ATE69052T1 - Polymorphe form des famotidins und ihr herstellungsverfahren. - Google Patents

Polymorphe form des famotidins und ihr herstellungsverfahren.

Info

Publication number
ATE69052T1
ATE69052T1 AT88500054T AT88500054T ATE69052T1 AT E69052 T1 ATE69052 T1 AT E69052T1 AT 88500054 T AT88500054 T AT 88500054T AT 88500054 T AT88500054 T AT 88500054T AT E69052 T1 ATE69052 T1 AT E69052T1
Authority
AT
Austria
Prior art keywords
famotidine
production process
polymorphous form
preparation
melting point
Prior art date
Application number
AT88500054T
Other languages
English (en)
Inventor
Montserrat Ballester-Rodes
Francisco Eugen Palomo-Nicolau
Antonio Luis Palomo-Coll
Original Assignee
Marga Investigacion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27240404&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE69052(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from ES8702020A external-priority patent/ES2009147A6/es
Priority claimed from ES8703326A external-priority patent/ES2015339A6/es
Priority claimed from ES8800888A external-priority patent/ES2017246A6/es
Application filed by Marga Investigacion filed Critical Marga Investigacion
Application granted granted Critical
Publication of ATE69052T1 publication Critical patent/ATE69052T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Electron Beam Exposure (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pyridine Compounds (AREA)
  • Saccharide Compounds (AREA)
AT88500054T 1987-06-22 1988-06-01 Polymorphe form des famotidins und ihr herstellungsverfahren. ATE69052T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ES8702020A ES2009147A6 (es) 1987-06-22 1987-06-22 Nuevo proceso para la preparacion de polimorfos de famotidina
ES8703326A ES2015339A6 (es) 1987-10-29 1987-10-29 Perfeccionamientos a la patente de invencion numero 8702020 por nuevo proceso para la preparacion de polimorfos de famotidina.
ES8800888A ES2017246A6 (es) 1988-03-23 1988-03-23 Mejoras a la patente de invencion, numero 8702020 por nuevo proceso para la preparacion de polimorfos de famotidina.
EP88500054A EP0297019B1 (de) 1987-06-22 1988-06-01 Polymorphe Form des Famotidins und ihr Herstellungsverfahren

Publications (1)

Publication Number Publication Date
ATE69052T1 true ATE69052T1 (de) 1991-11-15

Family

ID=27240404

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88500054T ATE69052T1 (de) 1987-06-22 1988-06-01 Polymorphe form des famotidins und ihr herstellungsverfahren.

Country Status (13)

Country Link
US (1) US5021582A (de)
EP (1) EP0297019B1 (de)
JP (1) JPH01100162A (de)
KR (1) KR920000308B1 (de)
CN (1) CN1030077A (de)
AT (1) ATE69052T1 (de)
AU (1) AU1767288A (de)
CA (1) CA1322760C (de)
DE (1) DE3865899D1 (de)
DK (1) DK342988A (de)
FI (1) FI882329A7 (de)
IL (1) IL86330A0 (de)
NO (1) NO882037L (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196775B (en) * 1986-08-05 1989-01-30 Richter Gedeon Vegyeszet Process for production of morfologically unique new modifications of famotidin and medical compositions containing such substances
US5631023A (en) * 1993-07-09 1997-05-20 R.P. Scherer Corporation Method for making freeze dried drug dosage forms
EP0844997A1 (de) * 1996-06-19 1998-06-03 Dr. Reddy's Research Foundation Neue polymorphe formen des troglitazons die eine erhöhte anti-diabetische wirkung besitzen und verfahren zu ihrer herstellung
RU2192251C1 (ru) * 2001-05-25 2002-11-10 Дальневосточный государственный медицинский университет Способ снижения гликемии у больных сахарным диабетом ii типа с гастродуоденальными язвами
JP4755789B2 (ja) * 2001-09-26 2011-08-24 株式会社フジシールインターナショナル ラベル及びその製造方法
CA2426122A1 (en) * 2002-05-02 2003-11-02 M/S Tonira Pharma Limited A process for the preparation of a combination of famotidine polymorphis a and b
US8058296B2 (en) * 2008-11-25 2011-11-15 Richard Tokunaga Treatment and prevention of deleterious effects associated with alcohol consumption
CN117534630B (zh) * 2022-08-02 2025-11-18 重庆世森医药科技有限公司 一种高纯度法莫替丁精制得b晶型的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4496737A (en) * 1982-09-27 1985-01-29 Merck & Co., Inc. Process for preparing sulfamylamidine antisecretory agents
JPS59227870A (ja) * 1983-06-07 1984-12-21 Yamanouchi Pharmaceut Co Ltd 新規２−グアニジノチアゾリン誘導体ならびにその製造法
HU194845B (en) * 1985-09-11 1988-03-28 Richter Gedeon Vegyeszet Process for production of n-sulphamil-3-/2-guanidintiazolil-4-methil-tio/-propion-amidin
DE3644246A1 (de) * 1986-06-20 1987-12-23 Uriach & Cia Sa J Verfahren zur herstelung von 3-(((2-((aminoiminomethyl)-amino)-4-thiazolyl)-methyl)-thio)-n-(aminosulfonyl)-propanimidamid
HU196775B (en) * 1986-08-05 1989-01-30 Richter Gedeon Vegyeszet Process for production of morfologically unique new modifications of famotidin and medical compositions containing such substances

Also Published As

Publication number Publication date
DE3865899D1 (de) 1991-12-05
CA1322760C (en) 1993-10-05
EP0297019A1 (de) 1988-12-28
FI882329A7 (fi) 1988-12-23
DK342988A (da) 1988-12-23
KR920000308B1 (ko) 1992-01-11
US5021582A (en) 1991-06-04
IL86330A0 (en) 1988-11-15
EP0297019B1 (de) 1991-10-30
DK342988D0 (da) 1988-06-22
CN1030077A (zh) 1989-01-04
NO882037L (no) 1988-12-23
KR890000086A (ko) 1989-03-11
FI882329A0 (fi) 1988-05-18
NO882037D0 (no) 1988-05-10
JPH01100162A (ja) 1989-04-18
AU1767288A (en) 1988-12-22

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties