ATE81005T1 - Ponalrestat enthaltendes hyperurikaemie-mittel. - Google Patents

Ponalrestat enthaltendes hyperurikaemie-mittel.

Info

Publication number: ATE81005T1
Authority: AT; Austria
Prior art keywords: ponalrestat; hyperuricaemia; agent; phthalazin; fluorobenzyl
Prior art date: 1987-02-26

Application number

AT88301379T

Other languages

English (en)

Inventor

Per Trygve Thyrum

Original Assignee

Ici America Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-02-26

Filing date

1988-02-18

Publication date

1992-10-15

1988-02-18 Application filed by Ici America Inc filed Critical Ici America Inc

1992-10-15 Application granted granted Critical

1992-10-15 Publication of ATE81005T1 publication Critical patent/ATE81005T1/de

Links

LKBFFDOJUKLQNY-UHFFFAOYSA-N 2-[3-[(4-bromo-2-fluorophenyl)methyl]-4-oxo-1-phthalazinyl]acetic acid Chemical compound O=C1C2=CC=CC=C2C(CC(=O)O)=NN1CC1=CC=C(Br)C=C1F LKBFFDOJUKLQNY-UHFFFAOYSA-N 0.000 title abstract 2
201000001431 Hyperuricemia Diseases 0.000 title 1
229950010884 ponalrestat Drugs 0.000 title 1
LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 abstract 1
TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
210000002966 serum Anatomy 0.000 abstract 1
229940124597 therapeutic agent Drugs 0.000 abstract 1
229940116269 uric acid Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Physical Education & Sports Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Fats And Perfumes (AREA)
Semiconductor Lasers (AREA)
Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
Saccharide Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Enzymes And Modification Thereof (AREA)

AT88301379T 1987-02-26 1988-02-18 Ponalrestat enthaltendes hyperurikaemie-mittel. ATE81005T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB878704569A GB8704569D0 (en)	1987-02-26	1987-02-26	Therapeutic agent
EP88301379A EP0296695B1 (de)	1987-02-26	1988-02-18	Ponalrestat enthaltendes Hyperurikämie-Mittel

Publications (1)

Publication Number	Publication Date
ATE81005T1 true ATE81005T1 (de)	1992-10-15

Family

ID=10613007

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88301379T ATE81005T1 (de)	1987-02-26	1988-02-18	Ponalrestat enthaltendes hyperurikaemie-mittel.

Country Status (12)

Country	Link
US (1)	US4895843A (de)
EP (1)	EP0296695B1 (de)
JP (1)	JPH01216931A (de)
KR (1)	KR880009653A (de)
AT (1)	ATE81005T1 (de)
DE (1)	DE3874978T2 (de)
DK (1)	DK169304B1 (de)
ES (1)	ES2052701T3 (de)
GB (2)	GB8704569D0 (de)
GR (1)	GR3006256T3 (de)
HU (1)	HU197845B (de)
IE (1)	IE61934B1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5064830A (en) *	1990-08-02	1991-11-12	Pfizer Inc.	Lowering of blood uric acid levels
EP2848252A3 (de)	2007-03-23	2015-06-17	The Board of Regents of the University of Texas System	Aldose-Reduktase-Inhibitoren zur Behandlung von Uveitis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE47592B1 (en) *	1977-12-29	1984-05-02	Ici Ltd	Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture

1987
- 1987-02-26 GB GB878704569A patent/GB8704569D0/en active Pending
1988
- 1988-02-09 US US07/154,019 patent/US4895843A/en not_active Expired - Fee Related
- 1988-02-18 ES ES88301379T patent/ES2052701T3/es not_active Expired - Lifetime
- 1988-02-18 EP EP88301379A patent/EP0296695B1/de not_active Expired - Lifetime
- 1988-02-18 AT AT88301379T patent/ATE81005T1/de not_active IP Right Cessation
- 1988-02-18 GB GB8803763A patent/GB2201343B/en not_active Expired - Lifetime
- 1988-02-18 DE DE8888301379T patent/DE3874978T2/de not_active Expired - Fee Related
- 1988-02-24 HU HU88872A patent/HU197845B/hu not_active IP Right Cessation
- 1988-02-25 IE IE51588A patent/IE61934B1/en not_active IP Right Cessation
- 1988-02-25 DK DK099488A patent/DK169304B1/da not_active IP Right Cessation
- 1988-02-26 KR KR1019880002083A patent/KR880009653A/ko not_active Ceased
- 1988-02-26 JP JP63044019A patent/JPH01216931A/ja active Pending
1992
- 1992-11-16 GR GR920402597T patent/GR3006256T3/el unknown

