ATE82286T1 - Heterocyclische derivate. - Google Patents

Heterocyclische derivate.

Info

Publication number: ATE82286T1
Authority: AT; Austria
Prior art keywords: alkyl; optionally substituted; thiazole; substituted; alkynyl
Prior art date: 1989-01-30

Application number

AT90300780T

Other languages

English (en)

Inventor

Graham Charles Crawley

Martin Paul Edwards

Original Assignee

Ici Plc

Ici Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-01-30

Filing date

1990-01-25

Publication date

1992-11-15

1990-01-25 Application filed by Ici Plc, Ici Pharma filed Critical Ici Plc

1992-11-15 Application granted granted Critical

1992-11-15 Publication of ATE82286T1 publication Critical patent/ATE82286T1/de

Links

125000000217 alkyl group Chemical group 0.000 abstract 4
FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical compound C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 abstract 3
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
125000003342 alkenyl group Chemical group 0.000 abstract 2
125000000304 alkynyl group Chemical group 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
RAHZWNYVWXNFOC-UHFFFAOYSA-N Sulphur dioxide Chemical group O=S=O RAHZWNYVWXNFOC-UHFFFAOYSA-N 0.000 abstract 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
125000002618 bicyclic heterocycle group Chemical group 0.000 abstract 1
125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000002950 monocyclic group Chemical group 0.000 abstract 1
-1 oxy, thio, sulphinyl Chemical group 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
125000000335 thiazolyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Thiazole And Isothizaole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT90300780T 1989-01-30 1990-01-25 Heterocyclische derivate. ATE82286T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP89400251		1989-01-30

Publications (1)

Publication Number	Publication Date
ATE82286T1 true ATE82286T1 (de)	1992-11-15

Family

ID=8202915

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90300780T ATE82286T1 (de)	1989-01-30	1990-01-25	Heterocyclische derivate.

Country Status (13)

Country	Link
US (2)	US5089495A (de)
EP (1)	EP0381375B1 (de)
JP (1)	JPH03197471A (de)
AT (1)	ATE82286T1 (de)
AU (1)	AU626977B2 (de)
CA (1)	CA2007654A1 (de)
DE (1)	DE69000438T2 (de)
DK (1)	DK0381375T3 (de)
ES (1)	ES2053095T3 (de)
GR (1)	GR3006324T3 (de)
IE (1)	IE62558B1 (de)
NZ (1)	NZ232094A (de)
ZA (1)	ZA90264B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5196422A (en) *	1988-07-12	1993-03-23	Ici Pharma	5-lipoxygenase inhibiting thiazoles
US5254581A (en) *	1990-06-21	1993-10-19	Imperial Chemical Industries Plc	Pyran derivatives and their use as inhibitors of 5-lipoxygenase
IE914005A1 (en) *	1990-12-14	1992-06-17	Zeneca Ltd	Novel intermediates
DE4139751A1 (de) *	1991-12-03	1993-06-09	Bayer Ag, 5090 Leverkusen, De	Thiazolyl substituierte chinolylmethoxyphenylessigsaeurederivate
US5281720A (en) *	1991-02-28	1994-01-25	Merck Frosst Canada, Inc.	Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis
GB9122590D0 (en) *	1991-10-24	1991-12-04	Lilly Industries Ltd	Pharmaceutical compounds
WO1993016081A1 (en) *	1992-02-13	1993-08-19	Merrell Dow Pharmaceuticals Inc.	Piperidinyl thiacyclic derivatives
US5308852A (en) *	1992-06-29	1994-05-03	Merck Frosst Canada, Inc.	Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis
US5428060A (en) *	1992-08-27	1995-06-27	Merck Frosst Canada, Inc.	Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis
US5252599A (en) *	1992-08-27	1993-10-12	Merck Frosst Canada, Inc.	Heteroarylnaphthalene hydroxy acids as inhibitors of leukotriene biosynthesis
US5426109A (en) *	1992-08-27	1995-06-20	Merck Frosst Canada, Inc.	Phenylnaphthalene hydroxy acids
US5350744A (en) *	1992-08-27	1994-09-27	Merck Frosst Canada, Inc.	Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis
EP0632027A1 (de) *	1993-07-01	1995-01-04	BASF Aktiengesellschaft	6-(Carbonyloxymethylene)-Chinoline
DE4411657A1 (de) *	1994-04-02	1995-10-05	Basf Ag	Verfahren zur Herstellung von 6-Hydroxymethylchinolinen
US5552437A (en) *	1994-10-27	1996-09-03	Merck Frosst Canada, Inc.	Bisarylcarbinol derivatives as inhibitors of leukotriene biosynthesis
US5527827A (en) *	1994-10-27	1996-06-18	Merck Frosst Canada, Inc.	Bisarylcarbinol cinnamic acids as inhibitors of leukotriene biosynthesis
AU1820002A (en) *	2000-10-03	2002-04-15	Syngenta Participations Ag	Phenylpropynyloxypyridine herbicides
US6548670B1 (en)	2001-07-19	2003-04-15	Air Products And Chemicals, Inc.	Methods for preparing 5- and 6-benzyl-functionalized quinoxalines
US6825221B2 (en)	2001-10-18	2004-11-30	Allergan, Inc.	Arylsulfanyl and heteroarylsulfanyl derivatives for treating pain

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE56702B1 (en) *	1982-12-01	1991-11-06	Usv Pharma Corp	Antiinflammatory antiallergic compounds
NO174506B (no) *	1984-10-30	1994-02-07	Usv Pharma Corp	Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser
US4721721A (en) *	1984-12-18	1988-01-26	Rorer Pharmaceutical Corporation	6-(4-thiazole) compounds, cardiotonic compositions including the same, and their uses
US4839369A (en) *	1985-04-16	1989-06-13	Rorer Pharmaceutical Corporation	Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4876346A (en) *	1985-05-02	1989-10-24	American Home Products Corporation	Quinoline compounds
US4661499A (en) *	1985-06-18	1987-04-28	Merck Frosst Canada, Inc.	2-[(substituted)-phenoxymethyl]quinolines
JPS62142168A (ja) *	1985-10-16	1987-06-25	Mitsubishi Chem Ind Ltd	チアゾ−ル誘導体及びそれを有効成分とするロイコトリエンきつ抗剤
AU612569B2 (en) *	1986-03-13	1991-07-18	Rorer International (Overseas) Inc.	Quinolinyl ether or thioether tetrazoles as agents for the treatment of hypersensitive ailments
GB8820389D0 (en) *	1988-08-26	1988-09-28	Beecham Group Plc	Novel compounds
IL93343A0 (en) *	1989-02-28	1990-11-29	Ici Plc	Heterocyclic cycloalkanes
IL93344A0 (en) *	1989-02-28	1990-11-29	Ici Plc	Heterocyclic cyclic ethers

1990
- 1990-01-10 US US07/463,267 patent/US5089495A/en not_active Expired - Fee Related
- 1990-01-12 NZ NZ232094A patent/NZ232094A/en unknown
- 1990-01-12 CA CA002007654A patent/CA2007654A1/en not_active Abandoned
- 1990-01-12 IE IE14490A patent/IE62558B1/en not_active IP Right Cessation
- 1990-01-15 ZA ZA90264A patent/ZA90264B/xx unknown
- 1990-01-18 AU AU48596/90A patent/AU626977B2/en not_active Ceased
- 1990-01-25 DE DE9090300780T patent/DE69000438T2/de not_active Expired - Fee Related
- 1990-01-25 ES ES90300780T patent/ES2053095T3/es not_active Expired - Lifetime
- 1990-01-25 DK DK90300780.5T patent/DK0381375T3/da active
- 1990-01-25 AT AT90300780T patent/ATE82286T1/de active
- 1990-01-25 EP EP90300780A patent/EP0381375B1/de not_active Expired - Lifetime
- 1990-01-30 JP JP2018114A patent/JPH03197471A/ja active Pending
1991
- 1991-11-18 US US07/793,557 patent/US5283245A/en not_active Expired - Fee Related
1992
- 1992-11-24 GR GR920402688T patent/GR3006324T3/el unknown

Also Published As

Publication number	Publication date
ZA90264B (en)	1990-10-31
JPH03197471A (ja)	1991-08-28
IE900144L (en)	1990-07-30
EP0381375B1 (de)	1992-11-11
AU4859690A (en)	1990-08-02
DE69000438T2 (de)	1993-03-25
CA2007654A1 (en)	1990-07-30
AU626977B2 (en)	1992-08-13
IE62558B1 (en)	1995-02-08
NZ232094A (en)	1992-06-25
GR3006324T3 (de)	1993-06-21
DK0381375T3 (da)	1993-01-25
EP0381375A1 (de)	1990-08-08
ES2053095T3 (es)	1994-07-16
DE69000438D1 (de)	1992-12-17
US5283245A (en)	1994-02-01
US5089495A (en)	1992-02-18

Publication	Publication Date	Title
DE69000438D1 (de)	1992-12-17	Heterocyclische derivate.
IL95481A0 (en)	1991-06-30	Heterocyclic derivatives and pharmaceutical compositions containing them
HUT58083A (en)	1992-01-28	Process for producing heterocyclic compounds and pharmaceutical compositions comprising such compounds
DK346089A (da)	1990-01-13	Heterocykliske forbindelser
NO900917L (no)	1990-08-29	Fremgangsmaate for fremstilling av terapeutisk aktive heterocykliske cykloalkaner.
FI901010A0 (fi)	1990-02-28	Heterocykliska cykliska etrar.