ATE81458T1 - Bakterizide pharmazeutische zusammensetzung. - Google Patents

Bakterizide pharmazeutische zusammensetzung.

Info

Publication number: ATE81458T1
Authority: AT; Austria
Prior art keywords: general formula; weight; pharmaceutical composition; chem; hydrogen
Prior art date: 1987-07-20

Application number

AT88306598T

Other languages

English (en)

Inventor

Gabor Kulcsar

Peter Sarkozy

Judit Frank

Katalin Kaloy

Original Assignee

Chinoin Gyogyszer Es Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-07-20

Filing date

1988-07-19

Publication date

1992-10-15

1988-07-19 Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet

1992-10-15 Application granted granted Critical

1992-10-15 Publication of ATE81458T1 publication Critical patent/ATE81458T1/de

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
230000000844 anti-bacterial effect Effects 0.000 title 1
-1 piperazino Chemical group 0.000 abstract 4
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
SNLMOXFUCILIPL-UHFFFAOYSA-N 1,8-naphthyridine-2-carboxylic acid Chemical class C1=CC=NC2=NC(C(=O)O)=CC=C21 SNLMOXFUCILIPL-UHFFFAOYSA-N 0.000 abstract 1
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
229920000858 Cyclodextrin Polymers 0.000 abstract 1
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
229920002472 Starch Polymers 0.000 abstract 1
239000004098 Tetracycline Substances 0.000 abstract 1
239000000654 additive Substances 0.000 abstract 1
230000000845 anti-microbial effect Effects 0.000 abstract 1
239000004599 antimicrobial Substances 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
239000003995 emulsifying agent Substances 0.000 abstract 1
229910052731 fluorine Inorganic materials 0.000 abstract 1
239000011737 fluorine Substances 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 abstract 1
239000001095 magnesium carbonate Substances 0.000 abstract 1
229910000021 magnesium carbonate Inorganic materials 0.000 abstract 1
235000014380 magnesium carbonate Nutrition 0.000 abstract 1
235000019359 magnesium stearate Nutrition 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
229910052757 nitrogen Chemical group 0.000 abstract 1
LOAUVZALPPNFOQ-UHFFFAOYSA-N quinaldic acid Chemical class C1=CC=CC2=NC(C(=O)O)=CC=C21 LOAUVZALPPNFOQ-UHFFFAOYSA-N 0.000 abstract 1
HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1
239000008107 starch Substances 0.000 abstract 1
235000019698 starch Nutrition 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
230000002195 synergetic effect Effects 0.000 abstract 1
239000000454 talc Substances 0.000 abstract 1
229910052623 talc Inorganic materials 0.000 abstract 1
235000012222 talc Nutrition 0.000 abstract 1
229960002180 tetracycline Drugs 0.000 abstract 1
229930101283 tetracycline Natural products 0.000 abstract 1
235000019364 tetracycline Nutrition 0.000 abstract 1
150000003522 tetracyclines Chemical class 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT88306598T 1987-07-20 1988-07-19 Bakterizide pharmazeutische zusammensetzung. ATE81458T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU873335A HU200917B (en)	1987-07-20	1987-07-20	Process for producing pharmaceutical compositions comprising quinoline or naphthyridinecarboxylic acid and tetracycline derivatives as active ingredient
EP88306598A EP0300735B1 (de)	1987-07-20	1988-07-19	Bakterizide pharmazeutische Zusammensetzung

Publications (1)

Publication Number	Publication Date
ATE81458T1 true ATE81458T1 (de)	1992-10-15

Family

ID=10963614

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88306598T ATE81458T1 (de)	1987-07-20	1988-07-19	Bakterizide pharmazeutische zusammensetzung.

Country Status (14)

Country	Link
US (1)	US4904647A (de)
EP (1)	EP0300735B1 (de)
JP (1)	JPS6490125A (de)
KR (1)	KR890001553A (de)
CN (1)	CN1031797A (de)
AT (1)	ATE81458T1 (de)
AU (1)	AU609676B2 (de)
DE (1)	DE3875295T2 (de)
ES (1)	ES2043827T3 (de)
GR (1)	GR3006560T3 (de)
HK (1)	HK71093A (de)
HU (1)	HU200917B (de)
IL (1)	IL87144A (de)
RU (1)	RU2030913C1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5328908A (en) *	1988-10-24	1994-07-12	Procter & Gamble Pharmaceuticals, Inc.	Antimicrobial quinolone thioureas
US5180719A (en) *	1988-10-24	1993-01-19	Norwich Eaton Pharmaceuticals, Inc.	Antimicrobial quinolonyl lactam esters
CA2001203C (en) *	1988-10-24	2001-02-13	Thomas P. Demuth, Jr.	Novel antimicrobial dithiocarbamoyl quinolones
EP0997466A1 (de) *	1988-10-24	2000-05-03	PROCTER & GAMBLE PHARMACEUTICALS, INC.	Antimikrobielle Laktamchinolone
US5491139A (en) *	1988-10-24	1996-02-13	The Procter & Gamble Company	Antimicrobial quinolonyl lactams
US5273973A (en) *	1988-10-24	1993-12-28	Norwich Eaton Pharmaceuticals, Inc.	Antimicrobial quinolonyl esters
DK0525057T3 (da) *	1990-04-18	2000-07-31	Procter & Gamble Pharma	Antimikrobielle quinolonyllactamer
US5420272A (en) *	1992-08-13	1995-05-30	American Cyanamid Company	7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
KR100371092B1 (ko) *	1999-12-09	2003-02-05	주식회사대성미생물연구소	동물용 복합항균제 조성물
EP1305048A2 (de) *	2000-08-01	2003-05-02	Wockhardt Limited	Ausfluss-pump-inhibitoren von mikroben
US7098219B2 (en)	2000-08-01	2006-08-29	Wockhart Limited	Inhibitors of cellular efflux pumps of microbes
US6878713B2 (en)	2001-04-25	2005-04-12	Wockhardt Limited	Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6964966B2 (en)	2001-04-25	2005-11-15	Wockhardt Limited	Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US20030181371A1 (en) *	2001-12-28	2003-09-25	Angiotech Pharmaceuticals, Inc.	Compositions and methods of using collajolie
US20040192658A1 (en) *	2002-12-27	2004-09-30	Angiotech International Ag	Compositions and methods of using collajolie
EP1660495B1 (de)	2003-09-04	2007-07-11	Wockhardt Limited	Benzochinolizin-2-carbonsäureargininsalz- tetrahydrat

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3497594A (en) *	1967-06-01	1970-02-24	Pfizer & Co C	Combinations of quinoxaline-di-n-oxides and tetracycline antibiotics
US4147788A (en) *	1976-02-23	1979-04-03	E. I. Dupont De Nemours And Company	Antibacterials: 1-difluoromethyl-6,7-methylenedioxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid and its esters
CH642850A5 (it) *	1978-10-20	1984-05-15	Ausonia Farma Srl	Composizioni farmaceutiche ad attivita antibatterica contro infezioni da germi gram-positivi e gram-negativi.
US4517191A (en) *	1983-09-29	1985-05-14	Sterling Drug Inc.	1-Amino-1,8-naphthyridine compounds useful as bactericides
HU190963B (en) *	1984-04-28	1986-12-28	Allatorvostudomanyi Egyetem,Hu	Process for production of synergyc medical preparatives containing organic acids with oxitetracylin and antimicrobatic influence

1987
- 1987-07-20 HU HU873335A patent/HU200917B/hu not_active IP Right Cessation
1988
- 1988-07-18 IL IL8714488A patent/IL87144A/en not_active IP Right Cessation
- 1988-07-19 ES ES88306598T patent/ES2043827T3/es not_active Expired - Lifetime
- 1988-07-19 AT AT88306598T patent/ATE81458T1/de not_active IP Right Cessation
- 1988-07-19 KR KR1019880009013A patent/KR890001553A/ko not_active Ceased
- 1988-07-19 AU AU19147/88A patent/AU609676B2/en not_active Ceased
- 1988-07-19 DE DE8888306598T patent/DE3875295T2/de not_active Expired - Fee Related
- 1988-07-19 EP EP88306598A patent/EP0300735B1/de not_active Expired - Lifetime
- 1988-07-19 CN CN88106698A patent/CN1031797A/zh active Pending
- 1988-07-20 JP JP63181438A patent/JPS6490125A/ja active Pending
- 1988-07-20 US US07/222,056 patent/US4904647A/en not_active Expired - Fee Related
1991
- 1991-11-22 RU SU915010098A patent/RU2030913C1/ru active
1992
- 1992-12-16 GR GR920402934T patent/GR3006560T3/el unknown
1993
- 1993-07-22 HK HK710/93A patent/HK71093A/en unknown

Also Published As

Publication number	Publication date
DE3875295T2 (de)	1993-02-25
EP0300735A1 (de)	1989-01-25
ES2043827T3 (es)	1994-01-01
CN1031797A (zh)	1989-03-22
EP0300735B1 (de)	1992-10-14
US4904647A (en)	1990-02-27
GR3006560T3 (de)	1993-06-30
KR890001553A (ko)	1989-03-27
HK71093A (en)	1993-07-30
IL87144A (en)	1994-04-12
AU609676B2 (en)	1991-05-02
IL87144A0 (en)	1988-12-30
HU200917B (en)	1990-09-28
RU2030913C1 (ru)	1995-03-20
DE3875295D1 (de)	1992-11-19
HUT47844A (en)	1989-04-28
JPS6490125A (en)	1989-04-06
AU1914788A (en)	1989-01-27

Legal Events

Date	Code	Title	Description
1993-03-15	UEP	Publication of translation of european patent specification
1997-04-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE3875295D1 (de)	1992-11-19	Bakterizide pharmazeutische zusammensetzung.
HU9401415D0 (en)	1994-08-29	Enzofuranyl- and -thiophenyl-alkane-carboxylic acid derivatives, pharmaceutical compositions contaning them, and process for producing them
AU3461697A (en)	1998-02-10	Heterocyclic compounds, their production and use
IL85236A0 (en)	1988-07-31	Microbicidal and fungicidal compositions containing thiazole derivatives,certain such novel compounds and their preparation
IL114785A0 (en)	1995-11-27	Pyrrolocarbazoles their preparation and pharmaceutical compositions containing them
DE69416739D1 (de)	1999-04-08	Tetrazinderivate mit akarizider Wirkung
ZA894508B (en)	1990-03-28	Pharmaceutical compounds
TW222277B (de)	1994-04-11
IL83841A (en)	1991-11-21	5-membered heterocyclic ring compounds substituted by phenyl and pyrrolidin-2-yl,their preparation and pharmaceutical compositions containing them
WO1991000729A3 (en)	1991-06-13	Bis-dioxopiperazines, and their use as protecting agents
NO175253C (no)	1994-09-21	Forbindelse, anvendelse og preparat
IL88415A0 (en)	1989-06-30	1,4-disubstituted-piperidinyl compounds and compositions containing them
HU902079D0 (en)	1990-08-28	Process for producing glutaric acid derivatives and pharmaceutical preparatives containing such compounds
ES550972A0 (es)	1987-06-01	Un procedimiento para preparar nuevos derivados de imidiazol.
GR3005900T3 (de)	1993-06-07
ES8704895A1 (es)	1987-04-16	Un metodo para preparar 1-aminoalquilamino-4-ariloxipiperidinas sustituidas
DE3362523D1 (en)	1986-04-17	Optically active imidazolylpropanol compounds, and their production and use
GR3004321T3 (de)	1993-03-31
EP0178580A3 (en)	1987-03-18	Intermediates for the synthesis of carboxylic acids
HUT42271A (en)	1987-07-28	Fungicidal compositions and process for preparing azolyl-(aryloxymethyl)-dimethyl-pentinol derivatives applicable as active substance