ATE6863T1 - Dipeptid-derivate von 5-0,6-0-acyl-2-amin-2desoxy-d-glucofuranose und verfahren zur herstellung. - Google Patents

Dipeptid-derivate von 5-0,6-0-acyl-2-amin-2desoxy-d-glucofuranose und verfahren zur herstellung.

Info

Publication number
ATE6863T1
ATE6863T1 AT81400675T AT81400675T ATE6863T1 AT E6863 T1 ATE6863 T1 AT E6863T1 AT 81400675 T AT81400675 T AT 81400675T AT 81400675 T AT81400675 T AT 81400675T AT E6863 T1 ATE6863 T1 AT E6863T1
Authority
AT
Austria
Prior art keywords
hydrogen
alkyl
2desoxy
glucofuranose
acyl
Prior art date
Application number
AT81400675T
Other languages
English (en)
Inventor
Philippe L. Durette
Original Assignee
Merck & Co. Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. Inc. filed Critical Merck & Co. Inc.
Application granted granted Critical
Publication of ATE6863T1 publication Critical patent/ATE6863T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrrole Compounds (AREA)
AT81400675T 1980-05-05 1981-04-29 Dipeptid-derivate von 5-0,6-0-acyl-2-amin-2desoxy-d-glucofuranose und verfahren zur herstellung. ATE6863T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/146,806 US4310514A (en) 1980-05-05 1980-05-05 Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose derivatives and methods of preparation
EP81400675A EP0039637B1 (de) 1980-05-05 1981-04-29 Dipeptid-Derivate von 5-0,6-0-Acyl-2-amin-2-desoxy-D-glucofuranose und Verfahren zur Herstellung

Publications (1)

Publication Number Publication Date
ATE6863T1 true ATE6863T1 (de) 1984-04-15

Family

ID=22519075

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81400675T ATE6863T1 (de) 1980-05-05 1981-04-29 Dipeptid-derivate von 5-0,6-0-acyl-2-amin-2desoxy-d-glucofuranose und verfahren zur herstellung.

Country Status (10)

Country Link
US (1) US4310514A (de)
EP (1) EP0039637B1 (de)
JP (1) JPS56169697A (de)
AT (1) ATE6863T1 (de)
CA (1) CA1175804A (de)
DE (1) DE3162856D1 (de)
DK (1) DK197181A (de)
ES (1) ES8207552A1 (de)
GR (1) GR75655B (de)
PT (1) PT72925B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4397844A (en) * 1978-02-24 1983-08-09 Ciba-Geigy Corporation Antigen derivatives and processes for their preparation
US4356170A (en) * 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
US5370871A (en) * 1983-01-24 1994-12-06 The Johns Hopkins University Therapeutic suppression of specific immune responses by administration of oligomeric forms of antigen of controlled chemistry
US6022544A (en) 1983-01-24 2000-02-08 The John Hopkins University Therapeutic suppression of specific immune responses by administration of oligomeric forms of antigen of controlled chemistry
US5126131A (en) * 1983-01-24 1992-06-30 The Johns Hopkins University Therapeutic suppression of specific immune responses by administration of antigen-competitive conjugates.
FR2564096B1 (fr) * 1984-05-11 1988-02-19 Anvar Derives lipophiles de muramylpeptides ayant des proprietes d'activation des macrophages, compositions les contenant et procede pour les obtenir
US4866036A (en) * 1987-10-05 1989-09-12 Merck & Co., Inc. Dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose compositions and methods of use in aids-immunocompromised human hosts
US5089470A (en) * 1988-08-26 1992-02-18 The United State Of America As Represented By The United States Department Of Energy Compositions containing poly (γ-glutamylcysteinyl)glycines
DE69111401T2 (de) * 1990-12-21 1996-02-22 Pliva Pharm & Chem Works Tert-Butyloxycarbonyl-L-Tyrosyl-Peptidoglycanmonomer und deren 125 I-markiertes Derivat, deren Herstellung und Verwendung.
AU2657495A (en) * 1994-05-23 1995-12-18 Research And Development Institute, Inc. Candida albicans adhesin as a vaccine
US6309642B1 (en) 1997-04-28 2001-10-30 The Research And Development Institute, Inc. Peptides which mimic candida carbohydrate epitopes and their use in a vaccine
US6488929B2 (en) 1994-05-23 2002-12-03 Montana State University Candida albicans phosphomannan complex as a vaccine
US20030072775A1 (en) * 1997-04-28 2003-04-17 The Research And Development Institute Inc. Peptides which mimic candida carbohydrate epitopes and their use in a vaccine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2248025A2 (en) 1973-10-23 1975-05-16 Anvar Vaccine compsns. - contg. N-acyl muramic acid deriv. as adjuvant
FR2288527A2 (fr) 1974-10-22 1976-05-21 Anvar Compositions contenant de la n-acetyl-muramyl- l-alanyl - d-isoglutamine ou de l'acide n-acetyl-muramyl-l-alanyl - d-glutamique, exemptes d'huile et ayant des proprietes adjuvantes
FR2326930A1 (fr) * 1975-10-09 1977-05-06 Anvar Agents hydrosolubles depresseurs non specifiques des reponses immunitaires
CH613709A5 (en) 1975-12-10 1979-10-15 Ciba Geigy Ag Process for the preparation of glucosamine derivatives
US4153684A (en) * 1976-03-10 1979-05-08 Agence Nationale De Valorisation De La Recherche (Anvar) Immunizing and anti-infectious adjuvant agents constituted by N-acetyl-muramyl-L-alanyl-D-glutamic acid derivatives
US4082736A (en) * 1976-04-26 1978-04-04 Syntex (U.S.A.) Inc. Novel immunological adjuvant compounds and methods of preparation thereof
US4082735A (en) * 1976-04-26 1978-04-04 Syntex (U.S.A.) Inc. Novel immunological adjuvant compounds and methods of preparation thereof
GB1563561A (en) * 1976-06-23 1980-03-26 Daiichi Seiyaku Co Muramyldipeptide derivatives and process for the preparation thereof

Also Published As

Publication number Publication date
PT72925B (en) 1985-11-25
JPS56169697A (en) 1981-12-26
PT72925A (en) 1981-05-01
DK197181A (da) 1981-12-11
EP0039637A1 (de) 1981-11-11
CA1175804A (en) 1984-10-09
US4310514A (en) 1982-01-12
EP0039637B1 (de) 1984-03-28
ES501865A0 (es) 1982-10-01
ES8207552A1 (es) 1982-10-01
DE3162856D1 (en) 1984-05-03
GR75655B (de) 1984-08-02

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee