ATE76290T1 - Galenische formen mit verzoegerter verapamilfreisetzung, deren herstellung und diese enthaltende arzneimittel. - Google Patents
Galenische formen mit verzoegerter verapamilfreisetzung, deren herstellung und diese enthaltende arzneimittel.Info
- Publication number
- ATE76290T1 ATE76290T1 AT86870136T AT86870136T ATE76290T1 AT E76290 T1 ATE76290 T1 AT E76290T1 AT 86870136 T AT86870136 T AT 86870136T AT 86870136 T AT86870136 T AT 86870136T AT E76290 T1 ATE76290 T1 AT E76290T1
- Authority
- AT
- Austria
- Prior art keywords
- verapamil
- delayed
- preparation
- pharmaceuticals containing
- galenical forms
- Prior art date
Links
- SGTNSNPWRIOYBX-UHFFFAOYSA-N 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile Chemical compound C1=C(OC)C(OC)=CC=C1CCN(C)CCCC(C#N)(C(C)C)C1=CC=C(OC)C(OC)=C1 SGTNSNPWRIOYBX-UHFFFAOYSA-N 0.000 title abstract 3
- 229960001722 verapamil Drugs 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000000945 filler Substances 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 210000000936 intestine Anatomy 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 125000005395 methacrylic acid group Chemical group 0.000 abstract 1
- 239000012982 microporous membrane Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000004014 plasticizer Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU86099A LU86099A1 (fr) | 1985-09-30 | 1985-09-30 | Formes galeniques a liberation prolongee du verapamil,leur fabrication et medicaments les contenant |
| EP86870136A EP0217778B1 (de) | 1985-09-30 | 1986-09-25 | Galenische Formen mit verzögerter Verapamil-Freisetzung, deren Herstellung und diese enthaltende Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE76290T1 true ATE76290T1 (de) | 1992-06-15 |
Family
ID=19730554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86870136T ATE76290T1 (de) | 1985-09-30 | 1986-09-25 | Galenische formen mit verzoegerter verapamilfreisetzung, deren herstellung und diese enthaltende arzneimittel. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4832958A (de) |
| EP (1) | EP0217778B1 (de) |
| AT (1) | ATE76290T1 (de) |
| DE (1) | DE3685392D1 (de) |
| LU (1) | LU86099A1 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5254347A (en) * | 1988-03-31 | 1993-10-19 | Tanabe Seiyaku Co., Ltd. | Controlled release pharmaceutical preparation and method for producing the same |
| FI101344B1 (fi) * | 1988-03-31 | 1998-06-15 | Tanabe Seiyaku Co | Menetelmä valmistaa valmiste, josta kontrolloidusti vapautuu farmaseuttisesti aktiivista ainetta |
| DE3932378A1 (de) * | 1989-09-28 | 1991-04-11 | Knoll Ag | Feste arzneiform mit hohem verapamil-gehalt |
| US5364635A (en) * | 1989-09-28 | 1994-11-15 | Knoll Ag | Solid drug form with a high verapamil content |
| US5252337A (en) * | 1991-06-25 | 1993-10-12 | Eurand America, Inc. | Controlled release calcium channel blocker microcapsules |
| US5288505A (en) * | 1991-06-26 | 1994-02-22 | Galephar P.R., Inc., Ltd. | Extended release form of diltiazem |
| BE1006990A5 (nl) * | 1993-04-22 | 1995-02-07 | Univ Gent | Werkwijze en samenstelling om een aktief bestanddeel in een vaste toedieningsvorm te brengen. |
| DK0797987T3 (da) * | 1994-12-19 | 2004-02-16 | Daiichi Seiyaku Co | Granulært præparat med langvarig frigivelse og fremgangsmåde til fremstilling deraf |
| US5695781A (en) * | 1995-03-01 | 1997-12-09 | Hallmark Pharmaceuticals, Inc. | Sustained release formulation containing three different types of polymers |
| US6083532A (en) * | 1995-03-01 | 2000-07-04 | Duramed Pharmaceuticals, Inc. | Sustained release formulation containing three different types of polymers and tablet formed therefrom |
| US6607751B1 (en) * | 1997-10-10 | 2003-08-19 | Intellipharamaceutics Corp. | Controlled release delivery device for pharmaceutical agents incorporating microbial polysaccharide gum |
| WO2001015668A1 (en) | 1999-09-02 | 2001-03-08 | Nostrum Pharmaceuticals, Inc. | Controlled release pellet formulation |
| US7108866B1 (en) | 1999-12-10 | 2006-09-19 | Biovall Laboratories International Srl | Chronotherapeutic diltiazem formulations and the administration thereof |
| US20060153914A1 (en) * | 1999-12-10 | 2006-07-13 | Biovail Laboratories International S.R.L. | Chronotherapeutic diltiazem formulations and the administration thereof |
| US20030195706A1 (en) * | 2000-11-20 | 2003-10-16 | Michael Korenberg | Method for classifying genetic data |
| US6676958B2 (en) * | 2001-06-19 | 2004-01-13 | Advanced Bioadjuvants, Llc | Adjuvant composition for mucosal and injection delivered vaccines |
| US8101209B2 (en) * | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
| US20040005359A1 (en) * | 2002-06-27 | 2004-01-08 | Cheng Xiu Xiu | Controlled release oral dosage form |
| FR2845289B1 (fr) * | 2002-10-04 | 2004-12-03 | Ethypharm Sa | Spheroides, procede de preparation et compositions pharmaceutiques. |
| EP2112920B1 (de) * | 2003-06-26 | 2018-07-25 | Intellipharmaceutics Corp. | Protonenpumpeninhibitoren enthaltende kapseln, die verschieden aufgebaute untereinheiten zur verzögerten wirkstofffreisetzung enthalten |
| US8394409B2 (en) * | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
| US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
| US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
| WO2007112581A1 (en) * | 2006-04-03 | 2007-10-11 | Isa Odidi | Controlled release delivery device comprising an organosol coat |
| US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
| US20080292663A1 (en) * | 2007-05-22 | 2008-11-27 | Gerber Jay D | Adjuvant compositions and methods for delivering vaccines |
| US20110150986A1 (en) * | 2009-12-18 | 2011-06-23 | Kristin Arnold | Quinine formulations, method of making, and metho of use thereof |
| WO2011083150A2 (en) * | 2010-01-07 | 2011-07-14 | Akron Molecules Gmbh | Obesity small molecules |
| GB201003734D0 (en) | 2010-03-05 | 2010-04-21 | Univ Strathclyde | Delayed prolonged drug delivery |
| GB201003731D0 (en) | 2010-03-05 | 2010-04-21 | Univ Strathclyde | Immediate/delayed drug delivery |
| GB201003766D0 (en) | 2010-03-05 | 2010-04-21 | Univ Strathclyde | Pulsatile drug release |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3113901A1 (de) * | 1981-04-07 | 1982-10-28 | Basf Ag, 6700 Ludwigshafen | Wirkstoffzubereitung zur oralen applikation |
| LU85058A1 (fr) * | 1983-10-24 | 1985-06-19 | Pharlyse | Comprimes pharmaceutiques a liberation prolongee,leur preparation et leur utilisation |
| DK62184D0 (da) * | 1984-02-10 | 1984-02-10 | Benzon As Alfred | Diffusionsovertrukket polydepotpraeparat |
-
1985
- 1985-09-30 LU LU86099A patent/LU86099A1/fr unknown
-
1986
- 1986-09-25 DE DE8686870136T patent/DE3685392D1/de not_active Expired - Fee Related
- 1986-09-25 EP EP86870136A patent/EP0217778B1/de not_active Expired - Lifetime
- 1986-09-25 AT AT86870136T patent/ATE76290T1/de active
- 1986-09-30 US US06/913,279 patent/US4832958A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE3685392D1 (de) | 1992-06-25 |
| EP0217778A2 (de) | 1987-04-08 |
| US4832958A (en) | 1989-05-23 |
| EP0217778A3 (en) | 1987-12-09 |
| EP0217778B1 (de) | 1992-05-20 |
| LU86099A1 (fr) | 1987-04-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE76290T1 (de) | Galenische formen mit verzoegerter verapamilfreisetzung, deren herstellung und diese enthaltende arzneimittel. | |
| AU6770490A (en) | Solid pharmaceutical compositions containing cimetidine | |
| DE3363321D1 (en) | Long-lasting three layered pharmaceutical film preparations | |
| ATE72975T1 (de) | Arzneimittel mit gesteuerter absorption. | |
| TNSN98229A1 (fr) | Formulation pharmaceutique orale a liberation prolongee | |
| ATE246505T1 (de) | Zubereitung enthaltend cefaclor oder cephalexin mit modifizierter freisetzungsmatrix | |
| ES2036457A1 (es) | Forma de dosificacion farmaceutica solida oral de liberacion programada y procedimiento de preparacion. | |
| JPS6245536A (ja) | 鼻、口、舌下および膣腔の粘膜から薬剤を供給する吸収増強剤としてのコリンエステル類 | |
| EP0013000A3 (en) | Polymeric agent for releasing 5-aminosalicylic acid or its derivatives into the gastrointestinal tract, pharmaceutical formulation comprising said agent,method of its preparation and method of preparing said formulation | |
| DE69623087D1 (de) | Brausemittel und dessen Herstellung | |
| DE3686936D1 (de) | Am zielorgan wirkendes enterales abgabesystem. | |
| ATE30380T1 (de) | Pharmazeutische formulierungen mit mehrfachen einheiten. | |
| CA2058946A1 (en) | Formulations for the oral administration of drugs with masked taste | |
| IL84167A (en) | Oral delivery of bioactive agents to and through the peyer's patch by use of microencapsulation | |
| EP0211991B1 (de) | Tabletten mit verzögerter Freisetzung sowie Verfahren zu deren Herstellung | |
| DE58903856D1 (de) | Oral zu verabreichende pharmazeutische zubereitung mit kontrollierter wirkstofffreisetzung und verfahren zu deren herstellung. | |
| EP0216743A3 (en) | Galenical forms of verapamil, preparation thereof and medicaments containing them | |
| SE8701479L (sv) | Metod foer inneslutning av biologiskt verksamma preparat samt anvaendning daerav | |
| DE69008107D1 (de) | Zubereitung mit verzögerter Freigabe eines Hydrochlorids eines basischen Arzneistoffs. | |
| IT1153487B (it) | Prodotti farmaceutici in forma-ritardo e procedimento per ottenerli | |
| PT888772E (pt) | Comprimidos de libertacao prolongada a base de valproato metalico | |
| CA2000932A1 (en) | Oral pharmaceutical controlled release multiple unit dosage form | |
| CA1309661C (en) | Transdermal delivery system | |
| ATE18050T1 (de) | Triazolochinazoline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. | |
| ATE110564T1 (de) | Pharmazeutische zusammensetzungen mit verzögerter freisetzung zur oralen verabreichung sowie deren herstellungsverfahren. |