ATE66247T1 - Wiederhergestellter basalmembrankomplex mit biologischer aktivitaet. - Google Patents

Wiederhergestellter basalmembrankomplex mit biologischer aktivitaet.

Info

Publication number
ATE66247T1
ATE66247T1 AT86111635T AT86111635T ATE66247T1 AT E66247 T1 ATE66247 T1 AT E66247T1 AT 86111635 T AT86111635 T AT 86111635T AT 86111635 T AT86111635 T AT 86111635T AT E66247 T1 ATE66247 T1 AT E66247T1
Authority
AT
Austria
Prior art keywords
cells
nidogen
entactin
biologically active
composition
Prior art date
Application number
AT86111635T
Other languages
English (en)
Inventor
Hynda Karen Kleinman
George Reilly Martin
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Application granted granted Critical
Publication of ATE66247T1 publication Critical patent/ATE66247T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • G01N33/5017—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity for testing neoplastic activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/80—Undefined extracts from animals
    • C12N2500/84—Undefined extracts from animals from mammals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT86111635T 1985-08-30 1986-08-22 Wiederhergestellter basalmembrankomplex mit biologischer aktivitaet. ATE66247T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77140985A 1985-08-30 1985-08-30
US06/867,027 US4829000A (en) 1985-08-30 1986-05-27 Reconstituted basement membrane complex with biological activity
EP86111635A EP0218065B1 (de) 1985-08-30 1986-08-22 Wiederhergestellter Basalmembrankomplex mit biologischer Aktivität

Publications (1)

Publication Number Publication Date
ATE66247T1 true ATE66247T1 (de) 1991-08-15

Family

ID=27118460

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86111635T ATE66247T1 (de) 1985-08-30 1986-08-22 Wiederhergestellter basalmembrankomplex mit biologischer aktivitaet.

Country Status (6)

Country Link
US (1) US4829000A (de)
EP (1) EP0218065B1 (de)
JP (1) JPH0740932B2 (de)
AT (1) ATE66247T1 (de)
CA (1) CA1291432C (de)
DE (1) DE3680851D1 (de)

Families Citing this family (175)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5037656A (en) * 1986-12-04 1991-08-06 Millipore Corporation Porous membrane having hydrophilic and cell growth promotions surface and process
US5512657A (en) * 1988-12-12 1996-04-30 Bainbridge Sciences, Inc. Detection of complexes which include basement membrane components as diagnostic of cancer and other diseases
US5541076A (en) * 1988-12-12 1996-07-30 Bard Diagnostic Sciences, Inc. Methods for determining the invasiveness of a bladder tumor
EP0493533A4 (en) * 1989-10-27 1992-10-28 Case Western Reserve University Inhibition of cell growth by keratan sulfate, chondroitin sulfate, dermatan sulfate and other glycans
US5869266A (en) * 1990-03-06 1999-02-09 The United States Of America As Represented By The Department Of Health And Human Services Human olfactory neuron cultures to diagnose Alzheimer's disease
WO1991015245A1 (en) * 1990-03-30 1991-10-17 THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE Method and composition for growing tumors from few cells
US6133236A (en) * 1991-03-26 2000-10-17 Oregon Health Sciences University Products and methods for improving keratinocyte adhesion to the dermis
US5770562A (en) * 1991-03-26 1998-06-23 Oregon Health Sciences University Products and methods for improving keratinocyte adhesion to the dermis
JPH07504398A (ja) * 1991-03-26 1995-05-18 オレゴン州 真皮に対する表皮ケラチン細胞の接着を改善する生成物および方法
US5705178A (en) * 1991-05-31 1998-01-06 Gliatech, Inc. Methods and compositions based on inhibition of cell invasion and fibrosis by anionic polymers
US5605938A (en) * 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
US5354666A (en) * 1991-08-01 1994-10-11 Thomas Jefferson University Mammalian cell line expressing basement membrane proteins
US5547997A (en) * 1991-10-01 1996-08-20 Chemisches Laboratorium Dr. Kurt Richter Gmbh Plant-derived cosmetic composition and method of treatment of skin
US5175103A (en) * 1991-10-21 1992-12-29 Trustees Of University Of Pennsylvania Preparation of pure cultures of post-mitotic human neurons
US5508188A (en) * 1994-01-21 1996-04-16 The Regents Of The University Of California Method of growing cells in a mammal
DK0755258T3 (da) * 1994-04-13 2002-05-13 Res Corp Technologies Inc Fremgangsmåde til behandling af sygdom ved at anvende Sertoli-celler og allo-transplantater eller xeno-transplantater
US5741701A (en) * 1994-04-25 1998-04-21 Becton, Dickinson And Company Cell culture substrates and methods of use
US5834029A (en) * 1994-07-20 1998-11-10 Cytotherapeutics, Inc. Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment
US5935849A (en) * 1994-07-20 1999-08-10 Cytotherapeutics, Inc. Methods and compositions of growth control for cells encapsulated within bioartificial organs
US5795790A (en) 1994-07-20 1998-08-18 Cytotherapeutics, Inc. Method for controlling proliferation and differentiation of cells encapsulated within bioartificial organs
JPH10505750A (ja) * 1994-09-16 1998-06-09 ザ スクリップス リサーチ インスティテュート 粘着および軸索の成長を刺激するサイトタクチン誘導体並びにその製造および使用方法
US6485723B1 (en) * 1995-02-10 2002-11-26 Purdue Research Foundation Enhanced submucosal tissue graft constructs
US5695998A (en) * 1995-02-10 1997-12-09 Purdue Research Foundation Submucosa as a growth substrate for islet cells
US5830460A (en) 1995-03-13 1998-11-03 University Of South Florida Sertoli cells as transplantation facilitator for cell transplantation
US6495364B2 (en) * 1995-05-23 2002-12-17 Neurotech, S.A. Mx-1 conditionally immortalized cells
SK22499A3 (en) * 1996-08-23 1999-10-08 Cook Biotech Inc Graft prosthesis, materials and methods
US6696270B2 (en) * 1996-12-10 2004-02-24 Purdue Research Foundation Gastric submucosal tissue as a novel diagnostic tool
JP4046358B2 (ja) 1996-12-10 2008-02-13 パーデュー・リサーチ・ファウンデーション 粘膜下組織抽出物
AU732726B2 (en) * 1996-12-10 2001-04-26 Purdue Research Foundation Biomaterial derived from vertebrate liver tissue
US6152142A (en) 1997-02-28 2000-11-28 Tseng; Scheffer C. G. Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries
US6074874A (en) 1997-08-29 2000-06-13 University Of Pittsburgh Epithelial cell cultures for in vitro testing
AU2090799A (en) 1997-12-23 1999-07-12 Purdue Research Foundation Biomaterial derived from follicle basement membranes
WO1999043786A2 (en) 1998-02-27 1999-09-02 Purdue Research Foundation Submucosa gel compositions
US6667176B1 (en) * 2000-01-11 2003-12-23 Geron Corporation cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
US7410798B2 (en) * 2001-01-10 2008-08-12 Geron Corporation Culture system for rapid expansion of human embryonic stem cells
US7399751B2 (en) * 1999-11-04 2008-07-15 Sertoli Technologies, Inc. Production of a biological factor and creation of an immunologically privileged environment using genetically altered Sertoli cells
US6479072B1 (en) 1999-02-11 2002-11-12 The General Hospital Corporation Microfabricated membranes and matrices
US6815203B1 (en) * 1999-06-23 2004-11-09 Joslin Diabetes Center, Inc. Methods of making pancreatic islet cells
DE10003521A1 (de) * 2000-01-27 2001-08-09 Medigene Ag Vorrichtung zum Herstellen eines dreidimensionalen Matrixkörpers, Multi-Well-Platte, Lösung zum Kultivieren von Säugerkardiomyocyten, Verfahren zum Kultivieren einer Zellkultur, Vorrichtung für die Messung isometrischer Kraftparameter von Zellkulturen sowie Verfahren zum meßbaren Verfolgen von Kontraktionen eines in eine Trägersubstanz eingelagerten Zellgewebes
DE10010113B4 (de) * 2000-03-03 2009-05-07 Wolfgang Dr. Schatton Natives Schwammkollagen, Verfahren zu seiner Isolierung und seine Verwendung, sowie natives nanopartikuläres Schwammkollagen, Verfahren zu seiner Herstellung und seine Verwendung
AU8843701A (en) 2000-09-09 2002-03-22 Univ New York State Res Found Method and compositions for isolating metastatic cancer cells, and use in measuring metastatic potential of a cancer thereof
US6740501B2 (en) * 2000-09-27 2004-05-25 Becton, Dickinson And Company Coated membrane for assessing the invasive capacity of a cell
DK1349918T3 (da) * 2000-12-06 2014-11-10 Anthrogenesis Corp Fremgangsmåde til indsamling af stamceller fra moderkagen
EP2316919B1 (de) 2001-02-14 2015-10-07 Anthrogenesis Corporation Post-partum Säugetier-Plazenta, deren Verwendung und daraus gewonnene Stammzellen
CA2388723C (en) * 2001-06-06 2012-10-23 Becton, Dickinson & Company Method of providing a substrate with a ready-to-use, uniformly distributed extracellular matrix
US6706520B2 (en) 2001-06-13 2004-03-16 Kehan Han Assessment of invasive potential of tumor cells
JP4426285B2 (ja) * 2001-06-28 2010-03-03 クック・バイオテック・インコーポレーテッド 腎被膜コラーゲンを含有する移植片プロテーゼ用具
US20050244843A1 (en) * 2001-11-16 2005-11-03 Wen-Tien Chen Blood test prototypes and methods for the detection of circulating tumor and endothelial cells
WO2003059061A1 (en) * 2002-01-11 2003-07-24 Purdue Research Foundation Biomaterial derived from vertebrate liver tissue
AU2003226201A1 (en) * 2002-04-02 2003-10-20 William Marsh Rice University Redifferentiated cells for repairing cartilage defects
EP1503652A4 (de) * 2002-05-02 2006-02-08 Purdue Research Foundation Durch vaskularisierung verstärkte prothesenkonstrukte
CN1665527A (zh) * 2002-05-02 2005-09-07 普渡研究基金会 血管化增强的移植构造物
WO2003092381A1 (en) * 2002-05-02 2003-11-13 Purdue Research Foundation Vascularization enhanced graft constructs
JP2004075661A (ja) * 2002-06-18 2004-03-11 Shiseido Co Ltd 表皮基底膜ケアを特徴とする皮膚外用剤、皮膚基底膜構造形成促進剤および人工皮膚の製造方法
HUE025872T2 (en) * 2002-06-18 2016-05-30 Eisai R&D Man Co Ltd Primary, cultured adipocytes for gene therapy
AU2003298775B2 (en) 2002-11-26 2008-07-17 Anthrogenesis Corporation Cytotherapeutics, cytotherapeutic units and methods for treatments using them
US20040191226A1 (en) * 2002-12-04 2004-09-30 Badylak Stephen F. Method for repair of body wall
US20040187877A1 (en) * 2002-12-04 2004-09-30 Badylak Stephen F. Method for repair of liver tissue
AU2003294541A1 (en) * 2002-12-24 2004-07-22 An-Go-Gen Inc. Encapsulated cell for therapy
WO2004076631A2 (en) * 2003-02-21 2004-09-10 The Uab Research Foundation Biologically active native biomatrix composition
US20040176855A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Decellularized liver for repair of tissue and treatment of organ deficiency
US20040175366A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Scaffold for cell growth and differentiation
WO2005014619A2 (en) 2003-03-28 2005-02-17 Thomas Jefferson University Heparin-binding peptides and uses thereof
CA2530490A1 (en) 2003-06-25 2005-01-13 Stephen F. Badylak Conditioned matrix compositions for tissue restoration
CA2531022C (en) * 2003-07-03 2014-09-09 Jannette Dufour Compositions containing sertoli cells and myoid cells and use thereof in cellular transplants
US7608455B2 (en) * 2003-08-20 2009-10-27 Becton, Dickinson And Company Modified reconstituted basement membrane composition for assay system
US20050079611A1 (en) * 2003-08-20 2005-04-14 Min Wu Modified reconstituted basement membrane composition for assay system
GB0321337D0 (en) * 2003-09-11 2003-10-15 Massone Mobile Advertising Sys Method and system for distributing advertisements
US20050208627A1 (en) * 2003-09-18 2005-09-22 Bowdish Katherine S Elicitation of antibodies to self peptides in mice by immunization with dendritic cells
US20070054378A1 (en) * 2003-09-18 2007-03-08 Alexion Pharmaceuticals, Inc. Elicitation of antibodies to self peptides in mice by immunization with dendritic cells
WO2005042048A2 (en) 2003-10-22 2005-05-12 Encelle, Inc. Bioactive hydrogel compositions for regenerating connective tissue
CN1922304A (zh) * 2003-10-31 2007-02-28 维特克公司 用于检测循环肿瘤和内皮细胞的血液测试样机和方法
EP1689321B1 (de) 2003-11-07 2017-01-04 The University of Connecticut Künstliche gewebesysteme und ihre verwendungen
CN1961283A (zh) * 2004-03-26 2007-05-09 细胞基因公司 建立干细胞库的系统和方法
CA2565203A1 (en) * 2004-03-31 2005-10-20 Cook Incorporated Ecm-based graft material
US8377484B1 (en) 2004-05-06 2013-02-19 Maria V. Tsiper Tumor encapsulation for prevention and treatment of metastatic cancer disease
EP1765981A4 (de) * 2004-06-11 2007-09-12 Victorian Tissue Engineering C Gewebematerial und aus muskel gewonnene matrix
DK1879606T3 (da) 2005-04-25 2013-09-23 Massachusetts Inst Technology Selvorganiserende peptider til fremme af hæmostase
US9162005B2 (en) 2005-04-25 2015-10-20 Arch Biosurgery, Inc. Compositions for prevention of adhesions and other barrier applications
WO2006121923A2 (en) * 2005-05-06 2006-11-16 Orion Biosolutions, Inc. Cns cells in vitro
US8048446B2 (en) * 2005-05-10 2011-11-01 Drexel University Electrospun blends of natural and synthetic polymer fibers as tissue engineering scaffolds
WO2006138718A2 (en) 2005-06-17 2006-12-28 Drexel University Three-dimensional scaffolds for tissue engineering made by processing complex extracts of natural extracellular matrices
US8187639B2 (en) 2005-09-27 2012-05-29 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
CA2999420A1 (en) 2005-09-27 2007-04-05 Tissuetech, Inc. Amniotic membrane preparations and purified compositions and methods of use
DK1957633T3 (en) 2005-10-13 2014-03-17 Anthrogenesis Corp Immunomodulation USING PLACE SPEECH STEM CELLS
US20070190165A1 (en) * 2005-10-21 2007-08-16 Brey Eric M Tissue-specific basement membrane gels
PT2471904T (pt) * 2005-12-29 2019-02-25 Celularity Inc População de células estaminais placentárias
CN101389754A (zh) 2005-12-29 2009-03-18 人类起源公司 胎盘干细胞和第二来源干细胞的联合培养
ES2673947T3 (es) 2006-04-25 2018-06-26 Massachusetts Institute Of Technology Composiciones y métodos para afectar al movimiento de contaminantes, líquidos corporales u otras entidades y/o afectar a otras condiciones fisiológicas
AU2008216748A1 (en) * 2007-02-12 2008-08-21 Anthrogenesis Corporation Hepatocytes and chondrocytes from adherent placental stem cells; and CD34+, CD45- placental stem cell-enriched cell populations
EP3763376A1 (de) 2007-02-12 2021-01-13 Celularity, Inc. Behandlung von infektionskrankheiten mithilfe von plazenta-stammzellen
US9415084B2 (en) 2007-03-14 2016-08-16 Arch Biosurgery, Inc. Treatment of leaky or damaged tight junctions and enhancing extracellular matrix
TWM322542U (en) * 2007-05-23 2007-11-21 Universal Scient Ind Co Ltd Testing machine
DE102007026639A1 (de) 2007-06-06 2008-12-11 Stefan-Andreas Ulrich Industrielle Fertigung tierischer Lederhautsubstitute für die Lederproduktion aus etablierten Epithelzelllinien und/oder primären Epithelzellkulturen, wie vorzugsweise Fibroplasten, Melanozyten, Keratiozyten sowie deren Verfahren und Vorrichtungen
US9200253B1 (en) 2007-08-06 2015-12-01 Anthrogenesis Corporation Method of producing erythrocytes
WO2009029578A2 (en) * 2007-08-27 2009-03-05 Shell Oil Company A carrier, a process for preparing the carrier, an olefin epoxidation catalyst, a process for preparing the catalyst, and a process for the production of an olefin oxide, a 1,2-diol, a 1,2-diol ether, or an alkanolamine
WO2009042768A1 (en) * 2007-09-25 2009-04-02 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Triggerably dissolvable hollow fibers for controlled delivery
NZ599825A (en) 2007-09-28 2014-10-31 Anthrogenesis Corp Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
US20090130756A1 (en) 2007-11-20 2009-05-21 Pioneer Surgical Orthobiologics,Inc. Cryopreservation of cells using cross-linked bioactive hydrogel matrix particles
WO2009073178A1 (en) 2007-12-03 2009-06-11 Sanbio, Inc. Extracellular matrix from pluripotent cells
EP2254608B1 (de) 2008-02-07 2016-05-04 Shahar Cohen Kompartimenten-extrakt-zusammensetzungen für gewebe-engineering
KR20240052847A (ko) 2008-08-20 2024-04-23 셀룰래리티 인코포레이티드 개선된 세포 조성물 및 그의 제조 방법
WO2010021715A1 (en) * 2008-08-20 2010-02-25 Anthrogenesis Corporation Treatment of stroke using isolated placental cells
CA2734446C (en) 2008-08-22 2017-06-20 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
WO2010025530A1 (en) * 2008-09-05 2010-03-11 Universidade Federal Do Rio De Janeiro - Ufrj Proteic acid polymer, production processes, use of proteic acid polymer, pharmaceutical composition and method of treatment
AU2009316541B2 (en) 2008-11-19 2015-08-06 Celularity Inc. Amnion derived adherent cells
US9205177B2 (en) 2009-03-04 2015-12-08 Peytant Solutions, Inc. Stents modified with material comprising amnion tissue and corresponding processes
US8586360B2 (en) 2009-07-02 2013-11-19 Anthrogenesis Corporation Method of producing erythrocytes without feeder cells
US8652500B2 (en) 2009-07-22 2014-02-18 Acell, Inc. Particulate tissue graft with components of differing density and methods of making and using the same
US8298586B2 (en) 2009-07-22 2012-10-30 Acell Inc Variable density tissue graft composition
CN102695723A (zh) 2009-10-30 2012-09-26 中枢神经系统治疗学公司 改进的神经营养因子分子
DK3284818T3 (da) 2010-01-26 2022-06-20 Celularity Inc Behandling af knoglerelateret kræft ved hjælp af placenta stamceller
WO2011099007A1 (en) 2010-02-10 2011-08-18 Nayacure Therapeutics Ltd. Pharmaceutical compositions and methods for the treatment and prevention of cancer
LT2556145T (lt) 2010-04-07 2016-11-10 Anthrogenesis Corporation Angiogenezė naudojant placentos kamienines ląsteles
MX2012011543A (es) 2010-04-08 2013-05-06 Anthrogenesis Corp Tratamiento de sarcoidosis empleando celulas madre placentarias.
ES2666746T3 (es) 2010-07-13 2018-05-07 Anthrogenesis Corporation Métodos para generar linfocitos citolíticos naturales
US20130345140A1 (en) * 2010-08-25 2013-12-26 Lifenet Health Basement Membrane Compositions and Applications Thereof
US8969315B2 (en) 2010-12-31 2015-03-03 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
JP6104896B2 (ja) 2011-06-01 2017-03-29 アントフロゲネシス コーポレーション 胎盤幹細胞を使用する疼痛の治療
EP2717888B1 (de) 2011-06-10 2020-09-09 Tissuetech, Inc. Verfahren zur verarbeitung fötaler gewebesubstrate
WO2013003234A1 (en) * 2011-06-28 2013-01-03 Trevigen, Inc. Tumor extract
WO2013055476A1 (en) 2011-09-09 2013-04-18 Anthrogenesis Corporation Treatment of amyotrophic lateral sclerosis using placental stem cells
EP2594635A1 (de) 2011-11-18 2013-05-22 Univercell Biosolutions Verfahren zur Erzeugung von kardiovaskulären Vorläuferzellen bei Primaten zur Verwendung bei klinischen und arzneimitteltechnischen Zelltests aus embryonalen Primatenstammzellen oder aus Zellen im embryoähnlichen Zustand sowie deren Anwendungen
CA2860227C (en) 2011-12-23 2020-03-24 Pioneer Surgical Technology Continuous matrix with osteoconductive particles dispersed therein, method of forming thereof, and method of regenerating bone therewith
WO2013162828A1 (en) 2012-04-27 2013-10-31 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Use of cpg oligonucleotides co-formulated with an antibiotic to accelarate wound healing
US20140072510A1 (en) * 2012-09-13 2014-03-13 Northwestern University Synthetic Scaffolds for Metastasis Detection
EP2743345A1 (de) 2012-12-13 2014-06-18 IMBA-Institut für Molekulare Biotechnologie GmbH Dreidimensionale heterogen differenzierte Gewebekultur
CN115137753A (zh) 2013-02-05 2022-10-04 细胞结构公司 来自胎盘的自然杀伤细胞
US10405961B2 (en) 2013-03-14 2019-09-10 Cell and Molecular Tissue Engineering, LLC Coated surgical mesh, and corresponding systems and methods
US10130288B2 (en) 2013-03-14 2018-11-20 Cell and Molecular Tissue Engineering, LLC Coated sensors, and corresponding systems and methods
HK1221402A1 (zh) * 2013-04-02 2017-06-02 University Of Florida Research Foundation, Inc. 用於诱导并调节血管生成的组合物和方法以及用於鉴别血管生成调节剂的方法和实验
ES2756531T3 (es) 2013-08-22 2020-04-27 Arch Biosurgery Inc Mallas implantables para controlar el movimiento de fluidos
US9878071B2 (en) 2013-10-16 2018-01-30 Purdue Research Foundation Collagen compositions and methods of use
BR112016016635A2 (pt) 2014-01-22 2017-08-08 Zpredicta Inc Método e aparelho para isolar células invasivas e metastáticas para avaliação terapêutica e previsão de capacidade metastática
WO2015123132A1 (en) * 2014-02-12 2015-08-20 The Board Of Regents Of The University Of Texas System Three-dimensional silk fibroin scaffold culture retaining functional salivary cells and promoting salivary tissue-specific ecm synthesis
JP2017520517A (ja) * 2014-05-08 2017-07-27 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド 持続放出性血管新生調節組成物ならびに血管新生を誘導および調節する方法
EP3185922B1 (de) 2014-08-27 2025-04-02 Purdue Research Foundation Abgabesysteme für therapeutikum auf kollagenbasis
WO2016138025A2 (en) 2015-02-23 2016-09-01 Tissuetech, Inc. Apparatuses and methods for treating ophthalmic diseases and disorders
WO2016146893A1 (en) 2015-03-17 2016-09-22 University Of Oulu Human tumor based extracellular matrix for cell studies in vitro
US11919941B2 (en) 2015-04-21 2024-03-05 Purdue Research Foundation Cell-collagen-silica composites and methods of making and using the same
NL2015130B1 (en) 2015-07-09 2017-02-01 Mimetas B V Barrier function measurements.
US12551509B2 (en) 2015-11-18 2026-02-17 Lucina Patent Holdco, Llc Acellular regenerative products and methods of their manufacture
EP3190176A1 (de) 2016-01-11 2017-07-12 IMBA-Institut für Molekulare Biotechnologie GmbH Verfahren zur gewebekulturentwicklung auf einem gerüst und differenzierte gewebekultur
TW201733600A (zh) 2016-01-29 2017-10-01 帝聖工業公司 胎兒扶持組織物及使用方法
US20190031743A1 (en) 2016-01-29 2019-01-31 Achaogen, Inc. Screening methods for identifying antibodies that bind cell surface epitopes
NL2016404B1 (en) 2016-03-09 2017-09-26 Mimetas B V Double tubular structures.
US10293005B2 (en) 2016-04-19 2019-05-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Use of gram negative species to treat atopic dermatitis
CN109310626A (zh) 2016-04-19 2019-02-05 美利坚合众国,由健康及人类服务部部长代表 革兰氏阴性种治疗特应性皮炎的用途
BR112018075920A2 (pt) 2016-06-15 2019-03-26 Mimetas B.V. dispositivo e métodos de cultura celular
WO2018023129A1 (en) * 2016-07-29 2018-02-01 Zpredicta, Inc. Screening of immuno-modulatory therapies
WO2018140827A1 (en) 2017-01-27 2018-08-02 Achaogen, Inc. Reporter microorganisms and uses thereof
CA3052266A1 (en) 2017-01-31 2018-08-09 Geniphys, Llc Methods and compositions for matrix preparation
US11739291B2 (en) 2017-04-25 2023-08-29 Purdue Research Foundation 3-dimensional (3D) tissue-engineered muscle for tissue restoration
EP3395942A1 (de) 2017-04-25 2018-10-31 IMBA-Institut für Molekulare Biotechnologie GmbH Bi- oder multi-differenziertes organoid
EP3638773A1 (de) 2017-06-16 2020-04-22 IMBA-Institut für Molekulare Biotechnologie GmbH Blutgefäss-organoid, verfahren zur herstellung und verwendung der besagten organoide
CA3074426A1 (en) 2017-09-08 2019-03-14 Sumitomo Dainippon Pharma Co., Ltd. Cell aggregate including retinal tissue and production method therefor
EP3681998A1 (de) 2017-09-11 2020-07-22 IMBA-Institut für Molekulare Biotechnologie GmbH Tumororganoidmodell
WO2019071257A1 (en) 2017-10-06 2019-04-11 The Regents Of The University Of Michigan Office Of Technology Transfer METASTASIC DISEASE DETECTION AND ASSOCIATED METHODS
WO2019083904A1 (en) 2017-10-23 2019-05-02 Chan Zuckerberg Biohub, Inc. AFUCOSYLATED IGG FC GLYCANES MEASUREMENT AND METHODS OF TREATMENT THEREOF
KR20210013080A (ko) 2018-05-11 2021-02-03 포르테 서브시디어리, 인크. 피부 병태의 치료를 위한 조성물
NL2022085B1 (en) 2018-11-28 2020-06-25 Mimetas B V Device for assessing mechanical strain induced in or by cells
GB201900930D0 (en) 2019-01-23 2019-03-13 Res & Innovation Uk Choroid plexus organoids and methods for productions thereof
EP3689971A1 (de) 2019-02-04 2020-08-05 Real Research Sp. z o.o. Proteinhydrogel, herstellungsverfahren und verwendung davon
US12221630B2 (en) 2019-02-19 2025-02-11 Miltenyi Biotec B.V. & Co. KG Cell culture medium and method for generation of epithelial organoids from epithelial stem cells
CA3135546A1 (en) * 2019-04-04 2020-10-08 THT Biomaterials GmbH A novel human-material-based platform technology for tissue engineering
IL271778A (en) 2019-12-31 2021-06-30 Ichilov Tech Ltd Methods for treating atopic dermatitis
EP4096635A4 (de) 2020-01-27 2024-02-21 GeniPhys, Inc. Biologischer füllstoff zur wiederherstellung und regeneration von gewebe
EP4134132A4 (de) * 2020-04-08 2023-09-13 Ichimaru Pharcos Co., Ltd. Einheit zur förderung der angiogenese und/oder nervenregeneration
NL2026038B1 (en) 2020-07-09 2022-03-15 Mimetas B V Microfluidic cell culture device
EP4428227A4 (de) 2021-11-19 2025-11-12 Riken Herstellungsverfahren für blattförmiges netzhautgewebe
EP4286513A1 (de) 2022-06-03 2023-12-06 IMBA-Institut für Molekulare Biotechnologie GmbH Dreifache gewebekulturfusion
CN115261302B (zh) * 2022-07-20 2023-06-06 创芯国际生物科技(广州)有限公司 一种基质胶及其制备方法和应用
JPWO2024204596A1 (de) 2023-03-29 2024-10-03
NL2035770B1 (en) 2023-09-08 2025-03-14 Mimetas B V Titerplate
US20260022331A1 (en) * 2024-07-22 2026-01-22 Preci LLC Methods of producing a tissue derived extracellular matrix hydrogel

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4280954A (en) * 1975-07-15 1981-07-28 Massachusetts Institute Of Technology Crosslinked collagen-mucopolysaccharide composite materials
US4642292A (en) * 1979-10-29 1987-02-10 Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University Method for isolation of connective tissue biomatrix

Also Published As

Publication number Publication date
JPS62129222A (ja) 1987-06-11
EP0218065A3 (en) 1989-03-08
EP0218065A2 (de) 1987-04-15
DE3680851D1 (de) 1991-09-19
US4829000A (en) 1989-05-09
EP0218065B1 (de) 1991-08-14
JPH0740932B2 (ja) 1995-05-10
CA1291432C (en) 1991-10-29

Similar Documents

Publication Publication Date Title
DE3680851D1 (de) Wiederhergestellter basalmembrankomplex mit biologischer aktivitaet.
Campbell et al. Recombinant human interleukin-1 stimulates human articular cartilage to undergo resorption and human chondrocytes to produce both tissue-and urokinase-type plasminogen activator
ATE142691T1 (de) Proteine mit faktor-viii-aktivität, verfahren zu deren herstellung unter verwendung von genetisch modifizierten zellen und diese enthaltende pharmazeutische zusammensetzungen
DE69533223D1 (de) Zusammensetzungen und verfahren zur stimulierung der proliferation und der differenzierung von menschlichen fetalen und erwachsenen pankreatischen zellen ex vivo
DE3878918D1 (de) In-vivo-verabreichung von neurotransmittern durch implantierte eingekapselte zellen.
Yaron et al. Human recombinant interleukin‐1β stimulates glycosaminoglycan production in human synovial fibroblast cultures
Nishiyama et al. Response to growth factors of human dermal fibroblasts in a quiescent state owing to cell-matrix contact inhibition
DE69635924D1 (de) Isolierung und züchtung von schwannzellen
Thawer et al. Effects of electrical stimulation on the histological properties of wounds in diabetic mice
IT1244879B (it) Estratti da tessuti animali, utili in terapia e in diagnostica.
DE69634499D1 (de) Verwendungsmethoden von einkernigen phagozyten zur förderung der axonalen regeneration
ZA895840B (en) N-2,3-butadienyl tri-and tetraaminoalkane derivatives
CN113576971B (zh) 一种纤连蛋白冻干粉制剂及其制备方法
NO882854L (no) Korreksjon med dobbeltraadet rna av avvikende metabolske spor forbundet med ukontrollerte vekstsykluser for tumorceller og virus.
Zelickson et al. Melanocyte changes following PUVA therapy
McGuire et al. Cell-cell interactions in the rheumatoid joint
PT793503E (pt) Uso do factor de crescimento dos hepatocitos para induzir a proliferacao e diferenciacao de celulas henatopoieticas
Cymerman et al. Effects of increased oxygen tensions on bioelectric properties of frog sciatic nerve
FR2600671B1 (fr) Procede de conservation cryogenique de substances et matieres organiques, notamment de cellules
BR9709379A (pt) Uso de uridina, e, composição para o tratamento de distúrbios do sistema nervoso devido à degeneração seletiva de células neuroniais ou gliais em mamìferos.
Shinmei et al. N6, O2′-dibutyryl adenosine 3′, 5′-monophosphate-stimulated release of proteoglycans from cultured immature rabbit ear cartilage
DAHLLÖF et al. Synthesis of sulfated glycosaminoglycans by human gingival fibroblasts from phenytoin‐induced gingival overgrowth in vitro
Kashket et al. Electron microscopic observations of the saliva-dependent aggregation of oral streptococci
Guin et al. Electrophoretic characterization of plasma RNA
EP0246518A3 (de) Unterlage für Zellkulturen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time