ATE81983T1 - Absorptionsverbesserer fuer proteine. - Google Patents
Absorptionsverbesserer fuer proteine.Info
- Publication number
- ATE81983T1 ATE81983T1 AT85904049T AT85904049T ATE81983T1 AT E81983 T1 ATE81983 T1 AT E81983T1 AT 85904049 T AT85904049 T AT 85904049T AT 85904049 T AT85904049 T AT 85904049T AT E81983 T1 ATE81983 T1 AT E81983T1
- Authority
- AT
- Austria
- Prior art keywords
- proteins
- absorption enhancers
- absorption
- preferably hydroxylamine
- administering
- Prior art date
Links
- 238000010521 absorption reaction Methods 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 239000003623 enhancer Substances 0.000 title 1
- WTDHULULXKLSOZ-UHFFFAOYSA-N Hydroxylamine hydrochloride Chemical compound Cl.ON WTDHULULXKLSOZ-UHFFFAOYSA-N 0.000 abstract 2
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000007721 medicinal effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
- A61K38/446—Superoxide dismutase (1.15)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/638,695 US4658830A (en) | 1984-08-08 | 1984-08-08 | Method and apparatus for initiating reperfusion treatment by an unattended individual undergoing heart attack symptoms |
| US06/708,845 US4661469A (en) | 1984-08-08 | 1985-03-06 | t-PA composition capable of being absorbed into the blood stream and method of administration |
| US71670585A | 1985-03-27 | 1985-03-27 | |
| PCT/US1985/001504 WO1986001109A1 (en) | 1984-08-08 | 1985-08-08 | Protein absorption enhancing agents |
| EP85904049A EP0191814B1 (de) | 1984-08-08 | 1985-08-08 | Absorptionsverbesserer für proteine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE81983T1 true ATE81983T1 (de) | 1992-11-15 |
Family
ID=27417624
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85904049T ATE81983T1 (de) | 1984-08-08 | 1985-08-08 | Absorptionsverbesserer fuer proteine. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0191814B1 (de) |
| AT (1) | ATE81983T1 (de) |
| AU (1) | AU591069B2 (de) |
| CA (1) | CA1264030A (de) |
| DE (1) | DE3586795T2 (de) |
| IL (1) | IL76121A0 (de) |
| WO (1) | WO1986001109A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4661469A (en) * | 1984-08-08 | 1987-04-28 | Survival Technology, Inc. | t-PA composition capable of being absorbed into the blood stream and method of administration |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3551554A (en) * | 1968-08-16 | 1970-12-29 | Crown Zellerbach Corp | Enhancing tissue penetration of physiologically active agents with dmso |
| US4305947A (en) * | 1980-08-26 | 1981-12-15 | Survival Technology, Inc. | Stable aqueous solutions of pralidoxime salts |
| US4661469A (en) * | 1984-08-08 | 1987-04-28 | Survival Technology, Inc. | t-PA composition capable of being absorbed into the blood stream and method of administration |
| EP0201153A3 (de) * | 1985-02-09 | 1987-10-07 | Beecham Group Plc | Modifiziertes Enzym und Verfahren zu dessen Herstellung |
-
1985
- 1985-08-08 DE DE8585904049T patent/DE3586795T2/de not_active Expired - Fee Related
- 1985-08-08 AU AU47211/85A patent/AU591069B2/en not_active Ceased
- 1985-08-08 CA CA000488317A patent/CA1264030A/en not_active Expired
- 1985-08-08 AT AT85904049T patent/ATE81983T1/de not_active IP Right Cessation
- 1985-08-08 WO PCT/US1985/001504 patent/WO1986001109A1/en not_active Ceased
- 1985-08-08 EP EP85904049A patent/EP0191814B1/de not_active Expired
- 1985-08-18 IL IL76121A patent/IL76121A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0191814A4 (de) | 1987-03-16 |
| EP0191814B1 (de) | 1992-11-04 |
| DE3586795D1 (de) | 1992-12-10 |
| IL76121A0 (en) | 1985-12-31 |
| AU4721185A (en) | 1986-03-07 |
| DE3586795T2 (de) | 1993-05-19 |
| WO1986001109A1 (en) | 1986-02-27 |
| AU591069B2 (en) | 1989-11-30 |
| EP0191814A1 (de) | 1986-08-27 |
| CA1264030A (en) | 1989-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |