolerance to a foreign antigen IL-2 receptor-binding substances |
| ATE109004T1 (de) * | 1988-05-19 | 1994-08-15 | Beth Israel Hospital | Toleranzinduktion gegenüber einem fremdantigen. |
| ATE130197T1 (de) * | 1988-06-14 | 1995-12-15 | Cell Med Inc | Heterofunktionelle zellular immunologische reagenzien, impfstoffe daraus und verwendungsverfahren. |
| US5260422A (en) * | 1988-06-23 | 1993-11-09 | Anergen, Inc. | MHC conjugates useful in ameliorating autoimmunity |
| US5194425A (en) * | 1988-06-23 | 1993-03-16 | Anergen, Inc. | Mhc-mediated toxic conjugates useful in ameliorating autoimmunity |
| US5690933A (en) * | 1989-05-31 | 1997-11-25 | Glaxo Wellcome Inc. | Monoclonal antibodies for inducing tolerance |
| US7037496B2 (en) | 1989-12-27 | 2006-05-02 | Centocor, Inc. | Chimeric immunoglobulin for CD4 receptors |
| CA2015515C (en) * | 1990-01-03 | 1999-12-07 | Jean-Marie Saint-Remy | Pharmaceutical compositions containing antigen-antibody complexes and uses therefor |
| CA2085586A1 (en) * | 1990-06-22 | 1991-12-23 | Timothy J. Gorzynski | Ascites production of monoclonal antibodies using an immunosuppressive anti-cd4-related antibody |
| GB9020282D0 (en) | 1990-09-17 | 1990-10-31 | Gorman Scott D | Altered antibodies and their preparation |
| US6764681B2 (en) * | 1991-10-07 | 2004-07-20 | Biogen, Inc. | Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction |
| JPH07507441A (ja) * | 1991-11-01 | 1995-08-24 | ジヨスリン・ダイアビーテイス・センター | 1型真性糖尿病に関連する抗原 |
| JPH07508503A (ja) * | 1992-02-27 | 1995-09-21 | ザ・ボード・オブ・トラステイーズ・オブ・ザ・リランド・スタンフオード・ジユニア・ユニバーシテイ | 自己免疫性糖尿病のための初期抗原(early antigen) |
| US6696061B1 (en) | 1992-08-11 | 2004-02-24 | President And Fellows Of Harvard College | Immunomodulatory peptides |
| CA2142007C (en) | 1992-08-11 | 2007-10-30 | Robert Glen Urban | Immunomodulatory peptides |
| WO1994004557A1 (en) * | 1992-08-11 | 1994-03-03 | President And Fellows Of Harvard College | Immunomodulatory peptides |
| US5759546A (en) | 1994-02-04 | 1998-06-02 | Weinberg; Andrew D. | Treatment of CD4 T-cell mediated conditions |
| JPH08332344A (ja) * | 1995-06-09 | 1996-12-17 | Honda Motor Co Ltd | 内燃機関の排気浄化装置 |
| ES2210514T3 (es) * | 1996-04-10 | 2004-07-01 | Sangstat Medical Corporation | Conjugados citomoduladores de miembros de pares de union especificos. |
| US6312700B1 (en) | 1998-02-24 | 2001-11-06 | Andrew D. Weinberg | Method for enhancing an antigen specific immune response with OX-40L |
| US6617171B2 (en) * | 1998-02-27 | 2003-09-09 | The General Hospital Corporation | Methods for diagnosing and treating autoimmune disease |
| WO2000012113A2 (en) * | 1998-08-31 | 2000-03-09 | Biogen, Inc. | Method of modulating memory effector t-cells using a cd2-binding agent, and compositions |
| US6599710B1 (en) | 1999-03-10 | 2003-07-29 | The General Hospital Corporation | Treatment of autoimmune disease |
| CZ304942B6 (cs) * | 2000-03-31 | 2015-02-04 | Purdue Research Foundation | Léčivo pro zvyšování specifické eliminace populace tumorových buněk a farmaceutický prostředek obsahující konjugát fosfát-FITC nebo fosfát-dinitrofenyl |
| US7858095B2 (en) * | 2001-07-24 | 2010-12-28 | Astellas Us Llc | Method for treating or preventing sclerotic disorders using CD-2 binding agents |
| ES2338305T3 (es) * | 2001-09-28 | 2010-05-06 | Purdue Research Foundation | Metodo de tratamiento que utiliza conjugados ligando-inmunogeno. |
| US7582313B2 (en) * | 2002-06-27 | 2009-09-01 | The General Hospital Corporation | Methods of organ regeneration using Hox 11-expressing pluripotent cells |
| US7628988B2 (en) | 2002-06-27 | 2009-12-08 | The General Hospital Corporation | Methods and compositions for treating type 1 diabetes |
| WO2004045376A2 (en) * | 2002-11-15 | 2004-06-03 | The General Hospital Corporation | Screening methods to identify treatments for autoimmune disease |
| CN1953766A (zh) * | 2004-02-06 | 2007-04-25 | 安斯泰来美国有限公司 | 治疗皮肤病的方法 |
| MXPA06012744A (es) * | 2004-05-04 | 2007-02-19 | Genaissance Pharmaceutical Inc | Marcadores de haplotipo y metodos para utilizarlos en la determinacion de la respuesta al tratamiento. |
| WO2005115436A1 (en) * | 2004-05-07 | 2005-12-08 | Astellas Us Llc | Soluble lfa-3 polypeptide for treating viral disorders |
| US20080102054A1 (en) * | 2005-01-18 | 2008-05-01 | Faustman Denise L | Compositions Containing Agm Cells And Methods Of Use Thereof |
| EP2366106A2 (de) | 2008-11-21 | 2011-09-21 | Carla Perego | Verfahren und zusammensetzungen zur diagnose und behandlung von diabetes |
| HRP20211353T1 (hr) | 2013-02-07 | 2021-11-26 | The General Hospital Corporation | Postupci za ekspanziju ili depleciju regulacijskih t-stanica |
| CN111239415B (zh) | 2013-10-17 | 2024-03-26 | 综合医院公司 | 鉴定响应于用于自身免疫性疾病的治疗的受试者的方法以及用于治疗该疾病的组合物 |
| US10906982B2 (en) | 2015-05-15 | 2021-02-02 | The General Hospital Corporation | Antagonistic anti-tumor necrosis factor receptor 2 antibodies |
| EP3340999A4 (de) | 2015-08-28 | 2019-06-12 | The General Hospital Corporation | Agonistische anti-tumor-nekrosefaktorrezeptor-2-antikörper |
| US11266730B2 (en) | 2015-09-29 | 2022-03-08 | The General Hospital Corporation | Methods of treating and diagnosing disease using biomarkers for BCG therapy |
| CA3023930C (en) | 2016-05-13 | 2025-09-23 | The General Hospital Corporation | TUMOR-ANTAGONISTIC ANTIBODIES OF THE NECROSIS FACTOR RECEPTOR SUPERFAMILY |
| JP7652690B2 (ja) | 2018-11-15 | 2025-03-27 | ザ ジェネラル ホスピタル コーポレイション | アゴニスト性腫瘍壊死因子受容体スーパーファミリーポリペプチド |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4275000A (en) * | 1977-08-22 | 1981-06-23 | National Research Development Corporation | Peptide macromolecular complexes |
| DE2860875D1 (en) * | 1977-09-28 | 1981-10-15 | Nat Res Dev | Immunological preparations incorporating mhc antigens and their production |
| US4366246A (en) * | 1977-11-08 | 1982-12-28 | Genentech, Inc. | Method for microbial polypeptide expression |
| DE3105150A1 (de) * | 1981-02-12 | 1982-08-19 | Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG, 6380 Bad Homburg | Herstellung von anti-t-lymphozyten-globulin. |
| US4489710A (en) * | 1981-06-23 | 1984-12-25 | Xoma Corporation | Composition and method for transplantation therapy |
| US4443427A (en) * | 1982-06-21 | 1984-04-17 | Sidney Farber Cancer Institute, Inc. | Monoclonal antibody |
| US4520226A (en) * | 1982-07-19 | 1985-05-28 | The United States Of America As Represented By The Department Of Health And Human Services | Treatment of graft versus host disease using a mixture of T-lymphocyte specific monoclonal antibody: ricin conjugates |
| US4511502A (en) * | 1982-12-22 | 1985-04-16 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4511503A (en) * | 1982-12-22 | 1985-04-16 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4550086A (en) * | 1983-02-16 | 1985-10-29 | Dana-Farber Cancer Institute, Inc. | Monoclonal antibodies that recognize human T cells |
| DE3483996D1 (de) * | 1983-09-15 | 1991-02-28 | Univ Leland Stanford Junior | Allotransplantat mit verminderter immunogenitaet und verfahren und reagenz fuer seine herstellung. |
| US4695459A (en) * | 1984-12-26 | 1987-09-22 | The Board Of Trustees Of Leland Stanford Junior University | Method of treating autoimmune diseases that are mediated by Leu3/CD4 phenotype T cells |
-
1985
- 1985-04-17 US US06/724,063 patent/US4681760A/en not_active Expired - Lifetime
-
1986
- 1986-04-15 EP EP86302781A patent/EP0200412B1/de not_active Expired - Lifetime
- 1986-04-15 AT AT86302781T patent/ATE64304T1/de not_active IP Right Cessation
- 1986-04-15 DE DE8686302781T patent/DE3679708D1/de not_active Expired - Lifetime
- 1986-04-16 CA CA000506846A patent/CA1266232A/en not_active Expired - Lifetime
- 1986-04-17 JP JP61089192A patent/JP2530316B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US4681760A (en) | 1987-07-21 |
| EP0200412A3 (en) | 1988-03-30 |
| CA1266232A (en) | 1990-02-27 |
| EP0200412A2 (de) | 1986-11-05 |
| DE3679708D1 (de) | 1991-07-18 |
| JP2530316B2 (ja) | 1996-09-04 |
| EP0200412B1 (de) | 1991-06-12 |
| JPS6236A (ja) | 1987-01-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |