ATE76096T1 - Verfahren und vorrichtung fuer enzymatische synthese. - Google Patents

Verfahren und vorrichtung fuer enzymatische synthese.

Info

Publication number: ATE76096T1
Authority: AT; Austria
Prior art keywords: product; enzymatic synthesis; synthetic; arte; equilibria
Prior art date: 1985-01-15

Application number

AT86300161T

Other languages

English (en)

Inventor

Bradley Richard Snedecor

Chung Chih Hsu

Original Assignee

Genentech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-01-15

Filing date

1986-01-13

Publication date

1992-05-15

1986-01-13 Application filed by Genentech Inc filed Critical Genentech Inc

1992-05-15 Application granted granted Critical

1992-05-15 Publication of ATE76096T1 publication Critical patent/ATE76096T1/de

Links

238000000034 method Methods 0.000 title abstract 2
230000015572 biosynthetic process Effects 0.000 title 1
230000002255 enzymatic effect Effects 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1
239000000047 product Substances 0.000 abstract 3
YZQCXOFQZKCETR-UWVGGRQHSA-N Asp-Phe Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 YZQCXOFQZKCETR-UWVGGRQHSA-N 0.000 abstract 1
125000005907 alkyl ester group Chemical group 0.000 abstract 1
239000006227 byproduct Substances 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
238000000909 electrodialysis Methods 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
238000011084 recovery Methods 0.000 abstract 1
231100000331 toxic Toxicity 0.000 abstract 1
230000002588 toxic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Wood Science & Technology (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biotechnology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Microbiology (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)

AT86300161T 1985-01-15 1986-01-13 Verfahren und vorrichtung fuer enzymatische synthese. ATE76096T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US69168985A	1985-01-15	1985-01-15
EP86300161A EP0188342B1 (de)	1985-01-15	1986-01-13	Verfahren und Vorrichtung für enzymatische Synthese

Publications (1)

Publication Number	Publication Date
ATE76096T1 true ATE76096T1 (de)	1992-05-15

Family

ID=24777560

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86300161T ATE76096T1 (de)	1985-01-15	1986-01-13	Verfahren und vorrichtung fuer enzymatische synthese.

Country Status (10)

Country	Link
EP (1)	EP0188342B1 (de)
JP (1)	JPS61205490A (de)
AT (1)	ATE76096T1 (de)
AU (1)	AU598452B2 (de)
CA (1)	CA1309681C (de)
DE (1)	DE3685223D1 (de)
DK (1)	DK16286A (de)
IE (1)	IE58291B1 (de)
IL (1)	IL77584A (de)
ZA (1)	ZA86269B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5336601A (en) *	1986-08-18	1994-08-09	The Coca-Cola Company	Enzymatic membrane method for the snythesis and separation of peptides
US5350681A (en) *	1986-08-18	1994-09-27	The Coca-Cola Company	Enzymatic membrane method for the synthesis and separation of peptides
US5202235A (en) *	1986-08-18	1993-04-13	The Coca-Cola Company	Enzymatic method for the synthesis and separation of peptides
US5037741A (en) *	1986-08-18	1991-08-06	The Coca Cola Company	Enzymatic method for the synthesis and separation of peptides
US5002871A (en) *	1986-08-18	1991-03-26	The Coca-Cola Company	Enzymatic membrane method for the synthesis and separation of peptides
FI915012A0 (fi) *	1989-04-24	1991-10-23	Coca Cola Co	Enzymatiskt membranfoerfarande foer syntetisering och separering av peptider.
US5714465A (en)	1989-05-19	1998-02-03	Amgen Inc.	Method of inhibiting tumor cell dissemination with a metalloproteinase inhibitor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH490305A (fr) *	1967-03-28	1970-05-15	Politechnika Slaska Im Wincent	Procédé de fabrication d'acides carboxyliques
JPS52136985A (en) *	1976-05-07	1977-11-16	Ajinomoto Co Inc	Fermentation and dialysis
US4506011A (en) *	1981-09-05	1985-03-19	Toyo Soda Manufacturing Co., Ltd.	Process for preparation of aspartylphenylalanine alkyl esters

1986
- 1986-01-13 AU AU52225/86A patent/AU598452B2/en not_active Expired
- 1986-01-13 DE DE8686300161T patent/DE3685223D1/de not_active Expired - Lifetime
- 1986-01-13 IL IL77584A patent/IL77584A/xx not_active IP Right Cessation
- 1986-01-13 AT AT86300161T patent/ATE76096T1/de active
- 1986-01-13 EP EP86300161A patent/EP0188342B1/de not_active Expired - Lifetime
- 1986-01-14 ZA ZA86269A patent/ZA86269B/xx unknown
- 1986-01-14 IE IE10286A patent/IE58291B1/en not_active IP Right Cessation
- 1986-01-14 DK DK16286A patent/DK16286A/da not_active Application Discontinuation
- 1986-01-14 JP JP61006132A patent/JPS61205490A/ja active Pending
- 1986-01-15 CA CA000499619A patent/CA1309681C/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE3685223D1 (de)	1992-06-17
DK16286D0 (da)	1986-01-14
EP0188342A3 (en)	1988-03-30
IE58291B1 (en)	1993-08-25
EP0188342B1 (de)	1992-05-13
ZA86269B (en)	1987-09-30
EP0188342A2 (de)	1986-07-23
CA1309681C (en)	1992-11-03
AU5222586A (en)	1986-07-24
IE860102L (en)	1986-07-15
JPS61205490A (ja)	1986-09-11
AU598452B2 (en)	1990-06-28
IL77584A (en)	1989-10-31
DK16286A (da)	1986-07-16

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