ATE79882T1 - ANTIBACTERIAL COMPOUNDS. - Google Patents

ANTIBACTERIAL COMPOUNDS.

Info

Publication number
ATE79882T1
ATE79882T1 AT8585104687T AT85104687T ATE79882T1 AT E79882 T1 ATE79882 T1 AT E79882T1 AT 8585104687 T AT8585104687 T AT 8585104687T AT 85104687 T AT85104687 T AT 85104687T AT E79882 T1 ATE79882 T1 AT E79882T1
Authority
AT
Austria
Prior art keywords
optionally substituted
antibacterial compounds
optionally
fuzed
methoxy
Prior art date
Application number
AT8585104687T
Other languages
German (de)
Inventor
Akio Miyake
Masahiro Kondo
Masahiko Fujino
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1984/000270 external-priority patent/WO1985005620A1/en
Priority claimed from PCT/JP1985/000102 external-priority patent/WO1986005184A1/en
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority claimed from EP85104687A external-priority patent/EP0160252B1/en
Application granted granted Critical
Publication of ATE79882T1 publication Critical patent/ATE79882T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Novel cephem compounds of general formula (I), wherein R1 represents and optionally amino group, R2 represents H or halogen, R3 represents H or an optionally substituted hydrocarbon residue, R4 represents H or methoxy, A represents an optionally substituted imidazol-l-yl group forming a fuzed ring at positions 2 and 3 or 3 and 4, and n represents 0 or 1. They have an excellent antibacterial activity.
AT8585104687T 1984-04-23 1985-04-18 ANTIBACTERIAL COMPOUNDS. ATE79882T1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/JP1984/000212 WO1985004879A1 (en) 1984-04-23 1984-04-23 Cephem compounds
PCT/JP1984/000270 WO1985005620A1 (en) 1984-05-25 1984-05-25 Cephem compounds
PCT/JP1985/000102 WO1986005184A1 (en) 1985-03-01 1985-03-01 Antibacterial compound
EP85104687A EP0160252B1 (en) 1984-04-23 1985-04-18 Antibacterial compounds

Publications (1)

Publication Number Publication Date
ATE79882T1 true ATE79882T1 (en) 1992-09-15

Family

ID=13818317

Family Applications (1)

Application Number Title Priority Date Filing Date
AT8585104687T ATE79882T1 (en) 1984-04-23 1985-04-18 ANTIBACTERIAL COMPOUNDS.

Country Status (6)

Country Link
AT (1) ATE79882T1 (en)
DK (1) DK179985A (en)
HU (1) HU195966B (en)
MY (1) MY102089A (en)
WO (1) WO1985004879A1 (en)
ZA (1) ZA853017B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4496896A (en) * 1995-01-30 1996-08-21 Takeda Chemical Industries Ltd. Cephem compounds, their production and use

Also Published As

Publication number Publication date
DK179985D0 (en) 1985-04-22
HU195966B (en) 1988-08-29
DK179985A (en) 1985-10-24
MY102089A (en) 1992-03-31
WO1985004879A1 (en) 1985-11-07
HUT40444A (en) 1986-12-28
ZA853017B (en) 1986-12-30

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