ATE67479T1 - Ester von salsalat mit guajakol zur behandlung von phlogistischen bronchopneumopathien. - Google Patents
Ester von salsalat mit guajakol zur behandlung von phlogistischen bronchopneumopathien.Info
- Publication number
- ATE67479T1 ATE67479T1 AT87108737T AT87108737T ATE67479T1 AT E67479 T1 ATE67479 T1 AT E67479T1 AT 87108737 T AT87108737 T AT 87108737T AT 87108737 T AT87108737 T AT 87108737T AT E67479 T1 ATE67479 T1 AT E67479T1
- Authority
- AT
- Austria
- Prior art keywords
- esters
- bronchopneumopathies
- phlogistic
- treatment
- guajakol
- Prior art date
Links
- 150000002148 esters Chemical class 0.000 title abstract 3
- LHGVFZTZFXWLCP-UHFFFAOYSA-N guaiacol Chemical compound COC1=CC=CC=C1O LHGVFZTZFXWLCP-UHFFFAOYSA-N 0.000 title abstract 3
- 240000008415 Lactuca sativa Species 0.000 title 1
- 235000012045 salad Nutrition 0.000 title 1
- WVYADZUPLLSGPU-UHFFFAOYSA-N salsalate Chemical compound OC(=O)C1=CC=CC=C1OC(=O)C1=CC=CC=C1O WVYADZUPLLSGPU-UHFFFAOYSA-N 0.000 abstract 2
- 206010053582 Bronchopneumopathy Diseases 0.000 abstract 1
- TUCNEACPLKLKNU-UHFFFAOYSA-N acetyl Chemical compound C[C]=O TUCNEACPLKLKNU-UHFFFAOYSA-N 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 229940124584 antitussives Drugs 0.000 abstract 1
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 229960001867 guaiacol Drugs 0.000 abstract 1
- 229960000953 salsalate Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/90—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified hydroxyl and carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8621021A IT1213579B (it) | 1986-07-03 | 1986-07-03 | Flogistica. esteri di salsalato con guaiacolo atti al trattamento di broncopneumapatie a base |
| EP87108737A EP0251039B1 (de) | 1986-07-03 | 1987-06-18 | Ester von Salsalat mit Guajakol zur Behandlung von phlogistischen Bronchopneumopathien |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE67479T1 true ATE67479T1 (de) | 1991-10-15 |
Family
ID=11175501
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87108737T ATE67479T1 (de) | 1986-07-03 | 1987-06-18 | Ester von salsalat mit guajakol zur behandlung von phlogistischen bronchopneumopathien. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4743704A (de) |
| EP (1) | EP0251039B1 (de) |
| JP (1) | JPS6322541A (de) |
| AT (1) | ATE67479T1 (de) |
| DE (1) | DE3773059D1 (de) |
| ES (1) | ES2026485T3 (de) |
| IT (1) | IT1213579B (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6538033B2 (en) | 2000-08-29 | 2003-03-25 | Huntington Medical Research Institutes | Nitric oxide donor compounds |
| US20090221703A1 (en) | 2006-07-09 | 2009-09-03 | Chongxi Yu | High penetration composition and uses thereof |
| US20090238763A1 (en) | 2006-07-09 | 2009-09-24 | Chongxi Yu | High penetration compositions and uses thereof |
| AU2006346195B2 (en) | 2006-07-09 | 2013-03-07 | Techfields Biochem Co. Ltd | Positively charged water-soluble prodrugs of aspirin |
| KR20210103586A (ko) | 2007-06-04 | 2021-08-23 | 테크필즈 인크 | 매우 높은 피부 및 막 침투율을 가지는 비스테로이드성 소염제(ｎｓａｉａ) 약물전구체 및 이들의 새로운 의약적 용도 |
| RU2630577C2 (ru) | 2008-12-04 | 2017-09-11 | Чунси ЮЙ | Композиции интенсивного проникновения и их применение |
| CN116898848A (zh) | 2012-01-18 | 2023-10-20 | 苏州泰飞尔医药有限公司 | 治疗肺部疾病的高穿透力前药组合物和医药组合物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU446324B2 (en) * | 1971-02-04 | 1974-02-27 | Beecham Inc. | Chemical processes and products |
| BE787198A (fr) * | 1971-08-07 | 1973-02-05 | Merck Patent Gmbh | Composes et melanges nematiques |
| JPS4954340A (de) * | 1972-09-28 | 1974-05-27 | ||
| IT1101712B (it) * | 1978-11-16 | 1985-10-07 | Bayer Italia Spa | Procedimento perfezionato per la preparazione di guaiacolo acetil-salicilato |
| IT1144813B (it) * | 1981-06-22 | 1986-10-29 | Unione Chimica Medicamenti Dif | Acetilsalicilato di 2 o metossi fenossi etanolo ad attivita analgesica antipiretica ed antiflogistica e suo metodo di preparazione |
| US4483854A (en) * | 1983-04-12 | 1984-11-20 | Key Pharmaceuticals, Inc. | Systemic treatment of psoriasis using certain salicylates |
-
1986
- 1986-07-03 IT IT8621021A patent/IT1213579B/it active
-
1987
- 1987-06-18 EP EP87108737A patent/EP0251039B1/de not_active Expired - Lifetime
- 1987-06-18 ES ES198787108737T patent/ES2026485T3/es not_active Expired - Lifetime
- 1987-06-18 DE DE8787108737T patent/DE3773059D1/de not_active Expired - Fee Related
- 1987-06-18 AT AT87108737T patent/ATE67479T1/de active
- 1987-06-19 US US07/063,995 patent/US4743704A/en not_active Expired - Fee Related
- 1987-07-03 JP JP62165545A patent/JPS6322541A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IT8621021A0 (it) | 1986-07-03 |
| IT1213579B (it) | 1989-12-20 |
| JPS6322541A (ja) | 1988-01-30 |
| EP0251039B1 (de) | 1991-09-18 |
| EP0251039A1 (de) | 1988-01-07 |
| ES2026485T3 (es) | 1992-05-01 |
| DE3773059D1 (de) | 1991-10-24 |
| US4743704A (en) | 1988-05-10 |
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