ATE70180T1 - Aerosolmittel zur nasenverstaeubung von vitamin b 12. - Google Patents

Aerosolmittel zur nasenverstaeubung von vitamin b 12.

Info

Publication number: ATE70180T1
Authority: AT; Austria
Prior art keywords: vitamin; aerosol; dusting; nose; administration
Prior art date: 1985-04-16

Application number

AT86902640T

Other languages

English (en)

Inventor

Jeffrey Wenig

Original Assignee

Nastech Pharm Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-16

Filing date

1986-04-02

Publication date

1991-12-15

1986-04-02 Application filed by Nastech Pharm Co filed Critical Nastech Pharm Co

1991-12-15 Application granted granted Critical

1991-12-15 Publication of ATE70180T1 publication Critical patent/ATE70180T1/de

Links

239000000443 aerosol Substances 0.000 title abstract 2
229940088594 vitamin Drugs 0.000 title 1
229930003231 vitamin Natural products 0.000 title 1
235000013343 vitamin Nutrition 0.000 title 1
239000011782 vitamin Substances 0.000 title 1
150000003722 vitamin derivatives Chemical class 0.000 title 1
229930003779 Vitamin B12 Natural products 0.000 abstract 1
FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000011715 vitamin B12 Substances 0.000 abstract 1
235000019163 vitamin B12 Nutrition 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Otolaryngology (AREA)
Molecular Biology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT86902640T 1985-04-16 1986-04-02 Aerosolmittel zur nasenverstaeubung von vitamin b 12. ATE70180T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US72385985A	1985-04-16	1985-04-16
EP86902640A EP0218679B1 (de)	1985-04-16	1986-04-02	Aerosolmittel zur nasenverstäubung von vitamin b 12
PCT/US1986/000665 WO1986005987A1 (en)	1985-04-16	1986-04-02	Aerosol compositions for nasal delivery of vitamin b12

Publications (1)

Publication Number	Publication Date
ATE70180T1 true ATE70180T1 (de)	1991-12-15

Family

ID=24907989

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86902640T ATE70180T1 (de)	1985-04-16	1986-04-02	Aerosolmittel zur nasenverstaeubung von vitamin b 12.

Country Status (6)

Country	Link
EP (1)	EP0218679B1 (de)
JP (1)	JPS62500788A (de)
AT (1)	ATE70180T1 (de)
CA (1)	CA1317881C (de)
DE (1)	DE3682862D1 (de)
WO (1)	WO1986005987A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2216794B (en) *	1988-03-22	1991-11-20	Fisons Plc	Pharmaceuticals compositions
JPH05213759A (ja) *	1992-02-05	1993-08-24	All Yakuhin Kogyo Kk	安定なビタミンｂ１２含有内用液剤
WO1994013252A1 (en) *	1992-12-10	1994-06-23	Hemogen, Inc.	Method for stimulating production of heme oxygenase using vitamin b12
ES2074396B1 (es) *	1993-03-24	1996-04-01	Farmalider Sa	Sistema de administracion nasal de cianocobalamina (vitamina b12).
BE1007839A6 (nl) *	1993-12-20	1995-10-31	Merkus Franciscus W H M Prof	Farmaceutische compositie voor de nasale toediening van hydroxocobalamine.
US5925625A (en) *	1994-05-13	1999-07-20	Merkus; Franciscus W. H. M.	Pharmaceutical composition for the intranasal administration of hydroxocobalamin
US7404489B1 (en)	2003-03-04	2008-07-29	Qol Medical, Llc	Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
US7229636B1 (en)	2003-03-04	2007-06-12	Nastech Pharmaceutical Company Inc.	Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
WO2006020291A2 (en) *	2004-08-02	2006-02-23	Bebaas, Inc.	Vitamin b12 compositions
JP2009504767A (ja)	2005-08-17	2009-02-05	フレミング・アンド・カンパニー・ファーマシューティカルズ	ビタミンｂ１２鼻用スプレーおよび使用方法
US20130131007A1 (en)	2005-09-07	2013-05-23	Bebaas, Inc.	Vitamin b12 compositions
AU2014202415B2 (en) *	2006-06-23	2016-02-18	Par Pharmaceutical, Inc	Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
CN101600729A (zh) *	2006-06-23	2009-12-09	帕尔医疗公司	用于鼻内递送的氰钴胺低粘度水性制剂
JP5515198B2 (ja) *	2007-05-09	2014-06-11	大正製薬株式会社	メコバラミン含有粉体
JP5797227B2 (ja) *	2013-05-21	2015-10-21	パルファーマシューティカル，インコーポレーテッド	鼻内送達用シアノコバラミン低粘度水性製剤
JP6097787B2 (ja) *	2015-06-09	2017-03-15	パルファーマシューティカル，インコーポレーテッド	鼻内送達用シアノコバラミン低粘度水性製剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2746796A (en) *	1953-08-05	1956-05-22	Pharma Craft Corp	Metering valve aerosol bottle
US2914222A (en) *	1957-05-20	1959-11-24	Meshberg Philip	Aerosol package
US4525341A (en) *	1984-04-09	1985-06-25	Mayor Pharmaceutical Laboratories, Inc.	Method of administering vitamins

1986
- 1986-04-02 DE DE8686902640T patent/DE3682862D1/de not_active Expired - Lifetime
- 1986-04-02 AT AT86902640T patent/ATE70180T1/de active
- 1986-04-02 JP JP61502169A patent/JPS62500788A/ja active Pending
- 1986-04-02 WO PCT/US1986/000665 patent/WO1986005987A1/en not_active Ceased
- 1986-04-02 EP EP86902640A patent/EP0218679B1/de not_active Expired - Lifetime
- 1986-04-16 CA CA000506798A patent/CA1317881C/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0218679A4 (de)	1987-10-08
CA1317881C (en)	1993-05-18
EP0218679A1 (de)	1987-04-22
JPS62500788A (ja)	1987-04-02
DE3682862D1 (de)	1992-01-23
EP0218679B1 (de)	1991-12-11
WO1986005987A1 (en)	1986-10-23

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