ATE74269T1 - Zellproliferationsinhibitor. - Google Patents

Zellproliferationsinhibitor.

Info

Publication number
ATE74269T1
ATE74269T1 AT88306963T AT88306963T ATE74269T1 AT E74269 T1 ATE74269 T1 AT E74269T1 AT 88306963 T AT88306963 T AT 88306963T AT 88306963 T AT88306963 T AT 88306963T AT E74269 T1 ATE74269 T1 AT E74269T1
Authority
AT
Austria
Prior art keywords
cell proliferation
proliferation inhibitor
inhibitor
chem
integer
Prior art date
Application number
AT88306963T
Other languages
English (en)
Inventor
Naoto Hashimoto
Kaneyoshi Kato
Yoshio Kozai
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE74269T1 publication Critical patent/ATE74269T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
AT88306963T 1987-07-29 1988-07-28 Zellproliferationsinhibitor. ATE74269T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18914387 1987-07-29
EP19880306963 EP0301861B1 (de) 1987-07-29 1988-07-28 Zellproliferationsinhibitor

Publications (1)

Publication Number Publication Date
ATE74269T1 true ATE74269T1 (de) 1992-04-15

Family

ID=16236136

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88306963T ATE74269T1 (de) 1987-07-29 1988-07-28 Zellproliferationsinhibitor.

Country Status (4)

Country Link
EP (1) EP0301861B1 (de)
AT (1) ATE74269T1 (de)
CA (1) CA1317962C (de)
DE (1) DE3869692D1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3065636B2 (ja) * 1989-06-29 2000-07-17 塩野義製薬株式会社 ［ジ―ｔｅｒｔ―ブチル（ヒドロキシ）フェニルチオ］置換ヒドロキサム酸誘導体
DK0614455T3 (da) * 1991-11-07 1996-03-18 Res Inst Medicine Chem Vitamin D-amidderivater
US5804601A (en) * 1995-04-10 1998-09-08 Takeda Chemical Industries, Ltd. Aromatic hydroxamic acid compounds, their production and use
WO1996040623A1 (en) * 1995-06-07 1996-12-19 Teva Pharmaceutical Industries Ltd. 2-substituted 1,8-dihydroxy-9(10h)-antracenone as proliferation and 5-lipoxygenase inhibitors
US5891916A (en) * 1995-06-21 1999-04-06 Takeda Chemical Industries, Ltd. Aromatic hydroxamix acid compounds, their production and use
GB0023983D0 (en) 2000-09-29 2000-11-15 Prolifix Ltd Therapeutic compounds
ATE310719T1 (de) 2000-09-29 2005-12-15 Topotarget Uk Ltd Carbaminsäurederivate enthaltend eine amidgruppe als hdac-inhibitoren
US6888027B2 (en) 2000-09-29 2005-05-03 Topotarget Uk Limited Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors
AR043850A1 (es) * 2003-04-17 2005-08-17 Bayer Pharmaceuticals Corp Acidos hidroxamicos utiles en el tratamiento de trastornos hiperproliferativos
JP5725299B2 (ja) * 2008-03-26 2015-05-27 サントル ナショナル ドゥ ラ ルシェルシュ シアンティフィク １，４−ナフトキノン誘導体およびその治療用途
BR112013030370A2 (pt) 2011-05-26 2017-08-08 Apex Therapeutics Inc compostos de quinona para tratamento de doenças mediadas por ape1
WO2012167122A1 (en) 2011-06-03 2012-12-06 Indiana University Research And Technology Corporation Compounds, compositions and methods for treating oxidative dna damage disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2242077B1 (de) * 1973-09-03 1977-01-28 Roussel Uclaf
JPS58174313A (ja) * 1982-04-06 1983-10-13 Takeda Chem Ind Ltd 動物組織の線維化抑制剤
JPS58177934A (ja) * 1982-04-13 1983-10-18 Takeda Chem Ind Ltd ベンゾキノン誘導体
MX9203040A (es) * 1984-08-01 1992-07-31 Takeda Chemical Industries Ltd Derivados de quinona y composicion farmaceutica que los contiene.
EP0232089B1 (de) * 1986-01-28 1991-03-13 Takeda Chemical Industries, Ltd. Chinonamide, deren Herstellung und Anwendung
IL81264A (en) * 1986-01-30 1990-11-05 Takeda Chemical Industries Ltd Quinone derivatives,their production and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0301861A1 (de) 1989-02-01
CA1317962C (en) 1993-05-18
EP0301861B1 (de) 1992-04-01
DE3869692D1 (de) 1992-05-07

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties