ATE8143T1 - 3,4-dihydroxyphenyltetrahydrothienopyridine. - Google Patents
3,4-dihydroxyphenyltetrahydrothienopyridine.Info
- Publication number
- ATE8143T1 ATE8143T1 AT81302247T AT81302247T ATE8143T1 AT E8143 T1 ATE8143 T1 AT E8143T1 AT 81302247 T AT81302247 T AT 81302247T AT 81302247 T AT81302247 T AT 81302247T AT E8143 T1 ATE8143 T1 AT E8143T1
- Authority
- AT
- Austria
- Prior art keywords
- dihydroxyphenyltetrahydrothienopyridine
- dihydroxyphenyltetrahydrothieno
- tetrahydrothieno
- thienylmethyl
- dihydroxyphenyl
- Prior art date
Links
- UXXGBPYUULIGHX-UHFFFAOYSA-N 4-(2,3,3a,4-tetrahydrothieno[3,2-b]pyridin-2-yl)benzene-1,2-diol Chemical compound C1=C(O)C(O)=CC=C1C1SC2=CC=CNC2C1 UXXGBPYUULIGHX-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000003222 pyridines Chemical class 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/152,253 US4282227A (en) | 1980-05-22 | 1980-05-22 | Renal vasodilating 3,4-dihydroxyphenyltetrahydrothienopyridines |
| EP81302247A EP0040955B1 (de) | 1980-05-22 | 1981-05-21 | 3,4-Dihydroxyphenyltetrahydrothienopyridine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE8143T1 true ATE8143T1 (de) | 1984-07-15 |
Family
ID=22542144
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT81302247T ATE8143T1 (de) | 1980-05-22 | 1981-05-21 | 3,4-dihydroxyphenyltetrahydrothienopyridine. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4282227A (de) |
| EP (1) | EP0040955B1 (de) |
| JP (1) | JPS5716884A (de) |
| AT (1) | ATE8143T1 (de) |
| DE (1) | DE3164412D1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL71661A0 (en) * | 1983-04-27 | 1984-07-31 | Boehringer Ingelheim Kg | 4-phenyl-tetrahydro-furano-pyridines,their preparation and pharmaceutical compositions containing them |
| US4876261A (en) * | 1987-03-27 | 1989-10-24 | Akihiro Tanaka | Substituted tetrahydroisoquinoline compounds and composition containing them |
| PT690863E (pt) * | 1993-04-06 | 2003-07-31 | Abbott Lab | Compostos tetraciclicos como agonistas da dopamina |
| US5668141A (en) * | 1996-04-02 | 1997-09-16 | Abbott Laboratories | Trans-2,6-,3,6-and 4,6-diaza-5,6,6a,7,8,12b-hexahydrobenzo[c]phenanthrene compounds as dopamine agonists |
| AU2003217430B2 (en) * | 2002-02-15 | 2008-10-23 | Darpharma, Inc. | Mono-ester and asymmetrically substituted Di-ester pro-drugs of the dopamine D1 receptor agonists |
| CN102391244A (zh) * | 2011-09-21 | 2012-03-28 | 天津理工大学 | 一种3-取代胺甲基噻吩化合物的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3520895A (en) * | 1968-02-16 | 1970-07-21 | Colgate Palmolive Co | 1-substituted-1,2,3,4-tetrahydrobenzothieno(2,3-c)pyridines |
| FR2358150A1 (fr) * | 1976-07-13 | 1978-02-10 | Parcor | Nouvelles thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application |
| FR2423494A1 (fr) * | 1977-06-02 | 1979-11-16 | Parcor | Benzo (b) thieno pyridines, leur procede de preparation et leurs applications therapeutiques |
| AT368504B (de) * | 1977-10-15 | 1982-10-25 | Boehringer Sohn Ingelheim | Verfahren zur herstellung neuer 4-phenyl-thieno- (2,3-c)-piperidine |
| DE2746443C2 (de) * | 1977-10-15 | 1986-09-18 | C.H. Boehringer Sohn, 6507 Ingelheim | 4-Phenyl-thieno-[2,3-c]-piperidine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen |
-
1980
- 1980-05-22 US US06/152,253 patent/US4282227A/en not_active Expired - Lifetime
-
1981
- 1981-05-18 JP JP7477381A patent/JPS5716884A/ja active Pending
- 1981-05-21 EP EP81302247A patent/EP0040955B1/de not_active Expired
- 1981-05-21 AT AT81302247T patent/ATE8143T1/de not_active IP Right Cessation
- 1981-05-21 DE DE8181302247T patent/DE3164412D1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0040955B1 (de) | 1984-06-27 |
| EP0040955A3 (en) | 1982-01-06 |
| US4282227A (en) | 1981-08-04 |
| DE3164412D1 (en) | 1984-08-02 |
| JPS5716884A (en) | 1982-01-28 |
| EP0040955A2 (de) | 1981-12-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |