ATE72432T1 - Forskolinderivate. - Google Patents

Forskolinderivate.

Info

Publication number
ATE72432T1
ATE72432T1 AT86115846T AT86115846T ATE72432T1 AT E72432 T1 ATE72432 T1 AT E72432T1 AT 86115846 T AT86115846 T AT 86115846T AT 86115846 T AT86115846 T AT 86115846T AT E72432 T1 ATE72432 T1 AT E72432T1
Authority
AT
Austria
Prior art keywords
sup
sub
denotes
hydrogen
denotes hydrogen
Prior art date
Application number
AT86115846T
Other languages
English (en)
Inventor
Tochiro Tatee
Takashi Takahira
Kouwa Yamashita
Masao Sakurai
Akira Shiozawa
Kazuhisa Narita
Original Assignee
Nippon Kayaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Kayaku Kk filed Critical Nippon Kayaku Kk
Application granted granted Critical
Publication of ATE72432T1 publication Critical patent/ATE72432T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT86115846T 1985-11-15 1986-11-14 Forskolinderivate. ATE72432T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP25469385 1985-11-15
JP1377186 1986-01-27
JP5370986 1986-03-13
JP6594786 1986-03-26
EP86115846A EP0222413B1 (de) 1985-11-15 1986-11-14 Forskolinderivate

Publications (1)

Publication Number Publication Date
ATE72432T1 true ATE72432T1 (de) 1992-02-15

Family

ID=27456077

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86115846T ATE72432T1 (de) 1985-11-15 1986-11-14 Forskolinderivate.

Country Status (10)

Country Link
US (1) US4954642A (de)
EP (1) EP0222413B1 (de)
KR (1) KR930009795B1 (de)
CN (1) CN1016507B (de)
AT (1) ATE72432T1 (de)
AU (1) AU591196B2 (de)
CA (1) CA1337527C (de)
DE (1) DE3683828D1 (de)
ES (1) ES2037656T3 (de)
HU (1) HU202515B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN163242B (de) * 1985-05-03 1988-08-27 Hoechst India
DE3623300A1 (de) * 1986-07-11 1988-01-21 Hoechst Ag 7-acyloxy-6-aminoacyloxypolyoxylabdane, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
IN166900B (de) * 1987-06-03 1990-08-04 Hoechst India
DE3887212T2 (de) * 1987-06-29 1994-06-01 Nippon Kayaku Kk Verfahren zur Herstellung von Derivaten von 6,7-Diazyl-7-desacetylforskolin.
US5302730A (en) * 1987-06-29 1994-04-12 Nippon Kayaku Kk Process for the preparation of 6,7-diacyl-7-deacetylforskolin derivatives
DE3737353A1 (de) * 1987-11-04 1989-05-18 Hoechst Ag Neue acyllabdan-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
IN168181B (de) * 1987-12-01 1991-02-16 Hoechst India
US5051132A (en) * 1989-06-15 1991-09-24 Nippon Kayaku Kabushiki Kaisha Lyophilized preparation of 6-(3-dimethylaminopropionyl)forskolin
EP0447962A1 (de) * 1990-03-17 1991-09-25 Hoechst Aktiengesellschaft Labdane und Verfahren zu ihrer Herstellung
EP0650723A3 (de) * 1990-03-23 1995-08-30 Nippon Kayaku Kk Neue pharmazeutische Verwendungen von Forskolin-Derivaten.
JPH0482885A (ja) * 1990-07-23 1992-03-16 Nippon Kayaku Co Ltd ６―アシル―７―デアセチルフォルスコリン誘導体の新規な製造法
RU2034840C1 (ru) * 1990-07-24 1995-05-10 Хехст АГ СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ 6-бета-(3-ЗАМЕЩЕННОГО АМИНО)-ПРОПИОНИЛОКСИ-7-ДИАЦЕТИЛФОРСКОЛИНА ИЛИ ИХ ФАРМАЦЕВТИЧЕСКИ ПРИЕМЛЕМЫХ СОЛЕЙ
PL170900B1 (pl) * 1990-11-01 1997-02-28 Nippon Kayaku Kk Sposób wytwarzania 6-(3-dwumetyloaminopropionylo)-forskolinu PL PL PL
ES2065842B1 (es) * 1993-03-10 1996-02-16 Univ Granada Aplicacion de ent-3b,6b,12b-trihidroxi-13-epi-oxido de manoilo como activador de la adenilatociclasa
ES2065844B1 (es) * 1993-03-10 1996-02-16 Univ Granada Aplicacion de ent-16,18-dihidroxi-6-oxo-oxido de manoilo como inhibidor de la adenilatociclasa.
ES2065843B1 (es) * 1993-03-10 1996-02-16 Univ Granada Aplicacion de ent-11 , 16-dihidroxi-18-nor-4a -carboximetil-oxido de manoilo como inhibidor de la adenilatociclasa.
US6737084B2 (en) 2000-06-27 2004-05-18 Qualilife Compositions and methods for enhancing or treating female sexual response
AU2014305843B2 (en) 2013-08-09 2019-08-29 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
CN105693684B (zh) * 2016-01-22 2018-10-09 昆明医科大学 一种异佛司可林的制备方法
AU2019414693A1 (en) 2018-12-29 2021-08-12 Shanghai Archeus Biotech Co., Ltd. Immunosuppressive pharmaceutical composition and application thereof
EP4706758A3 (de) 2019-05-21 2026-05-06 Ardelyx, Inc. Verfahren zur hemmung des phosphattransports
CN117586217B (zh) * 2024-01-17 2024-03-19 云南省药物研究所 一种基于国产毛喉鞘蕊花的佛司可林制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2557784C2 (de) * 1975-12-22 1986-04-17 Hoechst Ag, 6230 Frankfurt Forskolin, Verfahren zu dessen Gewinnung und diese Verbindung enthaltende pharmazeutische Präparate
DE2654796A1 (de) * 1976-12-03 1978-06-08 Hoechst Ag Polyoxygenierte labdan-derivate
US4517200A (en) * 1982-12-27 1985-05-14 Schering-Plough Corporation Method for treating allergic reactions with forskolin
AU2690684A (en) * 1984-02-24 1985-09-10 Kenji Adachi Methods and pharmaceutical compositions for the treatment of hyperplastic diseases of the skin
US4639446A (en) * 1984-12-14 1987-01-27 Hoechst-Roussel Pharmaceuticals Inc. Aminoacyllabdanes, pharmaceutical compositions and use
EP0191166B1 (de) * 1984-12-14 1991-02-06 Hoechst-Roussel Pharmaceuticals Incorporated Aminoacyllabdane, Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US4639443A (en) * 1985-03-01 1987-01-27 Hoechst-Roussel Pharmaceuticals Inc. Labdane compounds, pharmaceutical compositions and use
ATE62683T1 (de) * 1985-03-01 1991-05-15 Hoechst Roussel Pharma Labdanderivate, verfahren zu deren herstellung und deren verwendung als arzneimittel.
IN163242B (de) * 1985-05-03 1988-08-27 Hoechst India
US4785040A (en) * 1985-10-04 1988-11-15 Occidental Chemical Corporation Phenolic molding materials and processes
DE3623300A1 (de) * 1986-07-11 1988-01-21 Hoechst Ag 7-acyloxy-6-aminoacyloxypolyoxylabdane, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4871764A (en) * 1986-11-20 1989-10-03 Hoechst-Roussel Pharmaceuticals, Inc. 12-Halogenated forskolin derivatives
CA1307530C (en) * 1986-12-29 1992-09-15 Hoechst-Roussel Pharmaceuticals Inc. Carbamoyloxylabdanes, intermediates and a process for the preparation thereof and their use as medicaments
JP3503980B2 (ja) * 1993-02-23 2004-03-08 株式会社東芝 データ読出し用半導体集積回路

Also Published As

Publication number Publication date
CN86107826A (zh) 1987-10-14
EP0222413A3 (en) 1987-07-22
AU6510786A (en) 1987-05-21
KR930009795B1 (ko) 1993-10-11
EP0222413A2 (de) 1987-05-20
HU202515B (en) 1991-03-28
HUT46317A (en) 1988-10-28
KR870005005A (ko) 1987-06-04
ES2037656T3 (es) 1993-07-01
CA1337527C (en) 1995-11-07
CN1016507B (zh) 1992-05-06
AU591196B2 (en) 1989-11-30
US4954642A (en) 1990-09-04
DE3683828D1 (de) 1992-03-19
EP0222413B1 (de) 1992-02-05

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee