ATE79542T1 - Verwendung von inositoltriphosphat zur herstellung eines arzneimittels gegen stoerungen bei transplantationen. - Google Patents

Verwendung von inositoltriphosphat zur herstellung eines arzneimittels gegen stoerungen bei transplantationen.

Info

Publication number: ATE79542T1
Authority: AT; Austria
Prior art keywords: manufacture; drug against; inositol triphosphate; against transplantation; transplantation disorders
Prior art date: 1988-09-15

Application number

AT89117031T

Other languages

English (en)

Inventor

Matti Siren

Original Assignee

Perstorp Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-09-15

Filing date

1989-09-14

Publication date

1992-09-15

1989-09-14 Application filed by Perstorp Ab filed Critical Perstorp Ab

1992-09-15 Application granted granted Critical

1992-09-15 Publication of ATE79542T1 publication Critical patent/ATE79542T1/de

Links

239000003814 drug Substances 0.000 title abstract 2
MMWCIQZXVOZEGG-HOZKJCLWSA-N [(1S,2R,3S,4S,5R,6S)-2,3,5-trihydroxy-4,6-diphosphonooxycyclohexyl] dihydrogen phosphate Chemical compound O[C@H]1[C@@H](O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](O)[C@H]1OP(O)(O)=O MMWCIQZXVOZEGG-HOZKJCLWSA-N 0.000 title 1
229940079593 drug Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
238000002054 transplantation Methods 0.000 title 1
MMWCIQZXVOZEGG-UHFFFAOYSA-N 1,4,5-IP3 Natural products OC1C(O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(O)C1OP(O)(O)=O MMWCIQZXVOZEGG-UHFFFAOYSA-N 0.000 abstract 2
MMWCIQZXVOZEGG-XJTPDSDZSA-N D-myo-Inositol 1,4,5-trisphosphate Chemical compound O[C@@H]1[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1OP(O)(O)=O MMWCIQZXVOZEGG-XJTPDSDZSA-N 0.000 abstract 2
102000004895 Lipoproteins Human genes 0.000 abstract 1
108090001030 Lipoproteins Proteins 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
230000002159 abnormal effect Effects 0.000 abstract 1
230000001105 regulatory effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Ophthalmology & Optometry (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Nutrition Science (AREA)
Pain & Pain Management (AREA)
Immunology (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Materials For Medical Uses (AREA)
External Artificial Organs (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT89117031T 1988-09-15 1989-09-14 Verwendung von inositoltriphosphat zur herstellung eines arzneimittels gegen stoerungen bei transplantationen. ATE79542T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE8803248A SE464059C (sv)	1988-09-15	1988-09-15	Användning av inositoltrifosfat för framställning av läkemedel
EP89117031A EP0359259B1 (de)	1988-09-15	1989-09-14	Verwendung von Inositoltriphosphat zur Herstellung eines Arzneimittels gegen Störungen bei Transplantationen

Publications (1)

Publication Number	Publication Date
ATE79542T1 true ATE79542T1 (de)	1992-09-15

Family

ID=20373330

Family Applications (5)

Application Number	Title	Priority Date	Filing Date
AT89117028T ATE84719T1 (de)	1988-09-15	1989-09-14	Verwendung von inositoltriphosphat bei der behandlung der beschaedigung von gewebe.
AT89117029T ATE120958T1 (de)	1988-09-15	1989-09-14	Verwendung von inositoltriphosphat zur herstellung eines arzneimittels gegen diabetes.
AT89117032T ATE88347T1 (de)	1988-09-15	1989-09-14	Verwendung von inositoltriphosphat zur herstellung eines arzneimittels gegen abnorme konzentrationen von lipoproteinen.
AT8989117030T ATE104855T1 (de)	1988-09-15	1989-09-14	Verwendung von inositoltrisphosphat zur herstellung eines arzneimittels gegen knochenerkrakungen.
AT89117031T ATE79542T1 (de)	1988-09-15	1989-09-14	Verwendung von inositoltriphosphat zur herstellung eines arzneimittels gegen stoerungen bei transplantationen.

Family Applications Before (4)

Application Number	Title	Priority Date	Filing Date
AT89117028T ATE84719T1 (de)	1988-09-15	1989-09-14	Verwendung von inositoltriphosphat bei der behandlung der beschaedigung von gewebe.
AT89117029T ATE120958T1 (de)	1988-09-15	1989-09-14	Verwendung von inositoltriphosphat zur herstellung eines arzneimittels gegen diabetes.
AT89117032T ATE88347T1 (de)	1988-09-15	1989-09-14	Verwendung von inositoltriphosphat zur herstellung eines arzneimittels gegen abnorme konzentrationen von lipoproteinen.
AT8989117030T ATE104855T1 (de)	1988-09-15	1989-09-14	Verwendung von inositoltrisphosphat zur herstellung eines arzneimittels gegen knochenerkrakungen.

Country Status (8)

Country	Link
EP (5)	EP0359256B1 (de)
JP (5)	JP3058334B2 (de)
AT (5)	ATE84719T1 (de)
DE (5)	DE68902526T2 (de)
ES (5)	ES2073419T3 (de)
GB (5)	GB2223404B (de)
GR (4)	GR3005448T3 (de)
SE (2)	SE464059C (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5330979A (en) *	1984-10-23	1994-07-19	Perstorp Ab	Method of treating renal disorders with inositoltriphosphate
US5428066A (en) *	1989-03-08	1995-06-27	Larner; Joseph	Method of reducing elevated blood sugar in humans
US5750348A (en) *	1989-03-08	1998-05-12	The University Of Virginia Patents Foundation	Method for detecting insulin resistance
AU647735B2 (en) *	1989-03-08	1994-03-31	University Of Virginia Alumni Patents Foundation, The	Dietary supplement for insulin-resistant diabetics
US5427956A (en) *	1989-03-08	1995-06-27	The University Of Virginia Patent Foundation	Quantitative analysis for diabetic condition predictor
SE9002278L (sv) *	1990-06-28	1991-12-29	Perstorp Ab	Anvaendning av inositoltrisfosfat foer framstaellning av ett laekemedel
SE467340B (sv) *	1990-07-04	1992-07-06	Perstorp Ab	Anvaendning av inositolmonofosfat foer framstaellning av ett laekemedel effektivt som en neuropeptid y-(npy-)antagonist
JP2750239B2 (ja) *	1991-08-14	1998-05-13	三共株式会社	アデノホスチンａまたはｂならびにその製法
SE503122C2 (sv) *	1993-11-22	1996-03-25	Perstorp Ab	Användning av en inositoltrisfosfatester för behandling av inflammatoriska tillstånd
SE9600194D0 (sv) *	1996-01-19	1996-01-19	Perstorp Ab	A new chemical compound
US5880098A (en) *	1996-04-12	1999-03-09	Pharmacia & Upjohn Aktiebolag	Therapeutic treatment
SE9601396D0 (sv) *	1996-04-12	1996-04-12	Dieter Haeussinger	New therapeutic treatment 2
SE9602463D0 (sv) *	1996-06-24	1996-06-24	Perstorp Ab	The use of growth factor modulating compounds
US5998485A (en) *	1997-06-16	1999-12-07	Cedars-Sinai Medical Center	Method for modulating immune response with inositol
US5906979A (en) *	1998-01-27	1999-05-25	Insmed Pharmaceuticals, Inc.	Compositions and methods for treating metabolic diseases characterized by hyperandrogenism and/or anovulation and/or infertility
US6486127B1 (en)	2001-05-23	2002-11-26	Insmed, Incorporated	Compositions comprising D-chiro inositol and lipid lowering compounds and methods of treatment thereof
KR100653557B1 (ko) *	2001-10-06	2006-12-05	아미코젠주식회사	카이로 이노시톨 또는 피니톨의 백내장 예방치료제로서의용도와 그 조성물
KR102666724B1 (ko) *	2017-10-26	2024-05-20	오츠카 세이야쿠 가부시키가이샤	이노시톨인산 함유 조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE465951B (sv) *	1984-10-23	1991-11-25	Perstorp Ab	Isomer av inositoltrifosfat foeretraedesvis i saltform foer anvaendning som terapeutiskt eller profylaktiskt medel samt kompositioner daerav
US4735902A (en) *	1984-10-23	1988-04-05	Matti Siren	Stabilized composition containing inositoltriphosphate
SE465305B (sv) *	1986-04-16	1991-08-26	Perstorp Ab	Anvaendning av inositolfosfat foer framstaellning av ett laekemedel

1988
- 1988-09-15 SE SE8803248A patent/SE464059C/sv not_active IP Right Cessation
1989
- 1989-09-14 JP JP1237431A patent/JP3058334B2/ja not_active Expired - Lifetime
- 1989-09-14 EP EP89117028A patent/EP0359256B1/de not_active Expired - Lifetime
- 1989-09-14 ES ES89117029T patent/ES2073419T3/es not_active Expired - Lifetime
- 1989-09-14 ES ES89117032T patent/ES2054965T3/es not_active Expired - Lifetime
- 1989-09-14 GB GB8920811A patent/GB2223404B/en not_active Expired - Lifetime
- 1989-09-14 EP EP89117031A patent/EP0359259B1/de not_active Expired - Lifetime
- 1989-09-14 AT AT89117028T patent/ATE84719T1/de not_active IP Right Cessation
- 1989-09-14 DE DE8989117031T patent/DE68902526T2/de not_active Expired - Fee Related
- 1989-09-14 AT AT89117029T patent/ATE120958T1/de not_active IP Right Cessation
- 1989-09-14 JP JP1237429A patent/JP2859318B2/ja not_active Expired - Fee Related
- 1989-09-14 EP EP89117032A patent/EP0359260B1/de not_active Expired - Lifetime
- 1989-09-14 ES ES89117028T patent/ES2045319T3/es not_active Expired - Lifetime
- 1989-09-14 GB GB8920805A patent/GB2223168B/en not_active Expired - Lifetime
- 1989-09-14 DE DE89117032T patent/DE68906106T2/de not_active Expired - Fee Related
- 1989-09-14 JP JP1237428A patent/JPH02191218A/ja active Pending
- 1989-09-14 DE DE68922165T patent/DE68922165T2/de not_active Expired - Fee Related
- 1989-09-14 EP EP89117030A patent/EP0359258B1/de not_active Expired - Lifetime
- 1989-09-14 EP EP89117029A patent/EP0359257B1/de not_active Expired - Lifetime
- 1989-09-14 AT AT89117032T patent/ATE88347T1/de not_active IP Right Cessation
- 1989-09-14 AT AT8989117030T patent/ATE104855T1/de not_active IP Right Cessation
- 1989-09-14 ES ES89117031T patent/ES2043998T3/es not_active Expired - Lifetime
- 1989-09-14 AT AT89117031T patent/ATE79542T1/de not_active IP Right Cessation
- 1989-09-14 ES ES89117030T patent/ES2055772T3/es not_active Expired - Lifetime
- 1989-09-14 GB GB8920804A patent/GB2223167B/en not_active Expired - Lifetime
- 1989-09-14 DE DE68914922T patent/DE68914922T2/de not_active Expired - Fee Related
- 1989-09-14 GB GB8920807A patent/GB2223403B/en not_active Expired - Lifetime
- 1989-09-14 GB GB8920806A patent/GB2223169B/en not_active Expired - Lifetime
- 1989-09-14 JP JP1237430A patent/JP2859319B2/ja not_active Expired - Fee Related
- 1989-09-14 DE DE8989117028T patent/DE68904507T2/de not_active Expired - Fee Related
- 1989-09-14 JP JP1237427A patent/JP2547257B2/ja not_active Expired - Fee Related
1990
- 1990-10-24 SE SE9003395A patent/SE9003395L/ not_active Application Discontinuation
1992
- 1992-08-20 GR GR920400982T patent/GR3005448T3/el unknown
1993
- 1993-01-21 GR GR920402459T patent/GR3006825T3/el unknown
- 1993-04-22 GR GR930400188T patent/GR3007686T3/el unknown
1995
- 1995-04-13 GR GR940403975T patent/GR3015764T3/el unknown

Also Published As

Publication number	Publication date
GB2223168B (en)	1992-08-12
DE68922165D1 (de)	1995-05-18
SE464059B (sv)	1991-03-04
JPH02191218A (ja)	1990-07-27
ATE88347T1 (de)	1993-05-15
DE68904507D1 (de)	1993-03-04
DE68906106T2 (de)	1993-10-21
ATE120958T1 (de)	1995-04-15
EP0359256B1 (de)	1993-01-20
JP2859319B2 (ja)	1999-02-17
GB2223404A (en)	1990-04-11
ES2045319T3 (es)	1994-01-16
GB8920807D0 (en)	1989-11-01
GB2223167A (en)	1990-04-04
SE8803248L (sv)	1990-03-16
EP0359258A2 (de)	1990-03-21
EP0359256A3 (en)	1990-10-10
ATE84719T1 (de)	1993-02-15
GB8920811D0 (en)	1989-11-01
ES2054965T3 (es)	1994-08-16
GR3015764T3 (en)	1995-07-31
EP0359258A3 (en)	1990-10-03
SE9003395L (sv)	1992-04-25
ES2043998T3 (es)	1994-01-01
DE68922165T2 (de)	1995-09-14
JP2547257B2 (ja)	1996-10-23
GR3007686T3 (de)	1993-08-31
EP0359257A3 (en)	1990-10-03
GB8920806D0 (en)	1989-11-01
EP0359257B1 (de)	1995-04-12
GR3005448T3 (de)	1993-05-24
JPH02191220A (ja)	1990-07-27
EP0359260B1 (de)	1993-04-21
ES2055772T3 (es)	1994-09-01
DE68904507T2 (de)	1993-06-09
EP0359256A2 (de)	1990-03-21
EP0359259A2 (de)	1990-03-21
SE9003395D0 (sv)	1990-10-24
GB8920804D0 (en)	1989-11-01
DE68914922T2 (de)	1994-09-01
DE68914922D1 (de)	1994-06-01
GR3006825T3 (de)	1993-06-30
DE68902526T2 (de)	1993-03-11
EP0359258B1 (de)	1994-04-27
EP0359259B1 (de)	1992-08-19
JP3058334B2 (ja)	2000-07-04
JPH02191221A (ja)	1990-07-27
GB2223168A (en)	1990-04-04
GB2223403A (en)	1990-04-11
GB2223404B (en)	1992-04-08
ATE104855T1 (de)	1994-05-15
GB2223403B (en)	1992-02-26
SE464059C (sv)	1997-06-02
EP0359260A3 (en)	1990-10-03
ES2073419T3 (es)	1995-08-16
EP0359259A3 (en)	1990-10-03
JP2859318B2 (ja)	1999-02-17
DE68902526D1 (de)	1992-09-24
DE68906106D1 (de)	1993-05-27
EP0359257A2 (de)	1990-03-21
SE8803248D0 (sv)	1988-09-15
GB2223169A (en)	1990-04-04
JPH02191219A (ja)	1990-07-27
EP0359260A2 (de)	1990-03-21
GB8920805D0 (en)	1989-11-01
JPH02191217A (ja)	1990-07-27
GB2223167B (en)	1992-02-26
GB2223169B (en)	1992-04-08

Legal Events

Date	Code	Title	Description
1993-04-15	UEP	Publication of translation of european patent specification
2004-06-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE79542T1 (de)	1992-09-15	Verwendung von inositoltriphosphat zur herstellung eines arzneimittels gegen stoerungen bei transplantationen.
DE59109222D1 (de)	2001-11-22	Verwendung des Wirkstoffs Flupirtin zur Herstellung eines Arzneimittels zur Bekämpfung von Muskelverspannungen
ES2077655T3 (es)	1995-12-01	Membrana multicapa para un deposito que puede implantarse.
DE69113848D1 (de)	1995-11-23	Verwendung von Phosphatidylglycerol(diC 18:10) zur Behandlung obstruktiver Atemwegserkrankungen.
ATE143260T1 (de)	1996-10-15	Verwendung von (s)-isofluran und (s)-desfluran zur anästhesie sowie entsprechende arzneimittelzubereitungen
ES2060239T3 (es)	1994-11-16	Analogos de bis(alquil-sustituido-4-hidroxifeniltio)alcano como inhibidores de la formacion de cataratas.
ATE232387T1 (de)	2003-02-15	Verwendung eines inositoltriphosphatester, zur herstellung eines medikamentes
DE69301750D1 (de)	1996-04-18	Verwendung von 1-Alpha,24(R)-Dihydroxy-22(E)-Dehydrovitamin-D3 zur Herstellung eines Arzneimittels zur Behandlung der Osteoporose
ATE98127T1 (de)	1993-12-15	Verwendung von peroxidlipiden zur herstellung eines arzneimittels zur behandlung von kreislaufinsuffizienz bei lokaler applikation.