Also Published As

Publication number	Publication date
HU197845B (en)	1989-06-28
DK99488D0 (da)	1988-02-25
IE61934B1 (en)	1994-11-30
JPH01216931A (ja)	1989-08-30
EP0296695A2 (de)	1988-12-28
HUT46213A (en)	1988-10-28
GB2201343B (en)	1990-11-14
DE3874978T2 (de)	1993-02-18
DE3874978D1 (de)	1992-11-05
US4895843A (en)	1990-01-23
ES2052701T3 (es)	1994-07-16
DK169304B1 (da)	1994-10-10
EP0296695B1 (de)	1992-09-30
GB2201343A (en)	1988-09-01
GB8803763D0 (en)	1988-03-16
IE880515L (en)	1988-08-26
KR880009653A (ko)	1988-10-04
GB8704569D0 (en)	1987-04-01
EP0296695A3 (en)	1990-07-18
DK99488A (da)	1988-08-27
GR3006256T3 (de)	1993-06-21

Legal Events

Date	Code	Title	Description
1993-03-15	UEP	Publication of translation of european patent specification
1997-11-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
MY103352A (en)	1993-06-30	Piperazinyl-heterocyclic compounds
PT1020460E (pt)	2009-07-29	Sal de sódio do enantiómero (-) de omeprazole
IT1218548B (it)	1990-04-19	Perno autofilettante per l'impianto di protesi dentali
LU88842I2 (fr)	1997-01-27	Nebivolol optionnellement sous forme d'un sel ou d'un hydrate pharmaceutiquement acceptable en particulier hydroclorure de Nebivolol
EP0276536A3 (en)	1989-08-30	Use of buspirone for the improvement of short term memory
DE69007246D1 (de)	1994-04-14	Polyvinylphosphonsäure enthaltender Glasionomerzement.
IT1222395B (it)	1990-09-05	Composizione farmaceutica per somministrazione intranasale comprendente l'ormone ghrh,un agonista colinergico e/o un sale biliare
MY103210A (en)	1993-05-29	Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds.
FI880944L (fi)	1988-09-03	Kombinationsterapi varvid man anvaender antitumoer immunotoxiner tillsammans med tumoersnekrosfaktor.
GR3003555T3 (de)	1993-03-16
ATE81005T1 (de)	1992-10-15	Ponalrestat enthaltendes hyperurikaemie-mittel.
GR3004848T3 (de)	1993-04-28
WO1986006960A3 (en)	1987-01-29	Use of nicorandil or pinacidil for the treatment of peripheral vascular disease
DE3775057D1 (de)	1992-01-16	Knickfederkoerper.
IT8763326V0 (it)	1987-11-10	Presidio medico per l'elettromagnetoterapia.
DK530388D0 (da)	1988-09-23	Pyrrolo-(1,2-b)cinnoliner og farmaceutisk acceptable salte deraf, deres fremstilling og anvendelse
EP0191814A4 (de)	1987-03-16	Absorptionsverbesserer für proteine.
FI880513A0 (fi)	1988-02-04	Anordning foer foeljande med en patients livsfunktioner.
FR2609388B1 (fr)	1997-04-04	Inserts de courbes d'arcades dentaires
NO870417D0 (no)	1987-02-03	Oppdriftslegemer for boelgedempere.
KR890002218U (ko)	1989-03-28	환자침대의 경사각도 조절용 핸들
FI881838A7 (fi)	1989-10-21	Terapeutiskt aktiv foerening.
IT210122Z2 (it)	1988-11-14	Cyclette per handicappati.
DK231489D0 (da)	1989-05-12	Azacykliske carboxylsyrederivater, deres fremstilling og anvendelse
FI871533A0 (fi)	1987-04-08	Daeck med infaellda dubbar.