ATE81006T1 - Verfahren zur anwendung von diltiazem, verapamil oder nifedipin mit aktivitaet zur behandlung von schlaganfaellen. - Google Patents

Verfahren zur anwendung von diltiazem, verapamil oder nifedipin mit aktivitaet zur behandlung von schlaganfaellen.

Info

Publication number: ATE81006T1
Authority: AT; Austria
Prior art keywords: diltiazem; verapamil; activity; nifedipin; administration
Prior art date: 1986-01-10

Application number

AT87100195T

Other languages

English (en)

Inventor

Frank W Marcoux

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-10

Filing date

1987-01-09

Publication date

1992-10-15

1987-01-09 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

1992-10-15 Application granted granted Critical

1992-10-15 Publication of ATE81006T1 publication Critical patent/ATE81006T1/de

Links

SGTNSNPWRIOYBX-UHFFFAOYSA-N 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile Chemical compound C1=C(OC)C(OC)=CC=C1CCN(C)CCCC(C#N)(C(C)C)C1=CC=C(OC)C(OC)=C1 SGTNSNPWRIOYBX-UHFFFAOYSA-N 0.000 title abstract 2
HSUGRBWQSSZJOP-RTWAWAEBSA-N diltiazem Chemical compound C1=CC(OC)=CC=C1[C@H]1[C@@H](OC(C)=O)C(=O)N(CCN(C)C)C2=CC=CC=C2S1 HSUGRBWQSSZJOP-RTWAWAEBSA-N 0.000 title abstract 2
229960004166 diltiazem Drugs 0.000 title abstract 2
229960001722 verapamil Drugs 0.000 title abstract 2
208000006011 Stroke Diseases 0.000 abstract 1
HYIMSNHJOBLJNT-UHFFFAOYSA-N nifedipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1[N+]([O-])=O HYIMSNHJOBLJNT-UHFFFAOYSA-N 0.000 abstract 1
229960001597 nifedipine Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Hospice & Palliative Care (AREA)
Vascular Medicine (AREA)
Psychiatry (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

AT87100195T 1986-01-10 1987-01-09 Verfahren zur anwendung von diltiazem, verapamil oder nifedipin mit aktivitaet zur behandlung von schlaganfaellen. ATE81006T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/818,505 US4654372A (en)	1986-01-10	1986-01-10	Method for using verapamil for treating stroke
EP87100195A EP0229644B1 (de)	1986-01-10	1987-01-09	Verfahren zur Anwendung von Diltiazem, Verapamil oder Nifedipin mit Aktivität zur Behandlung von Schlaganfällen

Publications (1)

Publication Number	Publication Date
ATE81006T1 true ATE81006T1 (de)	1992-10-15

Family

ID=25225695

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT87100195T ATE81006T1 (de)	1986-01-10	1987-01-09	Verfahren zur anwendung von diltiazem, verapamil oder nifedipin mit aktivitaet zur behandlung von schlaganfaellen.

Country Status (8)

Country	Link
US (1)	US4654372A (de)
EP (1)	EP0229644B1 (de)
JP (1)	JPS62167725A (de)
AT (1)	ATE81006T1 (de)
CA (1)	CA1284950C (de)
DE (1)	DE3781904T2 (de)
ES (1)	ES2046178T3 (de)
GR (1)	GR3005998T3 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4871731A (en) *	1987-10-07	1989-10-03	Marion Laboratories, Inc.	Captopril and diltiazem composition and the like
DE3737741A1 (de) *	1987-11-06	1989-05-18	Goedecke Ag	Oral anzuwendende arzneiform zur einmal taeglichen behandlung der hypertonie mit diltiazemhydrochlorid
DK0429676T3 (de) *	1989-06-16	1997-03-10	Santen Pharmaceutical Co Ltd
RU1804845C (ru) *	1991-02-15	1993-03-30	Институт Органического Синтеза Латвийской Ан	Ноотропное вещество
US5695781A (en) *	1995-03-01	1997-12-09	Hallmark Pharmaceuticals, Inc.	Sustained release formulation containing three different types of polymers
US6083532A (en) *	1995-03-01	2000-07-04	Duramed Pharmaceuticals, Inc.	Sustained release formulation containing three different types of polymers and tablet formed therefrom
ES2289814T3 (es) *	1998-07-10	2008-02-01	Novartis Pharma Ag	Combinacion antihipertensiva de valsartan y bloqueador de canales del calcio.
EP2066323A2 (de) *	2006-09-12	2009-06-10	NeuroSearch AS	Pharmazeutische zusammensetzungen mit kombinationen aus einer antagonistischen ampa-/kainat-verbindung und einem hemmer eines multdrug-resistenzproteins
US20220125754A1 (en) *	2019-01-29	2022-04-28	Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)	Treating the causative agent in adhesiogenesis
EP4136103A4 (de) *	2020-04-17	2024-05-15	HB Biotech, Inc.	Zusammensetzungen und verfahren zur behandlung neuropsychiatrischer erkrankungen
WO2026002967A1 (en)	2024-06-24	2026-01-02	Universität Linz	Leoligin and derivatives thereof as calcium channel blockers for the prevention and/or treatment of related diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4568677A (en) *	1983-07-23	1986-02-04	Pfizer Inc.	2-(4-Pyrimidone alkoxyalkyl) dihydropyridine anti-ischaemic and antihypertensive agents
JPS60130517A (ja) *	1983-12-16	1985-07-12	Mitsui Pharmaceut Inc	アレルギ−性鼻炎治療剤

1986
- 1986-01-10 US US06/818,505 patent/US4654372A/en not_active Expired - Fee Related
- 1986-11-07 CA CA000522469A patent/CA1284950C/en not_active Expired - Fee Related
1987
- 1987-01-09 JP JP62001981A patent/JPS62167725A/ja active Pending
- 1987-01-09 DE DE8787100195T patent/DE3781904T2/de not_active Expired - Fee Related
- 1987-01-09 EP EP87100195A patent/EP0229644B1/de not_active Expired - Lifetime
- 1987-01-09 ES ES87100195T patent/ES2046178T3/es not_active Expired - Lifetime
- 1987-01-09 AT AT87100195T patent/ATE81006T1/de not_active IP Right Cessation
1992
- 1992-10-15 GR GR920402317T patent/GR3005998T3/el unknown

Also Published As

Publication number	Publication date
ES2046178T3 (es)	1995-04-01
EP0229644B1 (de)	1992-09-30
US4654372A (en)	1987-03-31
DE3781904T2 (de)	1993-02-25
DE3781904D1 (de)	1992-11-05
JPS62167725A (ja)	1987-07-24
CA1284950C (en)	1991-06-18
EP0229644A2 (de)	1987-07-22
GR3005998T3 (de)	1993-06-07
EP0229644A3 (en)	1989-11-23

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Legal Events

Date	Code	Title	Description
1993-04-15	UEP	Publication of translation of european patent specification
1995-10-15	REN	Ceased due to non-payment of the annual fee