ATE77752T1 - Gegenmittel fuer blut-antikoagulantien auf der grundlage von faktor viii. - Google Patents

Gegenmittel fuer blut-antikoagulantien auf der grundlage von faktor viii.

Info

Publication number
ATE77752T1
ATE77752T1 AT89810733T AT89810733T ATE77752T1 AT E77752 T1 ATE77752 T1 AT E77752T1 AT 89810733 T AT89810733 T AT 89810733T AT 89810733 T AT89810733 T AT 89810733T AT E77752 T1 ATE77752 T1 AT E77752T1
Authority
AT
Austria
Prior art keywords
anticoagulants
factor viii
blood
blood anticoagulants
antidote
Prior art date
Application number
AT89810733T
Other languages
English (en)
Inventor
Valerie Stevenson Findlay
Roger Kerry
Graham Frederick Pay
Robert Brian Wallis
Keith David Butler
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10644806&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE77752(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Application granted granted Critical
Publication of ATE77752T1 publication Critical patent/ATE77752T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/815Protease inhibitors from leeches, e.g. hirudin, eglin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • A61K38/37Factors VIII
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Preparations (AREA)
  • Materials Applied To Surfaces To Minimize Adherence Of Mist Or Water (AREA)
  • Saccharide Compounds (AREA)
  • External Artificial Organs (AREA)
AT89810733T 1988-10-06 1989-09-27 Gegenmittel fuer blut-antikoagulantien auf der grundlage von faktor viii. ATE77752T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888823480A GB8823480D0 (en) 1988-10-06 1988-10-06 Antidote
EP89810733A EP0367713B2 (de) 1988-10-06 1989-09-27 Gegenmittel für Blut-Antikoagulantien auf der Grundlage von Faktor VIII

Publications (1)

Publication Number Publication Date
ATE77752T1 true ATE77752T1 (de) 1992-07-15

Family

ID=10644806

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89810733T ATE77752T1 (de) 1988-10-06 1989-09-27 Gegenmittel fuer blut-antikoagulantien auf der grundlage von faktor viii.

Country Status (13)

Country Link
EP (1) EP0367713B2 (de)
JP (1) JPH02145526A (de)
KR (1) KR0147294B1 (de)
AT (1) ATE77752T1 (de)
AU (1) AU624635B2 (de)
CA (1) CA2000153C (de)
DE (1) DE68901964T2 (de)
DK (1) DK491289A (de)
GB (1) GB8823480D0 (de)
IE (1) IE61361B1 (de)
IL (1) IL91886A (de)
NZ (1) NZ230899A (de)
ZA (1) ZA897586B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL99527A (en) * 1990-09-28 1997-08-14 Lilly Co Eli Tripeptide antithrombotic agents
WO1994008034A1 (fr) * 1992-09-28 1994-04-14 Japan Energy Corporation Nouvelle variante d'hirudine, son procede de production, et anticoagulant la contenant comme ingredient actif
US5972648A (en) * 1993-09-28 1999-10-26 Japan Energy Corporation Hirudin analogs, methods of manufacture thereof and anticoagulant compositions having these as active ingredients
DE4430205A1 (de) * 1994-08-26 1996-02-29 Behringwerke Ag Zusammensetzungen, die als Gegenmittel für Blut-Antikoagulanzien geeignet sind und deren Verwendung
DE4437544A1 (de) 1994-10-20 1996-04-25 Behringwerke Ag Einsatz von vWF-enthaltenden Konzentraten als Kombinationstherapie bei Therapie mit Antithrombotika und Fibrinolytika
WO2025262265A1 (en) 2024-06-21 2025-12-26 Etablissement Francais Du Sang Chimeric molecules comprising an anti-fibrin antibody and an antithrombotic molecule

Also Published As

Publication number Publication date
IE893212L (en) 1990-04-06
GB8823480D0 (en) 1988-11-16
DE68901964T2 (de) 1995-06-14
DK491289A (da) 1990-04-07
CA2000153C (en) 1999-07-13
CA2000153A1 (en) 1990-04-06
EP0367713B1 (de) 1992-07-01
IE61361B1 (en) 1994-11-02
AU4266289A (en) 1990-04-12
EP0367713B2 (de) 1995-01-04
AU624635B2 (en) 1992-06-18
ZA897586B (en) 1990-05-30
KR900005992A (ko) 1990-05-07
DE68901964D1 (de) 1992-08-06
DK491289D0 (da) 1989-10-05
IL91886A (en) 1995-07-31
IL91886A0 (en) 1990-06-10
KR0147294B1 (ko) 1998-08-17
EP0367713A1 (de) 1990-05-09
JPH02145526A (ja) 1990-06-05
NZ230899A (en) 1991-10-25

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee