ATE66930T1 - Methode zur aufloesung und naturation von somatotropin. - Google Patents

Methode zur aufloesung und naturation von somatotropin.

Info

Publication number: ATE66930T1
Authority: AT; Austria
Prior art keywords: naturation; somatotropin; solution; protein; dissolution
Prior art date: 1985-02-22

Application number

AT86870023T

Other languages

English (en)

Inventor

Larry Andrew Bentle

James William Mitchell

Stephen Bradley Storrs

Grant Tsuyoshi Shimamoto

Original Assignee

Monsanto Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-02-22

Filing date

1986-02-21

Publication date

1991-09-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27107301&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE66930(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1985-02-22 Priority claimed from US06/704,677 external-priority patent/US4652630A/en

1986-02-21 Application filed by Monsanto Co filed Critical Monsanto Co

1991-09-15 Application granted granted Critical

1991-09-15 Publication of ATE66930T1 publication Critical patent/ATE66930T1/de

Links

102000018997 Growth Hormone Human genes 0.000 title abstract 4
108010051696 Growth Hormone Proteins 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 3
238000004090 dissolution Methods 0.000 title 1
102000004169 proteins and genes Human genes 0.000 abstract 4
108090000623 proteins and genes Proteins 0.000 abstract 4
HHVIBTZHLRERCL-UHFFFAOYSA-N sulfonyldimethane Chemical compound CS(C)(=O)=O HHVIBTZHLRERCL-UHFFFAOYSA-N 0.000 abstract 4
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 2
239000004202 carbamide Substances 0.000 abstract 2
230000015572 biosynthetic process Effects 0.000 abstract 1
239000003638 chemical reducing agent Substances 0.000 abstract 1
239000007800 oxidant agent Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
230000007928 solubilization Effects 0.000 abstract 1
238000005063 solubilization Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Wood Science & Technology (AREA)
Endocrinology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Toxicology (AREA)
Biomedical Technology (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Beans For Foods Or Fodder (AREA)
Cosmetics (AREA)
Dental Preparations (AREA)

AT86870023T 1985-02-22 1986-02-21 Methode zur aufloesung und naturation von somatotropin. ATE66930T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US70434185A	1985-02-22	1985-02-22
US06/704,677 US4652630A (en)	1985-02-22	1985-02-22	Method of somatotropin naturation
EP86870023A EP0192629B2 (de)	1985-02-22	1986-02-21	Methode zur Auflösung und Naturation von Somatotropin

Publications (1)

Publication Number	Publication Date
ATE66930T1 true ATE66930T1 (de)	1991-09-15

Family

ID=27107301

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86870023T ATE66930T1 (de)	1985-02-22	1986-02-21	Methode zur aufloesung und naturation von somatotropin.

Country Status (14)

Country	Link
EP (1)	EP0192629B2 (de)
JP (1)	JP2572963B2 (de)
KR (1)	KR890003082B1 (de)
CN (1)	CN1010097B (de)
AT (1)	ATE66930T1 (de)
AU (3)	AU587423B2 (de)
CA (1)	CA1268300A (de)
DE (1)	DE3681185D1 (de)
DK (1)	DK172526B1 (de)
ES (1)	ES8800957A1 (de)
IE (1)	IE58871B1 (de)
IL (1)	IL77951A (de)
NZ (1)	NZ215259A (de)
SU (1)	SU1542402A3 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU612133B2 (en) *	1987-02-20	1991-07-04	Natinco Nv	Production of proteins in active forms
US4985544A (en) *	1987-08-04	1991-01-15	Kyowa Hakko Kogyo Co., Ltd.	Process for renaturing fish growth hormone
JP2669859B2 (ja) *	1987-08-04	1997-10-29	協和醗酵工業株式会社	タンパク質の再活性化法
JPH01132598A (ja) *	1987-10-14	1989-05-25	Pitman Moore Inc	変性剤溶液中に含まれる組換え蛋白質における分子内ジスルフィド結合の生成を促進する方法
JPH01257491A (ja) *	1988-04-08	1989-10-13	Tosoh Corp	不溶性融合異種蛋白質の処理方法
US5089473A (en)	1988-08-29	1992-02-18	Monsanto Company	Somatotropin variants and their use
DE3835350A1 (de) *	1988-10-17	1990-04-19	Boehringer Mannheim Gmbh	Aktivierung von gentechnologisch hergestellten, in prokaryonten exprimierten antikoerpern
US5064943A (en) *	1988-12-16	1991-11-12	American Cyanamid Company	Method for solubilization and naturation of somatotropin
JP2517100B2 (ja) *	1989-03-08	1996-07-24	協和醗酵工業株式会社	ヒト顆粒球コロニ―刺激因子活性を有する蛋白質の精製法
US5182369A (en) *	1990-02-28	1993-01-26	Monsanto Company	Method for purifying somatotropin monomers
US5023323A (en) *	1990-09-12	1991-06-11	Monsanto Company	Method of somatotropin naturation
AU2592395A (en) *	1994-05-19	1995-12-18	Monsanto Company	Method for purifying somatotropin monomers
AU3109795A (en) *	1994-07-25	1996-02-22	Novartis Ag	Process for folding of proteins like recombinant hirudin or epidermal growth factor
ZA9711733B (en)	1996-12-31	1998-07-01	Monsanto Co	Method for solubilization and naturation of somatotropins
EP0984789A2 (de) *	1997-06-27	2000-03-15	Monsanto Company	Somatotropin zur beschleunigung des wachstums eines tierischen hufs
WO2007014170A2 (en) *	2005-07-25	2007-02-01	Trubion Pharmaceuticals, Inc.	Compositions and methods for protein deaggregation
JP4766052B2 (ja)	2005-11-24	2011-09-07	株式会社村田製作所	電気音響変換器
BRPI0621124A2 (pt)	2005-12-22	2011-11-29	Genentech Inc	métodos para recuperação de uma proteìna de ligação à heparina
AR062069A1 (es) *	2006-07-14	2008-10-15	Genentech Inc	Replegado de proteinas recombinantes
US11959125B2 (en)	2016-09-15	2024-04-16	Sun Genomics, Inc.	Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
EP3512946A4 (de) *	2016-09-15	2020-04-08	Sun Genomics Inc.	Universelles verfahren zur extraktion von nukleinsäuren aus einer unterschiedlichen population von einer oder mehreren arten von mikroben in einer probe

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE55163B1 (en) *	1982-06-07	1990-06-20	Celltech Ltd	A process for the preparation of chymosin
GR79124B (de) *	1982-12-22	1984-10-02	Genentech Inc
EP0122080B1 (de) *	1983-03-25	1989-09-13	Celltech Limited	Verfahren zur Herstellung eines Proteins

1986
- 1986-02-20 ES ES552233A patent/ES8800957A1/es not_active Expired
- 1986-02-21 AU AU53853/86A patent/AU587423B2/en not_active Ceased
- 1986-02-21 DE DE8686870023T patent/DE3681185D1/de not_active Expired - Lifetime
- 1986-02-21 KR KR1019860001222A patent/KR890003082B1/ko not_active Expired
- 1986-02-21 CA CA000502494A patent/CA1268300A/en not_active Expired - Lifetime
- 1986-02-21 DK DK198600809A patent/DK172526B1/da not_active IP Right Cessation
- 1986-02-21 CN CN86100915A patent/CN1010097B/zh not_active Expired
- 1986-02-21 NZ NZ215259A patent/NZ215259A/xx unknown
- 1986-02-21 JP JP61037159A patent/JP2572963B2/ja not_active Expired - Lifetime
- 1986-02-21 SU SU4022043A patent/SU1542402A3/ru active
- 1986-02-21 EP EP86870023A patent/EP0192629B2/de not_active Expired - Lifetime
- 1986-02-21 IL IL77951A patent/IL77951A/xx not_active IP Right Cessation
- 1986-02-21 AT AT86870023T patent/ATE66930T1/de not_active IP Right Cessation
- 1986-02-24 IE IE46686A patent/IE58871B1/en not_active IP Right Cessation
1989
- 1989-05-19 AU AU34980/89A patent/AU621111B2/en not_active Ceased
- 1989-08-03 AU AU39258/89A patent/AU618386B2/en not_active Ceased

Also Published As

Publication number	Publication date
DK80986D0 (da)	1986-02-21
CA1268300C (en)	1990-04-24
IE58871B1 (en)	1993-11-17
JP2572963B2 (ja)	1997-01-16
EP0192629A2 (de)	1986-08-27
AU587423B2 (en)	1989-08-17
AU3925889A (en)	1990-04-05
CN86100915A (zh)	1986-08-20
AU5385386A (en)	1986-08-28
IE860466L (en)	1986-08-22
DK172526B1 (da)	1998-11-16
ES552233A0 (es)	1987-12-01
SU1542402A3 (ru)	1990-02-07
AU621111B2 (en)	1992-03-05
NZ215259A (en)	1989-11-28
EP0192629B1 (de)	1991-09-04
EP0192629A3 (en)	1988-07-27
EP0192629B2 (de)	1997-03-05
KR860006541A (ko)	1986-09-13
AU3498089A (en)	1989-09-14
DK80986A (da)	1986-08-23
CA1268300A (en)	1990-04-24
JPS61195698A (ja)	1986-08-29
KR890003082B1 (ko)	1989-08-21
AU618386B2 (en)	1991-12-19
IL77951A (en)	1990-11-05
DE3681185D1 (de)	1991-10-10
ES8800957A1 (es)	1987-12-01
CN1010097B (zh)	1990-10-24

Legal Events

Date	Code	Title
1992-04-15	UEP	Publication of translation of european patent specification
1998-01-15	UEP	Publication of translation of european patent specification
2003-12-15	EEIH	Change in the person of patent owner
2006-05-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
ATE66930T1 (de)	1991-09-15	Methode zur aufloesung und naturation von somatotropin.
US4530787B1 (de)	1993-07-20
DE10075008I2 (de)	2004-10-21	Analoga von Insulin und deren Herstellungsmethode.
DE3686654D1 (de)	1992-10-08	Verfahren zur isolierung rekombinanter polypeptide in biologisch aktiver form.
BR8805865A (pt)	1989-08-01	Composicao;composicao supercondutora;e metodo para preparar uma pasta semifluida de carbonatos mistos de l,m,a,substancialmente livres de ions que nao sejam carbonato de l,m,a,cloreto e ions gerados por agua
ATE95522T1 (de)	1993-10-15	Verfahren zur herstellung von des-b30-insulinen und des-b30-insulinderivaten.
ATE45388T1 (de)	1989-08-15	Verfahren zur fluessig-fluessig-extraktion von germanium oder indium aus waessrigen loesungen.
IL82091A (en)	1991-12-15	Process for renaturing proteins
FI860566A0 (fi)	1986-02-07	Foerfarande foer framstaellning av skummande blandningar.
WO1987000204A3 (en)	1987-03-12	Purification of somatotropin from transformed microorganisms
NO863571D0 (no)	1986-09-08	Fremgangsmaate for behandling av sjeldne jordartsmineraler.
ATE113060T1 (de)	1994-11-15	Methode zur auflösung und naturation von somatotropin unter verwendung von einer niedrigen harnstoffkonzentration.
DE3779063D1 (de)	1992-06-17	Verfahren zur stabilisierung von waesserigen phosphoenolbrenztraubensaeureloesungen und container dafuer.
DE3685714D1 (de)	1992-07-23	Verfahren zur herstellung einer einseitig gequetschten metallhalogenidhochdruckentladungslampe und eine nach diesem verfahren hergestellte lampe.
ATE48616T1 (de)	1989-12-15	Analoge von hypokalzemischen polypeptiden, welche den kalziumgehalt des koerpers schonen, deren herstellung, deren verwendung als arznei und diese enthaltende zusammensetzungen.
HUT40140A (en)	1986-11-28	Process for solubilizing and restoring homatropin
SU1172283A1 (ru)	1999-12-20	Способ переработки молибденсодержащих продуктов
SU1297464A1 (ru)	1999-12-20	Способ вскрытия молибденсодержащих руд
SU1534814A1 (ru)	2000-05-10	Способ очистки газов от оксидов азота