ATE71366T1 - Prostaglandinderivate, verfahren zu ihrer herstellung und deren pharmazeutische zusammensetzungen. - Google Patents

Prostaglandinderivate, verfahren zu ihrer herstellung und deren pharmazeutische zusammensetzungen.

Info

Publication number
ATE71366T1
ATE71366T1 AT88908640T AT88908640T ATE71366T1 AT E71366 T1 ATE71366 T1 AT E71366T1 AT 88908640 T AT88908640 T AT 88908640T AT 88908640 T AT88908640 T AT 88908640T AT E71366 T1 ATE71366 T1 AT E71366T1
Authority
AT
Austria
Prior art keywords
prostagland
individuals
processes
production
pharmaceutical compositions
Prior art date
Application number
AT88908640T
Other languages
English (en)
Inventor
Umberto Valcavi
Original Assignee
Istituto Biochimico Italiano
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Biochimico Italiano filed Critical Istituto Biochimico Italiano
Application granted granted Critical
Publication of ATE71366T1 publication Critical patent/ATE71366T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic
    • C07C35/06—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic containing a five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/26—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C47/267—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups containing rings other than six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
AT88908640T 1987-06-25 1988-02-10 Prostaglandinderivate, verfahren zu ihrer herstellung und deren pharmazeutische zusammensetzungen. ATE71366T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT21055/87A IT1205183B (it) 1987-06-25 1987-06-25 Derivati prostaglandinici,procedimenti per prepararli e composizioni farmaceutiche che li contengono
PCT/IT1988/000010 WO1988010252A1 (en) 1987-06-25 1988-02-10 Prostaglandin derivates, their process and pharmaceutical compositions
EP88908640A EP0319576B1 (de) 1987-06-25 1988-02-10 Prostaglandinderivate, verfahren zu ihrer herstellung und deren pharmazeutische zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE71366T1 true ATE71366T1 (de) 1992-01-15

Family

ID=11176047

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88908640T ATE71366T1 (de) 1987-06-25 1988-02-10 Prostaglandinderivate, verfahren zu ihrer herstellung und deren pharmazeutische zusammensetzungen.

Country Status (12)

Country Link
EP (1) EP0319576B1 (de)
KR (1) KR890701556A (de)
AT (1) ATE71366T1 (de)
AU (1) AU598647B2 (de)
DE (1) DE3867610D1 (de)
DK (1) DK85489D0 (de)
ES (1) ES2011833A6 (de)
GR (1) GR1000026B (de)
IT (1) IT1205183B (de)
NO (1) NO890806D0 (de)
WO (1) WO1988010252A1 (de)
ZA (1) ZA881451B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990003170A2 (en) * 1988-09-20 1990-04-05 Ibi Istituto Biochimico Italiano Giovanni Lorenzini S.P.A. Prostaglandin-derivatives having antithrombotic activity
US5011141A (en) * 1990-02-28 1991-04-30 Lumex, Inc. Bench press with adjustable safety/range limiting bars
US5385945A (en) * 1992-10-21 1995-01-31 Allergan, Inc. 7-(5-substituted cyclopentyl) and (5-substituted cyclopentenyl) heptyl alcohols, heptylamines and heptanoic acid amides, and method of lowering intraocular pressure in the eye of a mammal by administration of these novel compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1060366B (it) * 1974-08-07 1982-07-10 Istituto Biochimico Italiano Acidi 19.20 bis nor prostanoici come composti ipolipemici
IT1190400B (it) * 1985-10-04 1988-02-16 Istituto Biochimico Italiano Derivati dell'acido 19,20-bis,nor-prostanoico ad attivita' antiulcera e anoressivca,procedimento per la loro preparazione e composizioni farmaceutiche

Also Published As

Publication number Publication date
WO1988010252A1 (en) 1988-12-29
AU1291188A (en) 1989-01-19
IT1205183B (it) 1989-03-15
DK85489A (da) 1989-02-23
DK85489D0 (da) 1989-02-23
NO890806L (no) 1989-02-24
KR890701556A (ko) 1989-12-20
IT8721055A0 (it) 1987-06-25
AU598647B2 (en) 1990-06-28
EP0319576B1 (de) 1992-01-08
GR1000026B (el) 1990-01-31
ZA881451B (en) 1988-08-23
ES2011833A6 (es) 1990-02-16
NO890806D0 (no) 1989-02-24
DE3867610D1 (de) 1992-02-20
GR880100165A (en) 1989-03-08
EP0319576A1 (de) 1989-06-14

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee