ATE8252T1 - Pharmakologisch wirksame pentapeptid derivate. - Google Patents

Pharmakologisch wirksame pentapeptid derivate.

Info

Publication number
ATE8252T1
ATE8252T1 AT81304860T AT81304860T ATE8252T1 AT E8252 T1 ATE8252 T1 AT E8252T1 AT 81304860 T AT81304860 T AT 81304860T AT 81304860 T AT81304860 T AT 81304860T AT E8252 T1 ATE8252 T1 AT E8252T1
Authority
AT
Austria
Prior art keywords
cys
met
hydrogen
hse
eth
Prior art date
Application number
AT81304860T
Other languages
English (en)
Inventor
Paul David Gesellchen
Robert Theodore Shuman
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Application granted granted Critical
Publication of ATE8252T1 publication Critical patent/ATE8252T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C07K14/702—Enkephalins with at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
AT81304860T 1980-10-20 1981-10-19 Pharmakologisch wirksame pentapeptid derivate. ATE8252T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/198,896 US4322339A (en) 1980-10-20 1980-10-20 Pharmacologically active peptides

Publications (1)

Publication Number Publication Date
ATE8252T1 true ATE8252T1 (de) 1984-07-15

Family

ID=22735325

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81304860T ATE8252T1 (de) 1980-10-20 1981-10-19 Pharmakologisch wirksame pentapeptid derivate.

Country Status (22)

Country Link
US (1) US4322339A (de)
EP (1) EP0050503B1 (de)
JP (1) JPS57108051A (de)
KR (1) KR830007517A (de)
AT (1) ATE8252T1 (de)
AU (1) AU7657581A (de)
CA (1) CA1187872A (de)
DD (1) DD200799A5 (de)
DE (1) DE3164594D1 (de)
DK (1) DK461581A (de)
ES (1) ES8301203A1 (de)
FI (1) FI813199A7 (de)
GB (1) GB2085892B (de)
GR (1) GR75824B (de)
HU (1) HU185321B (de)
IL (1) IL64084A0 (de)
NZ (1) NZ198626A (de)
PL (1) PL131156B1 (de)
PT (1) PT73840B (de)
RO (1) RO83297B (de)
YU (1) YU249181A (de)
ZA (1) ZA817062B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2702711A1 (de) 1976-02-02 1977-08-04 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
EP0044451B1 (de) * 1980-07-17 1984-04-18 Sandoz Ag Pentapeptide, Verfahren zu deren Herstellung, deren pharmazeutische Zusammensetzungen und deren Anwendung
FR2488253A1 (fr) * 1980-08-08 1982-02-12 Roques Bernard Nouveaux peptides et leur application en therapeutique
DK134784A (da) * 1983-03-07 1984-09-08 Lilly Co Eli Farmakologisk virksomme tripeptid-derivater og fremgangsmaade til fremstilling deraf
GB8314646D0 (en) * 1983-05-26 1983-06-29 Wellcome Found Pharmaceutical amides
US4495178A (en) * 1983-10-06 1985-01-22 G. D. Searle & Co. Enkephalin analogs
US4599325A (en) * 1984-02-16 1986-07-08 G. D. Searle & Co. Substituted tyrosyl alanine dipeptide amides
US6028168A (en) 1991-08-09 2000-02-22 Winfried Kolbeck Lanthionine bridged peptides
US6258550B1 (en) 1993-04-23 2001-07-10 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5952465A (en) * 1993-04-23 1999-09-14 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5928896A (en) * 1993-04-23 1999-07-27 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
AU6770794A (en) * 1993-04-23 1994-11-21 Herbert J. Evans Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5965698A (en) * 1993-04-23 1999-10-12 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
US6084066A (en) * 1993-10-29 2000-07-04 Virginia Commonwealth University Polypetides that include conformation-constraining groups which flank a protein-protein interaction site

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1577115A (en) * 1976-07-27 1980-10-22 Reckitt & Colmann Prod Ltd Container closure units
CH619686A5 (en) * 1976-02-02 1980-10-15 Sandoz Ag Process for the preparation of novel peptides or peptide derivatives
DE2702711A1 (de) * 1976-02-02 1977-08-04 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
US4259234A (en) * 1976-09-27 1981-03-31 Eli Lilly And Company Analgesic compounds
US4283329A (en) * 1979-12-17 1981-08-11 Eli Lilly And Company Pharmacologically active peptides

Also Published As

Publication number Publication date
HU185321B (en) 1985-01-28
ES506315A0 (es) 1982-12-01
NZ198626A (en) 1984-02-03
PT73840A (en) 1981-11-01
GB2085892B (en) 1984-03-07
FI813199L (fi) 1982-04-21
GB2085892A (en) 1982-05-06
US4322339A (en) 1982-03-30
DD200799A5 (de) 1983-06-15
DK461581A (da) 1982-05-19
AU7657581A (en) 1982-04-29
GR75824B (de) 1984-08-02
ZA817062B (en) 1983-05-25
RO83297B (ro) 1984-02-28
PT73840B (en) 1983-01-17
KR830007517A (ko) 1983-10-21
FI813199A7 (fi) 1982-04-21
ES8301203A1 (es) 1982-12-01
IL64084A0 (en) 1982-01-31
CA1187872A (en) 1985-05-28
PL131156B1 (en) 1984-10-31
RO83297A (ro) 1984-02-21
JPS57108051A (en) 1982-07-05
EP0050503B1 (de) 1984-07-04
YU249181A (en) 1983-12-31
PL233499A1 (de) 1982-05-24
EP0050503A1 (de) 1982-04-28
DE3164594D1 (en) 1984-08-09

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee