ATE67401T1 - SOFT SEAMLESS CAPSULES. - Google Patents

SOFT SEAMLESS CAPSULES.

Info

Publication number
ATE67401T1
ATE67401T1 AT86117918T AT86117918T ATE67401T1 AT E67401 T1 ATE67401 T1 AT E67401T1 AT 86117918 T AT86117918 T AT 86117918T AT 86117918 T AT86117918 T AT 86117918T AT E67401 T1 ATE67401 T1 AT E67401T1
Authority
AT
Austria
Prior art keywords
stream
composite jet
film
forming
cells
Prior art date
Application number
AT86117918T
Other languages
German (de)
Inventor
Tadashi Kosaka
Kazuki Omata
Tatsuo Hashimoto
Teruaki Yamazaki
Kazuo Hayashi
Tomiya Hosoi
Kenichi Ikuta
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE67401T1 publication Critical patent/ATE67401T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Rigid Containers With Two Or More Constituent Elements (AREA)
  • Wrappers (AREA)

Abstract

A soft capsule composed of a plurality of cells coalesced to each other and filling substances encapsulated in the individual cells, the wall of at least one of the cells being formed of a material different from a material forming the wall of at least one of the other cells, and said capsule being seamless. The soft capsule can be produced by (a) preparing a plurality of composite jet streams each consisting of a stream of a film-forming liquid substance for forming a cell wall and within said stream of a film-forming liquid substance a single stream, or a plurality of independent streams, of a filling substance having flowability, the film-forming liquid subtance in at least one of the composite jet streams being different from the film-forming liquid substance in at least one of the other composite jet streams, (b) advancing the plurality of composite jet streams in closely spaced relationship into and through a stream of a liquid medium substantially incapable of dissolving the film-forming liquid substance in the flowing direction of the liquid medium stream, (c) coalescing the adjacent composite jet streams to each other to form a single composite jet stream in the liquid medium stream, (d) cutting the single composite jet stream to a predetermined length successively from its leading end in the liquid medium stream, and (e) solidifying the cell walls of the resulting soft capsule.
AT86117918T 1985-12-26 1986-12-23 SOFT SEAMLESS CAPSULES. ATE67401T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP29718285 1985-12-26
EP86117918A EP0228067B1 (en) 1985-12-26 1986-12-23 Seamless soft capsule

Publications (1)

Publication Number Publication Date
ATE67401T1 true ATE67401T1 (en) 1991-10-15

Family

ID=17843233

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86117918T ATE67401T1 (en) 1985-12-26 1986-12-23 SOFT SEAMLESS CAPSULES.

Country Status (6)

Country Link
EP (1) EP0228067B1 (en)
JP (1) JPH06104193B2 (en)
AT (1) ATE67401T1 (en)
DE (1) DE3681572D1 (en)
ES (1) ES2024418B3 (en)
GR (1) GR3002754T3 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5800829A (en) * 1991-04-25 1998-09-01 Brown University Research Foundation Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
SG47470A1 (en) * 1991-04-25 1998-04-17 Univ Brown Res Found Implantable biocompatible immunoisolatory vehicle for delivery of a selected therapeutic products
GB2338896B (en) 1998-07-02 2003-05-21 Reckitt & Colmann Prod Ltd Chewable Capsules
NZ516733A (en) 1999-07-30 2004-03-26 Smithkline Beecham Plc Pharmaceutical formulations for oral dosing that are dosage forms comprising two or more connected sub-units
CN1109627C (en) * 2000-01-26 2003-05-28 依钟康 Soft capsule for packing different material and its production equipment and method
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
GB0102342D0 (en) 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US7670612B2 (en) 2002-04-10 2010-03-02 Innercap Technologies, Inc. Multi-phase, multi-compartment capsular delivery apparatus and methods for using same
WO2003094897A1 (en) * 2002-05-09 2003-11-20 Chugai Seiyaku Kabushiki Kaisha Photostabilized soft capsule
US7025911B2 (en) 2002-09-13 2006-04-11 Freund Corporation Manufacturing method for oral quick-dissolving seamless capsule
JP2004105282A (en) * 2002-09-13 2004-04-08 Freunt Ind Co Ltd Method for producing seamless capsule with rapid dissolution in the oral cavity
JP2006521366A (en) * 2003-03-28 2006-09-21 シグモイド・バイオテクノロジーズ・リミテッド Solid oral dosage forms containing seamless microcapsules
TW200526274A (en) 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
EP1690518A4 (en) * 2003-11-07 2008-12-31 Freund Corp METHOD AND DEVICE FOR PRODUCING SOLDER-FREE CAPSULES, AND SOLDER-FREE CAPSULE
PE20060003A1 (en) 2004-03-12 2006-03-01 Smithkline Beecham Plc POLYMERIC PHARMACEUTICAL FORMULATION FOR INJECTION MOLDING
US20070134493A1 (en) * 2005-12-08 2007-06-14 Kanji Meghpara Compositions and capsules with stable hydrophilic layers
JP5183104B2 (en) * 2006-06-19 2013-04-17 森下仁丹株式会社 Multiple soft capsules for bad breath removal
JP2010500091A (en) * 2006-08-09 2010-01-07 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ Apparatus and method for activating physiologically effective substance by ultrasound and capsule
JP2009119148A (en) * 2007-11-16 2009-06-04 Freunt Ind Co Ltd Multicolor seamless capsule manufacturing apparatus and manufacturing method
WO2013073676A1 (en) * 2011-11-16 2013-05-23 森下仁丹株式会社 Pest control agent
JP6091679B1 (en) * 2016-03-29 2017-03-08 株式会社松風 Droplet generator

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59131355A (en) * 1983-01-17 1984-07-28 森下仁丹株式会社 Multiple soft capsule

Also Published As

Publication number Publication date
JPS62234542A (en) 1987-10-14
EP0228067A2 (en) 1987-07-08
EP0228067A3 (en) 1988-06-01
EP0228067B1 (en) 1991-09-18
GR3002754T3 (en) 1993-01-25
DE3681572D1 (en) 1991-10-24
JPH06104193B2 (en) 1994-12-21
ES2024418B3 (en) 1992-03-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee