ATE80292T1 - SPHERICAL GRANULES WITH A CORE AND THEIR PRODUCTION. - Google Patents

SPHERICAL GRANULES WITH A CORE AND THEIR PRODUCTION.

Info

Publication number
ATE80292T1
ATE80292T1 AT88300569T AT88300569T ATE80292T1 AT E80292 T1 ATE80292 T1 AT E80292T1 AT 88300569 T AT88300569 T AT 88300569T AT 88300569 T AT88300569 T AT 88300569T AT E80292 T1 ATE80292 T1 AT E80292T1
Authority
AT
Austria
Prior art keywords
core
production
spherical granules
granules
spherical
Prior art date
Application number
AT88300569T
Other languages
German (de)
Inventor
Tadashi Makino
Tetsuro Tabata
Shin-Ichiro Hirai
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority claimed from EP88300569A external-priority patent/EP0277741B1/en
Application granted granted Critical
Publication of ATE80292T1 publication Critical patent/ATE80292T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
AT88300569T 1987-01-29 1988-01-25 SPHERICAL GRANULES WITH A CORE AND THEIR PRODUCTION. ATE80292T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1917887 1987-01-29
EP88300569A EP0277741B1 (en) 1987-01-29 1988-01-25 Spherical granules having core and their production

Publications (1)

Publication Number Publication Date
ATE80292T1 true ATE80292T1 (en) 1992-09-15

Family

ID=26115617

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88300569T ATE80292T1 (en) 1987-01-29 1988-01-25 SPHERICAL GRANULES WITH A CORE AND THEIR PRODUCTION.

Country Status (2)

Country Link
AT (1) ATE80292T1 (en)
GR (1) GR3023599T3 (en)

Also Published As

Publication number Publication date
GR3023599T3 (en) 1997-08-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time